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The map label for this gene is yjjA [H]

Identifier: 116619331

GI number: 116619331

Start: 241273

End: 242112

Strand: Direct

Name: yjjA [H]

Synonym: Acid_0188

Alternate gene names: 116619331

Gene position: 241273-242112 (Clockwise)

Preceding gene: 116619330

Following gene: 116619338

Centisome position: 2.42

GC content: 63.1

Gene sequence:

>840_bases
ATGTCATTCGCGGATCTTCGTGTCCTCAGTCTCGAGAGCCGGCGCGCCAGGGAGATGGAGACCCTCATCCTTCGCGAGGG
TGGCATCCCGTTTGTCGCGCCCTCCGTCAAGGAACGCGCGGTCGACGATGATTCCGCTGCCATCCATTTCGTCGAACAGC
TCGAAGCAGGCGAGTTCGAAATGCTCATCTGCATGACCTCCGTGGGCCTCACCCTGCTCCGCGATACCGTAACGAAGCAG
ATGCCGTCGGAGCGCCTCTCGGCCGCCCTCCGCCGCGTCACCATCGTCTCTCGCGGACCCAAGCCCGTCGGTGTCTTAAA
GGCGCTCGAAGTCCCCATTCACCTAGTGATCCCCGAACCCAATACCTGGAAAGAGATCGTGGAGGCGGTCGCTTCCCGCC
ACGAGCGGCGCATCGCCGTACAAGAGTACGGCAGGCCGAATCTCGAGATGAACCAGGCGCTTGAACGGTTAGGCTGCCGC
GTGACGCCCGTCGCCCTCTATCGGTGGGAACTGCCCGATGACGTACGCCCGCTCCGCGAAGCAGCCGCTCGCCTGGCCGC
ACGCGAATTTGATGTCGTCCTGTTCACATCATCCATCCAGCTCGACCACTTGCTCCAAATCGCGCGCACGCTTGGTCTCG
AGCAGGAGGTCTGCCGTGCCATGAGGCATGACGTGGTCGTCGCCTCGATCGGCGCGGTAATGACGTCCGCCTTGATCGCT
CACGGCCGCCCACCGGACGTGATTCCCAAACATCCGAAAATGTGGTCGCTCGTAAAAGCGGCGTCGGACGAAGCCGCTGC
CGTCCTCGCCGCGAAACGTGCCAACGAGCGGCGACCCTAA

Upstream 100 bases:

>100_bases
GGCTGGCGATTTTCTCAAGCAGAATTCGAAGGGATCGGGACAGACCTTCCCGTACCTCTTCGCGCAATACTCGTATTAGG
TACCGCAAAGCCCTTCTCAT

Downstream 100 bases:

>100_bases
CGTAAGGGAGCGCTACCCGCCCGTCCTCAATTCGTCAGCCCCACTCCGTATCTCCGCAAAATGCGCGCCAGCCGCACCGG
CTCATCCGTCAGGCACTCAT

Product: uroporphyrinogen III synthase HEM4

Products: coproporphyrinogen; CO2

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSFADLRVLSLESRRAREMETLILREGGIPFVAPSVKERAVDDDSAAIHFVEQLEAGEFEMLICMTSVGLTLLRDTVTKQ
MPSERLSAALRRVTIVSRGPKPVGVLKALEVPIHLVIPEPNTWKEIVEAVASRHERRIAVQEYGRPNLEMNQALERLGCR
VTPVALYRWELPDDVRPLREAAARLAAREFDVVLFTSSIQLDHLLQIARTLGLEQEVCRAMRHDVVVASIGAVMTSALIA
HGRPPDVIPKHPKMWSLVKAASDEAAAVLAAKRANERRP

Sequences:

>Translated_279_residues
MSFADLRVLSLESRRAREMETLILREGGIPFVAPSVKERAVDDDSAAIHFVEQLEAGEFEMLICMTSVGLTLLRDTVTKQ
MPSERLSAALRRVTIVSRGPKPVGVLKALEVPIHLVIPEPNTWKEIVEAVASRHERRIAVQEYGRPNLEMNQALERLGCR
VTPVALYRWELPDDVRPLREAAARLAAREFDVVLFTSSIQLDHLLQIARTLGLEQEVCRAMRHDVVVASIGAVMTSALIA
HGRPPDVIPKHPKMWSLVKAASDEAAAVLAAKRANERRP
>Mature_278_residues
SFADLRVLSLESRRAREMETLILREGGIPFVAPSVKERAVDDDSAAIHFVEQLEAGEFEMLICMTSVGLTLLRDTVTKQM
PSERLSAALRRVTIVSRGPKPVGVLKALEVPIHLVIPEPNTWKEIVEAVASRHERRIAVQEYGRPNLEMNQALERLGCRV
TPVALYRWELPDDVRPLREAAARLAAREFDVVLFTSSIQLDHLLQIARTLGLEQEVCRAMRHDVVVASIGAVMTSALIAH
GRPPDVIPKHPKMWSLVKAASDEAAAVLAAKRANERRP

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003754 [H]

Pfam domain/function: PF02602 HEM4 [H]

EC number: 4.1.1.37; 4.2.1.75

Molecular weight: Translated: 31050; Mature: 30918

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFADLRVLSLESRRAREMETLILREGGIPFVAPSVKERAVDDDSAAIHFVEQLEAGEFE
CCCCHHHEEHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCHHHHHHHHHHCCCCEE
MLICMTSVGLTLLRDTVTKQMPSERLSAALRRVTIVSRGPKPVGVLKALEVPIHLVIPEP
EEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCC
NTWKEIVEAVASRHERRIAVQEYGRPNLEMNQALERLGCRVTPVALYRWELPDDVRPLRE
CCHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
AAARLAAREFDVVLFTSSIQLDHLLQIARTLGLEQEVCRAMRHDVVVASIGAVMTSALIA
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRPPDVIPKHPKMWSLVKAASDEAAAVLAAKRANERRP
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFADLRVLSLESRRAREMETLILREGGIPFVAPSVKERAVDDDSAAIHFVEQLEAGEFE
CCCHHHEEHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCHHHHHHHHHHCCCCEE
MLICMTSVGLTLLRDTVTKQMPSERLSAALRRVTIVSRGPKPVGVLKALEVPIHLVIPEP
EEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEECCC
NTWKEIVEAVASRHERRIAVQEYGRPNLEMNQALERLGCRVTPVALYRWELPDDVRPLRE
CCHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
AAARLAAREFDVVLFTSSIQLDHLLQIARTLGLEQEVCRAMRHDVVVASIGAVMTSALIA
HHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRPPDVIPKHPKMWSLVKAASDEAAAVLAAKRANERRP
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uroporphyrinogen III

Specific reaction: uroporphyrinogen III = coproporphyrinogen + 4 CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]