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The map label for this gene is icfA [H]

Identifier: 116620283

GI number: 116620283

Start: 1431286

End: 1431894

Strand: Direct

Name: icfA [H]

Synonym: Acid_1160

Alternate gene names: 116620283

Gene position: 1431286-1431894 (Clockwise)

Preceding gene: 116620282

Following gene: 116620292

Centisome position: 14.36

GC content: 63.38

Gene sequence:

>609_bases
ATGAAAGACCTTCTGGAAGGATATCGACGCTTTCGCGCTAAGGGCTGGCCCGAGCAACGAGGGGTCTTCGAAACTCTGGC
GAGGGACGGCCAAGCGCCGAAAGCCATGGTGGTGGCGTGCGTGGATAGCAGGGTGGACCCCGCGATGATCTTCGACGCAG
GTCCGGGCGAGATCCTCACGGTCCGCAATGTGGCCAACCTGGTGCCGCCCTATGCACCGGACGCAGCCTATCACGGCACC
AGCGCGGCCCTGGAATTCGGAGTGCGCGTGCTCCAAGTCCGGCACGTGATGGTGATGGGCCACGGCCTATGCGGCGGGGT
GCGGGCGCTGCTCGAAGGCGCTCCCGGCCCGGGGCACGAATTCGTCGCTCCCTGGATGTCGATTGCGGAGACCGCGCGGG
TCCACGTAATGAAATCGGTGCCCGCCGAGCAGCGCCAGCAGGCGTGTGAATGGGAAGCGATTAAGGTGTCACTGGCAAAC
CTTCTGACATTTCCCTGGATTGCCGAACGGGTCGGGACGGGCAAACTCGCCCTCCACGGTACGTGGTTCGATATCCACAC
CGGCGAACTGATGATTCTACAGGCGGACGACCGGTTCGTTCCTGCATAA

Upstream 100 bases:

>100_bases
ACCGTCGCTCTAGCCAGCTGAGCTACGCCGCCAAGATCGGAGTTTTTATTTTACCAAAGTGGTCCCGTGGAATGCCAATT
TCAGCTTAAATTGAAGGTTC

Downstream 100 bases:

>100_bases
GTCCGGCCACCAATCGGGTGATCCCCTGTATAGATTTGTGGAAATCCTTTCCTTCACCGCTCTGGATTTCTTAGCCGATT
TGTAACCCGTCTGCTGAGGT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKDLLEGYRRFRAKGWPEQRGVFETLARDGQAPKAMVVACVDSRVDPAMIFDAGPGEILTVRNVANLVPPYAPDAAYHGT
SAALEFGVRVLQVRHVMVMGHGLCGGVRALLEGAPGPGHEFVAPWMSIAETARVHVMKSVPAEQRQQACEWEAIKVSLAN
LLTFPWIAERVGTGKLALHGTWFDIHTGELMILQADDRFVPA

Sequences:

>Translated_202_residues
MKDLLEGYRRFRAKGWPEQRGVFETLARDGQAPKAMVVACVDSRVDPAMIFDAGPGEILTVRNVANLVPPYAPDAAYHGT
SAALEFGVRVLQVRHVMVMGHGLCGGVRALLEGAPGPGHEFVAPWMSIAETARVHVMKSVPAEQRQQACEWEAIKVSLAN
LLTFPWIAERVGTGKLALHGTWFDIHTGELMILQADDRFVPA
>Mature_202_residues
MKDLLEGYRRFRAKGWPEQRGVFETLARDGQAPKAMVVACVDSRVDPAMIFDAGPGEILTVRNVANLVPPYAPDAAYHGT
SAALEFGVRVLQVRHVMVMGHGLCGGVRALLEGAPGPGHEFVAPWMSIAETARVHVMKSVPAEQRQQACEWEAIKVSLAN
LLTFPWIAERVGTGKLALHGTWFDIHTGELMILQADDRFVPA

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=205, Percent_Identity=31.219512195122, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786318, Length=179, Percent_Identity=31.8435754189944, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24645213, Length=239, Percent_Identity=25.1046025104602, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22081; Mature: 22081

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLEGYRRFRAKGWPEQRGVFETLARDGQAPKAMVVACVDSRVDPAMIFDAGPGEILT
CHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCHHEEEEECCCCCCCEEEEECCCCCEEE
VRNVANLVPPYAPDAAYHGTSAALEFGVRVLQVRHVMVMGHGLCGGVRALLEGAPGPGHE
ECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
FVAPWMSIAETARVHVMKSVPAEQRQQACEWEAIKVSLANLLTFPWIAERVGTGKLALHG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
TWFDIHTGELMILQADDRFVPA
EEEEEECCEEEEEECCCCCCCC
>Mature Secondary Structure
MKDLLEGYRRFRAKGWPEQRGVFETLARDGQAPKAMVVACVDSRVDPAMIFDAGPGEILT
CHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCCCHHEEEEECCCCCCCEEEEECCCCCEEE
VRNVANLVPPYAPDAAYHGTSAALEFGVRVLQVRHVMVMGHGLCGGVRALLEGAPGPGHE
ECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
FVAPWMSIAETARVHVMKSVPAEQRQQACEWEAIKVSLANLLTFPWIAERVGTGKLALHG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
TWFDIHTGELMILQADDRFVPA
EEEEEECCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]