Click here to switch to the map view.

The map label for this gene is hfq [H]

Identifier: 116620285

GI number: 116620285

Start: 1433514

End: 1433819

Strand: Reverse

Name: hfq [H]

Synonym: Acid_1162

Alternate gene names: 116620285

Gene position: 1433819-1433514 (Counterclockwise)

Preceding gene: 116620286

Following gene: 116620284

Centisome position: 14.39

GC content: 51.63

Gene sequence:

>306_bases
ATGGATAAACCGGCGCAAAATATTCAAGATAGCTTTCTAAACAATGCCAGGAAGGACAAAATTGTCCTTACCATCTATTT
GATGAGCGGCGTCAAACTTTCGGGCCGAATCAAAAGTTTTGACAAGTATTCGTTGGTCCTCGAAACCAACAATCAGGAAC
AGTTGATCTTCAAGCACGCCATTTCCACGGTGGTTACGCAGAAAACGGCGCACTCTTATTCGAGCAACTCGCCTGTCGCG
AGCCACACCGCGGCGGCTGCAACCGCACCCGGCGCGCCGGCGCATGCGGATTCACCGGAGGCATAG

Upstream 100 bases:

>100_bases
CCAGGGATACCCCCACCGCGGGCAGTGAATAGTTGTACAATACTATGGCATTGTAACAACTGCTTTACTCGCCCGAGTCA
TGGGCTTTTTGGGGGATGGC

Downstream 100 bases:

>100_bases
CAACGGCACTCCGTAACGCCGCTCCCGAACGCGCCATCCTGGTCGGCCTGGATTGGAAAACGCGTGGAGGAGGCGGGCGA
ACCAACGCTCTTCGAGCCGA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MDKPAQNIQDSFLNNARKDKIVLTIYLMSGVKLSGRIKSFDKYSLVLETNNQEQLIFKHAISTVVTQKTAHSYSSNSPVA
SHTAAAATAPGAPAHADSPEA

Sequences:

>Translated_101_residues
MDKPAQNIQDSFLNNARKDKIVLTIYLMSGVKLSGRIKSFDKYSLVLETNNQEQLIFKHAISTVVTQKTAHSYSSNSPVA
SHTAAAATAPGAPAHADSPEA
>Mature_101_residues
MDKPAQNIQDSFLNNARKDKIVLTIYLMSGVKLSGRIKSFDKYSLVLETNNQEQLIFKHAISTVVTQKTAHSYSSNSPVA
SHTAAAATAPGAPAHADSPEA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=98, Percent_Identity=37.7551020408163, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 10856; Mature: 10856

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKPAQNIQDSFLNNARKDKIVLTIYLMSGVKLSGRIKSFDKYSLVLETNNQEQLIFKHA
CCCCHHHHHHHHHCCCCCCEEEEEEEEECCEEECCCCCCCCEEEEEEECCCCHHHHHHHH
ISTVVTQKTAHSYSSNSPVASHTAAAATAPGAPAHADSPEA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDKPAQNIQDSFLNNARKDKIVLTIYLMSGVKLSGRIKSFDKYSLVLETNNQEQLIFKHA
CCCCHHHHHHHHHCCCCCCEEEEEEEEECCEEECCCCCCCCEEEEEEECCCCHHHHHHHH
ISTVVTQKTAHSYSSNSPVASHTAAAATAPGAPAHADSPEA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA