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The map label for this gene is desR [H]

Identifier: 116620395

GI number: 116620395

Start: 1570750

End: 1571352

Strand: Reverse

Name: desR [H]

Synonym: Acid_1272

Alternate gene names: 116620395

Gene position: 1571352-1570750 (Counterclockwise)

Preceding gene: 116620396

Following gene: 116620394

Centisome position: 15.77

GC content: 66.83

Gene sequence:

>603_bases
ATGATCCGCGTCCTCATCGCCGAAGATCAGGCCATGGTGCGCGGCGCGCTCGCTGCCCTGCTCACCACCGAGGGTGATTT
CGAAATCGCGGGCGACGCACCCAACGGTCGCGCCGCGCTCGATCTCGCAATCAAACTCCTGCCCGACGTTCTGCTCACCG
ATATCGAGATGCCCGAGCTGACCGGCCTGGAGCTGGCCGCCGAAATCCGGCGGCTCCATCTGCCCATCAAGGTCGTCATC
CTCACCACCTTCGCCCGTGCGGGATATTTACGCCGCGCGCTCGATGCCGGCGTCTCCGGCTACCTGCTCAAGGACGCGCC
CGCTTCCACGCTCGCCAACGCCATCCGCCGCATCCGAGCCGGCGCCCGCGTCATCGATCCTGAACTGGCGGCTGAAGCCT
GGACCGAAGCGGACCCGCTCACCGACCGCGAACGCCAGGTACTCCGCCACGCCGGCGAAGGTCGGAGCGGGGCTGAAATC
GCCGGACTCCTCAATCTCTCCGAAGGCACCGTGCGCAACTATCTCTCCGAGGCGATCAGTAAACTGGGCGCCGCCAATCG
CACCGAGGCCGCTCGCATCGCCCATCAGCGCGGCTGGCTATAG

Upstream 100 bases:

>100_bases
GCAGCGGCCTCAGCGGCATGCGCGAACGCGTGGAGGCGCTCGGCGGAATCCTCGAACGCGATGGTTCGCGTGGCACGCTG
CTGCGTATTCGGGTGCCTGT

Downstream 100 bases:

>100_bases
AATAGGCCTCCGGCCGCTTCCGGCTCTCCAGAGTGATCTGTTTTGTTGTTTGCTGGCGCACATCGGGCACCCGCGTGCTC
CTCCACCCCCCTGAGGAGCC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIRVLIAEDQAMVRGALAALLTTEGDFEIAGDAPNGRAALDLAIKLLPDVLLTDIEMPELTGLELAAEIRRLHLPIKVVI
LTTFARAGYLRRALDAGVSGYLLKDAPASTLANAIRRIRAGARVIDPELAAEAWTEADPLTDRERQVLRHAGEGRSGAEI
AGLLNLSEGTVRNYLSEAISKLGAANRTEAARIAHQRGWL

Sequences:

>Translated_200_residues
MIRVLIAEDQAMVRGALAALLTTEGDFEIAGDAPNGRAALDLAIKLLPDVLLTDIEMPELTGLELAAEIRRLHLPIKVVI
LTTFARAGYLRRALDAGVSGYLLKDAPASTLANAIRRIRAGARVIDPELAAEAWTEADPLTDRERQVLRHAGEGRSGAEI
AGLLNLSEGTVRNYLSEAISKLGAANRTEAARIAHQRGWL
>Mature_200_residues
MIRVLIAEDQAMVRGALAALLTTEGDFEIAGDAPNGRAALDLAIKLLPDVLLTDIEMPELTGLELAAEIRRLHLPIKVVI
LTTFARAGYLRRALDAGVSGYLLKDAPASTLANAIRRIRAGARVIDPELAAEAWTEADPLTDRERQVLRHAGEGRSGAEI
AGLLNLSEGTVRNYLSEAISKLGAANRTEAARIAHQRGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=32.8502415458937, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=32.5, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=29.8076923076923, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787473, Length=204, Percent_Identity=32.843137254902, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082052, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1786747, Length=188, Percent_Identity=25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788192, Length=105, Percent_Identity=34.2857142857143, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21489; Mature: 21489

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVLIAEDQAMVRGALAALLTTEGDFEIAGDAPNGRAALDLAIKLLPDVLLTDIEMPEL
CEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
TGLELAAEIRRLHLPIKVVILTTFARAGYLRRALDAGVSGYLLKDAPASTLANAIRRIRA
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
GARVIDPELAAEAWTEADPLTDRERQVLRHAGEGRSGAEIAGLLNLSEGTVRNYLSEAIS
CCEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHEEECCHHHHHHHHHHHHH
KLGAANRTEAARIAHQRGWL
HHCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MIRVLIAEDQAMVRGALAALLTTEGDFEIAGDAPNGRAALDLAIKLLPDVLLTDIEMPEL
CEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
TGLELAAEIRRLHLPIKVVILTTFARAGYLRRALDAGVSGYLLKDAPASTLANAIRRIRA
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
GARVIDPELAAEAWTEADPLTDRERQVLRHAGEGRSGAEIAGLLNLSEGTVRNYLSEAIS
CCEECCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHEEECCHHHHHHHHHHHHH
KLGAANRTEAARIAHQRGWL
HHCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]