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The map label for this gene is wza [H]

Identifier: 116620766

GI number: 116620766

Start: 2040876

End: 2041904

Strand: Direct

Name: wza [H]

Synonym: Acid_1647

Alternate gene names: 116620766

Gene position: 2040876-2041904 (Clockwise)

Preceding gene: 116620762

Following gene: 116620767

Centisome position: 20.48

GC content: 60.74

Gene sequence:

>1029_bases
ATGAGAACGGCGACGCTAATCCTACTACTTGCTGTCGTGCCAATCTTCGCCGCCCCACAGGATCGGGCCAAATCTAAATC
CGAAGGAACCCAGAACTCCGCCATGCCCCCAGGGGCTGCGCCTCGATTTGAGGCCATCCCGGCGAGCGTGACGGCAGGCC
AGGCGACGCAATTGACGTGGACCGTGGAAGGCGCAACCAGCGTCAACATTCAGCCGGTGGTGGGTAGCGTGCCCGCATCC
GGATCTGCGCCGGTGACGCCGGGAGAGACGACGACCTACACCTTGACTGCGGTGCTGCCTTCGGGCAACGTGACCGCCAC
CACTACCGTGACGGTGGCACTCGCTGGGCCGGGAACGACTCCGCCCTCGACGGAGCTGCCGTCACCCGCTACCACGAGTC
CTTCCAGCATGGCGGTTCCCGCACCTTCGGCTGCCACTTCGGCGATGCCGGAAGCGCCTAAGGCGACCGCGCCGACCATC
GATCCGACCAAGATGGGCGCGCCGCGTGACGGAACGACTAAGCCGCCGGCGAAAGTGGACGATCATGCTTTCATCCTGGG
CGCGGAAGACCAGATCGCGATCTCGGTTTACGGCAGTCCTGAATTCAGCGGCTCGCACATGATCCGGCCGGATGGCAAGA
TCACGCTCAACTTTATCGGCGAAGTAACCGCGACCGACCTTACGCCGGAGCAACTGAGTAACGAGATCAAGGAACGCATT
AAGAAGTACATCGTGGATCCCGACGTCAGCGTTCAAGTGCTGGCGGTGCGCAGCAAGAAGTACTTCATCCAGGGCGAAGT
CGGGCGTACGGGCGAGTTCCCGTTGACGGTGCCGACGCGCGTACTGGAAGCTCTCGTGAACGCAGGCGGCTTCAAGGACT
TCGCGAATAAGAAGAACATCATCATTATGCGCGGCACCGACATGCGCGGCACGCAGCGGATCAGGTTCAATTACAACGAA
GTCATCAAGGGCAAACATCTGGAGCAGAATATATATCTGCAGCCCGGCGACATCATTTTGGTTCGCTAA

Upstream 100 bases:

>100_bases
CCTCTGGATGCTGTACACTATGTGGAGTGAGTCGAGCCTCACTCTTTTTTTTGCGAGAAGCGCAGGCCGCATTGCCGGTC
GAATCATCCGAGGTACATTC

Downstream 100 bases:

>100_bases
CCGAAAGAGCGAGACGGAGGAGACATGGCAGCAGCTCAAAATTTTGTAACCGTTTCCCGGCGTCCACCGGATATTGAAGA
CTATATCGACATGCTACGGC

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRTATLILLLAVVPIFAAPQDRAKSKSEGTQNSAMPPGAAPRFEAIPASVTAGQATQLTWTVEGATSVNIQPVVGSVPAS
GSAPVTPGETTTYTLTAVLPSGNVTATTTVTVALAGPGTTPPSTELPSPATTSPSSMAVPAPSAATSAMPEAPKATAPTI
DPTKMGAPRDGTTKPPAKVDDHAFILGAEDQIAISVYGSPEFSGSHMIRPDGKITLNFIGEVTATDLTPEQLSNEIKERI
KKYIVDPDVSVQVLAVRSKKYFIQGEVGRTGEFPLTVPTRVLEALVNAGGFKDFANKKNIIIMRGTDMRGTQRIRFNYNE
VIKGKHLEQNIYLQPGDIILVR

Sequences:

>Translated_342_residues
MRTATLILLLAVVPIFAAPQDRAKSKSEGTQNSAMPPGAAPRFEAIPASVTAGQATQLTWTVEGATSVNIQPVVGSVPAS
GSAPVTPGETTTYTLTAVLPSGNVTATTTVTVALAGPGTTPPSTELPSPATTSPSSMAVPAPSAATSAMPEAPKATAPTI
DPTKMGAPRDGTTKPPAKVDDHAFILGAEDQIAISVYGSPEFSGSHMIRPDGKITLNFIGEVTATDLTPEQLSNEIKERI
KKYIVDPDVSVQVLAVRSKKYFIQGEVGRTGEFPLTVPTRVLEALVNAGGFKDFANKKNIIIMRGTDMRGTQRIRFNYNE
VIKGKHLEQNIYLQPGDIILVR
>Mature_342_residues
MRTATLILLLAVVPIFAAPQDRAKSKSEGTQNSAMPPGAAPRFEAIPASVTAGQATQLTWTVEGATSVNIQPVVGSVPAS
GSAPVTPGETTTYTLTAVLPSGNVTATTTVTVALAGPGTTPPSTELPSPATTSPSSMAVPAPSAATSAMPEAPKATAPTI
DPTKMGAPRDGTTKPPAKVDDHAFILGAEDQIAISVYGSPEFSGSHMIRPDGKITLNFIGEVTATDLTPEQLSNEIKERI
KKYIVDPDVSVQVLAVRSKKYFIQGEVGRTGEFPLTVPTRVLEALVNAGGFKDFANKKNIIIMRGTDMRGTQRIRFNYNE
VIKGKHLEQNIYLQPGDIILVR

Specific function: Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=190, Percent_Identity=27.8947368421053, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787218, Length=176, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 35942; Mature: 35942

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTATLILLLAVVPIFAAPQDRAKSKSEGTQNSAMPPGAAPRFEAIPASVTAGQATQLTW
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TVEGATSVNIQPVVGSVPASGSAPVTPGETTTYTLTAVLPSGNVTATTTVTVALAGPGTT
EECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCCC
PPSTELPSPATTSPSSMAVPAPSAATSAMPEAPKATAPTIDPTKMGAPRDGTTKPPAKVD
CCCCCCCCCCCCCCCCEECCCCCHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
DHAFILGAEDQIAISVYGSPEFSGSHMIRPDGKITLNFIGEVTATDLTPEQLSNEIKERI
CCEEEEECCCEEEEEEECCCCCCCCEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHHH
KKYIVDPDVSVQVLAVRSKKYFIQGEVGRTGEFPLTVPTRVLEALVNAGGFKDFANKKNI
HHHCCCCCCCEEEEEEECCEEEEEECCCCCCCCCEECHHHHHHHHHCCCCCHHHCCCCCE
IIMRGTDMRGTQRIRFNYNEVIKGKHLEQNIYLQPGDIILVR
EEEECCCCCCCEEEEECHHHHHCCCCCCCEEEECCCCEEEEC
>Mature Secondary Structure
MRTATLILLLAVVPIFAAPQDRAKSKSEGTQNSAMPPGAAPRFEAIPASVTAGQATQLTW
CCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
TVEGATSVNIQPVVGSVPASGSAPVTPGETTTYTLTAVLPSGNVTATTTVTVALAGPGTT
EECCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEEECCCCC
PPSTELPSPATTSPSSMAVPAPSAATSAMPEAPKATAPTIDPTKMGAPRDGTTKPPAKVD
CCCCCCCCCCCCCCCCEECCCCCHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
DHAFILGAEDQIAISVYGSPEFSGSHMIRPDGKITLNFIGEVTATDLTPEQLSNEIKERI
CCEEEEECCCEEEEEEECCCCCCCCEEECCCCCEEEEEECCEEECCCCHHHHHHHHHHHH
KKYIVDPDVSVQVLAVRSKKYFIQGEVGRTGEFPLTVPTRVLEALVNAGGFKDFANKKNI
HHHCCCCCCCEEEEEEECCEEEEEECCCCCCCCCEECHHHHHHHHHCCCCCHHHCCCCCE
IIMRGTDMRGTQRIRFNYNEVIKGKHLEQNIYLQPGDIILVR
EEEECCCCCCCEEEEECHHHHHCCCCCCCEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]