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The map label for this gene is dan [H]

Identifier: 116619882

GI number: 116619882

Start: 949990

End: 951678

Strand: Direct

Name: dan [H]

Synonym: Acid_0754

Alternate gene names: 116619882

Gene position: 949990-951678 (Clockwise)

Preceding gene: 116619881

Following gene: 116619887

Centisome position: 9.53

GC content: 64.83

Gene sequence:

>1689_bases
ATGGGCCTCATGTTTCGTGGAATCCTGATTCTTCTAGCATGCGCGTCGGTGTGTGGCGCGCAGGAATACGACCTCGTCAT
CAGCGGCGGTCGGGTGGTGGATGGGTCGGGCAACCCGTGGTTCCTGGGCGATGTAGCGGTGCGCGGAGACCGGATCGTGC
GCATTACTCCCGCGGGGATGTTGCGCGAGGCGGCGGCGAAGCAGCGCATCGACGCGCGCGGGCTGGTGGTGGCGCCGGGC
TTCATCGATATTCAAGGCGCCTCGCAAGGGCCGCTGCTGGCGGGCGATGGGCGCGTGATCAGCCACGTCGCACAGGGCAT
CACGACGGAGATCATGGGCGAAGGCTGGACGGCCGCGCCTTCCAACGAGAAGACGCTGGAATCGATGCAGAGCTTGGGGC
GCGCCGGAGCAGCGCCGCGCTTCGACGGTCCGCACGGGTTCGAAGCATGGCTGCGCGCGATGGAAGAGCACGGGGCGTCG
CTGAATTTCGGATCGTTCGTGGGCGCGGCGACGGTGCGGCAGTATGTGAAGGGAATGCAGGAGGGAGAGGCCACGGCGGC
GGAATTGGAGCAGATGCAGGCGCTGGTGCGCAACGCGATGCTGGACGGCGCGTTCGGCGTAGCCAGCGCGTTGATCTATC
CGCCTGGCAATTATGCGGGAACTCGCGAGCTGGCGGGGATTTCGAAGGCGATGTCACCGTACGGCGGCATCTACATCACG
CACATGCGCAGCGAGGCCGACCACTTCACCGAGAGCATCGCGGAGGCGCTCGAGATCGGCCGAGAGGCGGGCGTGCCGGT
CGAGATCTACCACTTAAAAGCGGCGGGCCGGCGCAATTGGGCAAAGATGGGCGAGGCCATCGCGCTGATCGAGAAGGCGC
GGCGCGCGGGGCAGGACGCCGGCGCGGACATGTACCCATACACCGCGGGCGCCACCGGGCTGACCGCCTGTTTTCCCCCG
TGGACCGCCGCCGATGGGAAGCTCTTTGACAATCTGGCGGACCCTGCGGTGCGGGCGAAAATTCGGGCCGAGATGGGCCA
GCCCGTCACCGAGTGGGAGAACATGGGGCAACTCGCGGGGCCTGAGAATATCTTGATCGTATCGTTGAACCAGCCGCAGA
ACCAGGCCTTCGCCGGCAAGCGGCTGGCCGAGATCGCCAAGCTGCAAAACAAGGACTGGCGCGATGCGGCCATGGACCTC
GTGCTGACCGAACACCGGCGCGTAGAGACGATCTATTTCCTGATGAGCGAGGACAACCTGGCGCTCCAGTTGAAGCTGCC
GTGGATCAAGATCGGCACCGACAGTGTGGGCTTAAATCCGGAGAACGCGAAAGACCTGACGCATCCGCGATCGTACGGCA
CGTTTCCCAGGATCCTCGGCGAGTTCGTGCGCGAGAAGAAGGTGATGCCGCTCGAGGAGGCTGTGCGCAAGATGACCTCG
GCCACCGCGCGGCGCCTATCCATCCCGGACCGAGGCCTGCTGCAGGCCGGGACGTTCGCGGACGTGGTGATCTTCGATGC
CAACACGATCGGTGACAGCGCCACCTACGAAAAGCCGCACCAGCTGCCAACGGGAATCAAGTACGTGATCGTGAACGGCA
CGATCGTAATGAAGGAAGGTGTACACACGGGCGCGAAGCCCGGCAAAGTGGTGCGGGGTCCGGGCTGGGTGCAGTCAGAA
TTGAAGTAG

Upstream 100 bases:

>100_bases
ATAAACTCGCAAGTCCTTCGGCCATTCCGACGATTGCGATTTCACACTCCTAAGTCCTATTCAGGATAGATCACTGTGGC
CGGCGGAGTGGCCTTCTATA

Downstream 100 bases:

>100_bases
GGCCGGAACGTCTACCGAAGTGCTGATGAGCCCGCTTTCATAGATGCCGGTGACGCGCAGGGCGGAGTCCTTGCGGAATA
GGGTCATGCTGGCGGTCTTC

Product: dihydroorotase

Products: NA

Alternate protein names: N-acyl-D-amino-acid deacylase [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MGLMFRGILILLACASVCGAQEYDLVISGGRVVDGSGNPWFLGDVAVRGDRIVRITPAGMLREAAAKQRIDARGLVVAPG
FIDIQGASQGPLLAGDGRVISHVAQGITTEIMGEGWTAAPSNEKTLESMQSLGRAGAAPRFDGPHGFEAWLRAMEEHGAS
LNFGSFVGAATVRQYVKGMQEGEATAAELEQMQALVRNAMLDGAFGVASALIYPPGNYAGTRELAGISKAMSPYGGIYIT
HMRSEADHFTESIAEALEIGREAGVPVEIYHLKAAGRRNWAKMGEAIALIEKARRAGQDAGADMYPYTAGATGLTACFPP
WTAADGKLFDNLADPAVRAKIRAEMGQPVTEWENMGQLAGPENILIVSLNQPQNQAFAGKRLAEIAKLQNKDWRDAAMDL
VLTEHRRVETIYFLMSEDNLALQLKLPWIKIGTDSVGLNPENAKDLTHPRSYGTFPRILGEFVREKKVMPLEEAVRKMTS
ATARRLSIPDRGLLQAGTFADVVIFDANTIGDSATYEKPHQLPTGIKYVIVNGTIVMKEGVHTGAKPGKVVRGPGWVQSE
LK

Sequences:

>Translated_562_residues
MGLMFRGILILLACASVCGAQEYDLVISGGRVVDGSGNPWFLGDVAVRGDRIVRITPAGMLREAAAKQRIDARGLVVAPG
FIDIQGASQGPLLAGDGRVISHVAQGITTEIMGEGWTAAPSNEKTLESMQSLGRAGAAPRFDGPHGFEAWLRAMEEHGAS
LNFGSFVGAATVRQYVKGMQEGEATAAELEQMQALVRNAMLDGAFGVASALIYPPGNYAGTRELAGISKAMSPYGGIYIT
HMRSEADHFTESIAEALEIGREAGVPVEIYHLKAAGRRNWAKMGEAIALIEKARRAGQDAGADMYPYTAGATGLTACFPP
WTAADGKLFDNLADPAVRAKIRAEMGQPVTEWENMGQLAGPENILIVSLNQPQNQAFAGKRLAEIAKLQNKDWRDAAMDL
VLTEHRRVETIYFLMSEDNLALQLKLPWIKIGTDSVGLNPENAKDLTHPRSYGTFPRILGEFVREKKVMPLEEAVRKMTS
ATARRLSIPDRGLLQAGTFADVVIFDANTIGDSATYEKPHQLPTGIKYVIVNGTIVMKEGVHTGAKPGKVVRGPGWVQSE
LK
>Mature_561_residues
GLMFRGILILLACASVCGAQEYDLVISGGRVVDGSGNPWFLGDVAVRGDRIVRITPAGMLREAAAKQRIDARGLVVAPGF
IDIQGASQGPLLAGDGRVISHVAQGITTEIMGEGWTAAPSNEKTLESMQSLGRAGAAPRFDGPHGFEAWLRAMEEHGASL
NFGSFVGAATVRQYVKGMQEGEATAAELEQMQALVRNAMLDGAFGVASALIYPPGNYAGTRELAGISKAMSPYGGIYITH
MRSEADHFTESIAEALEIGREAGVPVEIYHLKAAGRRNWAKMGEAIALIEKARRAGQDAGADMYPYTAGATGLTACFPPW
TAADGKLFDNLADPAVRAKIRAEMGQPVTEWENMGQLAGPENILIVSLNQPQNQAFAGKRLAEIAKLQNKDWRDAAMDLV
LTEHRRVETIYFLMSEDNLALQLKLPWIKIGTDSVGLNPENAKDLTHPRSYGTFPRILGEFVREKKVMPLEEAVRKMTSA
TARRLSIPDRGLLQAGTFADVVIFDANTIGDSATYEKPHQLPTGIKYVIVNGTIVMKEGVHTGAKPGKVVRGPGWVQSEL
K

Specific function: Has a wide specificity; hydrolyzes N-acyl derivative of neutral D-amino acids [H]

COG id: COG3653

COG function: function code Q; N-acyl-D-aspartate/D-glutamate deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acyl-D-amino-acid deacylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR023100
- InterPro:   IPR012855
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3; PF07908 D-aminoacyl_C [H]

EC number: =3.5.1.81 [H]

Molecular weight: Translated: 60480; Mature: 60349

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLMFRGILILLACASVCGAQEYDLVISGGRVVDGSGNPWFLGDVAVRGDRIVRITPAGM
CCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCEEEEEEEECCCEEEEECCHHH
LREAAAKQRIDARGLVVAPGFIDIQGASQGPLLAGDGRVISHVAQGITTEIMGEGWTAAP
HHHHHHHHCCCCCCEEEECCEEEECCCCCCCEEECCCHHHHHHHHCHHHHHHCCCCCCCC
SNEKTLESMQSLGRAGAAPRFDGPHGFEAWLRAMEEHGASLNFGSFVGAATVRQYVKGMQ
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EGEATAAELEQMQALVRNAMLDGAFGVASALIYPPGNYAGTRELAGISKAMSPYGGIYIT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCEEEE
HMRSEADHFTESIAEALEIGREAGVPVEIYHLKAAGRRNWAKMGEAIALIEKARRAGQDA
EECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
GADMYPYTAGATGLTACFPPWTAADGKLFDNLADPAVRAKIRAEMGQPVTEWENMGQLAG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
PENILIVSLNQPQNQAFAGKRLAEIAKLQNKDWRDAAMDLVLTEHRRVETIYFLMSEDNL
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCE
ALQLKLPWIKIGTDSVGLNPENAKDLTHPRSYGTFPRILGEFVREKKVMPLEEAVRKMTS
EEEEEECEEEECCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ATARRLSIPDRGLLQAGTFADVVIFDANTIGDSATYEKPHQLPTGIKYVIVNGTIVMKEG
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECEEEEECC
VHTGAKPGKVVRGPGWVQSELK
CCCCCCCCCEEECCCCHHCCCC
>Mature Secondary Structure 
GLMFRGILILLACASVCGAQEYDLVISGGRVVDGSGNPWFLGDVAVRGDRIVRITPAGM
CHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCEEEEEEEECCCEEEEECCHHH
LREAAAKQRIDARGLVVAPGFIDIQGASQGPLLAGDGRVISHVAQGITTEIMGEGWTAAP
HHHHHHHHCCCCCCEEEECCEEEECCCCCCCEEECCCHHHHHHHHCHHHHHHCCCCCCCC
SNEKTLESMQSLGRAGAAPRFDGPHGFEAWLRAMEEHGASLNFGSFVGAATVRQYVKGMQ
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EGEATAAELEQMQALVRNAMLDGAFGVASALIYPPGNYAGTRELAGISKAMSPYGGIYIT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCEEEE
HMRSEADHFTESIAEALEIGREAGVPVEIYHLKAAGRRNWAKMGEAIALIEKARRAGQDA
EECCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCC
GADMYPYTAGATGLTACFPPWTAADGKLFDNLADPAVRAKIRAEMGQPVTEWENMGQLAG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
PENILIVSLNQPQNQAFAGKRLAEIAKLQNKDWRDAAMDLVLTEHRRVETIYFLMSEDNL
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCE
ALQLKLPWIKIGTDSVGLNPENAKDLTHPRSYGTFPRILGEFVREKKVMPLEEAVRKMTS
EEEEEECEEEECCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ATARRLSIPDRGLLQAGTFADVVIFDANTIGDSATYEKPHQLPTGIKYVIVNGTIVMKEG
HHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECEEEEECC
VHTGAKPGKVVRGPGWVQSELK
CCCCCCCCCEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8541651 [H]