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The map label for this gene is steT [H]

Identifier: 116620368

GI number: 116620368

Start: 1542160

End: 1543668

Strand: Direct

Name: steT [H]

Synonym: Acid_1245

Alternate gene names: 116620368

Gene position: 1542160-1543668 (Clockwise)

Preceding gene: 116620367

Following gene: 116620369

Centisome position: 15.47

GC content: 62.69

Gene sequence:

>1509_bases
ATGGTGTATCCTGCGCAGAGCCCTTCCATGACCCAACCAACCCTTCAGAAAGACACCGGATTTGTACGCGGCCTCAACCT
GTTCGATTCCACTATGGTGGTGATCGGCGTGATGATCGGGTCGGGAATATTTATCGTCTCGGCCGACATGTCGCGGTTGA
TCAATAGTCCCGGCTGGATGCTGATGGCGTGGGTGATCACGGGGGTGCTTACGCTGACGGCGGCGCTATCGTATGGAGAG
CTTGCCTCGATGCTGCCGCACGCGGGCGGGATGTACGTATATCTGCGCGAGGCGTTTTCGCCGTTGTGGGGATTCCTTTA
CGGGTGGACATTTTTCACGGTGATCCAGACCGGGACGATCGCGGCGGTGGCGGTGGCCTTCGCGCGATTCTCCTCGATCA
TTTTTCCGGCCATCGGGGAGAGCCGTTACCTGATTCCGCCGGTGCACATTACCGAGAGCTACGCGCTTTCGCTTTCGACG
GCGCAGCTGGTGGCGATCGCGATCATCGCGCTGTTGACGTGGACGAACACGCGCGGGCTGGAATACGGCAAGATCGTGCA
GAACCTGTTCACGTCGGCGAAAACGGTGGCCCTGGCGGCGCTGATTCTGGCCGGCATTTTCCTGGGCTGGAACTCCACCG
CGGTGCACGCGAATTTCACCGACATGTTCCGGCTGGGCAGCTTCGACGCCTCGCTCGGAGTGCAGGCCGCCAGCTTCTAC
GGGCTGATTGTGGCGCTGTGCGTGGCGCAATCAGGCTCGATGTTCTCGGCGGATTCGTGGCACGACATCACGATCATCGC
CGGGGAAGTGCGCAACCCATCGCGCAATCTGCCGCTGGCGATGGCGTTCGGATGCTCGGCGGTAATCGGCCTGTACATCC
TGGCGAACGCGGCGTACCTGGTGGTGCTGCCGCTGCCGGCGATACAGAACGCGCCAAGCGATCGCGTGGCGACGGCCATG
CTGCAGGCGATCTTTCCCGGGTACGGTCCAACGATCATGGCGATCGCGATCATGATCTCCACGTTCGGGTGCGTGAACAG
CCTGGTGCTGGCGGGTGCGCGCGCCTATTACGCGATGGCCAAGGACGGTCTCTTCTTTAAGCAGGCGGGCGTGCTCAATG
AGAATCGCGTGCCCGGGTGGTCGCTGGTGGTTCAGGGATTGTGGGCCGTGATGCTGGTGCTGCCGCGCACCTACAACGTG
GCGACCAGGCAGTACGGCAACCTCTACAGCAACCTGCTGGATTACGTGATTTCGGCGGCGCTGCTGTTCTACATCCTGAC
CATCGCGGGCGTGTTTCAACTGCGGCGCAAACGGCCCGATATGGCGCGGCCGTACAAGGTGACGGGCTACCCGGTGGTGC
CGGCGGTCTTCATCATCGGCGCGGCGATTGTGCTGTATATGTTGTTCGCCTACCGGCCGGCGACCACGTGGCCCGGCCTC
GTGATCGTGGTCATCGGTGCGGTGGTGTACGCGGGTGTAGGACGCGGCGCGGCGGCGCGGGCGGCATAG

Upstream 100 bases:

>100_bases
GCAGCCTGTATTTATCGCTGATGGACCGGATGGGCGTGAAGCTGGATCAGTTCGGGGACGCCAACACGCGGCTGGAGACT
TTGTAGAGGAAAGGCCGCAA

Downstream 100 bases:

>100_bases
GAAAAAGCGGAGGATCAGCTGCCGCGGATTTGTTAGGGCGAAAACCCGTGCGCGTTATAATGATGAGCGTGGAGAAAACG
GTCAGAGTGTTCACCAGCTT

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MVYPAQSPSMTQPTLQKDTGFVRGLNLFDSTMVVIGVMIGSGIFIVSADMSRLINSPGWMLMAWVITGVLTLTAALSYGE
LASMLPHAGGMYVYLREAFSPLWGFLYGWTFFTVIQTGTIAAVAVAFARFSSIIFPAIGESRYLIPPVHITESYALSLST
AQLVAIAIIALLTWTNTRGLEYGKIVQNLFTSAKTVALAALILAGIFLGWNSTAVHANFTDMFRLGSFDASLGVQAASFY
GLIVALCVAQSGSMFSADSWHDITIIAGEVRNPSRNLPLAMAFGCSAVIGLYILANAAYLVVLPLPAIQNAPSDRVATAM
LQAIFPGYGPTIMAIAIMISTFGCVNSLVLAGARAYYAMAKDGLFFKQAGVLNENRVPGWSLVVQGLWAVMLVLPRTYNV
ATRQYGNLYSNLLDYVISAALLFYILTIAGVFQLRRKRPDMARPYKVTGYPVVPAVFIIGAAIVLYMLFAYRPATTWPGL
VIVVIGAVVYAGVGRGAAARAA

Sequences:

>Translated_502_residues
MVYPAQSPSMTQPTLQKDTGFVRGLNLFDSTMVVIGVMIGSGIFIVSADMSRLINSPGWMLMAWVITGVLTLTAALSYGE
LASMLPHAGGMYVYLREAFSPLWGFLYGWTFFTVIQTGTIAAVAVAFARFSSIIFPAIGESRYLIPPVHITESYALSLST
AQLVAIAIIALLTWTNTRGLEYGKIVQNLFTSAKTVALAALILAGIFLGWNSTAVHANFTDMFRLGSFDASLGVQAASFY
GLIVALCVAQSGSMFSADSWHDITIIAGEVRNPSRNLPLAMAFGCSAVIGLYILANAAYLVVLPLPAIQNAPSDRVATAM
LQAIFPGYGPTIMAIAIMISTFGCVNSLVLAGARAYYAMAKDGLFFKQAGVLNENRVPGWSLVVQGLWAVMLVLPRTYNV
ATRQYGNLYSNLLDYVISAALLFYILTIAGVFQLRRKRPDMARPYKVTGYPVVPAVFIIGAAIVLYMLFAYRPATTWPGL
VIVVIGAVVYAGVGRGAAARAA
>Mature_502_residues
MVYPAQSPSMTQPTLQKDTGFVRGLNLFDSTMVVIGVMIGSGIFIVSADMSRLINSPGWMLMAWVITGVLTLTAALSYGE
LASMLPHAGGMYVYLREAFSPLWGFLYGWTFFTVIQTGTIAAVAVAFARFSSIIFPAIGESRYLIPPVHITESYALSLST
AQLVAIAIIALLTWTNTRGLEYGKIVQNLFTSAKTVALAALILAGIFLGWNSTAVHANFTDMFRLGSFDASLGVQAASFY
GLIVALCVAQSGSMFSADSWHDITIIAGEVRNPSRNLPLAMAFGCSAVIGLYILANAAYLVVLPLPAIQNAPSDRVATAM
LQAIFPGYGPTIMAIAIMISTFGCVNSLVLAGARAYYAMAKDGLFFKQAGVLNENRVPGWSLVVQGLWAVMLVLPRTYNV
ATRQYGNLYSNLLDYVISAALLFYILTIAGVFQLRRKRPDMARPYKVTGYPVVPAVFIIGAAIVLYMLFAYRPATTWPGL
VIVVIGAVVYAGVGRGAAARAA

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=451, Percent_Identity=28.6031042128603, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI7657591, Length=451, Percent_Identity=28.6031042128603, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI186910308, Length=454, Percent_Identity=28.8546255506608, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI186910306, Length=454, Percent_Identity=28.8546255506608, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI186910304, Length=454, Percent_Identity=28.8546255506608, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI115648063, Length=460, Percent_Identity=28.9130434782609, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI115648022, Length=460, Percent_Identity=28.9130434782609, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI33286428, Length=481, Percent_Identity=28.2744282744283, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI7657683, Length=439, Percent_Identity=26.6514806378132, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI71979932, Length=472, Percent_Identity=25.635593220339, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI9790235, Length=498, Percent_Identity=25.7028112449799, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507047, Length=471, Percent_Identity=23.9915074309979, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI258614005, Length=386, Percent_Identity=21.7616580310881, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI258614003, Length=386, Percent_Identity=21.7616580310881, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI114326544, Length=401, Percent_Identity=23.1920199501247, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI114326550, Length=401, Percent_Identity=23.1920199501247, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI33286430, Length=252, Percent_Identity=26.5873015873016, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI71999149, Length=434, Percent_Identity=23.7327188940092, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI258645169, Length=389, Percent_Identity=21.0796915167095, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87082250, Length=483, Percent_Identity=25.2587991718427, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI2367353, Length=425, Percent_Identity=24.4705882352941, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=483, Percent_Identity=28.5714285714286, Blast_Score=158, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17568033, Length=491, Percent_Identity=26.6802443991853, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32566699, Length=398, Percent_Identity=26.1306532663317, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71982608, Length=371, Percent_Identity=26.6846361185984, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982612, Length=371, Percent_Identity=26.6846361185984, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=430, Percent_Identity=24.4186046511628, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71982623, Length=302, Percent_Identity=27.4834437086093, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531343, Length=370, Percent_Identity=25.6756756756757, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71995388, Length=402, Percent_Identity=25.1243781094527, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71995382, Length=402, Percent_Identity=25.1243781094527, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=366, Percent_Identity=23.7704918032787, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193208714, Length=359, Percent_Identity=23.9554317548747, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32566695, Length=359, Percent_Identity=23.9554317548747, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=376, Percent_Identity=25, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221331183, Length=492, Percent_Identity=28.2520325203252, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17647653, Length=492, Percent_Identity=28.2520325203252, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24664379, Length=492, Percent_Identity=28.2520325203252, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21357367, Length=499, Percent_Identity=28.0561122244489, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI45550968, Length=485, Percent_Identity=28.0412371134021, Blast_Score=152, Evalue=7e-37,
Organism=Drosophila melanogaster, GI19921172, Length=485, Percent_Identity=28.0412371134021, Blast_Score=152, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24651635, Length=467, Percent_Identity=25.9100642398287, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24651633, Length=467, Percent_Identity=25.9100642398287, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24641995, Length=429, Percent_Identity=26.8065268065268, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24641993, Length=429, Percent_Identity=26.8065268065268, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24667468, Length=446, Percent_Identity=27.8026905829596, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24668806, Length=453, Percent_Identity=23.6203090507726, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356285, Length=453, Percent_Identity=23.6203090507726, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668802, Length=453, Percent_Identity=23.6203090507726, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53846; Mature: 53846

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYPAQSPSMTQPTLQKDTGFVRGLNLFDSTMVVIGVMIGSGIFIVSADMSRLINSPGWM
CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHH
LMAWVITGVLTLTAALSYGELASMLPHAGGMYVYLREAFSPLWGFLYGWTFFTVIQTGTI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHH
AAVAVAFARFSSIIFPAIGESRYLIPPVHITESYALSLSTAQLVAIAIIALLTWTNTRGL
HHHHHHHHHHHHHHHHCCCCCCEECCCCEECCHHHEEHHHHHHHHHHHHHHHHCCCCCCC
EYGKIVQNLFTSAKTVALAALILAGIFLGWNSTAVHANFTDMFRLGSFDASLGVQAASFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCHHHCCHHHHHH
GLIVALCVAQSGSMFSADSWHDITIIAGEVRNPSRNLPLAMAFGCSAVIGLYILANAAYL
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
VVLPLPAIQNAPSDRVATAMLQAIFPGYGPTIMAIAIMISTFGCVNSLVLAGARAYYAMA
EEECCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDGLFFKQAGVLNENRVPGWSLVVQGLWAVMLVLPRTYNVATRQYGNLYSNLLDYVISAA
HCCCEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLFYILTIAGVFQLRRKRPDMARPYKVTGYPVVPAVFIIGAAIVLYMLFAYRPATTWPGL
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VIVVIGAVVYAGVGRGAAARAA
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVYPAQSPSMTQPTLQKDTGFVRGLNLFDSTMVVIGVMIGSGIFIVSADMSRLINSPGWM
CCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHH
LMAWVITGVLTLTAALSYGELASMLPHAGGMYVYLREAFSPLWGFLYGWTFFTVIQTGTI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHH
AAVAVAFARFSSIIFPAIGESRYLIPPVHITESYALSLSTAQLVAIAIIALLTWTNTRGL
HHHHHHHHHHHHHHHHCCCCCCEECCCCEECCHHHEEHHHHHHHHHHHHHHHHCCCCCCC
EYGKIVQNLFTSAKTVALAALILAGIFLGWNSTAVHANFTDMFRLGSFDASLGVQAASFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCHHHCCHHHHHH
GLIVALCVAQSGSMFSADSWHDITIIAGEVRNPSRNLPLAMAFGCSAVIGLYILANAAYL
HHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
VVLPLPAIQNAPSDRVATAMLQAIFPGYGPTIMAIAIMISTFGCVNSLVLAGARAYYAMA
EEECCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDGLFFKQAGVLNENRVPGWSLVVQGLWAVMLVLPRTYNVATRQYGNLYSNLLDYVISAA
HCCCEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LLFYILTIAGVFQLRRKRPDMARPYKVTGYPVVPAVFIIGAAIVLYMLFAYRPATTWPGL
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VIVVIGAVVYAGVGRGAAARAA
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]