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The map label for this gene is insF1 [C]

Identifier: 116619768

GI number: 116619768

Start: 796930

End: 797760

Strand: Direct

Name: insF1 [C]

Synonym: Acid_0635

Alternate gene names: 116619768

Gene position: 796930-797760 (Clockwise)

Preceding gene: 116619767

Following gene: 116619773

Centisome position: 8.0

GC content: 57.16

Gene sequence:

>831_bases
ATGACGATTCTGCGCATGTGTGAACTGGGCGACATCAGCCGGGCTGGCTTCTACCGGTTCGATCCGGAGGCGGAGCAGCG
CGAGGAAGAGTTGGACCTGCGCGACGCGATCCAGAGGATCGCTCTGGAATTCCCATGCTACGGTAGGCCCAGAATCACCG
CCGAGCTTCGGCGTCAGGGCTGGGCAGTGAATCATAAGCGGGTTGGACGCATCATGCGGGAAGACAACCTCCTTTGCATT
CGCCGGAGGAAGTTTGTTTGCTGCACCACCGATTCCAATCACGGCCTTCGCGTCTATCCCAACTTGGCCAAGAAGATGGA
GTTGACCGGGTTGGACCAGTTGTGGGTGGCCGACATCACCTACATTCGGCTGGAGACGGAGTTCATCTATCTGGCGGTGG
TGCTGGATGCATTCTCAAGACGGGTAATTGGCTGGGCTCTGGGCCGGACTCTGGAAGCTAGCCTGGCGGTGCAGGCGTTG
AAGATGGCTTTCCGGCGGCGGGGCTCCGTCAAAGGATTGACCCATCATTCCGATCGCGGCGTGCAATACGCTTCCAAGGA
ATACACGGATTTGCTGAAGGAACACGGCGTTCAGATCAGCATGAGCCGGAAGGGCAATCCCTACGACAATGCCAAATGCG
AATCCTTCATGAAGACCTTGAAATACGAGGAGGTCTATAGACAAGAATATCGCGACCTCGCCGAGGCGCAAGCGTCGGTG
GAAAAGTTCATTGAGAAAATCTACAACGGCAAGCGTCTGCACTCGGCGCTGGGCTACTGCTCGCCGGTCGAGTTTGAACG
TTCGCTGGTGCCGCTGGAGCAAACTGCATGA

Upstream 100 bases:

>100_bases
GGTGCTTGCAGCGCCTCGAGGAACAGCGGATGCTGCAGGCACTGACTGGAAAGCCGCGACCTGCCAGTACATCGAAGACC
AAATCCAGAAAGGCGTCCAG

Downstream 100 bases:

>100_bases
AAAGTGAGGGCGCCCTCAGAATGCGTTTTGGGAGGCATGACGGAATCTATCGGTCCGATGTGTCGTTCCTGCTTTTTACC
CCTGGGGGCGTGTCCCGCTT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTILRMCELGDISRAGFYRFDPEAEQREEELDLRDAIQRIALEFPCYGRPRITAELRRQGWAVNHKRVGRIMREDNLLCI
RRRKFVCCTTDSNHGLRVYPNLAKKMELTGLDQLWVADITYIRLETEFIYLAVVLDAFSRRVIGWALGRTLEASLAVQAL
KMAFRRRGSVKGLTHHSDRGVQYASKEYTDLLKEHGVQISMSRKGNPYDNAKCESFMKTLKYEEVYRQEYRDLAEAQASV
EKFIEKIYNGKRLHSALGYCSPVEFERSLVPLEQTA

Sequences:

>Translated_276_residues
MTILRMCELGDISRAGFYRFDPEAEQREEELDLRDAIQRIALEFPCYGRPRITAELRRQGWAVNHKRVGRIMREDNLLCI
RRRKFVCCTTDSNHGLRVYPNLAKKMELTGLDQLWVADITYIRLETEFIYLAVVLDAFSRRVIGWALGRTLEASLAVQAL
KMAFRRRGSVKGLTHHSDRGVQYASKEYTDLLKEHGVQISMSRKGNPYDNAKCESFMKTLKYEEVYRQEYRDLAEAQASV
EKFIEKIYNGKRLHSALGYCSPVEFERSLVPLEQTA
>Mature_275_residues
TILRMCELGDISRAGFYRFDPEAEQREEELDLRDAIQRIALEFPCYGRPRITAELRRQGWAVNHKRVGRIMREDNLLCIR
RRKFVCCTTDSNHGLRVYPNLAKKMELTGLDQLWVADITYIRLETEFIYLAVVLDAFSRRVIGWALGRTLEASLAVQALK
MAFRRRGSVKGLTHHSDRGVQYASKEYTDLLKEHGVQISMSRKGNPYDNAKCESFMKTLKYEEVYRQEYRDLAEAQASVE
KFIEKIYNGKRLHSALGYCSPVEFERSLVPLEQTA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=228, Percent_Identity=30.2631578947368, Blast_Score=111, Evalue=8e-25,
Organism=Escherichia coli, GI1788405, Length=272, Percent_Identity=37.1323529411765, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787263, Length=272, Percent_Identity=37.1323529411765, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786753, Length=272, Percent_Identity=37.1323529411765, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786570, Length=272, Percent_Identity=37.1323529411765, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786490, Length=272, Percent_Identity=37.1323529411765, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789981, Length=259, Percent_Identity=31.6602316602317, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790724, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789424, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789224, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788305, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787669, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786558, Length=262, Percent_Identity=27.8625954198473, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32086; Mature: 31955

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILRMCELGDISRAGFYRFDPEAEQREEELDLRDAIQRIALEFPCYGRPRITAELRRQG
CCHHHCCCCCCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHCC
WAVNHKRVGRIMREDNLLCIRRRKFVCCTTDSNHGLRVYPNLAKKMELTGLDQLWVADIT
CCCCHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEECCCHHHHHHHCCCCHHHHHHEE
YIRLETEFIYLAVVLDAFSRRVIGWALGRTLEASLAVQALKMAFRRRGSVKGLTHHSDRG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VQYASKEYTDLLKEHGVQISMSRKGNPYDNAKCESFMKTLKYEEVYRQEYRDLAEAQASV
CHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKFIEKIYNGKRLHSALGYCSPVEFERSLVPLEQTA
HHHHHHHHCCHHHHHHHCCCCCCCHHHHCCCHHCCC
>Mature Secondary Structure 
TILRMCELGDISRAGFYRFDPEAEQREEELDLRDAIQRIALEFPCYGRPRITAELRRQG
CHHHCCCCCCCCCCCCEECCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHCC
WAVNHKRVGRIMREDNLLCIRRRKFVCCTTDSNHGLRVYPNLAKKMELTGLDQLWVADIT
CCCCHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEECCCHHHHHHHCCCCHHHHHHEE
YIRLETEFIYLAVVLDAFSRRVIGWALGRTLEASLAVQALKMAFRRRGSVKGLTHHSDRG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VQYASKEYTDLLKEHGVQISMSRKGNPYDNAKCESFMKTLKYEEVYRQEYRDLAEAQASV
CHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKFIEKIYNGKRLHSALGYCSPVEFERSLVPLEQTA
HHHHHHHHCCHHHHHHHCCCCCCCHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]