BacMap

Definition	Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome.
Accession	NC_008536
Length	9,965,640

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The map label for this gene is yqjQ [H]

Identifier: 116620116

GI number: 116620116

Start: 1232255

End: 1233040

Strand: Reverse

Name: yqjQ [H]

Synonym: Acid_0989

Alternate gene names: 116620116

Gene position: 1233040-1232255 (Counterclockwise)

Preceding gene: 116620117

Following gene: 116620115

Centisome position: 12.37

GC content: 62.85

Gene sequence:

>786_bases
ATGGCGAAGGGGATGGCCCTGATCACCGGAGCATCCAGCGGGATCGGGGCCGAACTCGCACGTCTGTGCGCGGCGGATGG
CTATGGTCTCATTCTGGTCGCACGCCGCACCGACCGCCTCGAGCAGTTGGGCGCGGAACTCGCCGCCGCTCACAATGTTA
AATTTCGTACGATCGCGGCTGACCTTGCCGAGCCCGATGCCGCCACGGCCATTTATCGGCAGACCAGCGGCGATACTATA
GACATCCTGATCAACAACGCAGGCTTCGGCTTGCGCGGCCGCTACGATCAAACCGAGTGGAATGCCGAAGCGCGCCTGAT
TCAGGTGAACATCACCGCGCTCGCGCAACTCACAAAGTCGTACGTGAAGGATATGGTGCGTCGCGGCTCTGGGCGCATCC
TCAACGTCGGGTCCACCGCGGCCTTCGTACCCGGACCGCTGATGGCGATGTACTACGCCAGCAAAGCCTTCGTGGTCTCC
TTCTCGGAAGCGCTCGCCAAGGAATTCGAGGGCACCGGCGTCACCGTGACGGTGTTGTGTCCCGGCCCCACCCGGACGGA
ATTCGACGCCGCAGCGGGAATCACGGACAGCAAGCTCTTCCGCGGCTCCGCAATGACTGCGCAGGAAGTCGCGCAGATCG
GCTATCGAGCGATGATGGCCGGCCAGGCCGAAGTGATCGCCGGAGCGCGCAATCGTTGGATGATCCTATCGACCCGCCTG
GCGCCGCGCACCATGCTTGCCGCGATCGCAAAACGGTTGAATTCCAGCGAGCATTCGGTACAATAG

Upstream 100 bases:

>100_bases
ATACCGGGAGCAATGGGAGAAGCTGCTGGCGATGTCCGACCAGATCCGCGAATTCATTCAAGCCAACGACGACAAGCTGA
AAAAGAAGGAATAGCAGGCC

Downstream 100 bases:

>100_bases
CCTGAAGGATTTTCATCCTTACTAGGCCCTTTTCTCCCATGGAACACGCATTCGACGATGGCGGAGTTCGCGGCGTACTG
CACCTTCCCGAGAAGCCCAC

Product: short-chain dehydrogenase/reductase SDR

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAKGMALITGASSGIGAELARLCAADGYGLILVARRTDRLEQLGAELAAAHNVKFRTIAADLAEPDAATAIYRQTSGDTI
DILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTKSYVKDMVRRGSGRILNVGSTAAFVPGPLMAMYYASKAFVVS
FSEALAKEFEGTGVTVTVLCPGPTRTEFDAAAGITDSKLFRGSAMTAQEVAQIGYRAMMAGQAEVIAGARNRWMILSTRL
APRTMLAAIAKRLNSSEHSVQ

Sequences:

>Translated_261_residues
MAKGMALITGASSGIGAELARLCAADGYGLILVARRTDRLEQLGAELAAAHNVKFRTIAADLAEPDAATAIYRQTSGDTI
DILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTKSYVKDMVRRGSGRILNVGSTAAFVPGPLMAMYYASKAFVVS
FSEALAKEFEGTGVTVTVLCPGPTRTEFDAAAGITDSKLFRGSAMTAQEVAQIGYRAMMAGQAEVIAGARNRWMILSTRL
APRTMLAAIAKRLNSSEHSVQ
>Mature_260_residues
AKGMALITGASSGIGAELARLCAADGYGLILVARRTDRLEQLGAELAAAHNVKFRTIAADLAEPDAATAIYRQTSGDTID
ILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTKSYVKDMVRRGSGRILNVGSTAAFVPGPLMAMYYASKAFVVSF
SEALAKEFEGTGVTVTVLCPGPTRTEFDAAAGITDSKLFRGSAMTAQEVAQIGYRAMMAGQAEVIAGARNRWMILSTRLA
PRTMLAAIAKRLNSSEHSVQ

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=33.695652173913, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI4557649, Length=183, Percent_Identity=34.9726775956284, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=33.5, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=33.5078534031414, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI223718074, Length=264, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=28.6458333333333, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI32483357, Length=196, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=255, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI157739938, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40254992, Length=183, Percent_Identity=26.775956284153, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI44680136, Length=182, Percent_Identity=25.8241758241758, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI44680133, Length=182, Percent_Identity=25.8241758241758, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI17738292, Length=182, Percent_Identity=25.8241758241758, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI119392083, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=219, Percent_Identity=30.1369863013699, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=186, Percent_Identity=34.4086021505376, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=32.620320855615, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=29.3814432989691, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367365, Length=191, Percent_Identity=32.9842931937173, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788459, Length=199, Percent_Identity=26.6331658291457, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790717, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789208, Length=186, Percent_Identity=26.3440860215054, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=193, Percent_Identity=32.6424870466321, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=194, Percent_Identity=32.9896907216495, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25152911, Length=185, Percent_Identity=30.2702702702703, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=202, Percent_Identity=28.2178217821782, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=31, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=230, Percent_Identity=29.5652173913043, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=246, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=29, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=245, Percent_Identity=28.1632653061224, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=185, Percent_Identity=27.5675675675676, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=238, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=201, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=31.3432835820896, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17557668, Length=215, Percent_Identity=25.1162790697674, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=198, Percent_Identity=29.7979797979798, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=185, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=239, Percent_Identity=31.7991631799163, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=33.1632653061224, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=33.1632653061224, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=31.5508021390374, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=31.5508021390374, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24640442, Length=187, Percent_Identity=28.8770053475936, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=34.5360824742268, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=31.1224489795918, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24584752, Length=191, Percent_Identity=31.413612565445, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=31.1827956989247, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24641388, Length=214, Percent_Identity=33.6448598130841, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=34.010152284264, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=190, Percent_Identity=32.1052631578947, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644339, Length=199, Percent_Identity=30.6532663316583, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=31.6326530612245, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648693, Length=202, Percent_Identity=30.6930693069307, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355889, Length=202, Percent_Identity=30.6930693069307, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007234, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI23397609, Length=203, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639444, Length=188, Percent_Identity=31.9148936170213, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641232, Length=223, Percent_Identity=27.8026905829596, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24651139, Length=271, Percent_Identity=25.830258302583, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24663911, Length=194, Percent_Identity=30.4123711340206, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=227, Percent_Identity=23.7885462555066, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007232, Length=188, Percent_Identity=30.3191489361702, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=29.4416243654822, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27768; Mature: 27637

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGMALITGASSGIGAELARLCAADGYGLILVARRTDRLEQLGAELAAAHNVKFRTIAA
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEH
DLAEPDAATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTKS
HHCCCCHHHHEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
YVKDMVRRGSGRILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAKEFEGTGVTVTVLC
HHHHHHHCCCCCEEEECCCCEECCCHHHHHHHHCHHHEEEHHHHHHHHHCCCCEEEEEEE
PGPTRTEFDAAAGITDSKLFRGSAMTAQEVAQIGYRAMMAGQAEVIAGARNRWMILSTRL
CCCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCEEEEEECC
APRTMLAAIAKRLNSSEHSVQ
CHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKGMALITGASSGIGAELARLCAADGYGLILVARRTDRLEQLGAELAAAHNVKFRTIAA
CCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEH
DLAEPDAATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTKS
HHCCCCHHHHEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHH
YVKDMVRRGSGRILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAKEFEGTGVTVTVLC
HHHHHHHCCCCCEEEECCCCEECCCHHHHHHHHCHHHEEEHHHHHHHHHCCCCEEEEEEE
PGPTRTEFDAAAGITDSKLFRGSAMTAQEVAQIGYRAMMAGQAEVIAGARNRWMILSTRL
CCCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHEEECCCCCEEEEEECC
APRTMLAAIAKRLNSSEHSVQ
CHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]