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The map label for this gene is macB [H]

Identifier: 116620172

GI number: 116620172

Start: 1292061

End: 1294487

Strand: Reverse

Name: macB [H]

Synonym: Acid_1045

Alternate gene names: 116620172

Gene position: 1294487-1292061 (Counterclockwise)

Preceding gene: 116620174

Following gene: 116620169

Centisome position: 12.99

GC content: 63.41

Gene sequence:

>2427_bases
ATGCTGGATATTTTGCTTCAGGATATGCGCTACGGCCTGCGAACGCTGGCCAAGACTCCGACGTTCACGATTGTTGCCGT
GGTCTCCCTGGCCCTCGGCATCGGCGTGAACATTTCGATCTTCGGGTATCTCAATGCCGCGCTGTTCAAGCCTTTGGCGG
TAGAACGATCGGGCGAGTTGGTATCGCTCTACCACCGCAATGAAAAGGGGGCCGACGAGTTTTTCTCGAGCTCTTATCCG
GAATACGAGTTCTATCGCGAGCACAATACCGTCTTCTTCGGGATGCTCGCTTACCTGCGGATCCCGATGGTCATGGGAAG
CGGCGCAACTGCGCAGCAGATCTCGGGCGAATTGGTCAGCCCGGATTACTTTTCCGTGCTTGGTATCCATCCGTCAGCGG
GCCGATTCTTCAGCGGTGCGGAACACGATAGCGTGGCCGTGATCAGCGATGAACTATGGCGAGACCGTTTCGGCCGCACC
CCCGGGGCCATCGGGCAGACAATCCAAATCGGCACCGGGAAATTCACCGTCGTCGGAGTGGTGCCGGGGTCGTTTCGCGG
CATCGTGATGGACTGGACTGATCCACCCTCCCTCTGGGTTCCGGTCCAGCAGTATAAAGAGGCCACGCCCGTATTCCCGC
TCGATATCGTCCACTCCTGGGGAATGGAATCATACCTGGTGACGGCAAGACTGCGTCCGGGCGCGACCGCGGAGCAGGCC
AACGCTCAAATGGCAGCTCTGACTGCGCGGTTGCACGAACCGCAAGGCCGCCGGCAAGGGCAGCGTGCGGTCGTGTTCCC
TGTCCAATCGGCGCGCTTCTGGCCGAGTTACCGCGGGTCGATCGTGACCTTTCTGGGCGCTTTGATGACCATCGTCGGTG
TGATTCTGCTGATTGCATGTTGCAATCTGGCGAACCTGCTGGTGGCGCGCGCCACCAACAGGCGCCGTGAAATCGCCATG
CGACTGGTGCTCGGCGCCGGACGCATGCGCATTGCACGCCAGTTGCTGATCGAGAGCCTGCTGCTCGCTGCAATGGGAGG
CGCCGTTGCAATTGCCGTCGCCGCCTGGGCCACGGGCCGGTTGGTGCAATTCCATCGTGCCTTTCGGATTCCTCTGGCAA
TCGACACCGCCTGGGATGTTCGAATGCTGGCCTTTGCGATCGGCGTATCGGTCCTGACGGGTCTTCTGTTCGGCGCGGCT
CCGGTCGTCCAAACCTGGCGCACCGACCTGACGGATGCGTTGAAGTCGGGCGCGGCGGCAAGCGGCAATCCCCGCTCCCG
CCTGCGAAGCATTCTCCTCGTCGGCCAGGTCGCACTCTCCACCGTGTTGCTTTGCGGCGCAGGAATGTTCGTACGCACGC
TACACAATGCGCGGGCGCAGGACCCGACTTTGCATGCGGAGAACCTCCTCCTGGTCCAGCTGGAGCCAACATTGAATGGA
TATTCGGAGACCCGGGGGCAGAGGTTTTATGAAAACGTCTTGCGGCGCGTCCGCGCGATTCCCGGCGTCCGGAGCGCCGC
GCTGGTGGCATTGGTTCCATTTAGCGGACGTCGAGGCGGCACGAATATCTTCGCACCCGACCAGAGCCAGCAGCAGGTCG
ATTTCAACATCGTCTCCCCGGACTATTTTCAAACCACCGGGCTGGGGCTCCTGAACGGGCGGGAATTCACCGGGCGGGAT
AGCGGCGACGCACCCGCGGTAGCCGTGGTCAACGAGACTATGGCGGAGCGGTTTTGGCCCGGTGAAAATCCGCTGGGCAA
GCAACTGCGCACGGTCCGCCCGCCGCGAACGCTCACCGTGGTCGGGATGGTGCGCGACGGAAAGTTCCGCGGCTACCGCG
ACGAATTGCGCCCGGGTTTCTATGTGCCGGGCTCGCAGCAATATCGCGGGGCGATGACCCTGGAAGCCCGCACCGCGGGC
AACGCTGCGGCGTTCGGCGCCATCGTGCGTCGGGAGATCGCGGCCGTGGACGGCTCGATGCCGCTGACATCGGTCCTTAC
GATGGAAGCCCGGCTGGACGATGTCCTTTCCCAGGAACGGCTGATTGCCAGCTTCGCCTCGGGGCTGGGCCTGGTGGCGC
TGACGCTGGCGGCGATCGGGATCTACGGCGTGCTCTCCTTCGCGGTGGCGCGGCGTACCCGCGAGATCGGGATCCGCATG
GCGCTCGGAGCACGGCCATCGGAGATCTCGCGGATGGTCCTCCGCGAATCGGCCGCACTGGCGGCTTGCGGTTTCGCCAC
CGGTGGTGCCGGAGCCGTGATGCTGGCGCGGATGGCAAAGGCGCTCCTCTACGGCGTCGCACCCACAGATCCGGCAGCAT
TCGGACTGGCGCTTGGAATGTTGACGAGTGTGGCTTTGATCTCGGCGCTGATTCCGGCCTGGCGAGCCGCGCGCCTGGAT
CCCGCCACTACGCTACGCAGTGAATAG

Upstream 100 bases:

>100_bases
CCCCATCTTCGGCTGTCCCGCACGCAGTTGTTTCTTAAATTCCGCACCGCTGAGTGATTCGCTCATTCCGATCAGTATAC
TTTGGATTAGGATGGCGGCG

Downstream 100 bases:

>100_bases
GAAGGCCCTCTCGATCTAAGAGCACTCAAGGGGGTCCACGCGCGTAGCTCCGCGTGAAGGCGCACACGCCGCGCAGAAGG
TAACGGTGCCGAGCAGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MLDILLQDMRYGLRTLAKTPTFTIVAVVSLALGIGVNISIFGYLNAALFKPLAVERSGELVSLYHRNEKGADEFFSSSYP
EYEFYREHNTVFFGMLAYLRIPMVMGSGATAQQISGELVSPDYFSVLGIHPSAGRFFSGAEHDSVAVISDELWRDRFGRT
PGAIGQTIQIGTGKFTVVGVVPGSFRGIVMDWTDPPSLWVPVQQYKEATPVFPLDIVHSWGMESYLVTARLRPGATAEQA
NAQMAALTARLHEPQGRRQGQRAVVFPVQSARFWPSYRGSIVTFLGALMTIVGVILLIACCNLANLLVARATNRRREIAM
RLVLGAGRMRIARQLLIESLLLAAMGGAVAIAVAAWATGRLVQFHRAFRIPLAIDTAWDVRMLAFAIGVSVLTGLLFGAA
PVVQTWRTDLTDALKSGAAASGNPRSRLRSILLVGQVALSTVLLCGAGMFVRTLHNARAQDPTLHAENLLLVQLEPTLNG
YSETRGQRFYENVLRRVRAIPGVRSAALVALVPFSGRRGGTNIFAPDQSQQQVDFNIVSPDYFQTTGLGLLNGREFTGRD
SGDAPAVAVVNETMAERFWPGENPLGKQLRTVRPPRTLTVVGMVRDGKFRGYRDELRPGFYVPGSQQYRGAMTLEARTAG
NAAAFGAIVRREIAAVDGSMPLTSVLTMEARLDDVLSQERLIASFASGLGLVALTLAAIGIYGVLSFAVARRTREIGIRM
ALGARPSEISRMVLRESAALAACGFATGGAGAVMLARMAKALLYGVAPTDPAAFGLALGMLTSVALISALIPAWRAARLD
PATTLRSE

Sequences:

>Translated_808_residues
MLDILLQDMRYGLRTLAKTPTFTIVAVVSLALGIGVNISIFGYLNAALFKPLAVERSGELVSLYHRNEKGADEFFSSSYP
EYEFYREHNTVFFGMLAYLRIPMVMGSGATAQQISGELVSPDYFSVLGIHPSAGRFFSGAEHDSVAVISDELWRDRFGRT
PGAIGQTIQIGTGKFTVVGVVPGSFRGIVMDWTDPPSLWVPVQQYKEATPVFPLDIVHSWGMESYLVTARLRPGATAEQA
NAQMAALTARLHEPQGRRQGQRAVVFPVQSARFWPSYRGSIVTFLGALMTIVGVILLIACCNLANLLVARATNRRREIAM
RLVLGAGRMRIARQLLIESLLLAAMGGAVAIAVAAWATGRLVQFHRAFRIPLAIDTAWDVRMLAFAIGVSVLTGLLFGAA
PVVQTWRTDLTDALKSGAAASGNPRSRLRSILLVGQVALSTVLLCGAGMFVRTLHNARAQDPTLHAENLLLVQLEPTLNG
YSETRGQRFYENVLRRVRAIPGVRSAALVALVPFSGRRGGTNIFAPDQSQQQVDFNIVSPDYFQTTGLGLLNGREFTGRD
SGDAPAVAVVNETMAERFWPGENPLGKQLRTVRPPRTLTVVGMVRDGKFRGYRDELRPGFYVPGSQQYRGAMTLEARTAG
NAAAFGAIVRREIAAVDGSMPLTSVLTMEARLDDVLSQERLIASFASGLGLVALTLAAIGIYGVLSFAVARRTREIGIRM
ALGARPSEISRMVLRESAALAACGFATGGAGAVMLARMAKALLYGVAPTDPAAFGLALGMLTSVALISALIPAWRAARLD
PATTLRSE
>Mature_808_residues
MLDILLQDMRYGLRTLAKTPTFTIVAVVSLALGIGVNISIFGYLNAALFKPLAVERSGELVSLYHRNEKGADEFFSSSYP
EYEFYREHNTVFFGMLAYLRIPMVMGSGATAQQISGELVSPDYFSVLGIHPSAGRFFSGAEHDSVAVISDELWRDRFGRT
PGAIGQTIQIGTGKFTVVGVVPGSFRGIVMDWTDPPSLWVPVQQYKEATPVFPLDIVHSWGMESYLVTARLRPGATAEQA
NAQMAALTARLHEPQGRRQGQRAVVFPVQSARFWPSYRGSIVTFLGALMTIVGVILLIACCNLANLLVARATNRRREIAM
RLVLGAGRMRIARQLLIESLLLAAMGGAVAIAVAAWATGRLVQFHRAFRIPLAIDTAWDVRMLAFAIGVSVLTGLLFGAA
PVVQTWRTDLTDALKSGAAASGNPRSRLRSILLVGQVALSTVLLCGAGMFVRTLHNARAQDPTLHAENLLLVQLEPTLNG
YSETRGQRFYENVLRRVRAIPGVRSAALVALVPFSGRRGGTNIFAPDQSQQQVDFNIVSPDYFQTTGLGLLNGREFTGRD
SGDAPAVAVVNETMAERFWPGENPLGKQLRTVRPPRTLTVVGMVRDGKFRGYRDELRPGFYVPGSQQYRGAMTLEARTAG
NAAAFGAIVRREIAAVDGSMPLTSVLTMEARLDDVLSQERLIASFASGLGLVALTLAAIGIYGVLSFAVARRTREIGIRM
ALGARPSEISRMVLRESAALAACGFATGGAGAVMLARMAKALLYGVAPTDPAAFGLALGMLTSVALISALIPAWRAARLD
PATTLRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=283, Percent_Identity=25.4416961130742, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 87157; Mature: 87157

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDILLQDMRYGLRTLAKTPTFTIVAVVSLALGIGVNISIFGYLNAALFKPLAVERSGEL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCHHCCCCCCE
VSLYHRNEKGADEFFSSSYPEYEFYREHNTVFFGMLAYLRIPMVMGSGATAQQISGELVS
EEEEECCCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC
PDYFSVLGIHPSAGRFFSGAEHDSVAVISDELWRDRFGRTPGAIGQTIQIGTGKFTVVGV
CCCEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEE
VPGSFRGIVMDWTDPPSLWVPVQQYKEATPVFPLDIVHSWGMESYLVTARLRPGATAEQA
CCCCCCEEEEECCCCCCEEECHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCHHHH
NAQMAALTARLHEPQGRRQGQRAVVFPVQSARFWPSYRGSIVTFLGALMTIVGVILLIAC
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CNLANLLVARATNRRREIAMRLVLGAGRMRIARQLLIESLLLAAMGGAVAIAVAAWATGR
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
LVQFHRAFRIPLAIDTAWDVRMLAFAIGVSVLTGLLFGAAPVVQTWRTDLTDALKSGAAA
HHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
SGNPRSRLRSILLVGQVALSTVLLCGAGMFVRTLHNARAQDPTLHAENLLLVQLEPTLNG
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCC
YSETRGQRFYENVLRRVRAIPGVRSAALVALVPFSGRRGGTNIFAPDQSQQQVDFNIVSP
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
DYFQTTGLGLLNGREFTGRDSGDAPAVAVVNETMAERFWPGENPLGKQLRTVRPPRTLTV
CCHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEE
VGMVRDGKFRGYRDELRPGFYVPGSQQYRGAMTLEARTAGNAAAFGAIVRREIAAVDGSM
EEEEECCCCCCCHHHCCCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
PLTSVLTMEARLDDVLSQERLIASFASGLGLVALTLAAIGIYGVLSFAVARRTREIGIRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
ALGARPSEISRMVLRESAALAACGFATGGAGAVMLARMAKALLYGVAPTDPAAFGLALGM
EECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTSVALISALIPAWRAARLDPATTLRSE
HHHHHHHHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure
MLDILLQDMRYGLRTLAKTPTFTIVAVVSLALGIGVNISIFGYLNAALFKPLAVERSGEL
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCHHCCCCCCE
VSLYHRNEKGADEFFSSSYPEYEFYREHNTVFFGMLAYLRIPMVMGSGATAQQISGELVS
EEEEECCCCCHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC
PDYFSVLGIHPSAGRFFSGAEHDSVAVISDELWRDRFGRTPGAIGQTIQIGTGKFTVVGV
CCCEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEE
VPGSFRGIVMDWTDPPSLWVPVQQYKEATPVFPLDIVHSWGMESYLVTARLRPGATAEQA
CCCCCCEEEEECCCCCCEEECHHHHCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCHHHH
NAQMAALTARLHEPQGRRQGQRAVVFPVQSARFWPSYRGSIVTFLGALMTIVGVILLIAC
HHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
CNLANLLVARATNRRREIAMRLVLGAGRMRIARQLLIESLLLAAMGGAVAIAVAAWATGR
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCH
LVQFHRAFRIPLAIDTAWDVRMLAFAIGVSVLTGLLFGAAPVVQTWRTDLTDALKSGAAA
HHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
SGNPRSRLRSILLVGQVALSTVLLCGAGMFVRTLHNARAQDPTLHAENLLLVQLEPTLNG
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEECCCEEEEEECCCCCC
YSETRGQRFYENVLRRVRAIPGVRSAALVALVPFSGRRGGTNIFAPDQSQQQVDFNIVSP
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
DYFQTTGLGLLNGREFTGRDSGDAPAVAVVNETMAERFWPGENPLGKQLRTVRPPRTLTV
CCHHHCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEE
VGMVRDGKFRGYRDELRPGFYVPGSQQYRGAMTLEARTAGNAAAFGAIVRREIAAVDGSM
EEEEECCCCCCCHHHCCCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
PLTSVLTMEARLDDVLSQERLIASFASGLGLVALTLAAIGIYGVLSFAVARRTREIGIRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
ALGARPSEISRMVLRESAALAACGFATGGAGAVMLARMAKALLYGVAPTDPAAFGLALGM
EECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTSVALISALIPAWRAARLDPATTLRSE
HHHHHHHHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA