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The map label for this gene is helD [C]

Identifier: 116620814

GI number: 116620814

Start: 2112674

End: 2114086

Strand: Direct

Name: helD [C]

Synonym: Acid_1695

Alternate gene names: 116620814

Gene position: 2112674-2114086 (Clockwise)

Preceding gene: 116620813

Following gene: 116620824

Centisome position: 21.2

GC content: 54.14

Gene sequence:

>1413_bases
ATGACGACGACCGCACAGCGCGATGTCACTCTTACGCCTCAGCAAAGTGAGTGCGTGAACTACAGCAGCCGGAGTCTACT
GATCCGGGGCGTTCCAGGCAGCGGAAAGACAGTCGTGCTGCTGCGGCGGGCACGCAAGTTTGCCGAGTCAGACAACTGCT
GTACGGTTCGAATACTCACGTACAATCGGACGCTGGCGAGATTTGCTGGCGAGCTAGTAGCCCAATTAAACCGTCCACAA
ATTCAAGTGATGACATTTCACTCGTGGGCACAGAAAGCCACGACGGCTGTGATGGGCTTTAGGCGCGTAGTTTCGGCGCC
CGTTAGGCGAGAGCTTATTGAAAGGTATGTTGCAGAGGCGAAGGCGGCTTCACCAGCCAATACCCTTCTCGCTCGCGAGT
TTGAATTTTGGCGGGATGAGATCGCCTGGATCAAAGGCAGCCTGATCGGGAGAGAAACCGACTACCTGGCCGCGGAACGA
AGAGGGCGGGGATCGGCTCTGAAAGCCGCTGACCGTTCGGTGGCCTGGTCCGTGTACATGCGGTATCAGCGAGCATTGGA
AAGGAGCCAAAAGGTAGATTGGGAAGACTACGGGCGTGTGCTCCTCGATCGTATCGATCAATGGCCCGCCCGGCTCTATT
GCGATCATGTCCTTGTTGACGAGGCTCAGGACTTGCACCCGAATCAGTTAGCAGTTCTTGGCAGGATGGCAAAAAGAAGT
CTTACAATCGCGGCGGACGAAGGCCAGAAGATCTACAAAACCGCATTTGCATGGTCAGACTTGGGAATCAATGTGCGCGG
AGGGGGCAGTAAGAGGCTAGGGCAGACGTTCAGATCTACTCGGCAGATTATAGGGCTCGCCAACTGTCTGAGACTGCGTG
ACCGGCGCGAAAATGGTTCTGCTGAAGAGAGCGAGCTTTATGATTTGCCCGATATCGAGGGGCCTCGTCCTGCTGTATGG
AACGTAGGGACAGAGCTGAAAGAAGAAGAGGTCACTATTGGCATCGTAAAGGGGTTGCTACATGACCAACCTGATGCGAC
AATCGGGCTACTTGCCAGAAGCTGGGACACGCTCTACCGGTTTAATGCTCTGTTTCGAGAACATCGATTACCCTTCGGTT
TTATCAAAGACGATGACGGCGCCGCCATTACGACGGCCGGCATCAAATTGAGCACATTCCACGGCGCTAAGGGTTTGGAG
TTCGACTTCGTGATAATCTCCCGGTTTTCGGAGAACACTACGCCACCCCGTGCCGATACGGGCGCCGATGAGATCGATTT
AAGCGTGGAACGCAGACTCATATATGTATCAATGACCAGGGCGAAATTTGGCCTGTTCTTTACGTATTCAGGGAAACCGT
CGCCATTTATTGAAGAGTTCGACCCGTCGCTGTACGACGCAAAGTCGGTGTAA

Upstream 100 bases:

>100_bases
GGGCAGACGTCGCCGCGCGCCTTGGACAGATGGCAGAATATGAAACAGCCGCCAAAGTGAGACCAGCACTCGATGAGATT
CTCTCGGACGAGGACGAAGA

Downstream 100 bases:

>100_bases
TTCGAATTGAAACTGCCTCCGGAGATCCGGACTTCGATCTTGTGAACTGCCACGACTTACGGAGGCGGGGTTCTCGCGAC
AACACCCGTCACTCCTCCGG

Product: putative DNA helicase

Products: Separated DNA [C]

Alternate protein names: DNA Helicase; LexA Repressor; Helicase; Plasmid Stabilization System; NERD Domain-Containing Protein; UvrD/Rep Helicase; Superfamily I DNA/RNA Helicase-Like Protein; UvrD/REP Helicase Domain Protein; Superfamily I Helicase; Superfamily Protein I DNA/RNA Helicase; UvrD/REP Type DNA Helicase; UvrD/REP Family ATP-Dependent DNA Helicase; NA Helicase.; DNA Helicase II-Like Protein; Peptidase; Superfamily I DNA And RNA Helicase-Like Protein; Uvrd/Rep Helicase; NERD Domain Protein; DNA Helicase II; Superfamily I DNA/RNA Helicase

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTTTAQRDVTLTPQQSECVNYSSRSLLIRGVPGSGKTVVLLRRARKFAESDNCCTVRILTYNRTLARFAGELVAQLNRPQ
IQVMTFHSWAQKATTAVMGFRRVVSAPVRRELIERYVAEAKAASPANTLLAREFEFWRDEIAWIKGSLIGRETDYLAAER
RGRGSALKAADRSVAWSVYMRYQRALERSQKVDWEDYGRVLLDRIDQWPARLYCDHVLVDEAQDLHPNQLAVLGRMAKRS
LTIAADEGQKIYKTAFAWSDLGINVRGGGSKRLGQTFRSTRQIIGLANCLRLRDRRENGSAEESELYDLPDIEGPRPAVW
NVGTELKEEEVTIGIVKGLLHDQPDATIGLLARSWDTLYRFNALFREHRLPFGFIKDDDGAAITTAGIKLSTFHGAKGLE
FDFVIISRFSENTTPPRADTGADEIDLSVERRLIYVSMTRAKFGLFFTYSGKPSPFIEEFDPSLYDAKSV

Sequences:

>Translated_470_residues
MTTTAQRDVTLTPQQSECVNYSSRSLLIRGVPGSGKTVVLLRRARKFAESDNCCTVRILTYNRTLARFAGELVAQLNRPQ
IQVMTFHSWAQKATTAVMGFRRVVSAPVRRELIERYVAEAKAASPANTLLAREFEFWRDEIAWIKGSLIGRETDYLAAER
RGRGSALKAADRSVAWSVYMRYQRALERSQKVDWEDYGRVLLDRIDQWPARLYCDHVLVDEAQDLHPNQLAVLGRMAKRS
LTIAADEGQKIYKTAFAWSDLGINVRGGGSKRLGQTFRSTRQIIGLANCLRLRDRRENGSAEESELYDLPDIEGPRPAVW
NVGTELKEEEVTIGIVKGLLHDQPDATIGLLARSWDTLYRFNALFREHRLPFGFIKDDDGAAITTAGIKLSTFHGAKGLE
FDFVIISRFSENTTPPRADTGADEIDLSVERRLIYVSMTRAKFGLFFTYSGKPSPFIEEFDPSLYDAKSV
>Mature_469_residues
TTTAQRDVTLTPQQSECVNYSSRSLLIRGVPGSGKTVVLLRRARKFAESDNCCTVRILTYNRTLARFAGELVAQLNRPQI
QVMTFHSWAQKATTAVMGFRRVVSAPVRRELIERYVAEAKAASPANTLLAREFEFWRDEIAWIKGSLIGRETDYLAAERR
GRGSALKAADRSVAWSVYMRYQRALERSQKVDWEDYGRVLLDRIDQWPARLYCDHVLVDEAQDLHPNQLAVLGRMAKRSL
TIAADEGQKIYKTAFAWSDLGINVRGGGSKRLGQTFRSTRQIIGLANCLRLRDRRENGSAEESELYDLPDIEGPRPAVWN
VGTELKEEEVTIGIVKGLLHDQPDATIGLLARSWDTLYRFNALFREHRLPFGFIKDDDGAAITTAGIKLSTFHGAKGLEF
DFVIISRFSENTTPPRADTGADEIDLSVERRLIYVSMTRAKFGLFFTYSGKPSPFIEEFDPSLYDAKSV

Specific function: Helicase IV Catalyzes The Unwinding Of Duplex DNA In The 3' To 5' Direction With Respect To The Bound Single Strand In A Reaction That Is Dependent Upon The Hydrolysis Of ATP. [C]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 53075; Mature: 52944

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTAQRDVTLTPQQSECVNYSSRSLLIRGVPGSGKTVVLLRRARKFAESDNCCTVRILT
CCCCCCCCEEECCCHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHHHCCCCCCEEEEEEE
YNRTLARFAGELVAQLNRPQIQVMTFHSWAQKATTAVMGFRRVVSAPVRRELIERYVAEA
CCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KAASPANTLLAREFEFWRDEIAWIKGSLIGRETDYLAAERRGRGSALKAADRSVAWSVYM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RYQRALERSQKVDWEDYGRVLLDRIDQWPARLYCDHVLVDEAQDLHPNQLAVLGRMAKRS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCE
LTIAADEGQKIYKTAFAWSDLGINVRGGGSKRLGQTFRSTRQIIGLANCLRLRDRRENGS
EEEEECCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AEESELYDLPDIEGPRPAVWNVGTELKEEEVTIGIVKGLLHDQPDATIGLLARSWDTLYR
CCHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FNALFREHRLPFGFIKDDDGAAITTAGIKLSTFHGAKGLEFDFVIISRFSENTTPPRADT
HHHHHHHHCCCEEEEECCCCCEEEECCEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCC
GADEIDLSVERRLIYVSMTRAKFGLFFTYSGKPSPFIEEFDPSLYDAKSV
CCCCEEEEEEEEEEEEEEECCEEEEEEEECCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTTAQRDVTLTPQQSECVNYSSRSLLIRGVPGSGKTVVLLRRARKFAESDNCCTVRILT
CCCCCCCEEECCCHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHHHCCCCCCEEEEEEE
YNRTLARFAGELVAQLNRPQIQVMTFHSWAQKATTAVMGFRRVVSAPVRRELIERYVAEA
CCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KAASPANTLLAREFEFWRDEIAWIKGSLIGRETDYLAAERRGRGSALKAADRSVAWSVYM
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RYQRALERSQKVDWEDYGRVLLDRIDQWPARLYCDHVLVDEAQDLHPNQLAVLGRMAKRS
HHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCE
LTIAADEGQKIYKTAFAWSDLGINVRGGGSKRLGQTFRSTRQIIGLANCLRLRDRRENGS
EEEEECCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AEESELYDLPDIEGPRPAVWNVGTELKEEEVTIGIVKGLLHDQPDATIGLLARSWDTLYR
CCHHHCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FNALFREHRLPFGFIKDDDGAAITTAGIKLSTFHGAKGLEFDFVIISRFSENTTPPRADT
HHHHHHHHCCCEEEEECCCCCEEEECCEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCC
GADEIDLSVERRLIYVSMTRAKFGLFFTYSGKPSPFIEEFDPSLYDAKSV
CCCCEEEEEEEEEEEEEEECCEEEEEEEECCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Duplex DNA; DNA [C]

Specific reaction: Catalyzes the unwinding and separation of duplex DNA in vivo Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA