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The map label for this gene is yidJ [H]

Identifier: 116619845

GI number: 116619845

Start: 895751

End: 897187

Strand: Direct

Name: yidJ [H]

Synonym: Acid_0717

Alternate gene names: 116619845

Gene position: 895751-897187 (Clockwise)

Preceding gene: 116619844

Following gene: 116619846

Centisome position: 8.99

GC content: 63.4

Gene sequence:

>1437_bases
TTGGCATCTGAAAAACAGACCAGGCGGCAATGGCTGAGCGCATCCGCCGCCGCGGCGGTAGCTTCCTCGGCCGCCGCACA
AACCACCCCTGGAACGGCCCGCCCTAACGTTCTCCTCATCATCTCCGACCAGTTCCGATGGGATTGCATCGGCGCCATGG
GGCTCAACCCCATGAACCTTACGCCAAACCTGGACGGCATGGCCTCGCGCGGCGTGCTCTTCCGTTCCGCGATTTCCAAT
CAGCCGGTCTGTGCTCCCGCGCGTGCCAGCATCTTCACCGGCCAGTACCCCAGCCGTCACGGCGTGTGGCGCAATGGACT
CGGGCTCGCCGCGAACGCGGTGACGCTGGGCAGCGCCATGAAGCAGGCCGGCTACTCCACCAACTACATCGGCAAGTGGC
ATCTCTCCCCCGGCGCGGCCGACACTCCGGAAACCCGGGGCCCGGTCAAGCCGGAGAATCGCGGCGGATTTCAAGATCTG
TGGGAAGCCGCCAACGTTCTGGAACTGACCTCGCACGCCTATGAGGGCGATCTCTTCGACGGCGATGGCAAGCCTCTCCA
TTTCTCCAACCGATACCGCGCCGATTTCATGACCGATCGCGCGCAGCTCTTTCTCCGCTCCCGCGCTGCCCGATCGCCCT
TCCTGCTGACCCTCTCCTATCTCGAAGTCCACCATCAGAACGACAAGGACACTTTCGACCCGCCCAAGGAATTCGCCGGC
CGCTATCCCAACCCGTTCGTCCCGCAGGATCTGCGTCCGCTGCCCGGAACCTGGCCCAGCCAGCTCGCCGACTACTTCGC
CTGTGTCGCGAAGATGGATGAGATCGTGGGCACGCTGCGCAAGACGCTGGTGGAAACCGGGTTGGATAAGAATACGATCG
TGATGTTCACCAGCGATCACGGCAACCACTTCCGCACCCGCAACGCCGAGTACAAACGCAGCCCGCACGAGAGCTCCATC
CACATCCCGCTGGTGATGGAAGGCCCGGGCTTCAATCGCGGAATGGAAGTCAATCAACTCGTGAGCCACGTGGATATGGC
GCCGACGCTGCTCGCTGCCGCCGGGCTTGAGGTTCCTGCCTCGATGCAGGGCCACAATTTTCTCCCCCTGCTGGATCGCC
ATACCGAAGGCTGGCGCGACGAGGTCTACTTCGAAATGTCGGAGTTCGTCACCGGCCGCGGCCTGCGGACTCCGCAGTAT
ACCTACGCCGCCGCCGCGCCCAAGGTCCCGGGCTGGAAAGCCACTCCCACCGTGGATAAGTTCGTGGAATACATGCTCTA
CGACCTGTATTCCGACCCCTATCAGCAGGTGAACCTGGCAGGCCGCACGCCTTATCAGAAGGTTGCCGCCGAACTGCGGC
AGCGCCTGCAAGCCCGCATGCGGGAAGCCAGCGGTGAGCGATCCACCATCGACCCTGCGTGGTTCCCCTACTCGTAG

Upstream 100 bases:

>100_bases
TCAACGTGGGCAGTGAGCTGCGCCGCCGCACCTCGGCACGGGTCAAGTAGCACTGAAAACCAGCGGCGCCAGATGATAGA
CTCTCGGCTCGGAGGACATT

Downstream 100 bases:

>100_bases
CGCCGGCAGGCGTATGGGGAGCGCGATCCGAATTCTGCTGATGGCGCTGCACGCGGCGGCGCTGACTGCGCTTTGGGCGC
TGTTCCCCCCGCCGGGGAGT

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MASEKQTRRQWLSASAAAAVASSAAAQTTPGTARPNVLLIISDQFRWDCIGAMGLNPMNLTPNLDGMASRGVLFRSAISN
QPVCAPARASIFTGQYPSRHGVWRNGLGLAANAVTLGSAMKQAGYSTNYIGKWHLSPGAADTPETRGPVKPENRGGFQDL
WEAANVLELTSHAYEGDLFDGDGKPLHFSNRYRADFMTDRAQLFLRSRAARSPFLLTLSYLEVHHQNDKDTFDPPKEFAG
RYPNPFVPQDLRPLPGTWPSQLADYFACVAKMDEIVGTLRKTLVETGLDKNTIVMFTSDHGNHFRTRNAEYKRSPHESSI
HIPLVMEGPGFNRGMEVNQLVSHVDMAPTLLAAAGLEVPASMQGHNFLPLLDRHTEGWRDEVYFEMSEFVTGRGLRTPQY
TYAAAAPKVPGWKATPTVDKFVEYMLYDLYSDPYQQVNLAGRTPYQKVAAELRQRLQARMREASGERSTIDPAWFPYS

Sequences:

>Translated_478_residues
MASEKQTRRQWLSASAAAAVASSAAAQTTPGTARPNVLLIISDQFRWDCIGAMGLNPMNLTPNLDGMASRGVLFRSAISN
QPVCAPARASIFTGQYPSRHGVWRNGLGLAANAVTLGSAMKQAGYSTNYIGKWHLSPGAADTPETRGPVKPENRGGFQDL
WEAANVLELTSHAYEGDLFDGDGKPLHFSNRYRADFMTDRAQLFLRSRAARSPFLLTLSYLEVHHQNDKDTFDPPKEFAG
RYPNPFVPQDLRPLPGTWPSQLADYFACVAKMDEIVGTLRKTLVETGLDKNTIVMFTSDHGNHFRTRNAEYKRSPHESSI
HIPLVMEGPGFNRGMEVNQLVSHVDMAPTLLAAAGLEVPASMQGHNFLPLLDRHTEGWRDEVYFEMSEFVTGRGLRTPQY
TYAAAAPKVPGWKATPTVDKFVEYMLYDLYSDPYQQVNLAGRTPYQKVAAELRQRLQARMREASGERSTIDPAWFPYS
>Mature_477_residues
ASEKQTRRQWLSASAAAAVASSAAAQTTPGTARPNVLLIISDQFRWDCIGAMGLNPMNLTPNLDGMASRGVLFRSAISNQ
PVCAPARASIFTGQYPSRHGVWRNGLGLAANAVTLGSAMKQAGYSTNYIGKWHLSPGAADTPETRGPVKPENRGGFQDLW
EAANVLELTSHAYEGDLFDGDGKPLHFSNRYRADFMTDRAQLFLRSRAARSPFLLTLSYLEVHHQNDKDTFDPPKEFAGR
YPNPFVPQDLRPLPGTWPSQLADYFACVAKMDEIVGTLRKTLVETGLDKNTIVMFTSDHGNHFRTRNAEYKRSPHESSIH
IPLVMEGPGFNRGMEVNQLVSHVDMAPTLLAAAGLEVPASMQGHNFLPLLDRHTEGWRDEVYFEMSEFVTGRGLRTPQYT
YAAAAPKVPGWKATPTVDKFVEYMLYDLYSDPYQQVNLAGRTPYQKVAAELRQRLQARMREASGERSTIDPAWFPYS

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI39930577, Length=495, Percent_Identity=26.6666666666667, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI240255478, Length=469, Percent_Identity=25.5863539445629, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI240255483, Length=469, Percent_Identity=25.5863539445629, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI29789100, Length=469, Percent_Identity=25.5863539445629, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4504061, Length=490, Percent_Identity=25.5102040816327, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI189571643, Length=423, Percent_Identity=23.8770685579196, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI189571641, Length=423, Percent_Identity=23.8770685579196, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI189571638, Length=423, Percent_Identity=23.8770685579196, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI189571636, Length=423, Percent_Identity=23.8770685579196, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4503899, Length=402, Percent_Identity=27.6119402985075, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI146229331, Length=458, Percent_Identity=25.9825327510917, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI146229329, Length=458, Percent_Identity=25.9825327510917, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI6005990, Length=458, Percent_Identity=25.9825327510917, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI146229324, Length=458, Percent_Identity=25.9825327510917, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI58743319, Length=436, Percent_Identity=24.3119266055046, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI59797060, Length=482, Percent_Identity=24.2738589211618, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI45430057, Length=510, Percent_Identity=24.7058823529412, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI38569405, Length=347, Percent_Identity=25.0720461095101, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI38569407, Length=347, Percent_Identity=25.0720461095101, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI109389362, Length=502, Percent_Identity=22.9083665338645, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI157266309, Length=138, Percent_Identity=36.9565217391304, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI53831991, Length=114, Percent_Identity=38.5964912280702, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI31742482, Length=138, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI71852586, Length=117, Percent_Identity=35.042735042735, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI71852584, Length=112, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI1790112, Length=367, Percent_Identity=33.2425068119891, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI87081924, Length=347, Percent_Identity=27.6657060518732, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790233, Length=361, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17568795, Length=410, Percent_Identity=26.3414634146341, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19922168, Length=522, Percent_Identity=27.2030651340996, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24653364, Length=522, Percent_Identity=27.0114942528736, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366397, Length=345, Percent_Identity=28.1159420289855, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281366395, Length=345, Percent_Identity=28.1159420289855, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24666163, Length=345, Percent_Identity=28.1159420289855, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647401, Length=381, Percent_Identity=26.7716535433071, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24666109, Length=371, Percent_Identity=25.8760107816712, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24666175, Length=367, Percent_Identity=27.2479564032698, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281363223, Length=349, Percent_Identity=24.0687679083095, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 53106; Mature: 52975

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEKQTRRQWLSASAAAAVASSAAAQTTPGTARPNVLLIISDQFRWDCIGAMGLNPMNL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCC
TPNLDGMASRGVLFRSAISNQPVCAPARASIFTGQYPSRHGVWRNGLGLAANAVTLGSAM
CCCCCCHHHCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
KQAGYSTNYIGKWHLSPGAADTPETRGPVKPENRGGFQDLWEAANVLELTSHAYEGDLFD
HHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEC
GDGKPLHFSNRYRADFMTDRAQLFLRSRAARSPFLLTLSYLEVHHQNDKDTFDPPKEFAG
CCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCCHHHHCC
RYPNPFVPQDLRPLPGTWPSQLADYFACVAKMDEIVGTLRKTLVETGLDKNTIVMFTSDH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GNHFRTRNAEYKRSPHESSIHIPLVMEGPGFNRGMEVNQLVSHVDMAPTLLAAAGLEVPA
CCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SMQGHNFLPLLDRHTEGWRDEVYFEMSEFVTGRGLRTPQYTYAAAAPKVPGWKATPTVDK
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHCCCCCCCCCCCCCCHHH
FVEYMLYDLYSDPYQQVNLAGRTPYQKVAAELRQRLQARMREASGERSTIDPAWFPYS
HHHHHHHHHHCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASEKQTRRQWLSASAAAAVASSAAAQTTPGTARPNVLLIISDQFRWDCIGAMGLNPMNL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCC
TPNLDGMASRGVLFRSAISNQPVCAPARASIFTGQYPSRHGVWRNGLGLAANAVTLGSAM
CCCCCCHHHCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
KQAGYSTNYIGKWHLSPGAADTPETRGPVKPENRGGFQDLWEAANVLELTSHAYEGDLFD
HHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEC
GDGKPLHFSNRYRADFMTDRAQLFLRSRAARSPFLLTLSYLEVHHQNDKDTFDPPKEFAG
CCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCCCCCCHHHHCC
RYPNPFVPQDLRPLPGTWPSQLADYFACVAKMDEIVGTLRKTLVETGLDKNTIVMFTSDH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GNHFRTRNAEYKRSPHESSIHIPLVMEGPGFNRGMEVNQLVSHVDMAPTLLAAAGLEVPA
CCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
SMQGHNFLPLLDRHTEGWRDEVYFEMSEFVTGRGLRTPQYTYAAAAPKVPGWKATPTVDK
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEHCCCCCCCCCCCCCCHHH
FVEYMLYDLYSDPYQQVNLAGRTPYQKVAAELRQRLQARMREASGERSTIDPAWFPYS
HHHHHHHHHHCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Sulfuric ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]