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The map label for this gene is tolQ [H]

Identifier: 116619648

GI number: 116619648

Start: 622570

End: 623283

Strand: Direct

Name: tolQ [H]

Synonym: Acid_0509

Alternate gene names: 116619648

Gene position: 622570-623283 (Clockwise)

Preceding gene: 116619645

Following gene: 116619649

Centisome position: 6.25

GC content: 59.1

Gene sequence:

>714_bases
ATGTTAGATTTGAGATTAGGAGACGCATTGCTCTTCGAGACTCCCGTTGCCTTCCTCCTTCAGACAGATCTCTGGGATAT
GGTCCAGCACACAGGGCCCGCCGGTAAGGTGGTGCTTGTGGTTCTGGTCTTTTTTTCTGTTTCTTCCTGGACATTTATCT
TTTCCAAATTGAGCGCCCTGCGCGGCGCCCGTCAATCTAACGCACGCTTCCTGCGCGCTTTTCGCAAGTCCAGCGGCATG
GAAGCCGTGATGGTGGCGAGCGAGCAGTTCCGCCCCTCGCCGCTCGTCGCCGTCTTCGATTTCGGCTACGAAGAGCTGGA
GCGCCAGGTCAAATCGCGTGGCAGCATCGTCAACCGCACCGCGCTCGAACGCACCCTGCAACTCGGTGTCAACGAAGAAA
TCTCCAAGCTCGAGCGCAACATGAGCTGGCTCGCCACCACCGCCAGCGTCACCCCATTTATCGGGCTTCTCGGCACAGTC
CTCGGCATCATCCGCGCCTTCGAAGATCTCAGCCAGATGGGTTCCACCAGCATCAAAGCCATCGGACCCGGCATCGCCGA
GGCGCTCATCACCACCGCCGTCGGACTCTTCGCCGCCATTCCAGCGGCCGTCTTCTATAACTACTTCGGCCACGTCACTC
GCGAGATCGGCGCGCGCATGGACGATTTCGCCATGGAGTTCCTCAACATGGCCGACCGCAGCTTCGGAGAATAG

Upstream 100 bases:

>100_bases
GTGACGCAAAGAGAGCCCAAACAACTTCTGCTTTCTTTGCGTTACTCTGCGGCTCTGTGCCTCTGCGAGAACAGACTTTT
TCCGGACCCTCCGCGTCCTT

Downstream 100 bases:

>100_bases
TCGATGGCCTTCTCGATCAACAGCGGCGGCGGGTTGGGATCGCGCAGGCGGCACGGTTCTCCCGCGCTCTCCGAAATCAA
CGTCACGCCCTTCGTAGACG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MLDLRLGDALLFETPVAFLLQTDLWDMVQHTGPAGKVVLVVLVFFSVSSWTFIFSKLSALRGARQSNARFLRAFRKSSGM
EAVMVASEQFRPSPLVAVFDFGYEELERQVKSRGSIVNRTALERTLQLGVNEEISKLERNMSWLATTASVTPFIGLLGTV
LGIIRAFEDLSQMGSTSIKAIGPGIAEALITTAVGLFAAIPAAVFYNYFGHVTREIGARMDDFAMEFLNMADRSFGE

Sequences:

>Translated_237_residues
MLDLRLGDALLFETPVAFLLQTDLWDMVQHTGPAGKVVLVVLVFFSVSSWTFIFSKLSALRGARQSNARFLRAFRKSSGM
EAVMVASEQFRPSPLVAVFDFGYEELERQVKSRGSIVNRTALERTLQLGVNEEISKLERNMSWLATTASVTPFIGLLGTV
LGIIRAFEDLSQMGSTSIKAIGPGIAEALITTAVGLFAAIPAAVFYNYFGHVTREIGARMDDFAMEFLNMADRSFGE
>Mature_237_residues
MLDLRLGDALLFETPVAFLLQTDLWDMVQHTGPAGKVVLVVLVFFSVSSWTFIFSKLSALRGARQSNARFLRAFRKSSGM
EAVMVASEQFRPSPLVAVFDFGYEELERQVKSRGSIVNRTALERTLQLGVNEEISKLERNMSWLATTASVTPFIGLLGTV
LGIIRAFEDLSQMGSTSIKAIGPGIAEALITTAVGLFAAIPAAVFYNYFGHVTREIGARMDDFAMEFLNMADRSFGE

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=210, Percent_Identity=31.4285714285714, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789381, Length=234, Percent_Identity=34.1880341880342, Blast_Score=107, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26090; Mature: 26090

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLRLGDALLFETPVAFLLQTDLWDMVQHTGPAGKVVLVVLVFFSVSSWTFIFSKLSAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGARQSNARFLRAFRKSSGMEAVMVASEQFRPSPLVAVFDFGYEELERQVKSRGSIVNRT
HCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCHHHHH
ALERTLQLGVNEEISKLERNMSWLATTASVTPFIGLLGTVLGIIRAFEDLSQMGSTSIKA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IGPGIAEALITTAVGLFAAIPAAVFYNYFGHVTREIGARMDDFAMEFLNMADRSFGE
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDLRLGDALLFETPVAFLLQTDLWDMVQHTGPAGKVVLVVLVFFSVSSWTFIFSKLSAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGARQSNARFLRAFRKSSGMEAVMVASEQFRPSPLVAVFDFGYEELERQVKSRGSIVNRT
HCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCHHHHH
ALERTLQLGVNEEISKLERNMSWLATTASVTPFIGLLGTVLGIIRAFEDLSQMGSTSIKA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IGPGIAEALITTAVGLFAAIPAAVFYNYFGHVTREIGARMDDFAMEFLNMADRSFGE
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]