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The map label for this gene is atoS [C]

Identifier: 116620233

GI number: 116620233

Start: 1365753

End: 1367897

Strand: Reverse

Name: atoS [C]

Synonym: Acid_1110

Alternate gene names: 116620233

Gene position: 1367897-1365753 (Counterclockwise)

Preceding gene: 116620243

Following gene: 116620230

Centisome position: 13.73

GC content: 59.91

Gene sequence:

>2145_bases
ATGTTGGATCGGAGATGGTTACCCTGGCTATACCCCAAGTCAACCGGCGACCCGGGGTCCGACCGCAACTCCCGCACTCT
GCAATTCTCCTGCTACCTCTTGGCTTCGGCTGCCGTCGCGGTCTTGATGGTGAGCGCCATCGATCGCGAGTGGCAACAAA
TGCCTCTACTGGTCTCAGCGATCGCGGGCCTGGTTGCCGCCGTGGCCTTGAGTCGTGCGGGGAGGTCGGATTGGGCGGGG
CGGACCGCATTCCTGATCGTGCTGCTGAGCGCAATTCTGCTGGTTTTCCGGGCGCATGACGGATTTCGCAGTCACTCCAT
GCTCCTTTTCCCCGGGTTGCTGCTCATCTCCCTGATGATGCTGGATCGTGCGTCCTACGTGGCAACCGCGGCTATCGTGG
TAGTGACGGTGGCAGCGCTGGGTGTCGCCGTAAAACATGGCCTCACGCGGGCTACCCCGCCGGTCCGTACGACCTACGAT
TCCATATTCTATGTAGACCTGAATATGCTGGTCATCGCGATCATCGGCAGCCGGATCGCCCGCGATACTCAGAGGAACAC
CTTCGACCTGGGCGTCAGCATCGACCGGTTGTCTGCCGCAAACCTCGAATTGATTCAAGTCAGGGAGCATCTGCAGGACA
GCGAAGAGCGTCTAAAGAGCGCCCAACGTTTGACTCATGTGGGCAGCTGGCATTGGAATCTGGGAACGAATCAAGTGGTG
TGCTCCGAAGAATGCAAACAGATTTTCGGCCAGCCAGAGGATTACGCGCCCAGCTTAGAAGAACTACTCCAAATCATCAG
GCCCAACGACAGAGCGCGCGTGGCCAGCGAGATTCAACGCGGTATTGCAGAGAAGAGCGGGTGTTCCACGGAGTTTCAGA
TCGTCCAGCCGAACGGCGAGGTGCGTACGGTTACGTTCACCAGCCAGGTGTTGCTCGATGACGCCGGCTCGCCGCGACAC
ATCTTTGGCGCCTGCCAGGACGTCACCGATGAGCGGCGTATGCAAGAGGAGTCCCTCGCCAGCCAGAAGCTGGAGACCGT
GGGCACGCTGGCCAATGGAATTGCCCACGACTTCAACAACCTCCTGGGCGGCGTGCTGGCGCAAGCCGAAATGGGCTTAT
CGGAACTGGCGGCCGGATCGCGTCCGGAAGCGGCGCTGAAAGCTATCTGCTGTGCCGCGGTGAGCGGCTCGGAGATCGTC
CGCCAGTTAATGATCTACACAGGACAGGAGCGTGAGCCGCGCGACCTGGTAGACGTTGCACGGACGGTAGAGGAAATGGC
TGACTTCCTCAAGCTTTCGATCTCGAAACTGGCAACTCTGCACACTGATTTTGACAAGGATCTTCCGCCGGTTCGGGCCA
GTGGCGCACAGATCCGGCAAATCGTAATGAACCTTGTAATGAATGCATCCGAGGCGATTGGAGATCGAGAAGGAGTGATC
CGCCTGACGGTACGGCGCTTCCAGGCAGGACAGGACCAGGCTGGGTGTATCGCGGGAGCGTTGGCGGAGCGGGATTGCGT
GGGCCTGGAAGTCGCTGACACCGGGCGAGGGATGTCGCCGGAAACGCAGGCTCGCGTATTCGACCCATTCTTTACGACCA
AGCCCTTACGACACGGGCTTGGGCTTGCCGTTGTCTCCGGAATCGTCAGGATGCTGGCAGGCGGGATCCATCTCGCCAGC
GAGCCGGGGAAGGGCACTATTTTTCGAGTATTGCTGCCTTGTGAGGAGGGGGCGGCGAACGATTCTCCGCGCCCGAACAC
CGCCACCGAGTCAACGAACGCAAGTCAGGCTGCGACCGCCCTGGTTGTGGAGGACGAAGATTCACTGCGGGGCCCGGCCG
CGAAGATGCTTCGCAAGAGTGGTTTCACTGTCCTTGAGGCCCCGGATGGGACTACAGCCCTCGGGATAATTCGAGGAGAC
AGAGCCATAGAGGTGCTTCTCCTGGATGTCACTCTCCCCGGAACTCCGAGCCAAGAGGTGCTTGCAGAGGCCAAGCGCCT
AAGACCCGCTATGCGGGTGATCGTCACCAGCGCGTACGGCAAGGAATTCGCCGCCACCTCATTACAAGCGGATGTCGAGC
GATTCATCCGAAAGCCGTACTCGCTCCGCGATCTTGTAGAGTTGGTTCGTCAAACGCTCTCGTGA

Upstream 100 bases:

>100_bases
TGGCCGCAAGACAACGGGCGAATTGGAGTAAAATGCCTGGAGCCCCAACACGCGCCGACATTCAGTTTCAATGAAGGACA
AAAAGAGGCCTCAGACCTTC

Downstream 100 bases:

>100_bases
GGACGCCAGACAGTCATGCAGCGAGAAATGTGGGAAGGCACGAGTTGCCCCGGTCTTACTTCGAGTGCAGCAGACCCTGC
TTCCAATCGAGACCCAGAGA

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MLDRRWLPWLYPKSTGDPGSDRNSRTLQFSCYLLASAAVAVLMVSAIDREWQQMPLLVSAIAGLVAAVALSRAGRSDWAG
RTAFLIVLLSAILLVFRAHDGFRSHSMLLFPGLLLISLMMLDRASYVATAAIVVVTVAALGVAVKHGLTRATPPVRTTYD
SIFYVDLNMLVIAIIGSRIARDTQRNTFDLGVSIDRLSAANLELIQVREHLQDSEERLKSAQRLTHVGSWHWNLGTNQVV
CSEECKQIFGQPEDYAPSLEELLQIIRPNDRARVASEIQRGIAEKSGCSTEFQIVQPNGEVRTVTFTSQVLLDDAGSPRH
IFGACQDVTDERRMQEESLASQKLETVGTLANGIAHDFNNLLGGVLAQAEMGLSELAAGSRPEAALKAICCAAVSGSEIV
RQLMIYTGQEREPRDLVDVARTVEEMADFLKLSISKLATLHTDFDKDLPPVRASGAQIRQIVMNLVMNASEAIGDREGVI
RLTVRRFQAGQDQAGCIAGALAERDCVGLEVADTGRGMSPETQARVFDPFFTTKPLRHGLGLAVVSGIVRMLAGGIHLAS
EPGKGTIFRVLLPCEEGAANDSPRPNTATESTNASQAATALVVEDEDSLRGPAAKMLRKSGFTVLEAPDGTTALGIIRGD
RAIEVLLLDVTLPGTPSQEVLAEAKRLRPAMRVIVTSAYGKEFAATSLQADVERFIRKPYSLRDLVELVRQTLS

Sequences:

>Translated_714_residues
MLDRRWLPWLYPKSTGDPGSDRNSRTLQFSCYLLASAAVAVLMVSAIDREWQQMPLLVSAIAGLVAAVALSRAGRSDWAG
RTAFLIVLLSAILLVFRAHDGFRSHSMLLFPGLLLISLMMLDRASYVATAAIVVVTVAALGVAVKHGLTRATPPVRTTYD
SIFYVDLNMLVIAIIGSRIARDTQRNTFDLGVSIDRLSAANLELIQVREHLQDSEERLKSAQRLTHVGSWHWNLGTNQVV
CSEECKQIFGQPEDYAPSLEELLQIIRPNDRARVASEIQRGIAEKSGCSTEFQIVQPNGEVRTVTFTSQVLLDDAGSPRH
IFGACQDVTDERRMQEESLASQKLETVGTLANGIAHDFNNLLGGVLAQAEMGLSELAAGSRPEAALKAICCAAVSGSEIV
RQLMIYTGQEREPRDLVDVARTVEEMADFLKLSISKLATLHTDFDKDLPPVRASGAQIRQIVMNLVMNASEAIGDREGVI
RLTVRRFQAGQDQAGCIAGALAERDCVGLEVADTGRGMSPETQARVFDPFFTTKPLRHGLGLAVVSGIVRMLAGGIHLAS
EPGKGTIFRVLLPCEEGAANDSPRPNTATESTNASQAATALVVEDEDSLRGPAAKMLRKSGFTVLEAPDGTTALGIIRGD
RAIEVLLLDVTLPGTPSQEVLAEAKRLRPAMRVIVTSAYGKEFAATSLQADVERFIRKPYSLRDLVELVRQTLS
>Mature_714_residues
MLDRRWLPWLYPKSTGDPGSDRNSRTLQFSCYLLASAAVAVLMVSAIDREWQQMPLLVSAIAGLVAAVALSRAGRSDWAG
RTAFLIVLLSAILLVFRAHDGFRSHSMLLFPGLLLISLMMLDRASYVATAAIVVVTVAALGVAVKHGLTRATPPVRTTYD
SIFYVDLNMLVIAIIGSRIARDTQRNTFDLGVSIDRLSAANLELIQVREHLQDSEERLKSAQRLTHVGSWHWNLGTNQVV
CSEECKQIFGQPEDYAPSLEELLQIIRPNDRARVASEIQRGIAEKSGCSTEFQIVQPNGEVRTVTFTSQVLLDDAGSPRH
IFGACQDVTDERRMQEESLASQKLETVGTLANGIAHDFNNLLGGVLAQAEMGLSELAAGSRPEAALKAICCAAVSGSEIV
RQLMIYTGQEREPRDLVDVARTVEEMADFLKLSISKLATLHTDFDKDLPPVRASGAQIRQIVMNLVMNASEAIGDREGVI
RLTVRRFQAGQDQAGCIAGALAERDCVGLEVADTGRGMSPETQARVFDPFFTTKPLRHGLGLAVVSGIVRMLAGGIHLAS
EPGKGTIFRVLLPCEEGAANDSPRPNTATESTNASQAATALVVEDEDSLRGPAAKMLRKSGFTVLEAPDGTTALGIIRGD
RAIEVLLLDVTLPGTPSQEVLAEAKRLRPAMRVIVTSAYGKEFAATSLQADVERFIRKPYSLRDLVELVRQTLS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=25.6, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=28.3950617283951, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=23.4957020057307, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=432, Percent_Identity=23.1481481481481, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=25.6505576208178, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=307, Percent_Identity=25.0814332247557, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=342, Percent_Identity=23.9766081871345, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77445; Mature: 77445

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRRWLPWLYPKSTGDPGSDRNSRTLQFSCYLLASAAVAVLMVSAIDREWQQMPLLVSA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLVAAVALSRAGRSDWAGRTAFLIVLLSAILLVFRAHDGFRSHSMLLFPGLLLISLMM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LDRASYVATAAIVVVTVAALGVAVKHGLTRATPPVRTTYDSIFYVDLNMLVIAIIGSRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
RDTQRNTFDLGVSIDRLSAANLELIQVREHLQDSEERLKSAQRLTHVGSWHWNLGTNQVV
HHHCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEE
CSEECKQIFGQPEDYAPSLEELLQIIRPNDRARVASEIQRGIAEKSGCSTEFQIVQPNGE
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VRTVTFTSQVLLDDAGSPRHIFGACQDVTDERRMQEESLASQKLETVGTLANGIAHDFNN
EEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGGVLAQAEMGLSELAAGSRPEAALKAICCAAVSGSEIVRQLMIYTGQEREPRDLVDVA
HHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
RTVEEMADFLKLSISKLATLHTDFDKDLPPVRASGAQIRQIVMNLVMNASEAIGDREGVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
RLTVRRFQAGQDQAGCIAGALAERDCVGLEVADTGRGMSPETQARVFDPFFTTKPLRHGL
EEEHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHEECCHHHCCHHHHCC
GLAVVSGIVRMLAGGIHLASEPGKGTIFRVLLPCEEGAANDSPRPNTATESTNASQAATA
HHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHEEE
LVVEDEDSLRGPAAKMLRKSGFTVLEAPDGTTALGIIRGDRAIEVLLLDVTLPGTPSQEV
EEEECCHHCCCHHHHHHHHCCCEEEECCCCCEEEEEEECCCEEEEEEEEEECCCCCCHHH
LAEAKRLRPAMRVIVTSAYGKEFAATSLQADVERFIRKPYSLRDLVELVRQTLS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLDRRWLPWLYPKSTGDPGSDRNSRTLQFSCYLLASAAVAVLMVSAIDREWQQMPLLVSA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGLVAAVALSRAGRSDWAGRTAFLIVLLSAILLVFRAHDGFRSHSMLLFPGLLLISLMM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LDRASYVATAAIVVVTVAALGVAVKHGLTRATPPVRTTYDSIFYVDLNMLVIAIIGSRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHH
RDTQRNTFDLGVSIDRLSAANLELIQVREHLQDSEERLKSAQRLTHVGSWHWNLGTNQVV
HHHCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEE
CSEECKQIFGQPEDYAPSLEELLQIIRPNDRARVASEIQRGIAEKSGCSTEFQIVQPNGE
HHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VRTVTFTSQVLLDDAGSPRHIFGACQDVTDERRMQEESLASQKLETVGTLANGIAHDFNN
EEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGGVLAQAEMGLSELAAGSRPEAALKAICCAAVSGSEIVRQLMIYTGQEREPRDLVDVA
HHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
RTVEEMADFLKLSISKLATLHTDFDKDLPPVRASGAQIRQIVMNLVMNASEAIGDREGVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
RLTVRRFQAGQDQAGCIAGALAERDCVGLEVADTGRGMSPETQARVFDPFFTTKPLRHGL
EEEHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHEECCHHHCCHHHHCC
GLAVVSGIVRMLAGGIHLASEPGKGTIFRVLLPCEEGAANDSPRPNTATESTNASQAATA
HHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHEEE
LVVEDEDSLRGPAAKMLRKSGFTVLEAPDGTTALGIIRGDRAIEVLLLDVTLPGTPSQEV
EEEECCHHCCCHHHHHHHHCCCEEEECCCCCEEEEEEECCCEEEEEEEEEECCCCCCHHH
LAEAKRLRPAMRVIVTSAYGKEFAATSLQADVERFIRKPYSLRDLVELVRQTLS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA