Click here to switch to the map view.

The map label for this gene is zraS [C]

Identifier: 116619301

GI number: 116619301

Start: 199257

End: 201608

Strand: Direct

Name: zraS [C]

Synonym: Acid_0157

Alternate gene names: 116619301

Gene position: 199257-201608 (Clockwise)

Preceding gene: 116619298

Following gene: 116619303

Centisome position: 2.0

GC content: 60.03

Gene sequence:

>2352_bases
GTGTTCCAAACAAATCCACTGGCTACGCCGTGGGTAGTGCTGCGCCTTCGATATTGGTGGCCGGCCCTATACCTGGGTTT
AGCTGCCATCGAGGTCGCGGCGCAGGGCACTGCCGCGCTGTCGATCGGCGAAGCGATTCGCAACGAGAGCGATCACCATG
CGGTTCACGGCGGAGAAGCGGTCGTGCTGCGCGGCGTGGTCACCGATACCGCACACGATGTGGGGATGGGCAATAGTCTG
TCGAACCTACAGGACGCCACGGGCGGAATCGCGTTATTTGGAGACCACAAGGTGCTTCCGCCGGCGAGTTTGAAGCGCGG
CGATGTGGTGGAAGCGCGCGGCAAGTTGATGCAGTACCGGGGAATGGAAGAGCTGCAGCTGGAATCGGTTCGTCGCACCG
GCAGCGCCCCGGTTCCTCCCGCGGTGGAGGTTTCGGCTGCCAATCTGCACAACGAGGACCACTCCGGCAGACTTGTGCGG
GTCAAGGGACGGATCATCCTCCTGCCCAACGGCTGGATCGCGCTGCGCGACAATTCCGGAGAAATACCTGTCTACCTGCT
TCGGTCCTTCTTTCAGAGCACCAGCTTCATGAACCGGCTGCTGGAAGGCGGCCAGGTCGAAATTGTGGGTTTTGCGCGGC
AACGCGTCGGTGATGGTGAGAGTGCGGGGTCGGGATACCTTCTGTCGCCGCGAGACGACCAGGATTTCAAATTCGCTCCG
CAGACGCGCTACCGGGAGACGGCCGCGGTGACGTTCGTAGCATTGGGCTGTTTCCTGTATCTTTGGCAGCGCCGCCGGGC
AGCCGAAAAAAGGGAGCGGGCGCTCGCTGTGCTTTCGGAAGGGTGGAAGGAGAGCGACGAACGATTTCGCCAGATGGCCG
CCAACGTCGGCGAGGTCTTCTGGATGCTCGAGGTTGAGAAGAACGAGCTGCTTTACGTGAGCCCGGCCTTCGGCAGGATC
TGGGGGCGCGACTCCGGGATGCTGGAACCGCGAGAAAACCTGCTCGATACGGTACATCCCGAGGATCGCGATCGTGTCCG
GTCGTTTCTAGAGAGAAACGTCCGGCAGGCCCTTGAAGAGACCTATCGAATCGTCCGCCCAAATGGTGCGGTGCGTTGGA
TTCACGACCGTTCTTTTCCTATATTCAACCAGGAGGGCAAGCCATACCGGGTAGCGGGAATTGCGGCCGATATTACCGAC
AGACGGGAACTGGAAGAGGAGCTCCGCCAAGCGCAGAAGATGGACGCCGTCGGCAGGCTGGCTGGAGGCGTTGCCCATGA
TTTCAATAATCTGCTGACCGTCATTGTCGGATACTCACGAACCTTGCTGGACCGCTCGCCGTCGGACGACTCGACGCGCT
TTCAGTTGGAGCAGATACTTCAGGCCTCCAACCGTGCTGCCGCGTTGACCAGCCAGCTGCTGGCGTTCAGCCGGAAGCAG
GTGCCGCAGCCGCGGCTGATCAACCTGAACCACCTGGTAATGAACGTAGAGTCCCTGTTGCGGCGCGTGATGGGAGAGCA
CATAGTTTTTCATGCCGTGCTCGCCGATTGCCTGCTGTATGTAAAGGCCGATCCGAATCAACTGGAGCAGATACTAATCA
ATCTCGCGGCAAATGCGCGCGACGCGATGCCCGACGGAGGCGAGTTCCGGATCGAAACGGCACTCGTGGATGCGCGGGAG
GAAGCCGCAGAAGACCGCGCGGAAGAGAAATGCGTCCTGCTGCGGGTAAGGGATTCCGGGATCGGCATGAACGAGGCGGT
TCTCGAGCATGCCTTCGAGCCCTTCTTCACGACCAAGGGAGTGGGCAAGGGAACGGGTCTCGGACTGAGCACCGTGTACG
GCCTGGTTCAGCAGAACCATGGCACCATTCATGTAAGCAGCGAACGAGGACACGGCACGGTTTTCGAGATCTACCTTCCA
GCCGTTTCAGGGGGAGAGCAGGCAGAAGAAACCAGGGCGGTGAACGGGACCCAGCACGGACATGAAACCATCCTGGTTGC
CGAAGACGAGGCCGGGGTCCGCAAGCTGGTGTGTGATGCCTTGGAGCTGTTTGGCTATACCGTGCTGGCGGCAGCGGATG
GTTATGAAGCGATGCGCATCCTCGAACAGTGCAATGGACCCGTGCACCTGTTGCTGACCGATGTCATCATGCCGTTGATG
GGCGGGCGGGAACTCGCGAAACGCGTGCAATCCTCTAAGCCGGAGACGAAGGTGATCTACATGTCCGGCTATACGGACGA
TACCCTGGCGTTTCACGGATTCCCGCAATCCAACGATGGCTTCATACAGAAGCCATTCACTATGACCGTGCTGGCGGAGA
AGGTCCGGCAAGTGTTGTCAAACGGATCCTAG

Upstream 100 bases:

>100_bases
AATCCCTTGCGGTCGGGGGCATCGATGAGAAGGACGGCCGTGCCGGGCATGGTTCAGGATAACCCGGTGATTCAGCAGCA
TTTGCTAAAATCGTCGGACA

Downstream 100 bases:

>100_bases
CGCTACCGGTGGCCTCCGCCGTGTCCTCCGCCGCCACCGAAGCCGTGTCCTCCGCCGCCGCCGAAGCCGTGTCCTCCGCC
GCCGAACCCGCCGCCGAAAC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MFQTNPLATPWVVLRLRYWWPALYLGLAAIEVAAQGTAALSIGEAIRNESDHHAVHGGEAVVLRGVVTDTAHDVGMGNSL
SNLQDATGGIALFGDHKVLPPASLKRGDVVEARGKLMQYRGMEELQLESVRRTGSAPVPPAVEVSAANLHNEDHSGRLVR
VKGRIILLPNGWIALRDNSGEIPVYLLRSFFQSTSFMNRLLEGGQVEIVGFARQRVGDGESAGSGYLLSPRDDQDFKFAP
QTRYRETAAVTFVALGCFLYLWQRRRAAEKRERALAVLSEGWKESDERFRQMAANVGEVFWMLEVEKNELLYVSPAFGRI
WGRDSGMLEPRENLLDTVHPEDRDRVRSFLERNVRQALEETYRIVRPNGAVRWIHDRSFPIFNQEGKPYRVAGIAADITD
RRELEEELRQAQKMDAVGRLAGGVAHDFNNLLTVIVGYSRTLLDRSPSDDSTRFQLEQILQASNRAAALTSQLLAFSRKQ
VPQPRLINLNHLVMNVESLLRRVMGEHIVFHAVLADCLLYVKADPNQLEQILINLAANARDAMPDGGEFRIETALVDARE
EAAEDRAEEKCVLLRVRDSGIGMNEAVLEHAFEPFFTTKGVGKGTGLGLSTVYGLVQQNHGTIHVSSERGHGTVFEIYLP
AVSGGEQAEETRAVNGTQHGHETILVAEDEAGVRKLVCDALELFGYTVLAAADGYEAMRILEQCNGPVHLLLTDVIMPLM
GGRELAKRVQSSKPETKVIYMSGYTDDTLAFHGFPQSNDGFIQKPFTMTVLAEKVRQVLSNGS

Sequences:

>Translated_783_residues
MFQTNPLATPWVVLRLRYWWPALYLGLAAIEVAAQGTAALSIGEAIRNESDHHAVHGGEAVVLRGVVTDTAHDVGMGNSL
SNLQDATGGIALFGDHKVLPPASLKRGDVVEARGKLMQYRGMEELQLESVRRTGSAPVPPAVEVSAANLHNEDHSGRLVR
VKGRIILLPNGWIALRDNSGEIPVYLLRSFFQSTSFMNRLLEGGQVEIVGFARQRVGDGESAGSGYLLSPRDDQDFKFAP
QTRYRETAAVTFVALGCFLYLWQRRRAAEKRERALAVLSEGWKESDERFRQMAANVGEVFWMLEVEKNELLYVSPAFGRI
WGRDSGMLEPRENLLDTVHPEDRDRVRSFLERNVRQALEETYRIVRPNGAVRWIHDRSFPIFNQEGKPYRVAGIAADITD
RRELEEELRQAQKMDAVGRLAGGVAHDFNNLLTVIVGYSRTLLDRSPSDDSTRFQLEQILQASNRAAALTSQLLAFSRKQ
VPQPRLINLNHLVMNVESLLRRVMGEHIVFHAVLADCLLYVKADPNQLEQILINLAANARDAMPDGGEFRIETALVDARE
EAAEDRAEEKCVLLRVRDSGIGMNEAVLEHAFEPFFTTKGVGKGTGLGLSTVYGLVQQNHGTIHVSSERGHGTVFEIYLP
AVSGGEQAEETRAVNGTQHGHETILVAEDEAGVRKLVCDALELFGYTVLAAADGYEAMRILEQCNGPVHLLLTDVIMPLM
GGRELAKRVQSSKPETKVIYMSGYTDDTLAFHGFPQSNDGFIQKPFTMTVLAEKVRQVLSNGS
>Mature_783_residues
MFQTNPLATPWVVLRLRYWWPALYLGLAAIEVAAQGTAALSIGEAIRNESDHHAVHGGEAVVLRGVVTDTAHDVGMGNSL
SNLQDATGGIALFGDHKVLPPASLKRGDVVEARGKLMQYRGMEELQLESVRRTGSAPVPPAVEVSAANLHNEDHSGRLVR
VKGRIILLPNGWIALRDNSGEIPVYLLRSFFQSTSFMNRLLEGGQVEIVGFARQRVGDGESAGSGYLLSPRDDQDFKFAP
QTRYRETAAVTFVALGCFLYLWQRRRAAEKRERALAVLSEGWKESDERFRQMAANVGEVFWMLEVEKNELLYVSPAFGRI
WGRDSGMLEPRENLLDTVHPEDRDRVRSFLERNVRQALEETYRIVRPNGAVRWIHDRSFPIFNQEGKPYRVAGIAADITD
RRELEEELRQAQKMDAVGRLAGGVAHDFNNLLTVIVGYSRTLLDRSPSDDSTRFQLEQILQASNRAAALTSQLLAFSRKQ
VPQPRLINLNHLVMNVESLLRRVMGEHIVFHAVLADCLLYVKADPNQLEQILINLAANARDAMPDGGEFRIETALVDARE
EAAEDRAEEKCVLLRVRDSGIGMNEAVLEHAFEPFFTTKGVGKGTGLGLSTVYGLVQQNHGTIHVSSERGHGTVFEIYLP
AVSGGEQAEETRAVNGTQHGHETILVAEDEAGVRKLVCDALELFGYTVLAAADGYEAMRILEQCNGPVHLLLTDVIMPLM
GGRELAKRVQSSKPETKVIYMSGYTDDTLAFHGFPQSNDGFIQKPFTMTVLAEKVRQVLSNGS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=245, Percent_Identity=32.6530612244898, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=30.8550185873606, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=30.1652892561983, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=24.0694789081886, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=27.4809160305344, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=287, Percent_Identity=25.7839721254355, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86853; Mature: 86853

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTNPLATPWVVLRLRYWWPALYLGLAAIEVAAQGTAALSIGEAIRNESDHHAVHGGEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCE
VVLRGVVTDTAHDVGMGNSLSNLQDATGGIALFGDHKVLPPASLKRGDVVEARGKLMQYR
EEEEEEHHCCCHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
GMEELQLESVRRTGSAPVPPAVEVSAANLHNEDHSGRLVRVKGRIILLPNGWIALRDNSG
CHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCCCEEEEECEEEEEECCEEEEECCCC
EIPVYLLRSFFQSTSFMNRLLEGGQVEIVGFARQRVGDGESAGSGYLLSPRDDQDFKFAP
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCEEECCCCCCCCCCCC
QTRYRETAAVTFVALGCFLYLWQRRRAAEKRERALAVLSEGWKESDERFRQMAANVGEVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHEE
WMLEVEKNELLYVSPAFGRIWGRDSGMLEPRENLLDTVHPEDRDRVRSFLERNVRQALEE
EEEEECCCCEEEEECHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TYRIVRPNGAVRWIHDRSFPIFNQEGKPYRVAGIAADITDRRELEEELRQAQKMDAVGRL
HHHEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGGVAHDFNNLLTVIVGYSRTLLDRSPSDDSTRFQLEQILQASNRAAALTSQLLAFSRKQ
HHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
VPQPRLINLNHLVMNVESLLRRVMGEHIVFHAVLADCLLYVKADPNQLEQILINLAANAR
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCC
DAMPDGGEFRIETALVDAREEAAEDRAEEKCVLLRVRDSGIGMNEAVLEHAFEPFFTTKG
CCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VGKGTGLGLSTVYGLVQQNHGTIHVSSERGHGTVFEIYLPAVSGGEQAEETRAVNGTQHG
CCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCC
HETILVAEDEAGVRKLVCDALELFGYTVLAAADGYEAMRILEQCNGPVHLLLTDVIMPLM
CEEEEEECCCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GGRELAKRVQSSKPETKVIYMSGYTDDTLAFHGFPQSNDGFIQKPFTMTVLAEKVRQVLS
CCHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCCCEECCHHHHHHHHHHHHHHC
NGS
CCC
>Mature Secondary Structure
MFQTNPLATPWVVLRLRYWWPALYLGLAAIEVAAQGTAALSIGEAIRNESDHHAVHGGEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCE
VVLRGVVTDTAHDVGMGNSLSNLQDATGGIALFGDHKVLPPASLKRGDVVEARGKLMQYR
EEEEEEHHCCCHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
GMEELQLESVRRTGSAPVPPAVEVSAANLHNEDHSGRLVRVKGRIILLPNGWIALRDNSG
CHHHHHHHHHHHCCCCCCCCCEEEEHHHCCCCCCCCCEEEEECEEEEEECCEEEEECCCC
EIPVYLLRSFFQSTSFMNRLLEGGQVEIVGFARQRVGDGESAGSGYLLSPRDDQDFKFAP
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCEEECCCCCCCCCCCC
QTRYRETAAVTFVALGCFLYLWQRRRAAEKRERALAVLSEGWKESDERFRQMAANVGEVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHEE
WMLEVEKNELLYVSPAFGRIWGRDSGMLEPRENLLDTVHPEDRDRVRSFLERNVRQALEE
EEEEECCCCEEEEECHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TYRIVRPNGAVRWIHDRSFPIFNQEGKPYRVAGIAADITDRRELEEELRQAQKMDAVGRL
HHHEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
AGGVAHDFNNLLTVIVGYSRTLLDRSPSDDSTRFQLEQILQASNRAAALTSQLLAFSRKQ
HHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
VPQPRLINLNHLVMNVESLLRRVMGEHIVFHAVLADCLLYVKADPNQLEQILINLAANAR
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCC
DAMPDGGEFRIETALVDAREEAAEDRAEEKCVLLRVRDSGIGMNEAVLEHAFEPFFTTKG
CCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCC
VGKGTGLGLSTVYGLVQQNHGTIHVSSERGHGTVFEIYLPAVSGGEQAEETRAVNGTQHG
CCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCC
HETILVAEDEAGVRKLVCDALELFGYTVLAAADGYEAMRILEQCNGPVHLLLTDVIMPLM
CEEEEEECCCCHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GGRELAKRVQSSKPETKVIYMSGYTDDTLAFHGFPQSNDGFIQKPFTMTVLAEKVRQVLS
CCHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCCCCEECCHHHHHHHHHHHHHHC
NGS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA