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The map label for this gene is yuxL [H]

Identifier: 116620656

GI number: 116620656

Start: 1885285

End: 1887303

Strand: Reverse

Name: yuxL [H]

Synonym: Acid_1536

Alternate gene names: 116620656

Gene position: 1887303-1885285 (Counterclockwise)

Preceding gene: 116620669

Following gene: 116620655

Centisome position: 18.94

GC content: 61.27

Gene sequence:

>2019_bases
ATGCGGCGCCTATCGCTCCTGCTCGCTCTCTGCATCTGCGCGTTCGCGCAGAAAAAACCGTTCGACGTCAACGCCCTGTT
GGAATTGAAACGGATCGCGGATCCACAGATCTCGCCCGATGGAAAATGGGTCGCGTTCCAGGTGCAGACCGTGGACGTGC
CGGGCAACAAGAAACCCGCGCAGATCTGGATTGTGCCGTTGAACGGGGGCACGCCGCAGCAGATCACGCACGATGGGGAA
GCCAACCAGCGGCCTCGCTGGTCGCCGGATTCCAAGCGCATTGCCTACGTCAGCGACCGCGGCGGCTCGTCGCAGATCTG
GATGATGGACCCGGACGGCGGCAACGCCAAACAGGTCACGGATGTGGTCACCGAGGCGGATGGGCACGTGCTCTCGGGAG
ACGGCAAGAACGTAGTCTTCACCAGTGAAGTCTTCCCGGAATGCGGCGCCGACAATGCCTGCAACCAGAAGCTGATTGAC
GCGGAGAAGGCCAGCAAAACGAAGCCGCGGATTTACACCGAACTGCTCTACCGGCATTGGACCCGGTGGCAATCGAAGCG
GCGCATGCACATTCTGGTAGCACCGATCGCCGGCGGTCCGGTGAGAGATCTGACGCCCGGGCCGCGCGACGTGCCGCCGT
TTTCGCTGGGCGGCGACGATTTCGACGTTTCTCCAGATGGCCAGGAAGTCTGCTACAGCATGAACGCCGACGCGGTTCCC
GCGATCTCCACCAATTCCGATCTCTACGTGGTATCGATCGCGGGCGGGCAATCCAAGCGAATCACAATCACTCCGGGCAG
CGACACCGGCCCGCGCTACTCGCCGGACGGGAAGTACATTGCGTGGCGCTCGCAGTTGCGCGGTGGCTATGAGAGTGACC
GTTTTCGCCTGATGACGCTGGAGCGAAGTTCGGGAAAGGTCAACAATCTTACCGAGAGTCTGGATCGCTGGGTCAACAGC
TTCACGTGGGCGCCGGATTCCGCGAGCCTCTTTTTCACTACCACCGATCGCGGCCGCCAGGCGATCCAAGTAATTCCACT
CTCCGGCGGCGCGATCAAGATTGCGGCAAGCGGGGACAACGAGCTCGACGACATGCAACTGACGCGCAACGGGCGCACGA
TGGTCTACACCCAGCAATCGGGCGTCGCGCCCGTGGAGATTTATCGCGCGGCCTCCACCGGGGGAGCGCCCGTGGCGTTG
ACGCACTTGAACGATCAGACGCTGAACGATTATCAACTGACGCCGCTCGAGGAGTTTTGGGTGGACGGGGCGGCCGGCGC
CAAGGTCCAGAGCTTCGTGGTCAAGCCGCCGAATTTTGACCGCACCAAAAAATATCCGGTCCTGATGCTGCTTCACGGCG
GCCCGCAGGGATTCTGGGGCCACGCATGGACTTACCGTTGGAATGCGCAGGTCTTCGCGGCGGCCGGGTACGTGGTGGTG
ATGCCCAATCCCCGCGGGTCCACGGGGTACGGCCAGAAGTTCATCGACGAGATCAACGATGACTGGGGCGGGCGCGCCTT
CGACGACGTGATGGCAGTGGCCGATCACATCGTGAGCGACATTCCGTACGCTGATGGCAGCAAGATGACCGCGGCGGGCG
GGTCCTACGGCGGCTACATGGTCGATTGGATTCTGGGCCACACGCAGCGGTTCAAGGCTCTGGTCTCGCACGCGGGCGTC
TACAACCTGATCAGCGAGTTCGGCGCGACCGAAGAGCTGTGGTTCCCGCTGTGGGAGTTCGGGGGCAACCCGTGGGACCA
TCCCGAAGAGTACTCCAAATGGTCGCCAAACACGTTCGCGAAGGATTTTCACACGCCGACATTGGTGATTCACGGCGAGC
TGGATTTCCGGGTCCCGTATAATCAGGGATTGGAGCTGTTCACCGCGCTGCAGATTCAGAAGGTTCCCTCCAAGCTGTTG
GTGTTCCCCGATGAGGGGCACTGGATTCTTAAGCCGCAGAATAGCGTGGTCTGGTACAAGACGTTCATCGATTGGTTAGA
TAGCTGGGTCAAAAAATAG

Upstream 100 bases:

>100_bases
TTTGACGGCTTTTATCAAGGTAGTGGGGAAACTTTCATGTTAACATGCCTCGGAATAAGGGATTATCCTTGCATTCGTGA
ACGGGCGTTACAATCGACGT

Downstream 100 bases:

>100_bases
TGAAAGCACTCATTGGTATTCTTGTTCTCGCGGCCATCGCCTTGGCTGCGCTTTTTACGATGTCTTCCAGTACGGCTTTG
GCGATTGCGCCCGAGGTCAA

Product: peptidase S9 prolyl oligopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MRRLSLLLALCICAFAQKKPFDVNALLELKRIADPQISPDGKWVAFQVQTVDVPGNKKPAQIWIVPLNGGTPQQITHDGE
ANQRPRWSPDSKRIAYVSDRGGSSQIWMMDPDGGNAKQVTDVVTEADGHVLSGDGKNVVFTSEVFPECGADNACNQKLID
AEKASKTKPRIYTELLYRHWTRWQSKRRMHILVAPIAGGPVRDLTPGPRDVPPFSLGGDDFDVSPDGQEVCYSMNADAVP
AISTNSDLYVVSIAGGQSKRITITPGSDTGPRYSPDGKYIAWRSQLRGGYESDRFRLMTLERSSGKVNNLTESLDRWVNS
FTWAPDSASLFFTTTDRGRQAIQVIPLSGGAIKIAASGDNELDDMQLTRNGRTMVYTQQSGVAPVEIYRAASTGGAPVAL
THLNDQTLNDYQLTPLEEFWVDGAAGAKVQSFVVKPPNFDRTKKYPVLMLLHGGPQGFWGHAWTYRWNAQVFAAAGYVVV
MPNPRGSTGYGQKFIDEINDDWGGRAFDDVMAVADHIVSDIPYADGSKMTAAGGSYGGYMVDWILGHTQRFKALVSHAGV
YNLISEFGATEELWFPLWEFGGNPWDHPEEYSKWSPNTFAKDFHTPTLVIHGELDFRVPYNQGLELFTALQIQKVPSKLL
VFPDEGHWILKPQNSVVWYKTFIDWLDSWVKK

Sequences:

>Translated_672_residues
MRRLSLLLALCICAFAQKKPFDVNALLELKRIADPQISPDGKWVAFQVQTVDVPGNKKPAQIWIVPLNGGTPQQITHDGE
ANQRPRWSPDSKRIAYVSDRGGSSQIWMMDPDGGNAKQVTDVVTEADGHVLSGDGKNVVFTSEVFPECGADNACNQKLID
AEKASKTKPRIYTELLYRHWTRWQSKRRMHILVAPIAGGPVRDLTPGPRDVPPFSLGGDDFDVSPDGQEVCYSMNADAVP
AISTNSDLYVVSIAGGQSKRITITPGSDTGPRYSPDGKYIAWRSQLRGGYESDRFRLMTLERSSGKVNNLTESLDRWVNS
FTWAPDSASLFFTTTDRGRQAIQVIPLSGGAIKIAASGDNELDDMQLTRNGRTMVYTQQSGVAPVEIYRAASTGGAPVAL
THLNDQTLNDYQLTPLEEFWVDGAAGAKVQSFVVKPPNFDRTKKYPVLMLLHGGPQGFWGHAWTYRWNAQVFAAAGYVVV
MPNPRGSTGYGQKFIDEINDDWGGRAFDDVMAVADHIVSDIPYADGSKMTAAGGSYGGYMVDWILGHTQRFKALVSHAGV
YNLISEFGATEELWFPLWEFGGNPWDHPEEYSKWSPNTFAKDFHTPTLVIHGELDFRVPYNQGLELFTALQIQKVPSKLL
VFPDEGHWILKPQNSVVWYKTFIDWLDSWVKK
>Mature_672_residues
MRRLSLLLALCICAFAQKKPFDVNALLELKRIADPQISPDGKWVAFQVQTVDVPGNKKPAQIWIVPLNGGTPQQITHDGE
ANQRPRWSPDSKRIAYVSDRGGSSQIWMMDPDGGNAKQVTDVVTEADGHVLSGDGKNVVFTSEVFPECGADNACNQKLID
AEKASKTKPRIYTELLYRHWTRWQSKRRMHILVAPIAGGPVRDLTPGPRDVPPFSLGGDDFDVSPDGQEVCYSMNADAVP
AISTNSDLYVVSIAGGQSKRITITPGSDTGPRYSPDGKYIAWRSQLRGGYESDRFRLMTLERSSGKVNNLTESLDRWVNS
FTWAPDSASLFFTTTDRGRQAIQVIPLSGGAIKIAASGDNELDDMQLTRNGRTMVYTQQSGVAPVEIYRAASTGGAPVAL
THLNDQTLNDYQLTPLEEFWVDGAAGAKVQSFVVKPPNFDRTKKYPVLMLLHGGPQGFWGHAWTYRWNAQVFAAAGYVVV
MPNPRGSTGYGQKFIDEINDDWGGRAFDDVMAVADHIVSDIPYADGSKMTAAGGSYGGYMVDWILGHTQRFKALVSHAGV
YNLISEFGATEELWFPLWEFGGNPWDHPEEYSKWSPNTFAKDFHTPTLVIHGELDFRVPYNQGLELFTALQIQKVPSKLL
VFPDEGHWILKPQNSVVWYKTFIDWLDSWVKK

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=458, Percent_Identity=23.7991266375546, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI37577089, Length=307, Percent_Identity=25.7328990228013, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI18450280, Length=307, Percent_Identity=25.7328990228013, Blast_Score=76, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144537, Length=220, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25144540, Length=220, Percent_Identity=31.8181818181818, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25149159, Length=235, Percent_Identity=26.3829787234043, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17552908, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582257, Length=257, Percent_Identity=25.6809338521401, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551969, Length=255, Percent_Identity=25.0980392156863, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI45550825, Length=255, Percent_Identity=25.0980392156863, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553511, Length=255, Percent_Identity=25.0980392156863, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 74633; Mature: 74633

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLSLLLALCICAFAQKKPFDVNALLELKRIADPQISPDGKWVAFQVQTVDVPGNKKPA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCC
QIWIVPLNGGTPQQITHDGEANQRPRWSPDSKRIAYVSDRGGSSQIWMMDPDGGNAKQVT
EEEEEECCCCCCCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCHHHHH
DVVTEADGHVLSGDGKNVVFTSEVFPECGADNACNQKLIDAEKASKTKPRIYTELLYRHW
HHHHCCCCCEECCCCCEEEEEHHHCCCCCCCCCCCCHHHCHHHHCCCCCHHHHHHHHHHH
TRWQSKRRMHILVAPIAGGPVRDLTPGPRDVPPFSLGGDDFDVSPDGQEVCYSMNADAVP
HHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCC
AISTNSDLYVVSIAGGQSKRITITPGSDTGPRYSPDGKYIAWRSQLRGGYESDRFRLMTL
EEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCEEEEEE
ERSSGKVNNLTESLDRWVNSFTWAPDSASLFFTTTDRGRQAIQVIPLSGGAIKIAASGDN
ECCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEECCCC
ELDDMQLTRNGRTMVYTQQSGVAPVEIYRAASTGGAPVALTHLNDQTLNDYQLTPLEEFW
CCCCEEEECCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEECCCHHHHH
VDGAAGAKVQSFVVKPPNFDRTKKYPVLMLLHGGPQGFWGHAWTYRWNAQVFAAAGYVVV
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCEEEEECCEEEE
MPNPRGSTGYGQKFIDEINDDWGGRAFDDVMAVADHIVSDIPYADGSKMTAAGGSYGGYM
ECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
VDWILGHTQRFKALVSHAGVYNLISEFGATEELWFPLWEFGGNPWDHPEEYSKWSPNTFA
EEHHHCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHH
KDFHTPTLVIHGELDFRVPYNQGLELFTALQIQKVPSKLLVFPDEGHWILKPQNSVVWYK
HHCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEECCCCCEEEHH
TFIDWLDSWVKK
HHHHHHHHHHCC
>Mature Secondary Structure
MRRLSLLLALCICAFAQKKPFDVNALLELKRIADPQISPDGKWVAFQVQTVDVPGNKKPA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCCC
QIWIVPLNGGTPQQITHDGEANQRPRWSPDSKRIAYVSDRGGSSQIWMMDPDGGNAKQVT
EEEEEECCCCCCCCEECCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCHHHHH
DVVTEADGHVLSGDGKNVVFTSEVFPECGADNACNQKLIDAEKASKTKPRIYTELLYRHW
HHHHCCCCCEECCCCCEEEEEHHHCCCCCCCCCCCCHHHCHHHHCCCCCHHHHHHHHHHH
TRWQSKRRMHILVAPIAGGPVRDLTPGPRDVPPFSLGGDDFDVSPDGQEVCYSMNADAVP
HHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCC
AISTNSDLYVVSIAGGQSKRITITPGSDTGPRYSPDGKYIAWRSQLRGGYESDRFRLMTL
EEECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCEEEEEE
ERSSGKVNNLTESLDRWVNSFTWAPDSASLFFTTTDRGRQAIQVIPLSGGAIKIAASGDN
ECCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEECCCC
ELDDMQLTRNGRTMVYTQQSGVAPVEIYRAASTGGAPVALTHLNDQTLNDYQLTPLEEFW
CCCCEEEECCCCEEEEECCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCEECCCHHHHH
VDGAAGAKVQSFVVKPPNFDRTKKYPVLMLLHGGPQGFWGHAWTYRWNAQVFAAAGYVVV
CCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCEEEEECCEEEE
MPNPRGSTGYGQKFIDEINDDWGGRAFDDVMAVADHIVSDIPYADGSKMTAAGGSYGGYM
ECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
VDWILGHTQRFKALVSHAGVYNLISEFGATEELWFPLWEFGGNPWDHPEEYSKWSPNTFA
EEHHHCCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHH
KDFHTPTLVIHGELDFRVPYNQGLELFTALQIQKVPSKLLVFPDEGHWILKPQNSVVWYK
HHCCCCEEEEEECEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEECCCCCEEEHH
TFIDWLDSWVKK
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]