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The map label for this gene is kdpD [H]

Identifier: 116619221

GI number: 116619221

Start: 108011

End: 109051

Strand: Direct

Name: kdpD [H]

Synonym: Acid_0076

Alternate gene names: 116619221

Gene position: 108011-109051 (Clockwise)

Preceding gene: 116619220

Following gene: 116619222

Centisome position: 1.08

GC content: 66.57

Gene sequence:

>1041_bases
GTGAGGTCTGCCCCGCAAAGACGACTGGATCCGGACGAACTCCTTCGCCGTGTGCAGGCCGAGGAGCGGCGGGAGCGGCG
TGGACGCCTCAAGGTCTTTCTCGGATATGCGCCGCGGGTCGGCAAATCGCTGCGCATGTTCGACGAAGGCCGCCGCCGCA
AGGAGCGCGGGCAGGACGTTGTCGTGGCCGCCGTGCAAGAGAAGAGCACCGAGGCCGTCCGCGAAATCATCGTCCGCCTG
GAGCAGCTGCCAACGGTCGATGGCGCCATCGACCTGCCGGCCGTGTTTCGACGCCGCCCGTCCGTCTGTCTGGTCGATGA
ACTGGCCTTCGATAATCCCCCCGGCAGTGCCAATGCCTGCCGCTGGCAGGACGTGGACGCAATCCTCAATCAAGGCATCG
CGGTCATGTCCGCGATCAACGTGCAGCACATTCGCGAGCAGCAGCCGGCCGTCGAAGCGATCACGGGCAAACGTGCCACC
CGCTCCATTCCGCAGGAGTTCCTGCGCGAAGCCGACGAGATCGAGGTGGTGGACGCTCCGCCCGACCTCAGCATGGGCGA
CGCGCGCGCGCTCGCCGAACTCCGCGAGCTCGCGCTCCTTCTGGCCGCAGACGTGGTGGACCACCAGCTGCAGGCCTATC
TTGATTCGCACGGCGTCTCGGTCCACTGGGGCGCGCAGGAGCGCATCCTGGTCTGCCTCACTCCACGCAGCAACGCGCTC
GACATGCTGCACAGCGGCCAGCGCAACGCGCGCCGCTTCCACGGCGCTCTCCTGGTGGCCTACGTAGCGCAAGTCAACCT
CAGCCCGGCGGACCAGCAACGCCTCGACGACAACCTGGCGCTCGCCCGCGAGTTGGGCGCCGAAGTCCACTGTCTGCCTG
CTGGCGACTTTGTTGACTCGCTGCTCGCCTTCGCCCGCGAACACCGCATCACCCAATTGTTCCTCGGACACTCGCAGCGT
GAGCGCAGTCCCATTGAGCGGCTGATCGATGCGGCCGAGGACTTCGACATCCGGCTGTTCCCGCATGGAGAGGGCAAATG
A

Upstream 100 bases:

>100_bases
GTGAGGCGCGCGTTAACGTGCTTCAACTCAATCTCGCGCTGGATCAAGCCGCGCCGGGTCGGAGGTAGAGTATTAGCAGC
ATTACAGTCTTGCCAAACAA

Downstream 100 bases:

>100_bases
GCCGCCCCGGCCAGCTCAAGATCTACCTTGGCTATGCGGCCGGCGTCGGCAAAACCTACCGCATGCTCGAAGAGGCACAG
GCCCTGCGCGCCAAGGATAT

Product: osmosensitive K+ channel histidine kinase sensor subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MRSAPQRRLDPDELLRRVQAEERRERRGRLKVFLGYAPRVGKSLRMFDEGRRRKERGQDVVVAAVQEKSTEAVREIIVRL
EQLPTVDGAIDLPAVFRRRPSVCLVDELAFDNPPGSANACRWQDVDAILNQGIAVMSAINVQHIREQQPAVEAITGKRAT
RSIPQEFLREADEIEVVDAPPDLSMGDARALAELRELALLLAADVVDHQLQAYLDSHGVSVHWGAQERILVCLTPRSNAL
DMLHSGQRNARRFHGALLVAYVAQVNLSPADQQRLDDNLALARELGAEVHCLPAGDFVDSLLAFAREHRITQLFLGHSQR
ERSPIERLIDAAEDFDIRLFPHGEGK

Sequences:

>Translated_346_residues
MRSAPQRRLDPDELLRRVQAEERRERRGRLKVFLGYAPRVGKSLRMFDEGRRRKERGQDVVVAAVQEKSTEAVREIIVRL
EQLPTVDGAIDLPAVFRRRPSVCLVDELAFDNPPGSANACRWQDVDAILNQGIAVMSAINVQHIREQQPAVEAITGKRAT
RSIPQEFLREADEIEVVDAPPDLSMGDARALAELRELALLLAADVVDHQLQAYLDSHGVSVHWGAQERILVCLTPRSNAL
DMLHSGQRNARRFHGALLVAYVAQVNLSPADQQRLDDNLALARELGAEVHCLPAGDFVDSLLAFAREHRITQLFLGHSQR
ERSPIERLIDAAEDFDIRLFPHGEGK
>Mature_346_residues
MRSAPQRRLDPDELLRRVQAEERRERRGRLKVFLGYAPRVGKSLRMFDEGRRRKERGQDVVVAAVQEKSTEAVREIIVRL
EQLPTVDGAIDLPAVFRRRPSVCLVDELAFDNPPGSANACRWQDVDAILNQGIAVMSAINVQHIREQQPAVEAITGKRAT
RSIPQEFLREADEIEVVDAPPDLSMGDARALAELRELALLLAADVVDHQLQAYLDSHGVSVHWGAQERILVCLTPRSNAL
DMLHSGQRNARRFHGALLVAYVAQVNLSPADQQRLDDNLALARELGAEVHCLPAGDFVDSLLAFAREHRITQLFLGHSQR
ERSPIERLIDAAEDFDIRLFPHGEGK

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=366, Percent_Identity=31.9672131147541, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38814; Mature: 38814

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAPQRRLDPDELLRRVQAEERRERRGRLKVFLGYAPRVGKSLRMFDEGRRRKERGQDV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
VVAAVQEKSTEAVREIIVRLEQLPTVDGAIDLPAVFRRRPSVCLVDELAFDNPPGSANAC
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEHHHHCCCCCCCCCCC
RWQDVDAILNQGIAVMSAINVQHIREQQPAVEAITGKRATRSIPQEFLREADEIEVVDAP
CHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEECC
PDLSMGDARALAELRELALLLAADVVDHQLQAYLDSHGVSVHWGAQERILVCLTPRSNAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHH
DMLHSGQRNARRFHGALLVAYVAQVNLSPADQQRLDDNLALARELGAEVHCLPAGDFVDS
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
LLAFAREHRITQLFLGHSQRERSPIERLIDAAEDFDIRLFPHGEGK
HHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MRSAPQRRLDPDELLRRVQAEERRERRGRLKVFLGYAPRVGKSLRMFDEGRRRKERGQDV
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
VVAAVQEKSTEAVREIIVRLEQLPTVDGAIDLPAVFRRRPSVCLVDELAFDNPPGSANAC
EEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEHHHHCCCCCCCCCCC
RWQDVDAILNQGIAVMSAINVQHIREQQPAVEAITGKRATRSIPQEFLREADEIEVVDAP
CHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEECC
PDLSMGDARALAELRELALLLAADVVDHQLQAYLDSHGVSVHWGAQERILVCLTPRSNAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHH
DMLHSGQRNARRFHGALLVAYVAQVNLSPADQQRLDDNLALARELGAEVHCLPAGDFVDS
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHHH
LLAFAREHRITQLFLGHSQRERSPIERLIDAAEDFDIRLFPHGEGK
HHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]