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The map label for this gene is yqaB [H]

Identifier: 116620118

GI number: 116620118

Start: 1233342

End: 1233965

Strand: Direct

Name: yqaB [H]

Synonym: Acid_0991

Alternate gene names: 116620118

Gene position: 1233342-1233965 (Clockwise)

Preceding gene: 116620110

Following gene: 116620120

Centisome position: 12.38

GC content: 62.98

Gene sequence:

>624_bases
ATGTCCGATCCGCAAGCCATTTTCTTCGATTTCGATGGTGTACTGCTTGACACCGAACCGGTGCATTGGGCCTGCTGGGC
GGACAGGCTCGCCACGCTTGACGTGACGCTCACGTGGGAGTATTACCGCGACTGTTGCATCGGTATCGACGACCGGGTGA
TGCTGCGTAATATCGCCTGCGAAGCCAAACCTGCGCGAGACTGGGAAACATTGTGGGCCCTCTATCCCGCGAAGAAAAAG
CTGTTCCAAGTGCGGATGACGACGCCACCGTTCGAGGCGGCGCTGGTGGATTTGCTGCCTGAACTGCGCCGGACTCACCG
GCTCGCGGTGGTCAGCTCCAGTTCGTGTTCCGAGATCGAACCGCTGCTGATATCAGCGGGGATCCGTGGTCACTTCGAGA
CCATCGTTGGAGGAGACGACGTGCAGCGCCACAAACCAGCTCCCGATCCGTACCTGCTAGCGGCGGAGCGTCTGGGCGTG
TCGCACGCGCTGGTGCTAGAAGATTCCGAGGCCGGATTGGCAAGCGGACGAGCCGCCGGCTTCGAGGTCCTGCGAGTGGG
GCACCCGTCGGAGGTCGTGGGGCTGCTGCGCCGGCGGCTCTCAGGCTCCGGCACCTCCGCCTGA

Upstream 100 bases:

>100_bases
TTCGGCGCGCAGGCGCTCGATCTCAGCTTGCATTTCTTCTTCTGTAGGCATGATCTTCAACTTCCTTGATACCACATGCT
ACGCTGAAGTTTCCCCACTT

Downstream 100 bases:

>100_bases
AGCGGTATTCTTGCGGCGCGCCGCGGCGCTTCGAGCCTGCCGGGATAGCGCCTTGTGGGACGCCGCCGATTGGCCTTCGC
GCTTCAACGCGTTGGTGGTT

Product: HAD family hydrolase

Products: beta-D-glucose 6-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSDPQAIFFDFDGVLLDTEPVHWACWADRLATLDVTLTWEYYRDCCIGIDDRVMLRNIACEAKPARDWETLWALYPAKKK
LFQVRMTTPPFEAALVDLLPELRRTHRLAVVSSSSCSEIEPLLISAGIRGHFETIVGGDDVQRHKPAPDPYLLAAERLGV
SHALVLEDSEAGLASGRAAGFEVLRVGHPSEVVGLLRRRLSGSGTSA

Sequences:

>Translated_207_residues
MSDPQAIFFDFDGVLLDTEPVHWACWADRLATLDVTLTWEYYRDCCIGIDDRVMLRNIACEAKPARDWETLWALYPAKKK
LFQVRMTTPPFEAALVDLLPELRRTHRLAVVSSSSCSEIEPLLISAGIRGHFETIVGGDDVQRHKPAPDPYLLAAERLGV
SHALVLEDSEAGLASGRAAGFEVLRVGHPSEVVGLLRRRLSGSGTSA
>Mature_206_residues
SDPQAIFFDFDGVLLDTEPVHWACWADRLATLDVTLTWEYYRDCCIGIDDRVMLRNIACEAKPARDWETLWALYPAKKKL
FQVRMTTPPFEAALVDLLPELRRTHRLAVVSSSSCSEIEPLLISAGIRGHFETIVGGDDVQRHKPAPDPYLLAAERLGVS
HALVLEDSEAGLASGRAAGFEVLRVGHPSEVVGLLRRRLSGSGTSA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates fructose 1-phosphate and 6-phosphogluconate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789046, Length=184, Percent_Identity=32.0652173913043, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010976
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 5.4.2.6

Molecular weight: Translated: 22884; Mature: 22753

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPQAIFFDFDGVLLDTEPVHWACWADRLATLDVTLTWEYYRDCCIGIDDRVMLRNIAC
CCCCCEEEEECCCEEECCCCCEEEEHHCCEEEEEEEEEEHHHHHHHCCCCCHHHHHHHCC
EAKPARDWETLWALYPAKKKLFQVRMTTPPFEAALVDLLPELRRTHRLAVVSSSSCSEIE
CCCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCC
PLLISAGIRGHFETIVGGDDVQRHKPAPDPYLLAAERLGVSHALVLEDSEAGLASGRAAG
CEEEECCCCCCEEEEECCCCHHHCCCCCCHHEEHHHHCCCEEEEEEECCCCCCCCCCCCC
FEVLRVGHPSEVVGLLRRRLSGSGTSA
EEEEEECCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDPQAIFFDFDGVLLDTEPVHWACWADRLATLDVTLTWEYYRDCCIGIDDRVMLRNIAC
CCCCEEEEECCCEEECCCCCEEEEHHCCEEEEEEEEEEHHHHHHHCCCCCHHHHHHHCC
EAKPARDWETLWALYPAKKKLFQVRMTTPPFEAALVDLLPELRRTHRLAVVSSSSCSEIE
CCCCCCCHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCC
PLLISAGIRGHFETIVGGDDVQRHKPAPDPYLLAAERLGVSHALVLEDSEAGLASGRAAG
CEEEECCCCCCEEEEECCCCHHHCCCCCCHHEEHHHHCCCEEEEEEECCCCCCCCCCCCC
FEVLRVGHPSEVVGLLRRRLSGSGTSA
EEEEEECCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-D-glucose 1-phosphate

Specific reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]