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The map label for this gene is iolE [H]

Identifier: 116620605

GI number: 116620605

Start: 1821295

End: 1822227

Strand: Direct

Name: iolE [H]

Synonym: Acid_1484

Alternate gene names: 116620605

Gene position: 1821295-1822227 (Clockwise)

Preceding gene: 116620604

Following gene: 116620606

Centisome position: 18.28

GC content: 63.77

Gene sequence:

>933_bases
ATGGCAAAACTACTGGTCGGCAACGCCCCTTGTTCCTGGGGCAGGTTGGAATTCGATGAAGCGAAGGGAGAGCAAATCCC
GTTTAACCGCATGCTCGACGAGCTTGCTGAAACCGGCTATACGGGAACCGAGCTGGGTGATTGGGGCTATATGCCCACGG
ACCCGGCGGGGCTGAAGGGGGAGCTCGACAAGCGCGGGCTGATGATGCTGGGCGCGTTTGTACCGGTTGCATTGAAGGAC
CCCTCGGCGCATGAGGTGGGGATTGCGAATGCGGTCAAGACGGCGCGATTGCTGGCGGCCGTCGGGGGCAATCCCGCGCC
CTACCTGGTGCTGGCCGATGATAATGGCACGGTGTTGGACCGGACGCGGATGGCGGGCCGGGTGACCGAGCAACTGGGGC
TGACACCTTCGGAGTGGAGAATTTTCGCGCGCGGCGCCGATGGCGTGGCGCGGGCCGTGCACGAGGAAACCGGACTGCGA
ACGGTCTTCCACCATCATTGCGCGGGCTATGTGGAGACGCCGGACGAGATCGCGACGCTGCTGGCGCTGACGGACCCGAA
GCGGCTTGGCCTGGTGTTCGATACCGGCCACTATTGCTACGGAGCGGGCGGCAGGGATTGCGACGTGGCGGCGGCGCTGG
AGCGTTTCGGCGACCGGGTCTGGTACATACACTGCAAGGACTGCGACCCGGAAGTGGCACAGCGGGCACGGTGGAAGCAG
TGGGATTATTTCACCGCACTGCGCAATGGCGTGTTCTGCGAACTGGGCAAGGGCTGCGTGGATTTTCCGGGGCTGCTGCG
CAGTTTGGCGGGCCGCGCATACGAGGGTTACGTGCTGGTGGAGCAGGATGTGCTGCCCGGGATGGGCAGTCCGAAAGAGA
GCGCGCGTCGAAATCGCGACTACCTGCGGTCGATCGAATCGAATTTTGCCTGA

Upstream 100 bases:

>100_bases
TGACGGAAAGCCCCTGGCAGGCCGGCAATGCGCCTGTAGCGCGGCGGCCTGCCCGAATCAACCGCGAAGTCCGGTCAAAC
GACTTTCCGAGAGGAAGCAC

Downstream 100 bases:

>100_bases
GAGGAAAACGTGAGCACAAGACAGTTGAATGTAGGAATCATCGGCGCGGGACGGATCGGAAAAGTGCATGCGGAAACGCT
GGCCTTCCGGTTGCCGGAGG

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAKLLVGNAPCSWGRLEFDEAKGEQIPFNRMLDELAETGYTGTELGDWGYMPTDPAGLKGELDKRGLMMLGAFVPVALKD
PSAHEVGIANAVKTARLLAAVGGNPAPYLVLADDNGTVLDRTRMAGRVTEQLGLTPSEWRIFARGADGVARAVHEETGLR
TVFHHHCAGYVETPDEIATLLALTDPKRLGLVFDTGHYCYGAGGRDCDVAAALERFGDRVWYIHCKDCDPEVAQRARWKQ
WDYFTALRNGVFCELGKGCVDFPGLLRSLAGRAYEGYVLVEQDVLPGMGSPKESARRNRDYLRSIESNFA

Sequences:

>Translated_310_residues
MAKLLVGNAPCSWGRLEFDEAKGEQIPFNRMLDELAETGYTGTELGDWGYMPTDPAGLKGELDKRGLMMLGAFVPVALKD
PSAHEVGIANAVKTARLLAAVGGNPAPYLVLADDNGTVLDRTRMAGRVTEQLGLTPSEWRIFARGADGVARAVHEETGLR
TVFHHHCAGYVETPDEIATLLALTDPKRLGLVFDTGHYCYGAGGRDCDVAAALERFGDRVWYIHCKDCDPEVAQRARWKQ
WDYFTALRNGVFCELGKGCVDFPGLLRSLAGRAYEGYVLVEQDVLPGMGSPKESARRNRDYLRSIESNFA
>Mature_309_residues
AKLLVGNAPCSWGRLEFDEAKGEQIPFNRMLDELAETGYTGTELGDWGYMPTDPAGLKGELDKRGLMMLGAFVPVALKDP
SAHEVGIANAVKTARLLAAVGGNPAPYLVLADDNGTVLDRTRMAGRVTEQLGLTPSEWRIFARGADGVARAVHEETGLRT
VFHHHCAGYVETPDEIATLLALTDPKRLGLVFDTGHYCYGAGGRDCDVAAALERFGDRVWYIHCKDCDPEVAQRARWKQW
DYFTALRNGVFCELGKGCVDFPGLLRSLAGRAYEGYVLVEQDVLPGMGSPKESARRNRDYLRSIESNFA

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 33987; Mature: 33856

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLLVGNAPCSWGRLEFDEAKGEQIPFNRMLDELAETGYTGTELGDWGYMPTDPAGLKG
CCCEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ELDKRGLMMLGAFVPVALKDPSAHEVGIANAVKTARLLAAVGGNPAPYLVLADDNGTVLD
CCCCCHHEEHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEH
RTRMAGRVTEQLGLTPSEWRIFARGADGVARAVHEETGLRTVFHHHCAGYVETPDEIATL
HHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
LALTDPKRLGLVFDTGHYCYGAGGRDCDVAAALERFGDRVWYIHCKDCDPEVAQRARWKQ
HHCCCCCCEEEEEECCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHCCCC
WDYFTALRNGVFCELGKGCVDFPGLLRSLAGRAYEGYVLVEQDVLPGMGSPKESARRNRD
HHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
YLRSIESNFA
HHHHHHHCCC
>Mature Secondary Structure 
AKLLVGNAPCSWGRLEFDEAKGEQIPFNRMLDELAETGYTGTELGDWGYMPTDPAGLKG
CCEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
ELDKRGLMMLGAFVPVALKDPSAHEVGIANAVKTARLLAAVGGNPAPYLVLADDNGTVLD
CCCCCHHEEHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEH
RTRMAGRVTEQLGLTPSEWRIFARGADGVARAVHEETGLRTVFHHHCAGYVETPDEIATL
HHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHH
LALTDPKRLGLVFDTGHYCYGAGGRDCDVAAALERFGDRVWYIHCKDCDPEVAQRARWKQ
HHCCCCCCEEEEEECCCEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHCCCC
WDYFTALRNGVFCELGKGCVDFPGLLRSLAGRAYEGYVLVEQDVLPGMGSPKESARRNRD
HHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
YLRSIESNFA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA