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The map label for this gene is sipP [H]

Identifier: 116620294

GI number: 116620294

Start: 1440477

End: 1441457

Strand: Direct

Name: sipP [H]

Synonym: Acid_1171

Alternate gene names: 116620294

Gene position: 1440477-1441457 (Clockwise)

Preceding gene: 116620292

Following gene: 116620296

Centisome position: 14.45

GC content: 64.83

Gene sequence:

>981_bases
ATGACGGACCATTTCGAACCGGCGCCGCAGAGATCCATTGCGATCGCACTTGGCGTCGCGACAGCCCTGCTGCTCGGCGG
CGTTTGTCTGGCCGCGGGCCTGTGGAATCCGACCGCGGGATTGCCGCTGGCCGGGATCTTCCTAATCTCCGCGTACGGCA
TCTATCATCATCACAGTTGGAGCGCGTACGGCGCCGCACTGCTGCTGGCGGCGCTGGCGGCCGCCTCGTTCACCCTGCTC
GCGCGGGCGGGCGGCCCCGCCATTCCGGCGGCCGGCATCGTCCTCGACCTGGTGATTCTGGGAGCCGCTATCTTCGCACT
CTACCGCGCCGGAGCGCGCATGCCCGTCGGCTCCGCGCCGGGGCCGCGAAGTGCCTGGATCGCACTCGCCGTGCTGACCT
TCGTCTTCCCGCAATTCTGCCGCGCCTACATGATCGCCTCGTCCTCGATGGCCGACACGCTGCTGACCGGCGATCAGGTG
TTGGTACTCCCGCTTTCCAAGCCGCCGGCGCGCGGAGAGATCGTGCAACTCCGCTACGCCGCGGACCGTTCGCAGATGTT
TTTGAAGCGCGTGGTTGCGGTAGGCGGCGATCGCCTGCGAATCCGCAACAAGCAGCTCATCGTGAACGGAACGCCGGTCA
ACGAGCCTTACGCCACCCATCGCACCGGCTTCACCTACGATTTCCGGGACAACTTCCCGGCGCCAGCAACCATCAATCTG
CCGCTCCCATGGGCTGAGCAATTGCGAGCCAGAACCGTGAACGGAGAGCTGGTTATTCCGGCCGGCAAGTTCTTCGTGCT
GGGCGATAACCGCGACGAATCCCTGGACAGCCGCTACTTCGGATTCCTGGATCAGAGCGACCTTGCGGGGCACCCCGTGC
TGGTCTACTTTTCGTCTGTCAAGACCGATCCGCCCACGAACTCGCCCGTATTGCTGCACCCTTCGCGCATCCGCTGGGAT
CGCATCTTCAAGGCACTCTAG

Upstream 100 bases:

>100_bases
CAACAGCCCCAATGCCCTTCGAGAAATCACGGGACCACCTTGCCCGAAGGATAACAGATTCCCGGGGAACTATACCGGTG
TCCACGGCGTAGTATCTGGC

Downstream 100 bases:

>100_bases
TCGCGTAACGCAGCGATACGAACCCGGCCGCGCTGCCGGTCCGGGTAAGGGCATAGAGCCAATCGAAGTCCGAGTCTTCG
ATGACGATCCCCGCCGGTCC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTDHFEPAPQRSIAIALGVATALLLGGVCLAAGLWNPTAGLPLAGIFLISAYGIYHHHSWSAYGAALLLAALAAASFTLL
ARAGGPAIPAAGIVLDLVILGAAIFALYRAGARMPVGSAPGPRSAWIALAVLTFVFPQFCRAYMIASSSMADTLLTGDQV
LVLPLSKPPARGEIVQLRYAADRSQMFLKRVVAVGGDRLRIRNKQLIVNGTPVNEPYATHRTGFTYDFRDNFPAPATINL
PLPWAEQLRARTVNGELVIPAGKFFVLGDNRDESLDSRYFGFLDQSDLAGHPVLVYFSSVKTDPPTNSPVLLHPSRIRWD
RIFKAL

Sequences:

>Translated_326_residues
MTDHFEPAPQRSIAIALGVATALLLGGVCLAAGLWNPTAGLPLAGIFLISAYGIYHHHSWSAYGAALLLAALAAASFTLL
ARAGGPAIPAAGIVLDLVILGAAIFALYRAGARMPVGSAPGPRSAWIALAVLTFVFPQFCRAYMIASSSMADTLLTGDQV
LVLPLSKPPARGEIVQLRYAADRSQMFLKRVVAVGGDRLRIRNKQLIVNGTPVNEPYATHRTGFTYDFRDNFPAPATINL
PLPWAEQLRARTVNGELVIPAGKFFVLGDNRDESLDSRYFGFLDQSDLAGHPVLVYFSSVKTDPPTNSPVLLHPSRIRWD
RIFKAL
>Mature_325_residues
TDHFEPAPQRSIAIALGVATALLLGGVCLAAGLWNPTAGLPLAGIFLISAYGIYHHHSWSAYGAALLLAALAAASFTLLA
RAGGPAIPAAGIVLDLVILGAAIFALYRAGARMPVGSAPGPRSAWIALAVLTFVFPQFCRAYMIASSSMADTLLTGDQVL
VLPLSKPPARGEIVQLRYAADRSQMFLKRVVAVGGDRLRIRNKQLIVNGTPVNEPYATHRTGFTYDFRDNFPAPATINLP
LPWAEQLRARTVNGELVIPAGKFFVLGDNRDESLDSRYFGFLDQSDLAGHPVLVYFSSVKTDPPTNSPVLLHPSRIRWDR
IFKAL

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 35057; Mature: 34926

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHFEPAPQRSIAIALGVATALLLGGVCLAAGLWNPTAGLPLAGIFLISAYGIYHHHSW
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCH
SAYGAALLLAALAAASFTLLARAGGPAIPAAGIVLDLVILGAAIFALYRAGARMPVGSAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPRSAWIALAVLTFVFPQFCRAYMIASSSMADTLLTGDQVLVLPLSKPPARGEIVQLRYA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEC
ADRSQMFLKRVVAVGGDRLRIRNKQLIVNGTPVNEPYATHRTGFTYDFRDNFPAPATINL
CCHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEC
PLPWAEQLRARTVNGELVIPAGKFFVLGDNRDESLDSRYFGFLDQSDLAGHPVLVYFSSV
CCCHHHHHHHEECCCCEEEECCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEECC
KTDPPTNSPVLLHPSRIRWDRIFKAL
CCCCCCCCCEEECCCHHHHHHHHHCC
>Mature Secondary Structure 
TDHFEPAPQRSIAIALGVATALLLGGVCLAAGLWNPTAGLPLAGIFLISAYGIYHHHSW
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCH
SAYGAALLLAALAAASFTLLARAGGPAIPAAGIVLDLVILGAAIFALYRAGARMPVGSAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPRSAWIALAVLTFVFPQFCRAYMIASSSMADTLLTGDQVLVLPLSKPPARGEIVQLRYA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEC
ADRSQMFLKRVVAVGGDRLRIRNKQLIVNGTPVNEPYATHRTGFTYDFRDNFPAPATINL
CCHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCEEEEC
PLPWAEQLRARTVNGELVIPAGKFFVLGDNRDESLDSRYFGFLDQSDLAGHPVLVYFSSV
CCCHHHHHHHEECCCCEEEECCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEECC
KTDPPTNSPVLLHPSRIRWDRIFKAL
CCCCCCCCCEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]