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The map label for this gene is ctaC [H]

Identifier: 116619636

GI number: 116619636

Start: 608312

End: 609310

Strand: Direct

Name: ctaC [H]

Synonym: Acid_0497

Alternate gene names: 116619636

Gene position: 608312-609310 (Clockwise)

Preceding gene: 116619635

Following gene: 116619637

Centisome position: 6.1

GC content: 59.46

Gene sequence:

>999_bases
ATGGGTAAATTTCAATTGTTTCCGGTACAGGCCTCCACGCTCGCGCCCGAGGTGGATCACCTCCTGTACTTTCTGCTCGC
TGTCAGCACCTTCTTCACGCTGCTGATCTTCGGCGCGATTTTCTATTTCGCGATTCGCTATCGCCGGCGTTCGGAGAACG
AACTGCCGCACGTGGCCCACACCGGCTACACGTTGGAAATCGTCTGGAGCGTGATTCCGTTCGGCCTCACTATGGTGATG
TTCACCTGGGGCGCCAGCATCTTTTTCAACTCCCGCAAACCGCCAAACGACGCCATTCAGATCTACGCCGTGGGCAAGCA
GTGGATGTGGAAGCTGGAGCACATGGAAGGGCAGCGCGAAATCAACGAGCTGCACATTCCCGTGGGCCGCCCCGTCCGTA
TCACGATGGCCAGTGAAGACGTGATCCACAGTTTCTTCATCCCCGCGTTCCGCACCAAGCAGGACGTGGTTCCCGGCACT
TACACCACCACCTGGTTCACGGCCACGAAGACCGGGAAATATCACCTGTTCTGCGCCGAGTACTGCGGCACCCGCCACTC
CGGCATGATCGGCTGGATCTATGTGATGGAGCCTGCCGACTACGAGGCCTGGCTCGGTGGAGGCTCAGGCTCGGGTTCGC
TCGCCGATAACGGTAAGAAGCTTTTCGAACAACTCGCCTGCAACAACTGCCATCGCGAGGACAACACCGGCCGCTGCCCC
AACCTGGTGGGCCTCTTCGGCCAACCGGTGAAACTCTCCGGCGGCAATTCGGTAAAGGCCGACGAGGCCTACATCCGCGA
ATCCATCCTGCAGCCGCAGGCCAAGATTGTGGCCGGCTACGAGCCGGTGATGCCCACCTTTCAGGGACTGGTTACCGAAG
ACCAGATTCTGCAGTTGGTGGAATATGTGAAATCCATCGGTCCCAAACCGGCCGCAGGTCCGGTGAATAGCGGGACCACT
CCAGCCGCGGGGACTGTGACCACTCCGGCAAAACGTTGA

Upstream 100 bases:

>100_bases
CACGCTGGTCTGCGGCGTGTTCCTCTTCATCTTCCTGCGCCGTGATGTTCGCAGTGACCGGCGCGCTCTTGAATACAACA
GGCGGGTTGGATAGCACACG

Downstream 100 bases:

>100_bases
GAACCATATGATTACCGAAGCCGCTGTAGAACGCGAGCATTACCTGAACGCCAGTTACGGCCTGAAGTCCTGGCTGCTGA
CCAAGGACCACAAGCGCATC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MGKFQLFPVQASTLAPEVDHLLYFLLAVSTFFTLLIFGAIFYFAIRYRRRSENELPHVAHTGYTLEIVWSVIPFGLTMVM
FTWGASIFFNSRKPPNDAIQIYAVGKQWMWKLEHMEGQREINELHIPVGRPVRITMASEDVIHSFFIPAFRTKQDVVPGT
YTTTWFTATKTGKYHLFCAEYCGTRHSGMIGWIYVMEPADYEAWLGGGSGSGSLADNGKKLFEQLACNNCHREDNTGRCP
NLVGLFGQPVKLSGGNSVKADEAYIRESILQPQAKIVAGYEPVMPTFQGLVTEDQILQLVEYVKSIGPKPAAGPVNSGTT
PAAGTVTTPAKR

Sequences:

>Translated_332_residues
MGKFQLFPVQASTLAPEVDHLLYFLLAVSTFFTLLIFGAIFYFAIRYRRRSENELPHVAHTGYTLEIVWSVIPFGLTMVM
FTWGASIFFNSRKPPNDAIQIYAVGKQWMWKLEHMEGQREINELHIPVGRPVRITMASEDVIHSFFIPAFRTKQDVVPGT
YTTTWFTATKTGKYHLFCAEYCGTRHSGMIGWIYVMEPADYEAWLGGGSGSGSLADNGKKLFEQLACNNCHREDNTGRCP
NLVGLFGQPVKLSGGNSVKADEAYIRESILQPQAKIVAGYEPVMPTFQGLVTEDQILQLVEYVKSIGPKPAAGPVNSGTT
PAAGTVTTPAKR
>Mature_331_residues
GKFQLFPVQASTLAPEVDHLLYFLLAVSTFFTLLIFGAIFYFAIRYRRRSENELPHVAHTGYTLEIVWSVIPFGLTMVMF
TWGASIFFNSRKPPNDAIQIYAVGKQWMWKLEHMEGQREINELHIPVGRPVRITMASEDVIHSFFIPAFRTKQDVVPGTY
TTTWFTATKTGKYHLFCAEYCGTRHSGMIGWIYVMEPADYEAWLGGGSGSGSLADNGKKLFEQLACNNCHREDNTGRCPN
LVGLFGQPVKLSGGNSVKADEAYIRESILQPQAKIVAGYEPVMPTFQGLVTEDQILQLVEYVKSIGPKPAAGPVNSGTTP
AAGTVTTPAKR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=147, Percent_Identity=27.2108843537415, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786635, Length=194, Percent_Identity=27.319587628866, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6226540, Length=198, Percent_Identity=21.7171717171717, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36915; Mature: 36784

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFQLFPVQASTLAPEVDHLLYFLLAVSTFFTLLIFGAIFYFAIRYRRRSENELPHVAH
CCCEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGYTLEIVWSVIPFGLTMVMFTWGASIFFNSRKPPNDAIQIYAVGKQWMWKLEHMEGQRE
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECHHHHHHHHHHCCHHH
INELHIPVGRPVRITMASEDVIHSFFIPAFRTKQDVVPGTYTTTWFTATKTGKYHLFCAE
HHHEECCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEHH
YCGTRHSGMIGWIYVMEPADYEAWLGGGSGSGSLADNGKKLFEQLACNNCHREDNTGRCP
HCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
NLVGLFGQPVKLSGGNSVKADEAYIRESILQPQAKIVAGYEPVMPTFQGLVTEDQILQLV
CHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCHHEEECCCCHHHHHHHCCCHHHHHHHH
EYVKSIGPKPAAGPVNSGTTPAAGTVTTPAKR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GKFQLFPVQASTLAPEVDHLLYFLLAVSTFFTLLIFGAIFYFAIRYRRRSENELPHVAH
CCEEEEEECHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
TGYTLEIVWSVIPFGLTMVMFTWGASIFFNSRKPPNDAIQIYAVGKQWMWKLEHMEGQRE
CCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEECHHHHHHHHHHCCHHH
INELHIPVGRPVRITMASEDVIHSFFIPAFRTKQDVVPGTYTTTWFTATKTGKYHLFCAE
HHHEECCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEHH
YCGTRHSGMIGWIYVMEPADYEAWLGGGSGSGSLADNGKKLFEQLACNNCHREDNTGRCP
HCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
NLVGLFGQPVKLSGGNSVKADEAYIRESILQPQAKIVAGYEPVMPTFQGLVTEDQILQLV
CHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCHHEEECCCCHHHHHHHCCCHHHHHHHH
EYVKSIGPKPAAGPVNSGTTPAAGTVTTPAKR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]