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The map label for this gene is yprA [H]

Identifier: 116619897

GI number: 116619897

Start: 966106

End: 968466

Strand: Direct

Name: yprA [H]

Synonym: Acid_0769

Alternate gene names: 116619897

Gene position: 966106-968466 (Clockwise)

Preceding gene: 116619896

Following gene: 116619899

Centisome position: 9.69

GC content: 63.36

Gene sequence:

>2361_bases
ATGAATCTCTCCCTCGGTTTTCCGGGTTTTTCCAAAGAACTCGCAGTCACCCCAAAGCAATCGCTGGAGGCGGTTGTCTC
CTATTTCCGCTCCGCGCACAAGGAGCCCGATTCCGCAGTGCGTGCCATTCACCACCAGCCGGCGTCCGAAGGCGAGTTCT
CGGAAATGCCCGCCGCGGTGGATAGCCGCCTTCGCGCCGCCCTGGCGAAGCGCGGCATCGAGCGCCTCTACACCCATCAG
GCCGACGCCTTCGACCAGATTCAGGCCGGTAAGCACGTAGTCATCGTGACCCCTACGGCAAGCGGCAAGACCCTGTGCTA
CAACCTGCCGGTGCTCAACCTTCTGCTGCGCGACGAGGGCGCGCGCGCGATGTACCTCTTCCCCACCAAGGCGCTGGCCG
AGGATCAGCTCCACGAGTTCCAGGGCGCGGTGGAAGAAATGGGCAGCGAAATTCGCGCCTTCACGTATGATGGCGATACC
CCGCAGGATGCGCGCCGCGCCATCCGCTCCCGCGCCAACGTCGTGCTCACCAATCCCGACATGCTGCATAGCGGGATTCT
GCCGCATCACACGCGCTGGGCGCGCTACTTCGAGAATCTCCGCTACATAGTCATCGATGAGCTGCACTATTATCGCGGCG
TGTATGGCAGCCACCTCGCCAACCTGCTCCGGCGCCTCAGCCGCATCTGCGAGTTCTATAATTCCAAGCCGCAATTCATC
TGCTGCAGCGCCACCATCGCCAACCCGAAGGAACTGGCGGAAGCGCTCACCGGCGAGCCCTTCGAGCTGGTGGAGCGCAA
CGGCGCACCGCGCGGCGAGAAGTTTTTCATCTTCTATAATCCGCCAGTGGTCAACAGGCAGCTCGGCATCCGCCGCAGCT
ATATCGCCGAGACGCGCCGCATGGCGCTGAAGTTCATCGAGAATAATCTGCAGACCCTGGTCTTCGCCAACAACCGCCTG
GCCACCGAAGTTTTGGTGACTTACCTGAAGGACGCCTGCGATCGCGGCCCGATTCCCAGCGAAACCGTACGCGGCTACCG
CGGCGGCTATCTGCCGCGCGAGCGCCGCGAGATCGAGCAGAGCCTGCGCGCCGGTAAGATCCGCGCCGTGGTGGCGACCA
ATGCGCTCGAACTCGGTATCGACATCGGCTCGCTGGACGCCGTGGTCATGGCCGGCTATCCGGGAACCATCGCCTCGAGC
TGGCAGCGCGCCGGCCGCGCCGGACGCCGGCAGAGCACCTCGGCCGCGGTCATGGTGGCCTCCAGCGCACCGCTCGATCA
GTACATTGTGGAGCACCCCGATTACTTCTTCGGACGTTCTCCGGAGCATGCCTATATCAATCCCGAGAATCTGGAGATCT
TCCTGGCGCACCTGAAGTGCGCCGCCTTCGAACTTCCCCTGCGCGACGACGAAAAGTTCGGGCGCCACGATCTCGCCGAG
ATCTGCCGCTACCTGGAGGAAGCCGGATTCCTGCACCACTCCGCCGCCGCCTGGCACTGGACCAGCGACACGTACCCGGC
CGACGCCACCAGTTTGCGCTCCGTGACCAGCGATAATTTCGTGGTGGTGGATATTACCGGCGAAGCCAAAGTGATCGCCG
AGGTCTCCTTCCCCACCGCGCTCACCACGCTCCACGAAAAGGCCATCTACCTTCACGAAGCGCGCCAGTTCCACGTGGAG
CGCTTCGACTACGACCAGCGCAAGGCCTACGTCAAGAGCGTGGATTGCGATTACTACACCGACGCGATCGATTACACGCA
GGTCAAGGTGCTCGAAGAGATGGAAGGCGAGCCGCAGAACGGTGCGCGCCGCTTGCATGGCGACGTCCGCGTCACGCGCC
AGATCGTCGGCTTCAAGAAGATCAAGTTCTACACCATGGAAAACGTCGGCGCTGGCAAGCTCAATATGCCGGAGCAGGAG
ATGCACACCACAGCGTTCTGGCTGCACTTTCCCGCGGCCTTCCTGGCGCGCTTTGCCGAGTTCACTCCCACCGAAAAGCA
GAGCGGGATTTCGGGACTCGGGAACGCGCTCCGCACCGTGGCCTCATTGCTGTTGATGTGCGATCCGCGGGATCTCGGTG
TGGCGCTGAGTGAAGAGATCGCCGGCGGCCTCGAAGCCTTCGAACCCAATCTCTACCTTTACGACAACTACCCCGGCGGT
ATCGGCCAGAGCGGGCCGCTTTACCGCCTGGCTCCCCAGTTGCTGCGCCAGACTGCCGGCCTGCTGGCGGCCTGCGCCTG
CGAAGCGGGCTGCCCCTCCTGTGTCGGCCCGAGCGGCGAGACGGGTGAACGCGGCAAGCTGGTGGCTGCGCGAATTCTGG
CGGAGCTGATGGGAACGGCAGAGCAGATTACCGCGGCTTGA

Upstream 100 bases:

>100_bases
ATTACCGACAGCTCCTTAACAGTCGCGGCTCCGATCATTGAGCGCTTGTCACCGGGCCACTTTCGTTGTAAGGTAGCAAA
GAAAAGGCGAAAGCGGCTCA

Downstream 100 bases:

>100_bases
GCTGCTCTGGCAGGGCGGCGTACCCTTCGGGCGGCGGGTAGAGCGAAATCAATAGTTCCAGGCGTCGGCGAAGATAGCGG
CTCGGCATCTGGCGCGGGCC

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 786; Mature: 786

Protein sequence:

>786_residues
MNLSLGFPGFSKELAVTPKQSLEAVVSYFRSAHKEPDSAVRAIHHQPASEGEFSEMPAAVDSRLRAALAKRGIERLYTHQ
ADAFDQIQAGKHVVIVTPTASGKTLCYNLPVLNLLLRDEGARAMYLFPTKALAEDQLHEFQGAVEEMGSEIRAFTYDGDT
PQDARRAIRSRANVVLTNPDMLHSGILPHHTRWARYFENLRYIVIDELHYYRGVYGSHLANLLRRLSRICEFYNSKPQFI
CCSATIANPKELAEALTGEPFELVERNGAPRGEKFFIFYNPPVVNRQLGIRRSYIAETRRMALKFIENNLQTLVFANNRL
ATEVLVTYLKDACDRGPIPSETVRGYRGGYLPRERREIEQSLRAGKIRAVVATNALELGIDIGSLDAVVMAGYPGTIASS
WQRAGRAGRRQSTSAAVMVASSAPLDQYIVEHPDYFFGRSPEHAYINPENLEIFLAHLKCAAFELPLRDDEKFGRHDLAE
ICRYLEEAGFLHHSAAAWHWTSDTYPADATSLRSVTSDNFVVVDITGEAKVIAEVSFPTALTTLHEKAIYLHEARQFHVE
RFDYDQRKAYVKSVDCDYYTDAIDYTQVKVLEEMEGEPQNGARRLHGDVRVTRQIVGFKKIKFYTMENVGAGKLNMPEQE
MHTTAFWLHFPAAFLARFAEFTPTEKQSGISGLGNALRTVASLLLMCDPRDLGVALSEEIAGGLEAFEPNLYLYDNYPGG
IGQSGPLYRLAPQLLRQTAGLLAACACEAGCPSCVGPSGETGERGKLVAARILAELMGTAEQITAA

Sequences:

>Translated_786_residues
MNLSLGFPGFSKELAVTPKQSLEAVVSYFRSAHKEPDSAVRAIHHQPASEGEFSEMPAAVDSRLRAALAKRGIERLYTHQ
ADAFDQIQAGKHVVIVTPTASGKTLCYNLPVLNLLLRDEGARAMYLFPTKALAEDQLHEFQGAVEEMGSEIRAFTYDGDT
PQDARRAIRSRANVVLTNPDMLHSGILPHHTRWARYFENLRYIVIDELHYYRGVYGSHLANLLRRLSRICEFYNSKPQFI
CCSATIANPKELAEALTGEPFELVERNGAPRGEKFFIFYNPPVVNRQLGIRRSYIAETRRMALKFIENNLQTLVFANNRL
ATEVLVTYLKDACDRGPIPSETVRGYRGGYLPRERREIEQSLRAGKIRAVVATNALELGIDIGSLDAVVMAGYPGTIASS
WQRAGRAGRRQSTSAAVMVASSAPLDQYIVEHPDYFFGRSPEHAYINPENLEIFLAHLKCAAFELPLRDDEKFGRHDLAE
ICRYLEEAGFLHHSAAAWHWTSDTYPADATSLRSVTSDNFVVVDITGEAKVIAEVSFPTALTTLHEKAIYLHEARQFHVE
RFDYDQRKAYVKSVDCDYYTDAIDYTQVKVLEEMEGEPQNGARRLHGDVRVTRQIVGFKKIKFYTMENVGAGKLNMPEQE
MHTTAFWLHFPAAFLARFAEFTPTEKQSGISGLGNALRTVASLLLMCDPRDLGVALSEEIAGGLEAFEPNLYLYDNYPGG
IGQSGPLYRLAPQLLRQTAGLLAACACEAGCPSCVGPSGETGERGKLVAARILAELMGTAEQITAA
>Mature_786_residues
MNLSLGFPGFSKELAVTPKQSLEAVVSYFRSAHKEPDSAVRAIHHQPASEGEFSEMPAAVDSRLRAALAKRGIERLYTHQ
ADAFDQIQAGKHVVIVTPTASGKTLCYNLPVLNLLLRDEGARAMYLFPTKALAEDQLHEFQGAVEEMGSEIRAFTYDGDT
PQDARRAIRSRANVVLTNPDMLHSGILPHHTRWARYFENLRYIVIDELHYYRGVYGSHLANLLRRLSRICEFYNSKPQFI
CCSATIANPKELAEALTGEPFELVERNGAPRGEKFFIFYNPPVVNRQLGIRRSYIAETRRMALKFIENNLQTLVFANNRL
ATEVLVTYLKDACDRGPIPSETVRGYRGGYLPRERREIEQSLRAGKIRAVVATNALELGIDIGSLDAVVMAGYPGTIASS
WQRAGRAGRRQSTSAAVMVASSAPLDQYIVEHPDYFFGRSPEHAYINPENLEIFLAHLKCAAFELPLRDDEKFGRHDLAE
ICRYLEEAGFLHHSAAAWHWTSDTYPADATSLRSVTSDNFVVVDITGEAKVIAEVSFPTALTTLHEKAIYLHEARQFHVE
RFDYDQRKAYVKSVDCDYYTDAIDYTQVKVLEEMEGEPQNGARRLHGDVRVTRQIVGFKKIKFYTMENVGAGKLNMPEQE
MHTTAFWLHFPAAFLARFAEFTPTEKQSGISGLGNALRTVASLLLMCDPRDLGVALSEEIAGGLEAFEPNLYLYDNYPGG
IGQSGPLYRLAPQLLRQTAGLLAACACEAGCPSCVGPSGETGERGKLVAARILAELMGTAEQITAA

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI284005309, Length=376, Percent_Identity=24.468085106383, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI40217847, Length=387, Percent_Identity=23.2558139534884, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1787942, Length=381, Percent_Identity=28.0839895013123, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320497, Length=721, Percent_Identity=34.3966712898752, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI9755332, Length=391, Percent_Identity=21.9948849104859, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 87474; Mature: 87474

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSLGFPGFSKELAVTPKQSLEAVVSYFRSAHKEPDSAVRAIHHQPASEGEFSEMPAAV
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCHHH
DSRLRAALAKRGIERLYTHQADAFDQIQAGKHVVIVTPTASGKTLCYNLPVLNLLLRDEG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHEECCC
ARAMYLFPTKALAEDQLHEFQGAVEEMGSEIRAFTYDGDTPQDARRAIRSRANVVLTNPD
CCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCH
MLHSGILPHHTRWARYFENLRYIVIDELHYYRGVYGSHLANLLRRLSRICEFYNSKPQFI
HHHCCCCCCHHHHHHHHHCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEE
CCSATIANPKELAEALTGEPFELVERNGAPRGEKFFIFYNPPVVNRQLGIRRSYIAETRR
EEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCCCHHHCHHHHHHHHHHH
MALKFIENNLQTLVFANNRLATEVLVTYLKDACDRGPIPSETVRGYRGGYLPRERREIEQ
HHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHH
SLRAGKIRAVVATNALELGIDIGSLDAVVMAGYPGTIASSWQRAGRAGRRQSTSAAVMVA
HHHHCCEEEEEEECHHEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEE
SSAPLDQYIVEHPDYFFGRSPEHAYINPENLEIFLAHLKCAAFELPLRDDEKFGRHDLAE
CCCCHHHHHHCCCCHHCCCCCCCCEECCCCCEEHEEHHHHHHEECCCCCCHHCCHHHHHH
ICRYLEEAGFLHHSAAAWHWTSDTYPADATSLRSVTSDNFVVVDITGEAKVIAEVSFPTA
HHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCCHH
LTTLHEKAIYLHEARQFHVERFDYDQRKAYVKSVDCDYYTDAIDYTQVKVLEEMEGEPQN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCCCC
GARRLHGDVRVTRQIVGFKKIKFYTMENVGAGKLNMPEQEMHTTAFWLHFPAAFLARFAE
CHHHHHHHHHHHHHHHCHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FTPTEKQSGISGLGNALRTVASLLLMCDPRDLGVALSEEIAGGLEAFEPNLYLYDNYPGG
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCHHHCCCCEEEEECCCCC
IGQSGPLYRLAPQLLRQTAGLLAACACEAGCPSCVGPSGETGERGKLVAARILAELMGTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
EQITAA
HHHHCC
>Mature Secondary Structure
MNLSLGFPGFSKELAVTPKQSLEAVVSYFRSAHKEPDSAVRAIHHQPASEGEFSEMPAAV
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHCCHHH
DSRLRAALAKRGIERLYTHQADAFDQIQAGKHVVIVTPTASGKTLCYNLPVLNLLLRDEG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHEECCC
ARAMYLFPTKALAEDQLHEFQGAVEEMGSEIRAFTYDGDTPQDARRAIRSRANVVLTNPD
CCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCH
MLHSGILPHHTRWARYFENLRYIVIDELHYYRGVYGSHLANLLRRLSRICEFYNSKPQFI
HHHCCCCCCHHHHHHHHHCCEEEEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEE
CCSATIANPKELAEALTGEPFELVERNGAPRGEKFFIFYNPPVVNRQLGIRRSYIAETRR
EEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCCEEEEEECCCCCCHHHCHHHHHHHHHHH
MALKFIENNLQTLVFANNRLATEVLVTYLKDACDRGPIPSETVRGYRGGYLPRERREIEQ
HHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHH
SLRAGKIRAVVATNALELGIDIGSLDAVVMAGYPGTIASSWQRAGRAGRRQSTSAAVMVA
HHHHCCEEEEEEECHHEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEE
SSAPLDQYIVEHPDYFFGRSPEHAYINPENLEIFLAHLKCAAFELPLRDDEKFGRHDLAE
CCCCHHHHHHCCCCHHCCCCCCCCEECCCCCEEHEEHHHHHHEECCCCCCHHCCHHHHHH
ICRYLEEAGFLHHSAAAWHWTSDTYPADATSLRSVTSDNFVVVDITGEAKVIAEVSFPTA
HHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEEECCCHH
LTTLHEKAIYLHEARQFHVERFDYDQRKAYVKSVDCDYYTDAIDYTQVKVLEEMEGEPQN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCCCC
GARRLHGDVRVTRQIVGFKKIKFYTMENVGAGKLNMPEQEMHTTAFWLHFPAAFLARFAE
CHHHHHHHHHHHHHHHCHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FTPTEKQSGISGLGNALRTVASLLLMCDPRDLGVALSEEIAGGLEAFEPNLYLYDNYPGG
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCHHHCCCCEEEEECCCCC
IGQSGPLYRLAPQLLRQTAGLLAACACEAGCPSCVGPSGETGERGKLVAARILAELMGTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
EQITAA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]