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The map label for this gene is mnmG

Identifier: 116619160

GI number: 116619160

Start: 20991

End: 22805

Strand: Direct

Name: mnmG

Synonym: Acid_0015

Alternate gene names: 116619160

Gene position: 20991-22805 (Clockwise)

Preceding gene: 116619155

Following gene: 116619161

Centisome position: 0.21

GC content: 62.59

Gene sequence:

>1815_bases
ATGGTAGCAATGCCCGAACGGTACGACGTCGTTGTTATCGGCGCCGGCCACGCCGGCTGCGAAGCGGCGCGCGCCTGTGC
GCGCATCGGCCTGCGCACCGCCATGGTCACCATGAACCTCGACCTGATCGCGCAGATGAGCTGCAACCCCGCGATCGGCG
GCATCGCCAAAGGCCACCTCGTCCGCGAGATCGACGCCTTGGGCGGCGTCATGGGAGAGGTCGCCGATTCCGTCGGCATC
CAGTTCCGCCTGCTGAACACTTCCCGCGGTCCCGCCGTCTGGTCTCCGCGCGCGCAGATGGATAAGAAGCTTTACCGCTT
CCGCATGCGCGAGGTCCTGGAAGCGGAACCCAATTTACGCATCAAGCAGGCTGAGGTGGCTGCCCTGACCTTCGATGCCG
TCCGCCGAGTCAACGGTGTGCTCCTGCGTGACGGCCGCACGATTCCGGCGGGAGCGGTGATCGTCACCACAGGGACTTTC
CTGAACGGCCTGGCACACGTCGGTGAGATGACCTATAGCTGCGGCCGCAACGGCGAAGCGCCCTCCCAACTCTTGGGTGA
CCAACTGCGCAGCATGGGCTTGAACTGGACCCGCTTGAAAACCGGGACACCTCCCCGGCTCGACGGCCGCAGTATCGATT
GGTCCAGTTTCGAGCCTCAGGCCGGTGATGCTGAGCCCACCCCGTTCTCTTTTCTGACTGGCCGGATCGAGCGCCAGCAG
ATCCAGTGTCACATCGGCTACACCACAGACGAAACCCGCCGCGTCCTGCAGGAGGCGATTCCCCGCTCACCTTTATATAG
CGGCCAGATTGAAGGCGTGGGTCCGCGCTATTGTCCGTCGATAGAGGACAAGTTCGTCAAATTCCCGGACAAGGTCCGTC
ACCAGATTTTTCTAGAACCGGAAGGGCTGGATACCCATGAGGTCTACGTGAACGGAATGTCCACCAGCATGCCGACCGAT
GTACAGGTCGCCATGGTTGCCTCCATTCCTGGCCTGGAGCAGGCCGAAATGATCCGCCCGGGCTACGCCATTGAATATGA
TGCGATCGACCCTCGTGAGCTAAACCACACCCTGGAGGTCAAATCGATTCCCGGTCTCTACCTCGCCGGTCAGATCAACG
GCACGTCGGGCTATGAAGAGGCGGGAATCCAGGGTCTCATCGCCGGGTTGAACGCAGCTATGAGCTTGGGAGGCAGCGAC
CCGGTGATCATCGGCCGGACCGAGGGCTACGCCGGAATCCTGGTGGACGACCTGATCACCAAGGGCGCCGACGAACCGTA
CCGGATGTTTACTTCGCGTGCCGAATTTCGCCTTCACCTTCGCATCGATAACGCCGATGCCCGCCTCACTCCCCTCGGCC
GCCGCGCCGGTCTCGCTACCGACGAGCGTTGGGAGCTCTTCCAGCGCAAGGAACGCCAGAAGTTGCGTCTCACGCAGGCC
TTCGAAACCCACAAGAACGGCCAACTGCTGAAGCGCCCTGAGGTCTCGATCAGCGATTTCCTTCCCTGGATCGTGGAAGT
CCTGGGCGAAGCACCCTGTCGCGGACTTCTGGAGACCGTCTCCACTGAGGCCAAATATGGCGGGTACATCCAGCAGCAGG
AGCGCCAGATGGCGCGGATGAAGGACTCCGAGCGCCGCGCTATCCCGCATGGGTTCGAATACAGAGGAATTCCCGGGCTA
TCGCGTGAGATTCAGGACAAGTTGGACAAGGTCCGCCCCGGCACGCTCGGTCAGGCCGGCCGCGTGCCCGGCGTCACGCC
AGCCGCCATCGCTGTGCTGGACTGCTACCTCAGCCTCCACATCGGGCCGAACTAA

Upstream 100 bases:

>100_bases
CGGGGTTGGCGAAAACCTCCACCCCTGGTGACTGCGCCAGCTTCCAGCACAGCGCATGCTCTCGTCCGCCACTGCCGATA
ACCAGTATCTTCACCGTACA

Downstream 100 bases:

>100_bases
TCTGTTTCACGTGAAACAACCTCATTCCCTCACACGAACATCAGCCGTTTTGTTTCACGTGAAACAGCATGCTACCATCA
CCCCTTGAGCCGAGTCTTCG

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHLVREIDALGGVMGEVADSVGI
QFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLRIKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTF
LNGLAHVGEMTYSCGRNGEAPSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQ
IQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEPEGLDTHEVYVNGMSTSMPTD
VQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEVKSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSD
PVIIGRTEGYAGILVDDLITKGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQA
FETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARMKDSERRAIPHGFEYRGIPGL
SREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLHIGPN

Sequences:

>Translated_604_residues
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHLVREIDALGGVMGEVADSVGI
QFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLRIKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTF
LNGLAHVGEMTYSCGRNGEAPSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQ
IQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEPEGLDTHEVYVNGMSTSMPTD
VQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEVKSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSD
PVIIGRTEGYAGILVDDLITKGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQA
FETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARMKDSERRAIPHGFEYRGIPGL
SREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLHIGPN
>Mature_604_residues
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHLVREIDALGGVMGEVADSVGI
QFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLRIKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTF
LNGLAHVGEMTYSCGRNGEAPSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQ
IQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEPEGLDTHEVYVNGMSTSMPTD
VQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEVKSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSD
PVIIGRTEGYAGILVDDLITKGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQA
FETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARMKDSERRAIPHGFEYRGIPGL
SREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLHIGPN

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=628, Percent_Identity=41.7197452229299, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI19882217, Length=653, Percent_Identity=40.1225114854518, Blast_Score=430, Evalue=1e-120,
Organism=Homo sapiens, GI183227703, Length=668, Percent_Identity=39.2215568862275, Blast_Score=425, Evalue=1e-119,
Organism=Escherichia coli, GI2367273, Length=621, Percent_Identity=48.792270531401, Blast_Score=563, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17534255, Length=617, Percent_Identity=41.4910858995138, Blast_Score=457, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6321202, Length=620, Percent_Identity=42.9032258064516, Blast_Score=484, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24658174, Length=635, Percent_Identity=43.4645669291339, Blast_Score=471, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_SOLUE (Q02D35)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_821316.1
- ProteinModelPortal:   Q02D35
- SMR:   Q02D35
- STRING:   Q02D35
- GeneID:   4431703
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0015
- NMPDR:   fig|234267.9.peg.13
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q02D35
- ProtClustDB:   PRK05192
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 66374; Mature: 66374

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 126-126 BINDING 182-182 BINDING 371-371

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECHHHEEECCCCCCCCCCHHHHH
VREIDALGGVMGEVADSVGIQFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLR
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
IKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTFLNGLAHVGEMTYSCGRNGEA
EEHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQ
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEE
IQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEP
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHCCEEEECC
EGLDTHEVYVNGMSTSMPTDVQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEV
CCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHCCCCCEEEECCCCHHHCCCEEEE
KSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSDPVIIGRTEGYAGILVDDLIT
ECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
KGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQA
CCCCCHHHHHHCCCEEEEEEEEECCCCEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARM
HHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KDSERRAIPHGFEYRGIPGLSREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLH
CCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEE
IGPN
ECCC
>Mature Secondary Structure
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHL
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECHHHEEECCCCCCCCCCHHHHH
VREIDALGGVMGEVADSVGIQFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLR
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCE
IKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTFLNGLAHVGEMTYSCGRNGEA
EEHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCC
PSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQ
HHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEE
IQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEP
EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHCCEEEECC
EGLDTHEVYVNGMSTSMPTDVQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEV
CCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHCCCCCEEEECCCCHHHCCCEEEE
KSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSDPVIIGRTEGYAGILVDDLIT
ECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHH
KGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQA
CCCCCHHHHHHCCCEEEEEEEEECCCCEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARM
HHHCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KDSERRAIPHGFEYRGIPGLSREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLH
CCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHEEE
IGPN
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA