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The map label for this gene is 116620377

Identifier: 116620377

GI number: 116620377

Start: 1551465

End: 1552784

Strand: Direct

Name: 116620377

Synonym: Acid_1254

Alternate gene names: NA

Gene position: 1551465-1552784 (Clockwise)

Preceding gene: 116620375

Following gene: 116620378

Centisome position: 15.57

GC content: 57.95

Gene sequence:

>1320_bases
TTGCCGAATAAGGACAACGTCCAAATTGCGCCTGCCGAAGGGAAACTGGGAGTTTTGATTCCCGGAATGGGCGCGGTGAC
GACGACCTTCATCGCCGGGCTCGAAGCCTTCAAGCTCGGGTTGGGGAAGCCAATCGGATCGCTCACGCAGTTGGGCACCA
TCCGCTTGGGTAAGAGGACCGAAGGGCGCAACCCCGCGATTAAAGATTTTGTTCCGCTGGCCAACATGTCGGACATCGAA
GTGGGCTGCTGGGACATTTTTGAGGACAACGCCTACGAAGCGGCCGTGAAGGCCGGTGTGCTCGAGACTTCGCTGCTCGA
CCAGGTTAAGGGACCGCTCTCGGCGATTCAGCCGATGAAAGCCGTCTTCGACCAGAACTTCGTGAAGCGGATCAAGGGCC
CGAACGTGAAGACCGGCGGCTCCAAAATGGATCACGTGGAGATGGTCATGGACGACATCCGCAAGTTCAAGGAACGGACT
GGGGTATCGCGAACCACCATGATCTGGTGCGGGTCCACCGAGGTTTATCACGAGGCGGCCCCGGTGCATGCCACGCTGAA
GGATTTCGAGTGCGGGCTGCAGAAGAACGATCCGGAGATTTCGCCGAGCCAGATCTACGCCTATGCGGCGCTCAAGAGCG
GCGTCAGCTACGCCAATGGCGCTCCGCACTTGACCACGGATATGCCGGCGCTGCAGGAACTGGCGCGCACAATGAACCTG
CCGGTGTGCGGCAAGGATTACAAGAGCGGTCAGACGTTCATGAAGACGCTGATCGCGCCTGGTTTGAAGAGCCGGCTGCT
GGGGTTAAACGGCTGGTTTTCGACCAACATCCTGGGGAATCGCGACGGGGAAGTGCTTGACGAACCGGGCAGTTTCCGGT
CAAAGGAAGTCAGCAAAAGCTCGGCGCTGGAGCACATTTTACAGGGCGAACTCTACCCCGACCTGTACAAGGAGTTTTAC
CACAAGGTGCGGATTGAGTACTATCCGCCGCGTGGGGACGCCAAGGAAGGCTGGGACAACATCGACATCTTCGGGTGGCT
GGGCTACCCGATGCAGATCAAGATTAATTTCCTGTGCCGCGATTCGATCTTGGCCGCGCCGCTGGTTTTGGATATCGTAT
TGTTCATGGACCTGGCGCAGCGCGCCGGGATGCGCGGCATCCAGGAATGGCTTTCGTTTTACTTCAAAGCGCCGATGCAT
GCTCCGGAGCTTTACCCCGAGCATGACATCTTCATCCAGCTCATGAAGCTGAAAAACACCCTGCGCTGGATGCGGGGCGA
GGACCTGATCACGCATTTGGGCCTGGAATATTACGATTAG

Upstream 100 bases:

>100_bases
GCCAGCTGTTCGTCGTCTACGACAACTGTAGTGAGGGTTGCCGTCGCGCGGTCTCGCATGGAGTTGGTATTATAGCATTT
TGGTCTTAAAGGAGAACCGT

Downstream 100 bases:

>100_bases
TAGCGGTATTGTTTGAAGACGCGGGGGCACGGAACGGAATCGGTTTCCGCGCCGTCGCGTCTTAGTGTCTGTAGTGGCAG
TCTTAGGGAGCTCCTATGAA

Product: inositol-3-phosphate synthase

Products: 1D-myo-inositol 3-phosphate

Alternate protein names: Inositol-3-Phosphate Synthase; Secreted Protein; Myo-Inositol Phosphate Synthase; InositoL-3-Phosphate Synthase

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MPNKDNVQIAPAEGKLGVLIPGMGAVTTTFIAGLEAFKLGLGKPIGSLTQLGTIRLGKRTEGRNPAIKDFVPLANMSDIE
VGCWDIFEDNAYEAAVKAGVLETSLLDQVKGPLSAIQPMKAVFDQNFVKRIKGPNVKTGGSKMDHVEMVMDDIRKFKERT
GVSRTTMIWCGSTEVYHEAAPVHATLKDFECGLQKNDPEISPSQIYAYAALKSGVSYANGAPHLTTDMPALQELARTMNL
PVCGKDYKSGQTFMKTLIAPGLKSRLLGLNGWFSTNILGNRDGEVLDEPGSFRSKEVSKSSALEHILQGELYPDLYKEFY
HKVRIEYYPPRGDAKEGWDNIDIFGWLGYPMQIKINFLCRDSILAAPLVLDIVLFMDLAQRAGMRGIQEWLSFYFKAPMH
APELYPEHDIFIQLMKLKNTLRWMRGEDLITHLGLEYYD

Sequences:

>Translated_439_residues
MPNKDNVQIAPAEGKLGVLIPGMGAVTTTFIAGLEAFKLGLGKPIGSLTQLGTIRLGKRTEGRNPAIKDFVPLANMSDIE
VGCWDIFEDNAYEAAVKAGVLETSLLDQVKGPLSAIQPMKAVFDQNFVKRIKGPNVKTGGSKMDHVEMVMDDIRKFKERT
GVSRTTMIWCGSTEVYHEAAPVHATLKDFECGLQKNDPEISPSQIYAYAALKSGVSYANGAPHLTTDMPALQELARTMNL
PVCGKDYKSGQTFMKTLIAPGLKSRLLGLNGWFSTNILGNRDGEVLDEPGSFRSKEVSKSSALEHILQGELYPDLYKEFY
HKVRIEYYPPRGDAKEGWDNIDIFGWLGYPMQIKINFLCRDSILAAPLVLDIVLFMDLAQRAGMRGIQEWLSFYFKAPMH
APELYPEHDIFIQLMKLKNTLRWMRGEDLITHLGLEYYD
>Mature_438_residues
PNKDNVQIAPAEGKLGVLIPGMGAVTTTFIAGLEAFKLGLGKPIGSLTQLGTIRLGKRTEGRNPAIKDFVPLANMSDIEV
GCWDIFEDNAYEAAVKAGVLETSLLDQVKGPLSAIQPMKAVFDQNFVKRIKGPNVKTGGSKMDHVEMVMDDIRKFKERTG
VSRTTMIWCGSTEVYHEAAPVHATLKDFECGLQKNDPEISPSQIYAYAALKSGVSYANGAPHLTTDMPALQELARTMNLP
VCGKDYKSGQTFMKTLIAPGLKSRLLGLNGWFSTNILGNRDGEVLDEPGSFRSKEVSKSSALEHILQGELYPDLYKEFYH
KVRIEYYPPRGDAKEGWDNIDIFGWLGYPMQIKINFLCRDSILAAPLVLDIVLFMDLAQRAGMRGIQEWLSFYFKAPMHA
PELYPEHDIFIQLMKLKNTLRWMRGEDLITHLGLEYYD

Specific function: Unknown

COG id: COG1260

COG function: function code I; Myo-inositol-1-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7705558, Length=457, Percent_Identity=32.1663019693654, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI283135176, Length=415, Percent_Identity=32.7710843373494, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI283135178, Length=362, Percent_Identity=32.3204419889503, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25147617, Length=412, Percent_Identity=31.3106796116505, Blast_Score=194, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322308, Length=457, Percent_Identity=31.0722100656455, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI17137626, Length=455, Percent_Identity=31.6483516483516, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.5.1.4

Molecular weight: Translated: 48978; Mature: 48847

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKDNVQIAPAEGKLGVLIPGMGAVTTTFIAGLEAFKLGLGKPIGSLTQLGTIRLGKRT
CCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEECCCC
EGRNPAIKDFVPLANMSDIEVGCWDIFEDNAYEAAVKAGVLETSLLDQVKGPLSAIQPMK
CCCCCCHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AVFDQNFVKRIKGPNVKTGGSKMDHVEMVMDDIRKFKERTGVSRTTMIWCGSTEVYHEAA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCC
PVHATLKDFECGLQKNDPEISPSQIYAYAALKSGVSYANGAPHLTTDMPALQELARTMNL
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
PVCGKDYKSGQTFMKTLIAPGLKSRLLGLNGWFSTNILGNRDGEVLDEPGSFRSKEVSKS
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
SALEHILQGELYPDLYKEFYHKVRIEYYPPRGDAKEGWDNIDIFGWLGYPMQIKINFLCR
HHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEEC
DSILAAPLVLDIVLFMDLAQRAGMRGIQEWLSFYFKAPMHAPELYPEHDIFIQLMKLKNT
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LRWMRGEDLITHLGLEYYD
HHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure 
PNKDNVQIAPAEGKLGVLIPGMGAVTTTFIAGLEAFKLGLGKPIGSLTQLGTIRLGKRT
CCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCEEEECCCC
EGRNPAIKDFVPLANMSDIEVGCWDIFEDNAYEAAVKAGVLETSLLDQVKGPLSAIQPMK
CCCCCCHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
AVFDQNFVKRIKGPNVKTGGSKMDHVEMVMDDIRKFKERTGVSRTTMIWCGSTEVYHEAA
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCC
PVHATLKDFECGLQKNDPEISPSQIYAYAALKSGVSYANGAPHLTTDMPALQELARTMNL
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
PVCGKDYKSGQTFMKTLIAPGLKSRLLGLNGWFSTNILGNRDGEVLDEPGSFRSKEVSKS
CCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHH
SALEHILQGELYPDLYKEFYHKVRIEYYPPRGDAKEGWDNIDIFGWLGYPMQIKINFLCR
HHHHHHHCCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEEC
DSILAAPLVLDIVLFMDLAQRAGMRGIQEWLSFYFKAPMHAPELYPEHDIFIQLMKLKNT
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LRWMRGEDLITHLGLEYYD
HHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glucose 6-phosphate

Specific reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA