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The map label for this gene is aroK [H]

Identifier: 116619905

GI number: 116619905

Start: 976333

End: 976863

Strand: Direct

Name: aroK [H]

Synonym: Acid_0777

Alternate gene names: 116619905

Gene position: 976333-976863 (Clockwise)

Preceding gene: 116619904

Following gene: 116619906

Centisome position: 9.8

GC content: 64.41

Gene sequence:

>531_bases
ATGATTCTCAAACTCAAACGCACTCCCGGGATTTACGTGGTCGGCTTCATGGGCGCTGGCAAGAGCACGGTCGGCCGCCA
CCTGGCGCACCACCTGGGCTGGAGTTTTTTCGATAGCGATGAGGAGATCGAGCGCGCCGAAAAGGCGTCGATCGCCAGCA
TCTTCGAAGAGCGCGGCGAGGCCGAGTTCCGGCGTATTGAAACCGAAATCATCCGGCAGCACGTAGGCTGGATTGAACGC
GGGCGTCCGGCGGTGCTGGCGCTCGGTGGGGGAGCCTACGCGCAGCCGGCAAATCGCCAGTTGCTGGAGAACAACGGCAT
CACGGTGTGGCTGGATTGTCCCTTTGAACTGGTACAGCAGCGCGTGGCGCAGGCCACTCACCGGCCGCTGGCGCGCGATC
CCGAGGCCTTTGCGGCTCTCTACCACGCGCGCCGCGCCGATTACGGGCGTGCCGCGGTGCAAGTCGTGATCGAGAGCGAC
GACCCGGACGTCACCGTCGGCGCCATTCTCGGACACCCCGAATTCCGATGA

Upstream 100 bases:

>100_bases
GCACGATAGTCACTCCGCGCTCCGGGTGGCTCCTCGTATTGGCCATGCGGCTGTTTCCCGCGCTGGTGGAGGCGCGCATG
GCGCGGATCAACGGGACAGC

Downstream 100 bases:

>100_bases
GTGGGCTCCGGACCCTGCGCCGCCACGCAGCCGCGATCTTCCGCGCGTCGCTCCAGGCGGCCGACCCCGCAGGCGCCGTG
GAACGCCACCTGGCGAGGTG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MILKLKRTPGIYVVGFMGAGKSTVGRHLAHHLGWSFFDSDEEIERAEKASIASIFEERGEAEFRRIETEIIRQHVGWIER
GRPAVLALGGGAYAQPANRQLLENNGITVWLDCPFELVQQRVAQATHRPLARDPEAFAALYHARRADYGRAAVQVVIESD
DPDVTVGAILGHPEFR

Sequences:

>Translated_176_residues
MILKLKRTPGIYVVGFMGAGKSTVGRHLAHHLGWSFFDSDEEIERAEKASIASIFEERGEAEFRRIETEIIRQHVGWIER
GRPAVLALGGGAYAQPANRQLLENNGITVWLDCPFELVQQRVAQATHRPLARDPEAFAALYHARRADYGRAAVQVVIESD
DPDVTVGAILGHPEFR
>Mature_176_residues
MILKLKRTPGIYVVGFMGAGKSTVGRHLAHHLGWSFFDSDEEIERAEKASIASIFEERGEAEFRRIETEIIRQHVGWIER
GRPAVLALGGGAYAQPANRQLLENNGITVWLDCPFELVQQRVAQATHRPLARDPEAFAALYHARRADYGRAAVQVVIESD
DPDVTVGAILGHPEFR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=163, Percent_Identity=36.1963190184049, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1786587, Length=171, Percent_Identity=28.0701754385965, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19626; Mature: 19626

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKLKRTPGIYVVGFMGAGKSTVGRHLAHHLGWSFFDSDEEIERAEKASIASIFEERGE
CEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCH
AEFRRIETEIIRQHVGWIERGRPAVLALGGGAYAQPANRQLLENNGITVWLDCPFELVQQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEECCHHHHHH
RVAQATHRPLARDPEAFAALYHARRADYGRAAVQVVIESDDPDVTVGAILGHPEFR
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MILKLKRTPGIYVVGFMGAGKSTVGRHLAHHLGWSFFDSDEEIERAEKASIASIFEERGE
CEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCH
AEFRRIETEIIRQHVGWIERGRPAVLALGGGAYAQPANRQLLENNGITVWLDCPFELVQQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCCCEEEEEECCHHHHHH
RVAQATHRPLARDPEAFAALYHARRADYGRAAVQVVIESDDPDVTVGAILGHPEFR
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA