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The map label for this gene is atoS [H]

Identifier: 116620564

GI number: 116620564

Start: 1772686

End: 1773969

Strand: Reverse

Name: atoS [H]

Synonym: Acid_1442

Alternate gene names: 116620564

Gene position: 1773969-1772686 (Counterclockwise)

Preceding gene: 116620577

Following gene: 116620563

Centisome position: 17.8

GC content: 65.26

Gene sequence:

>1284_bases
ATGCGCCGGGCGCAAAATCGAGACTGGCTACTTCCGGGAAGCGCGGAGCGGGACGAGGGCTTTCGACTCGAGATGCTCTC
GGTGAGCTATCAGGGCGTGCGCGCGATCGCGGCGGTGGAGGCCGCGGCCGCGATCGGCGCGCTCGCCGGAGTGATGCCGG
GCGCGACCGCGCTCAGCCTGGTGATCCTCGGTGCGGCGACTTTTGGTCTCGCCAGCCTGAGCGCGTCCTATCCATGGGGC
CGCATGCTGGCAGGCGTTTCGGCGGTGGCAGGAGCGGTAATCGCAGTGCGATCGATGCTCACCGGCGGGGTGGCGGACTA
TGCGCTGGGAGTGGCTACGCTGCTGTTGCTGGTCGCGGTTACGGCGGTGCCGATGCGTCCGCTCGAGTGCCTGCTGATGG
GCGCCGTGCTGGTGGCCGCCGGCCTGGAGTGCGGACACCTGTGGTTTTTCGCGATGCTCACTCTGGGCGCGGTATTGATT
GGGGGCACGCAATATGGGCACCGGCGCATTCAATACGCTTCGTATGTAGATGCGCTGCACAACTCATCGGAGTTGCGGGA
ATACCAGTCGCAGGCGATGAGAGCGGAGAGCTCCGCGACGATGGTGAGGCTGACGGCGGCGCTGGCGCACGAGTTGAGTT
CACCCATCGGCGCATTGACTAGTGGCATCGAGACGCTGGTCGCGGTCTGTGCGCGGCAGGCACAGTCGCCGCCCGAGGCG
CAGCAGCGGCTGCTCGGCATGCAGGCGGACCTGCGGCGGTCGCTGCAGGATTCGCTCGACCGGCTGCGAAAGACGGTCAA
CCGGATCCAACGGCTGACCAACCTCGATGAAGCCGTGACCCAGCAGGCCAATTTGAACGAGCTGGTGAATGAGGCTGTGA
GCCTGGTGAAGGCGCAGGGTCCGGCGGGGACGCGGTTCGACCTGGACCTGCACCCCGTGCCGGATGTGACCTGCCGGCCG
CAGCGGCTGATGTCGGTGCTGTGCAGCCTGCTGACCAACTCGATTCAGGCGCTGACCGGGGAGGGGCGCATCGCGATTTC
GACACAACAGCGCGAGAGTGTGTTGGAGGTGCGGATCGAGGACAACGGGTGCGGGATCCCGGCCGAGCAATTGGTTCGCA
TTTTCGATCCGCGTTTCGAGGTGACCGGCGGCCGGGTATCGACCGGAAACTGGAGCCTGTTCATGTCGCGGCAATACATG
AAAGAGCACGGCGGCGACATCCGCATTCAGAGTAAGGAAGGAAAAGGTACAACCGTATGCCTGACACTGCCCGCGGCATC
CTAA

Upstream 100 bases:

>100_bases
CAGGGCGAACATCGTATACGCCACGCCAGAAGAGCCGTATAGTCCGCATAAAGGGTCTAACGATACTATCACGGTCCACG
CGCGATATATTGGTGAAACT

Downstream 100 bases:

>100_bases
TGGTATTTCTGCTGGCCCCGGCGCTTTTGCCGGCGGCGCAGTCCGAGTGGAAGAATGTCCCGAGGGTGGTCGCGGTGGGC
GATGTCCACGGCGATTACAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRRAQNRDWLLPGSAERDEGFRLEMLSVSYQGVRAIAAVEAAAAIGALAGVMPGATALSLVILGAATFGLASLSASYPWG
RMLAGVSAVAGAVIAVRSMLTGGVADYALGVATLLLLVAVTAVPMRPLECLLMGAVLVAAGLECGHLWFFAMLTLGAVLI
GGTQYGHRRIQYASYVDALHNSSELREYQSQAMRAESSATMVRLTAALAHELSSPIGALTSGIETLVAVCARQAQSPPEA
QQRLLGMQADLRRSLQDSLDRLRKTVNRIQRLTNLDEAVTQQANLNELVNEAVSLVKAQGPAGTRFDLDLHPVPDVTCRP
QRLMSVLCSLLTNSIQALTGEGRIAISTQQRESVLEVRIEDNGCGIPAEQLVRIFDPRFEVTGGRVSTGNWSLFMSRQYM
KEHGGDIRIQSKEGKGTTVCLTLPAAS

Sequences:

>Translated_427_residues
MRRAQNRDWLLPGSAERDEGFRLEMLSVSYQGVRAIAAVEAAAAIGALAGVMPGATALSLVILGAATFGLASLSASYPWG
RMLAGVSAVAGAVIAVRSMLTGGVADYALGVATLLLLVAVTAVPMRPLECLLMGAVLVAAGLECGHLWFFAMLTLGAVLI
GGTQYGHRRIQYASYVDALHNSSELREYQSQAMRAESSATMVRLTAALAHELSSPIGALTSGIETLVAVCARQAQSPPEA
QQRLLGMQADLRRSLQDSLDRLRKTVNRIQRLTNLDEAVTQQANLNELVNEAVSLVKAQGPAGTRFDLDLHPVPDVTCRP
QRLMSVLCSLLTNSIQALTGEGRIAISTQQRESVLEVRIEDNGCGIPAEQLVRIFDPRFEVTGGRVSTGNWSLFMSRQYM
KEHGGDIRIQSKEGKGTTVCLTLPAAS
>Mature_427_residues
MRRAQNRDWLLPGSAERDEGFRLEMLSVSYQGVRAIAAVEAAAAIGALAGVMPGATALSLVILGAATFGLASLSASYPWG
RMLAGVSAVAGAVIAVRSMLTGGVADYALGVATLLLLVAVTAVPMRPLECLLMGAVLVAAGLECGHLWFFAMLTLGAVLI
GGTQYGHRRIQYASYVDALHNSSELREYQSQAMRAESSATMVRLTAALAHELSSPIGALTSGIETLVAVCARQAQSPPEA
QQRLLGMQADLRRSLQDSLDRLRKTVNRIQRLTNLDEAVTQQANLNELVNEAVSLVKAQGPAGTRFDLDLHPVPDVTCRP
QRLMSVLCSLLTNSIQALTGEGRIAISTQQRESVLEVRIEDNGCGIPAEQLVRIFDPRFEVTGGRVSTGNWSLFMSRQYM
KEHGGDIRIQSKEGKGTTVCLTLPAAS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=31.0204081632653, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=29.7071129707113, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=274, Percent_Identity=27.7372262773723, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45583; Mature: 45583

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAQNRDWLLPGSAERDEGFRLEMLSVSYQGVRAIAAVEAAAAIGALAGVMPGATALSL
CCCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VILGAATFGLASLSASYPWGRMLAGVSAVAGAVIAVRSMLTGGVADYALGVATLLLLVAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAVPMRPLECLLMGAVLVAAGLECGHLWFFAMLTLGAVLIGGTQYGHRRIQYASYVDALH
HHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NSSELREYQSQAMRAESSATMVRLTAALAHELSSPIGALTSGIETLVAVCARQAQSPPEA
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHH
QQRLLGMQADLRRSLQDSLDRLRKTVNRIQRLTNLDEAVTQQANLNELVNEAVSLVKAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
PAGTRFDLDLHPVPDVTCRPQRLMSVLCSLLTNSIQALTGEGRIAISTQQRESVLEVRIE
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCEEEEEEC
DNGCGIPAEQLVRIFDPRFEVTGGRVSTGNWSLFMSRQYMKEHGGDIRIQSKEGKGTTVC
CCCCCCCHHHHHHHHCCCEEECCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LTLPAAS
EEECCCC
>Mature Secondary Structure
MRRAQNRDWLLPGSAERDEGFRLEMLSVSYQGVRAIAAVEAAAAIGALAGVMPGATALSL
CCCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VILGAATFGLASLSASYPWGRMLAGVSAVAGAVIAVRSMLTGGVADYALGVATLLLLVAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TAVPMRPLECLLMGAVLVAAGLECGHLWFFAMLTLGAVLIGGTQYGHRRIQYASYVDALH
HHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NSSELREYQSQAMRAESSATMVRLTAALAHELSSPIGALTSGIETLVAVCARQAQSPPEA
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHH
QQRLLGMQADLRRSLQDSLDRLRKTVNRIQRLTNLDEAVTQQANLNELVNEAVSLVKAQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
PAGTRFDLDLHPVPDVTCRPQRLMSVLCSLLTNSIQALTGEGRIAISTQQRESVLEVRIE
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHCCEEEEEEC
DNGCGIPAEQLVRIFDPRFEVTGGRVSTGNWSLFMSRQYMKEHGGDIRIQSKEGKGTTVC
CCCCCCCHHHHHHHHCCCEEECCCEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCEEE
LTLPAAS
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]