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The map label for this gene is trxB [H]

Identifier: 116516912

GI number: 116516912

Start: 1309717

End: 1310628

Strand: Reverse

Name: trxB [H]

Synonym: SPD_1287

Alternate gene names: 116516912

Gene position: 1310628-1309717 (Counterclockwise)

Preceding gene: 116516132

Following gene: 116516365

Centisome position: 64.05

GC content: 42.43

Gene sequence:

>912_bases
ATGTACGATACTATTATTATCGGTGCTGGACCTGCAGGGATGACTGCGGCCTTGTATGCTGCTCGAAGCAATCTAAAAGT
AGCTTTGATTGAAGGTGGTCTGCCAGGTGGTCAGATGAATAATACATCTGATATCGAAAATTACCCAGGATACGCTAATA
TTAGTGGACCTGAATTGGCTGAAAAGATGTTTGAACCACTTGAAAATCTTGGTGTTGAGCACATTTATGGTTATGTTGAA
AATGTCGAAGACCATGGTGATTTTAAGAAAGTGATGACTGATGACCAAACATATGAAACACGTACAGTTATCGTAGCAAC
TGGTTCTAAACACCGTCCTTTGGGAGTACCTGGAGAAGAAGAACTGAACAGTCGTGGTGTTTCTTACTGTGCTGTGTGTG
ATGGTGCTTTCTTCCGTGACCAAGATTTATTGGTAGTTGGTGGTGGAGATTCAGCTGTTGAAGAAGCCCTCTTCTTGACT
CGTTTTGCTAAGACTGTTACCATTGTTCACCGTCGTGACCAACTTCGTGCCCAAAAGGTTTTACAAGATCGCGCCTTTGC
GAATGAAAAAATCAGCTTTATCTGGGATTCTGTAGTGAAGGAAATCAAGGGTGAAAACAGAGTAGAATCTGTCGTTTTTG
AAAATGTGAAAACAGGTCAAGTGACAGAGCAAGCCTTCGGTGGTGTCTTTATCTATGTTGGTTTGGACCCTCTTAGCGAT
TTTGTTAAAGAATTGAATATCCAAGATCAGGCAGGCTGGATTGTGACAGATAGCCACATGAAGACTGCAGTCGACGGTAT
CTTTGCAGTTGGAGATGTTCGCTTGAAAGACCTTCGCCAAGTAACAACAGCAGTTGGAGATGGAGCTATCGCTGGTCAAG
AAGCCTACAAGTTTATCACAGAACATAGTTAA

Upstream 100 bases:

>100_bases
CGGTTATGAGTTTAATTCTTGTTTTCAAGGCATAATCCTTGCGTGATTGACAAGAAAGAGTTAGAATAAAGATAGTTACA
ACAAGAAAGAAGGAATCTAT

Downstream 100 bases:

>100_bases
TCATAAAAAAGTTTCCAATCAGATGACTGGAAACTTTTTTATAGTCTATTTCGGAAAACTTCGTACATGAGAATGGCCGC
AGCAACACTGGCATTAAGGC

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Sequences:

>Translated_303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS
>Mature_303_residues
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVE
NVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
FVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=306, Percent_Identity=36.2745098039216, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=30.9210526315789, Blast_Score=146, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320560, Length=309, Percent_Identity=38.5113268608414, Blast_Score=202, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=36.741214057508, Blast_Score=192, Evalue=6e-50,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33093; Mature: 33093

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELA
CCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
EKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEE
HHHHHHHHHCCHHHHHHHHHCCHHCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
ELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKV
HHHCCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCHHHH
FVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFIT
HHHHCCCCCCCCEEEECCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHS
CCC
>Mature Secondary Structure
MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELA
CCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
EKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEE
HHHHHHHHHCCHHHHHHHHHCCHHCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHH
ELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKV
HHHCCCCEEEEEECCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSD
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCHHHH
FVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFIT
HHHHCCCCCCCCEEEECCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]