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The map label for this gene is gpsA

Identifier: 116516995

GI number: 116516995

Start: 1887250

End: 1888266

Strand: Direct

Name: gpsA

Synonym: SPD_1918

Alternate gene names: 116516995

Gene position: 1887250-1888266 (Clockwise)

Preceding gene: 116515544

Following gene: 116516192

Centisome position: 92.24

GC content: 42.77

Gene sequence:

>1017_bases
ATGGAAAAACAAACCGTCGCCGTCTTGGGGCCTGGTTCTTGGGGAACCGCCCTTTCACAAGTCTTAAATGACAATGGACA
CGAGGTACGTATTTGGGGAAATCTTCCCGAGCAAATCAATGAAATTAATACACACCATACTAATAAGCACTACTTTAAAG
ATGTCGTTCTAGACGAAAATATCATTGCCTACACCGACTTAGCAGAAACATTGAAAAATGTGGATGCGATTTTGTTTGTT
GTCCCAACAAAAGTGACACGACTTGTTGCCCAGCAAGTTGCACAAACCTTGGACCATAAGGTTATCATCATGCACGCATC
AAAGGGATTAGAACCTGATAGCCATAAACGATTATCAACCATTCTTGAAGAAGAAATTCCTGAACATCTCCGTAGTGATA
TCGTCGTTGTTTCAGGGCCTAGTCATGCAGAAGAGACCATTGTGCGTGACCTAACTTTAATAACTGCTGCTTCTAAAGAT
TTACAAACAGCTCAATACGTTCAGGAGCTATTTAGTAATCACTACTTCCGACTTTATACCAATACGGATGTTATCGGGGT
TGAAACTGCTGGTGCTCTTAAAAATATTATTGCTGTCGGTGCTGGAGCTTTACATGGTCTTGGATTTGGTGATAATGCTA
AGGCAGCCATCATCGCTCGAGGTTTAGCAGAAATCACCCGCCTAGGGGTAGCACTCGGGGCCAGTCCATTGACCTATAGC
GGCTTATCTGGTGTGGGAGATTTGATCGTAACGGGAACTTCCATCCACTCTCGTAACTGGAGAGCTGGAGATGCTCTCGG
ACGAGGAGAATCCCTAGCTGATATAGAAGCTAATATGGGCATGGTAATCGAAGGAATTTCAACGACTCGAGCAGCCTATG
AACTAGCCCAAGAACTTGGAGTCTATATGCCCATTACACAGGCTATTTACCAAGTTATTTATCACGGAACCAATATCAAA
GATGCCATTTATGACATCATGAACAATGAATTTAAAGCAGAAAATGAGTGGTCTTAA

Upstream 100 bases:

>100_bases
TCGGTCTTTGTGTATTTTTCCACCATACCCCAGTAATGCAAGTGCAAAATCCCCTAGAATATGATAGAATAAGAGAAAGA
AATCTATCAAGGAGGAAATC

Downstream 100 bases:

>100_bases
CCCTCTATAGAAAGGATTTTTATGACATCAAAAGTTAGAAAGGCAGTTATCCCTGCTGCTGGACTAGGAACTCGATTTTT
ACCAGCAACCAAGGCCCTTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS

Sequences:

>Translated_338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS
>Mature_338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=353, Percent_Identity=30.3116147308782, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI24307999, Length=341, Percent_Identity=29.3255131964809, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=40.0602409638554, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32564399, Length=337, Percent_Identity=27.893175074184, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=345, Percent_Identity=27.8260869565217, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=345, Percent_Identity=27.8260869565217, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=26.7045454545455, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI193210134, Length=337, Percent_Identity=25.2225519287834, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=347, Percent_Identity=29.3948126801153, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=29.3948126801153, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17136202, Length=353, Percent_Identity=28.328611898017, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136200, Length=346, Percent_Identity=28.6127167630058, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136204, Length=346, Percent_Identity=28.6127167630058, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI22026922, Length=295, Percent_Identity=24.406779661017, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551945, Length=293, Percent_Identity=23.8907849829352, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281362270, Length=293, Percent_Identity=23.8907849829352, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648969, Length=239, Percent_Identity=25.5230125523013, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_STRP2 (Q04I82)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_817306.1
- ProteinModelPortal:   Q04I82
- SMR:   Q04I82
- STRING:   Q04I82
- EnsemblBacteria:   EBSTRT00000019041
- GeneID:   4441977
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1918
- eggNOG:   COG0240
- GeneTree:   EBGT00050000027944
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36777; Mature: 36777

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 194-194 BINDING 108-108 BINDING 108-108 BINDING 143-143 BINDING 258-258 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDEN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCC
IIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLST
EEEHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
ILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYT
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHCC
VYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDEN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCC
IIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLST
EEEHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
ILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYT
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHCC
VYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA