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The map label for this gene is yclF [H]

Identifier: 116619513

GI number: 116619513

Start: 472549

End: 474060

Strand: Direct

Name: yclF [H]

Synonym: Acid_0372

Alternate gene names: 116619513

Gene position: 472549-474060 (Clockwise)

Preceding gene: 116619512

Following gene: 116619514

Centisome position: 4.74

GC content: 62.7

Gene sequence:

>1512_bases
ATGGCATCGCGCTCTGAACACGATCAGCAGTCCCTGGAAGCCGCTCGCGCGGATACGAGTTTTTTCGGTCATCCGCGAGG
GTTGGCGACGCTATTCTTCACGGAGATGTGGGAGCGCTTCAGCTACTACGGCATGCGCGCGATCCTCATCTTCTACCTGA
CCGCGACCATCGCCAAGGGCGGACTGGGGTTTGCCGATTCGAAGGCGGGCGCGGTTTACGGGCTCTACACGGCGATGGTG
TACCTGATGTGCCTGGGGGGTGGATGGGTCGCCGACCGGATCACGGGCGCGCGGCGCGCGGTGTTGATCGGCGGGATTCT
GATCGCCTGCGGGGAATTCTGCCTCGTGGTGCCCTCGGAGGTGGCGTTCTATAGCGGACTGGTGCTGCTGATTGCGGGCA
CGGGGATGTTGAAGGGCAACGTCAGCATCATCGTGGGGCAACTCTATGCGCCGGGCGATTCGCGGCGCGATTCGGGATTT
TCGATTTTCTACATGGGCATCAATATCGGCGCGCTGATTTCGCCGCTCATCTGCGGCTATGTGGGCGAGTGGATCAGCTG
GCGGCTGGGCTTTGCGGTCGCCGGTATCGGCATGCTGCTGGGGTTGATTCAGTTCCTGGTGACGAGCCGCCACCTGGGTT
CGGCGGGACTACATCCGGCTTCAACAGGCGACCCGGAGGAAGACCGGAAGTCGAAGAAGAACGCGATTCTCACGGTCGGC
GGCGGGCTGGCTGTGCTGGCGATGCTGGGTGGGTTGGCCGCGGCCGGCGTAGTGCAAGTGAACGCCAACATGCTCTCCGA
CGCGTTGGGCTGGTGCCTGATCGGGATCTCGGCGCTGGTGTTTGCGTGGCTGATTTTCTTTGGCAACTGGACGCCGGTGG
AGCGCAAGCGCAGCGCGGCAATTCTTGTGCTGTTCGTTTCGTCGGCACTGTTCTGGGCCGCATTTGAACAGGCGGGCTCG
TCGCTGAGCCTGTTCGCGGAACGCGGAACAGATTGCCGTATTTTCGGGATCGCGTTTCCGGCGAGCTGGTTCCAATCCGT
GCAGCCGGTTTTCGTGATTGCGCTGGCGCCGGTCTTTGGATGGTTGTGGCTGGCGCTGCGCAAGCGGGAGCCATCGAGCC
CCGCGAAGTTCTCGCTCGGCCTGACGTTCGGCGGCCTGGCGTTTGCGATTCTGGTGCCGGCGGCGTATCTGGTGGTCGGC
GGGCAGAAGGTAGCTCCGTGGTGGTTGATCGCGACTTACTTCCTGCAGACGCTGGGCGAGCTATGCTTGAGCCCGGTGGG
TTTGAGCGCGATGACGAAGCTGGCCCCAGCGCGGGTGGCGGGATTCATTATGGGAATGTGGTTCCTCTCGACGAGCATCG
GGAACTGGCTGGCGGGGAAGGCGGCGTCATTGTATAGCTCGATGCCGCTGCCGACGTTGTTCGGATCGGTGGCAATTTTC
AGTCTCGGAGCGGCGGTGGTGCTGGCGCTCTTGATTAAGCCGACGGTGCGGTTGATGCAGGGAGTGAAGTAG

Upstream 100 bases:

>100_bases
CAATCGGGCCACGAATGCACACGCATTCGCGGCCCTTTTTGTTTGTGGATTTGCCTCGGTACCCATCATGCATATACACT
GGCGATGCCGGTAAACACCT

Downstream 100 bases:

>100_bases
GTCGGGGGGTCTACCGGCACCGTGTTATCCTGCTCGCATGCAGGTAAGTTTGACTCCACACGGTGAAGAACTTCTGCGGC
AGCAACTCGCCCGAGGTTTG

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MASRSEHDQQSLEAARADTSFFGHPRGLATLFFTEMWERFSYYGMRAILIFYLTATIAKGGLGFADSKAGAVYGLYTAMV
YLMCLGGGWVADRITGARRAVLIGGILIACGEFCLVVPSEVAFYSGLVLLIAGTGMLKGNVSIIVGQLYAPGDSRRDSGF
SIFYMGINIGALISPLICGYVGEWISWRLGFAVAGIGMLLGLIQFLVTSRHLGSAGLHPASTGDPEEDRKSKKNAILTVG
GGLAVLAMLGGLAAAGVVQVNANMLSDALGWCLIGISALVFAWLIFFGNWTPVERKRSAAILVLFVSSALFWAAFEQAGS
SLSLFAERGTDCRIFGIAFPASWFQSVQPVFVIALAPVFGWLWLALRKREPSSPAKFSLGLTFGGLAFAILVPAAYLVVG
GQKVAPWWLIATYFLQTLGELCLSPVGLSAMTKLAPARVAGFIMGMWFLSTSIGNWLAGKAASLYSSMPLPTLFGSVAIF
SLGAAVVLALLIKPTVRLMQGVK

Sequences:

>Translated_503_residues
MASRSEHDQQSLEAARADTSFFGHPRGLATLFFTEMWERFSYYGMRAILIFYLTATIAKGGLGFADSKAGAVYGLYTAMV
YLMCLGGGWVADRITGARRAVLIGGILIACGEFCLVVPSEVAFYSGLVLLIAGTGMLKGNVSIIVGQLYAPGDSRRDSGF
SIFYMGINIGALISPLICGYVGEWISWRLGFAVAGIGMLLGLIQFLVTSRHLGSAGLHPASTGDPEEDRKSKKNAILTVG
GGLAVLAMLGGLAAAGVVQVNANMLSDALGWCLIGISALVFAWLIFFGNWTPVERKRSAAILVLFVSSALFWAAFEQAGS
SLSLFAERGTDCRIFGIAFPASWFQSVQPVFVIALAPVFGWLWLALRKREPSSPAKFSLGLTFGGLAFAILVPAAYLVVG
GQKVAPWWLIATYFLQTLGELCLSPVGLSAMTKLAPARVAGFIMGMWFLSTSIGNWLAGKAASLYSSMPLPTLFGSVAIF
SLGAAVVLALLIKPTVRLMQGVK
>Mature_502_residues
ASRSEHDQQSLEAARADTSFFGHPRGLATLFFTEMWERFSYYGMRAILIFYLTATIAKGGLGFADSKAGAVYGLYTAMVY
LMCLGGGWVADRITGARRAVLIGGILIACGEFCLVVPSEVAFYSGLVLLIAGTGMLKGNVSIIVGQLYAPGDSRRDSGFS
IFYMGINIGALISPLICGYVGEWISWRLGFAVAGIGMLLGLIQFLVTSRHLGSAGLHPASTGDPEEDRKSKKNAILTVGG
GLAVLAMLGGLAAAGVVQVNANMLSDALGWCLIGISALVFAWLIFFGNWTPVERKRSAAILVLFVSSALFWAAFEQAGSS
LSLFAERGTDCRIFGIAFPASWFQSVQPVFVIALAPVFGWLWLALRKREPSSPAKFSLGLTFGGLAFAILVPAAYLVVGG
QKVAPWWLIATYFLQTLGELCLSPVGLSAMTKLAPARVAGFIMGMWFLSTSIGNWLAGKAASLYSSMPLPTLFGSVAIFS
LGAAVVLALLIKPTVRLMQGVK

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=421, Percent_Identity=25.41567695962, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI226371746, Length=206, Percent_Identity=29.126213592233, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790572, Length=451, Percent_Identity=32.1507760532151, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787922, Length=512, Percent_Identity=27.734375, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786927, Length=464, Percent_Identity=32.9741379310345, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1789911, Length=490, Percent_Identity=27.1428571428571, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71987453, Length=386, Percent_Identity=30.0518134715026, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=198, Percent_Identity=31.3131313131313, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639583, Length=372, Percent_Identity=27.4193548387097, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639581, Length=361, Percent_Identity=27.7008310249307, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24639585, Length=361, Percent_Identity=27.7008310249307, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28571098, Length=409, Percent_Identity=24.2053789731051, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571102, Length=409, Percent_Identity=24.2053789731051, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571100, Length=409, Percent_Identity=24.2053789731051, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53463; Mature: 53331

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRSEHDQQSLEAARADTSFFGHPRGLATLFFTEMWERFSYYGMRAILIFYLTATIAKG
CCCCCCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLGFADSKAGAVYGLYTAMVYLMCLGGGWVADRITGARRAVLIGGILIACGEFCLVVPSE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHEECCHH
VAFYSGLVLLIAGTGMLKGNVSIIVGQLYAPGDSRRDSGFSIFYMGINIGALISPLICGY
HHHHHCHHEEEECCCEEECCCEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
VGEWISWRLGFAVAGIGMLLGLIQFLVTSRHLGSAGLHPASTGDPEEDRKSKKNAILTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEC
GGLAVLAMLGGLAAAGVVQVNANMLSDALGWCLIGISALVFAWLIFFGNWTPVERKRSAA
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ILVLFVSSALFWAAFEQAGSSLSLFAERGTDCRIFGIAFPASWFQSVQPVFVIALAPVFG
HHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHH
WLWLALRKREPSSPAKFSLGLTFGGLAFAILVPAAYLVVGGQKVAPWWLIATYFLQTLGE
HHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LCLSPVGLSAMTKLAPARVAGFIMGMWFLSTSIGNWLAGKAASLYSSMPLPTLFGSVAIF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SLGAAVVLALLIKPTVRLMQGVK
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASRSEHDQQSLEAARADTSFFGHPRGLATLFFTEMWERFSYYGMRAILIFYLTATIAKG
CCCCCHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLGFADSKAGAVYGLYTAMVYLMCLGGGWVADRITGARRAVLIGGILIACGEFCLVVPSE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHEECCHH
VAFYSGLVLLIAGTGMLKGNVSIIVGQLYAPGDSRRDSGFSIFYMGINIGALISPLICGY
HHHHHCHHEEEECCCEEECCCEEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHH
VGEWISWRLGFAVAGIGMLLGLIQFLVTSRHLGSAGLHPASTGDPEEDRKSKKNAILTVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCEEEEEC
GGLAVLAMLGGLAAAGVVQVNANMLSDALGWCLIGISALVFAWLIFFGNWTPVERKRSAA
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ILVLFVSSALFWAAFEQAGSSLSLFAERGTDCRIFGIAFPASWFQSVQPVFVIALAPVFG
HHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHH
WLWLALRKREPSSPAKFSLGLTFGGLAFAILVPAAYLVVGGQKVAPWWLIATYFLQTLGE
HHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LCLSPVGLSAMTKLAPARVAGFIMGMWFLSTSIGNWLAGKAASLYSSMPLPTLFGSVAIF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SLGAAVVLALLIKPTVRLMQGVK
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]