Click here to switch to the map view.

The map label for this gene is rsbU [H]

Identifier: 116620362

GI number: 116620362

Start: 1529884

End: 1530981

Strand: Direct

Name: rsbU [H]

Synonym: Acid_1239

Alternate gene names: 116620362

Gene position: 1529884-1530981 (Clockwise)

Preceding gene: 116620361

Following gene: 116620363

Centisome position: 15.35

GC content: 62.75

Gene sequence:

>1098_bases
ATGACGCGCAGGCTTCGAGATTTCTGGCAGCGGATCAGCGAAGGAATTGAGATCCAGCAGCTCTGGGCGCAGTTTCGCGC
CGACGCGCATTCGAGTTACCCGTTCTATTCCAAGGAAGTGAACCGTGAGCCTCTGGAAGGCGAATCCGGTTGGAAGCGCT
TCTGGCGGATCGCGCGCGGATTATTTTGGGCGATGGTGATGAAGCTCTCGCCCGCGCGGCGCGTATTGCTGCTGATCGCG
TTGGTGCTGTTGTTCCTTCCGCGCATCCAGGTCGGCGAACCGGGCCAGCGCAGCGACACCGTGGAGACGCAGGTCTCTGG
TGGTCTGATTTTGGTGGTACTGCTCGCGCTGGAACTCTCGGACCGCGTCGTGATGAAGCGGGATCTTGAGATCGCCCGCG
AGATTCAAAGCTGGCTAATGCCATCCGAAGCGCCGAAGGTGCCGGGCGTGGATATCGCCTTCGCCAGCCGTCCGGCGAAC
ACGGTCGCCGGGGATTACTACGACGCATTCTTTCGCCCCAACGAACGCCTGCTGATCGTTGTAGCGGACGTGGCCGGCAA
GAGCATTCCCGCCGCGCTGCTGACCGCCACGCTCCAGGCCAGTCTTCGCACACTGGCGGCACTGCCAGGGACGCTCCCTG
AGTTGGTGGGGAGCGTCAATCGCTACTCCTGCGAACAGAGCCTCCAGGGACGGCGGTTCACCACCGCCTTTCTGGCGGAG
TTGGAACCGGCCACCGGCGATCTGACCTATGTCAACGCCGGCCACAATTGGCCCGTGTTGAGGCGAGCTTCCGGCGCCAT
CGAGCGGCTCGAGGCCGGCGGCCTGCCGCTGGGCATTAGCGCCGCATTGCCCTATCAGTTTGGCTGCGCGAGGCTGACCG
CGGGCGACCTGCTATTGATTTTCACCGACGGCCTGGTGGAAGCCGAGGACGATGGGGAGCGCGAGTACGGAGAAGAACGA
ATGCTCCCGGTCGTGCAAACGCTTCACAGCGGGACGGCGAAAGAAGGGCTGACACGCGTCATGGAATCCGTGGACGCGTT
TGTGGGCCTCACGCGCCAGCATGATGACATTACGTGTCTGGTCTTGCGGATGACTTAG

Upstream 100 bases:

>100_bases
GACTTCGCGGCTCAGGTCGATTTGGGGACTGGGGATCGAGTTAGGCTTGGGGTGGTTTGCGACCAAGCCACCCGATTGGT
TCCGGTTATACTTGAGCCCA

Downstream 100 bases:

>100_bases
GGGCCGCCATACCTATGTAACATTCTGATGCTAGGGTGAAGGCAAAATGAATACTCGTGTTGCTCCCATCCGCATGGCAG
CCCTCCTGGTTTGTCTTGGG

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTRRLRDFWQRISEGIEIQQLWAQFRADAHSSYPFYSKEVNREPLEGESGWKRFWRIARGLFWAMVMKLSPARRVLLLIA
LVLLFLPRIQVGEPGQRSDTVETQVSGGLILVVLLALELSDRVVMKRDLEIAREIQSWLMPSEAPKVPGVDIAFASRPAN
TVAGDYYDAFFRPNERLLIVVADVAGKSIPAALLTATLQASLRTLAALPGTLPELVGSVNRYSCEQSLQGRRFTTAFLAE
LEPATGDLTYVNAGHNWPVLRRASGAIERLEAGGLPLGISAALPYQFGCARLTAGDLLLIFTDGLVEAEDDGEREYGEER
MLPVVQTLHSGTAKEGLTRVMESVDAFVGLTRQHDDITCLVLRMT

Sequences:

>Translated_365_residues
MTRRLRDFWQRISEGIEIQQLWAQFRADAHSSYPFYSKEVNREPLEGESGWKRFWRIARGLFWAMVMKLSPARRVLLLIA
LVLLFLPRIQVGEPGQRSDTVETQVSGGLILVVLLALELSDRVVMKRDLEIAREIQSWLMPSEAPKVPGVDIAFASRPAN
TVAGDYYDAFFRPNERLLIVVADVAGKSIPAALLTATLQASLRTLAALPGTLPELVGSVNRYSCEQSLQGRRFTTAFLAE
LEPATGDLTYVNAGHNWPVLRRASGAIERLEAGGLPLGISAALPYQFGCARLTAGDLLLIFTDGLVEAEDDGEREYGEER
MLPVVQTLHSGTAKEGLTRVMESVDAFVGLTRQHDDITCLVLRMT
>Mature_364_residues
TRRLRDFWQRISEGIEIQQLWAQFRADAHSSYPFYSKEVNREPLEGESGWKRFWRIARGLFWAMVMKLSPARRVLLLIAL
VLLFLPRIQVGEPGQRSDTVETQVSGGLILVVLLALELSDRVVMKRDLEIAREIQSWLMPSEAPKVPGVDIAFASRPANT
VAGDYYDAFFRPNERLLIVVADVAGKSIPAALLTATLQASLRTLAALPGTLPELVGSVNRYSCEQSLQGRRFTTAFLAEL
EPATGDLTYVNAGHNWPVLRRASGAIERLEAGGLPLGISAALPYQFGCARLTAGDLLLIFTDGLVEAEDDGEREYGEERM
LPVVQTLHSGTAKEGLTRVMESVDAFVGLTRQHDDITCLVLRMT

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 40482; Mature: 40351

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRLRDFWQRISEGIEIQQLWAQFRADAHSSYPFYSKEVNREPLEGESGWKRFWRIARG
CCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHH
LFWAMVMKLSPARRVLLLIALVLLFLPRIQVGEPGQRSDTVETQVSGGLILVVLLALELS
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHC
DRVVMKRDLEIAREIQSWLMPSEAPKVPGVDIAFASRPANTVAGDYYDAFFRPNERLLIV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCEEEEE
VADVAGKSIPAALLTATLQASLRTLAALPGTLPELVGSVNRYSCEQSLQGRRFTTAFLAE
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LEPATGDLTYVNAGHNWPVLRRASGAIERLEAGGLPLGISAALPYQFGCARLTAGDLLLI
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHCCCCCEEEE
FTDGLVEAEDDGEREYGEERMLPVVQTLHSGTAKEGLTRVMESVDAFVGLTRQHDDITCL
EECCCEECCCCCCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VLRMT
EEEEC
>Mature Secondary Structure 
TRRLRDFWQRISEGIEIQQLWAQFRADAHSSYPFYSKEVNREPLEGESGWKRFWRIARG
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHH
LFWAMVMKLSPARRVLLLIALVLLFLPRIQVGEPGQRSDTVETQVSGGLILVVLLALELS
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHC
DRVVMKRDLEIAREIQSWLMPSEAPKVPGVDIAFASRPANTVAGDYYDAFFRPNERLLIV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCEEEEE
VADVAGKSIPAALLTATLQASLRTLAALPGTLPELVGSVNRYSCEQSLQGRRFTTAFLAE
EECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LEPATGDLTYVNAGHNWPVLRRASGAIERLEAGGLPLGISAALPYQFGCARLTAGDLLLI
CCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHCCCCCEEEE
FTDGLVEAEDDGEREYGEERMLPVVQTLHSGTAKEGLTRVMESVDAFVGLTRQHDDITCL
EECCCEECCCCCCHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VLRMT
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]