Click here to switch to the map view.

The map label for this gene is frr [H]

Identifier: 116620031

GI number: 116620031

Start: 1132865

End: 1133470

Strand: Reverse

Name: frr [H]

Synonym: Acid_0903

Alternate gene names: 116620031

Gene position: 1133470-1132865 (Counterclockwise)

Preceding gene: 116620032

Following gene: 116620030

Centisome position: 11.37

GC content: 57.1

Gene sequence:

>606_bases
ATGAAGACAGAACAGCCTGCAGCAACCACCGGTCCTGCATTCACCTCGGTGAAGGAAGTCGAGGCGAACCTCAAGACCCG
AATGGAAAAGGCGGTCTCGGATCTGCAGCACGAAATGGCATCGATCCGCACTGGCCGCGCCACGCTGAGCCTCCTGGACC
ACATACGTGTGGATTATTACGGCACGCCAACGCCGCTCAACCAGGTTGCCAACCTGCACGTTCCCGAGCCGAACCTGATC
ACGATCCAGCCCTGGGATGTCTCGCAAATCGGCACGATCGAGAAATCGATTCGCACCAGCGACCTGGGGTTGAATCCAGC
CAACGACGGGAAGGTCATTCGCCTGCCAATACCACCCCTAACCGAAGAACGCCGCAAGGAACTCGTCAAAAAGCTGCATG
CCGCGGCCGAACACCATCGGGTGGCGGTGCGCAACATCCGCCGCGACGGCAACGAGGCCGTGAAGAAGCTGTCCAAAGAC
AAAAAGATCACGGAAGACGACGACAAAAAGGCCCATGACGAGATCCAGAAGCTGACCGATCTGTACATGGGCAAAGTCGA
TACCGCGGCTAAGACCAAAGAAAAAGAGATCATGGAAATCCGCTAG

Upstream 100 bases:

>100_bases
TTCAATTTGAACACGATAGGAAATATAATGCGTATGTCGATGGGTGAGACTATCGGCACCGTGATTCACTAGCAGCACCA
GAGCACGGAGAGACTTCGCT

Downstream 100 bases:

>100_bases
CCGCGAGGCCCGGAGATCCATCTTGGGATTCGTTGATCGCTCGTTCGCCCCGCCGGCGCGAGCCGCAGCCGACCCGTTAT
GAGTGCGTCCAATTCATGGT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKTEQPAATTGPAFTSVKEVEANLKTRMEKAVSDLQHEMASIRTGRATLSLLDHIRVDYYGTPTPLNQVANLHVPEPNLI
TIQPWDVSQIGTIEKSIRTSDLGLNPANDGKVIRLPIPPLTEERRKELVKKLHAAAEHHRVAVRNIRRDGNEAVKKLSKD
KKITEDDDKKAHDEIQKLTDLYMGKVDTAAKTKEKEIMEIR

Sequences:

>Translated_201_residues
MKTEQPAATTGPAFTSVKEVEANLKTRMEKAVSDLQHEMASIRTGRATLSLLDHIRVDYYGTPTPLNQVANLHVPEPNLI
TIQPWDVSQIGTIEKSIRTSDLGLNPANDGKVIRLPIPPLTEERRKELVKKLHAAAEHHRVAVRNIRRDGNEAVKKLSKD
KKITEDDDKKAHDEIQKLTDLYMGKVDTAAKTKEKEIMEIR
>Mature_201_residues
MKTEQPAATTGPAFTSVKEVEANLKTRMEKAVSDLQHEMASIRTGRATLSLLDHIRVDYYGTPTPLNQVANLHVPEPNLI
TIQPWDVSQIGTIEKSIRTSDLGLNPANDGKVIRLPIPPLTEERRKELVKKLHAAAEHHRVAVRNIRRDGNEAVKKLSKD
KKITEDDDKKAHDEIQKLTDLYMGKVDTAAKTKEKEIMEIR

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=48.9130434782609, Blast_Score=186, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 22612; Mature: 22612

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEQPAATTGPAFTSVKEVEANLKTRMEKAVSDLQHEMASIRTGRATLSLLDHIRVDYY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GTPTPLNQVANLHVPEPNLITIQPWDVSQIGTIEKSIRTSDLGLNPANDGKVIRLPIPPL
CCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
TEERRKELVKKLHAAAEHHRVAVRNIRRDGNEAVKKLSKDKKITEDDDKKAHDEIQKLTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LYMGKVDTAAKTKEKEIMEIR
HHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTEQPAATTGPAFTSVKEVEANLKTRMEKAVSDLQHEMASIRTGRATLSLLDHIRVDYY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GTPTPLNQVANLHVPEPNLITIQPWDVSQIGTIEKSIRTSDLGLNPANDGKVIRLPIPPL
CCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCC
TEERRKELVKKLHAAAEHHRVAVRNIRRDGNEAVKKLSKDKKITEDDDKKAHDEIQKLTD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LYMGKVDTAAKTKEKEIMEIR
HHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA