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The map label for this gene is sglT [H]

Identifier: 116620230

GI number: 116620230

Start: 1359812

End: 1361521

Strand: Reverse

Name: sglT [H]

Synonym: Acid_1107

Alternate gene names: 116620230

Gene position: 1361521-1359812 (Counterclockwise)

Preceding gene: 116620233

Following gene: 116620227

Centisome position: 13.66

GC content: 60.99

Gene sequence:

>1710_bases
ATGACAACGCTTGATTGGTTTGTCCTGGTGCTGGCGCTGGTTTCGATAATTGCGTACGGGCTGTATCGCAGCCGCGGGAG
CGATACGGTAGACCGGTACCTGCTGGCGGGAAAGAGCATGCCGTGGTATGCGATGGCGCTCTCGATCATGGCGACGCAGG
CGAGCGCGATCACGTTCATTTCGACGACCGGGCAAAGCTACATCGACGGAATGCGGTTCGTGCAGTTTTATTTCGGGCTG
CCGCTGGCGATGGTGGTGATCTGCGCGACCGTGGTTCCGATGTTCCACCATGCGCGCGTTTACACGGCGTACGAATACCT
GGAGAAGCGGTTCGACACCAAGACGAGGGCGCTGGGAAGCATCATCTTTCTGTGCCAGCGCGGGCTTTCCGCGGGGCTGA
CGATTTACGCTCCGGCGCTGGTGCTCTCGGTGATTCTGGGCTGGCCGGAACGCATGACAACGATCCTGATGGGCGCGACG
GTAGTGACGTACACGGTGCTCGGCGGGATCAAGGCGGTAACGTGGAGCGACGTGCAGCAGATGGGGGTGATCTTCGCCGG
ACTGGTGATCTCGCTGGTTACAGTGATCGTGCTGCTGCCGCACTCGGTATCGTTCGGCGACGCGGTATTTCTAGCAGGGG
CGGCGGGGCGGCTGAATGCGGTGACAACGAACTTCGATTGGAACGACCGCTTTAATTTGTGGAGCGGCCTGATCGGCGGC
ACGTTCCTCTTTCTCTCCTATTTCGGGTGCGACCAATCGCAGGTGCAGCGCTACCTGACCGGCAGATCGATTGCGCAGAG
CCGGTTGAGCCTGCTGTTCAACGCGGTGGCGAAGATCCCGATGCAGTTCTTCATCCTGTTCATCGGGGCGATGGTGTTCG
TGTTTTACCTCTTCGTGCAGCCGCCATTGTTATTTCAGCAGGCGGAGCTGAAGCGGATCGGGAGGCAGAGCGAGTTCGCG
CCCATGAGCGAGCAGTACGATCGCGCGTTCGAGCAGCGCAAGCGAGCGGCGCTGGCGCTGGTGGAGGCGCATCACGCGGG
CGACGCGGCGGGCGAGGCGCGGCAGCGGGCCGAATATCGCGCGGCGCAGGGTGAATTGGACGCCGCGCGGAGGAGCGCCT
CGAAGCTGGTGGAGCAGACCGGTGGCGAGAAGGGCTTCAACGACACGAATTACATTTTTCTTTCATTCGTGACCAAGTAC
CTGCCCTCCGGCGTGGTGGGGCTGGTGATCGCGGTGATCTTCGCGGCGACGATGTCCGCAAGCTCGGGAGAGATCAACTC
GCTGGCGACTGTGAGCGTGATCGACATTTATCAACGGCATTTCAGGCGCGGCCAGAGCGATCACCATTATTTGATGGCGT
CCCGATGGTTGACGCTGTTCTGGGGTGTATACGCGGTGGTGTTCGCGGGGTGGGCGAGGCGGCTGGGATCGTTAATCGTG
GCGGTGAACAAAGTGGGATCGCTGTTCTACGGGTCGCTGCTGGGATGTTTCGCGCTGGCGATTCTGTTCCCGAGGGTGCG
CGGCACGGCGGTATTCACGGGAATGATCCTGGGCGAGGCTGCGATCTTCGCGACGGCGTGGTTCACGGATGTCTCGTGGC
TCTGGTACAACGTGATCGGGTGCGCGGTGGTGATGGTAACGGCGCTGATCATTACGTACGCTTCGCCCGGAACCACTTTC
GCCAGACCAGATACGCAAGCACAAGAATAA

Upstream 100 bases:

>100_bases
CGCCGCCGTTTCTCGGCACGTGGCGCCGGGTGTACATCGCCGTCCTGATCTATCTGGTCCTGATCATTTTCAGCGCATAT
CTGTTTACCCGGTTTTATCG

Downstream 100 bases:

>100_bases
CGGAGGCGATCACGCCGCCGAGCAGGTAGGCCTCCAGGTGGCCCTGCACGTCTTTCCAGCGTTCGCCAAGGAAGTAGCCG
AGGCCGATGAAGGTGCCGGC

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MTTLDWFVLVLALVSIIAYGLYRSRGSDTVDRYLLAGKSMPWYAMALSIMATQASAITFISTTGQSYIDGMRFVQFYFGL
PLAMVVICATVVPMFHHARVYTAYEYLEKRFDTKTRALGSIIFLCQRGLSAGLTIYAPALVLSVILGWPERMTTILMGAT
VVTYTVLGGIKAVTWSDVQQMGVIFAGLVISLVTVIVLLPHSVSFGDAVFLAGAAGRLNAVTTNFDWNDRFNLWSGLIGG
TFLFLSYFGCDQSQVQRYLTGRSIAQSRLSLLFNAVAKIPMQFFILFIGAMVFVFYLFVQPPLLFQQAELKRIGRQSEFA
PMSEQYDRAFEQRKRAALALVEAHHAGDAAGEARQRAEYRAAQGELDAARRSASKLVEQTGGEKGFNDTNYIFLSFVTKY
LPSGVVGLVIAVIFAATMSASSGEINSLATVSVIDIYQRHFRRGQSDHHYLMASRWLTLFWGVYAVVFAGWARRLGSLIV
AVNKVGSLFYGSLLGCFALAILFPRVRGTAVFTGMILGEAAIFATAWFTDVSWLWYNVIGCAVVMVTALIITYASPGTTF
ARPDTQAQE

Sequences:

>Translated_569_residues
MTTLDWFVLVLALVSIIAYGLYRSRGSDTVDRYLLAGKSMPWYAMALSIMATQASAITFISTTGQSYIDGMRFVQFYFGL
PLAMVVICATVVPMFHHARVYTAYEYLEKRFDTKTRALGSIIFLCQRGLSAGLTIYAPALVLSVILGWPERMTTILMGAT
VVTYTVLGGIKAVTWSDVQQMGVIFAGLVISLVTVIVLLPHSVSFGDAVFLAGAAGRLNAVTTNFDWNDRFNLWSGLIGG
TFLFLSYFGCDQSQVQRYLTGRSIAQSRLSLLFNAVAKIPMQFFILFIGAMVFVFYLFVQPPLLFQQAELKRIGRQSEFA
PMSEQYDRAFEQRKRAALALVEAHHAGDAAGEARQRAEYRAAQGELDAARRSASKLVEQTGGEKGFNDTNYIFLSFVTKY
LPSGVVGLVIAVIFAATMSASSGEINSLATVSVIDIYQRHFRRGQSDHHYLMASRWLTLFWGVYAVVFAGWARRLGSLIV
AVNKVGSLFYGSLLGCFALAILFPRVRGTAVFTGMILGEAAIFATAWFTDVSWLWYNVIGCAVVMVTALIITYASPGTTF
ARPDTQAQE
>Mature_568_residues
TTLDWFVLVLALVSIIAYGLYRSRGSDTVDRYLLAGKSMPWYAMALSIMATQASAITFISTTGQSYIDGMRFVQFYFGLP
LAMVVICATVVPMFHHARVYTAYEYLEKRFDTKTRALGSIIFLCQRGLSAGLTIYAPALVLSVILGWPERMTTILMGATV
VTYTVLGGIKAVTWSDVQQMGVIFAGLVISLVTVIVLLPHSVSFGDAVFLAGAAGRLNAVTTNFDWNDRFNLWSGLIGGT
FLFLSYFGCDQSQVQRYLTGRSIAQSRLSLLFNAVAKIPMQFFILFIGAMVFVFYLFVQPPLLFQQAELKRIGRQSEFAP
MSEQYDRAFEQRKRAALALVEAHHAGDAAGEARQRAEYRAAQGELDAARRSASKLVEQTGGEKGFNDTNYIFLSFVTKYL
PSGVVGLVIAVIFAATMSASSGEINSLATVSVIDIYQRHFRRGQSDHHYLMASRWLTLFWGVYAVVFAGWARRLGSLIVA
VNKVGSLFYGSLLGCFALAILFPRVRGTAVFTGMILGEAAIFATAWFTDVSWLWYNVIGCAVVMVTALIITYASPGTTFA
RPDTQAQE

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI167466278, Length=278, Percent_Identity=34.5323741007194, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4507035, Length=308, Percent_Identity=30.8441558441558, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI256985183, Length=315, Percent_Identity=32.0634920634921, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI157671931, Length=274, Percent_Identity=28.4671532846715, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI109659839, Length=574, Percent_Identity=22.9965156794425, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI109659836, Length=289, Percent_Identity=26.2975778546713, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI206597483, Length=291, Percent_Identity=24.7422680412371, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI110835708, Length=315, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI17941285, Length=300, Percent_Identity=24.3333333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI14140236, Length=323, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790113, Length=297, Percent_Identity=24.5791245791246, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533094, Length=322, Percent_Identity=25.4658385093168, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32566512, Length=230, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115533096, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24651741, Length=315, Percent_Identity=30.1587301587302, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28573698, Length=317, Percent_Identity=30.2839116719243, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281362918, Length=300, Percent_Identity=29.6666666666667, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24651739, Length=303, Percent_Identity=29.042904290429, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24641117, Length=302, Percent_Identity=29.1390728476821, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161076631, Length=282, Percent_Identity=29.0780141843972, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI221459584, Length=284, Percent_Identity=26.7605633802817, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI19920916, Length=277, Percent_Identity=27.4368231046931, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221459582, Length=298, Percent_Identity=24.496644295302, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574994, Length=297, Percent_Identity=28.2828282828283, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24645928, Length=302, Percent_Identity=27.1523178807947, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281364280, Length=276, Percent_Identity=25.7246376811594, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24640370, Length=242, Percent_Identity=25.6198347107438, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24650192, Length=278, Percent_Identity=26.978417266187, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362054, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281362052, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281362050, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24648056, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21356827, Length=315, Percent_Identity=26.031746031746, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221459588, Length=277, Percent_Identity=27.0758122743682, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221459586, Length=253, Percent_Identity=28.0632411067194, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221379702, Length=280, Percent_Identity=29.6428571428571, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 62707; Mature: 62576

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTLDWFVLVLALVSIIAYGLYRSRGSDTVDRYLLAGKSMPWYAMALSIMATQASAITFI
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEE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HHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]