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The map label for this gene is asnC [H]

Identifier: 116515635

GI number: 116515635

Start: 1383297

End: 1384640

Strand: Reverse

Name: asnC [H]

Synonym: SPD_1371

Alternate gene names: 116515635

Gene position: 1384640-1383297 (Counterclockwise)

Preceding gene: 116515820

Following gene: 116516740

Centisome position: 67.67

GC content: 43.82

Gene sequence:

>1344_bases
ATGACAAAACGTGTAACGATTATTGATGTAAAAGACTATGTTGGTCAGGAAGTGACGATTGGCGCTTGGGTTGCCAACAA
ATCAGGAAAAGGGAAAATCGCTTTCTTACAATTGCGTGATGGAACAGCCTTCTTTCAAGGTGTGGCTTTTAAACCAAACT
TTGTCGAAAAATTTGGTGAAGAAGTGGGACTTGAGAAGTTTGATGTTATCAAACGCTTGAGCCAAGAAACGTCTGTTTAT
GTGACAGGTATTGTCAAAGAGGACGAACGTTCTAAATTTGGCTATGAGTTGGACATCACAGACATCGAAGTGATCGGTGA
ATCTCAAGACTACCCAATCACACCAAAAGAACACGGAACAGACTTTTTGATGGATAACCGTCACTTGTGGCTACGCTCTC
GTAAGCAAGTAGCTGTGTTGCAAATCCGTAACGCTATTATCTATGTAACTTATGAGTTCTTTGACAAGAATGGTTTTATG
AAGTTTGACAGCCCAATTCTTTCAGGAAATGCGGCAGAAGATTCTACAGAACTCTTTGAAACTGACTACTTCGGAACGCC
AGCCTACTTGAGCCAATCAGGTCAGCTTTACCTAGAAGCAGGGGCTATGGCTCTTGGTCGTGTCTTTGACTTTGGTCCAG
TTTTCCGTGCTGAAAAATCAAAAACACGCCGTCACTTGACTGAGTTCTGGATGATGGATGCTGAGTACTCATACTTGACA
CATGATGAGTCGCTTGACTTGCAAGAAGCTTATGTGAAAGCTCTTCTACAAGGTGTTCTTGACCGCGCGCCTCAAGCCTT
GGAAACCTTGGAACGTGATACAGAACTCTTGAAACGCTACATTGCAGAGCCATTCAAACGTATCACTTACGATCAAGCCA
TTGACCTCTTGCAAGAGCATGAAAATGATGAAGATGCTGACTACGAGCATCTTGAGCATGGTGATGACTTTGGGTCACCA
CACGAAACTTGGATTTCAAACCACTTTGGTGTGCCAACATTTGTCATGAACTATCCAGCAGCCATCAAGGCCTTCTACAT
GAAACCAGTTCCTGGAAATCCAGAGCGCGTGCTTTGTGCAGACTTGCTTGCTCCAGAAGGCTATGGAGAAATTATCGGTG
GGTCTATGCGTGAGGAAGATTACGATGCCCTTGTCGCTAAGATGGATGAACTTGGCATGGATCGTACAGAATATGAATTC
TACCTTGACCTTCGTAAATACGGTACAGTTCCACACGGAGGATTTGGTATCGGTATCGAACGTATGGTAACCTTCGCAGC
AGGAACAAAACATATCCGTGAAGCTATTCCATTCCCACGTATGTTGCACCGTATCAAACCATAA

Upstream 100 bases:

>100_bases
AAGTGAGCATCCGATTTATTATGCTGCTTTTATGATTGACCTGGATGGGAACAATATAGAGGTGGTTTGCCATAAAGAAT
AAAAAAGAAAAGGAAAAATA

Downstream 100 bases:

>100_bases
GAACAGGAAAACGCCCATGTGGCGTTTTTTCGAATTCTAGTGTTTTTACTTGCGTAAAAAAATTTTTTCTAGTATAATAG
TTTATTGTGAGCGAACCTCA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVY
VTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFM
KFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLT
HDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSP
HETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEF
YLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP

Sequences:

>Translated_447_residues
MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVY
VTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFM
KFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLT
HDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSP
HETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEF
YLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP
>Mature_446_residues
TKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYV
TGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFMK
FDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLTH
DESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPH
ETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFY
LDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=460, Percent_Identity=32.6086956521739, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=34.7252747252747, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI45439306, Length=485, Percent_Identity=27.0103092783505, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1787161, Length=457, Percent_Identity=34.5733041575492, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1788173, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789256, Length=458, Percent_Identity=23.3624454148472, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71984122, Length=441, Percent_Identity=36.9614512471655, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17556372, Length=427, Percent_Identity=30.4449648711944, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17551876, Length=492, Percent_Identity=27.2357723577236, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321807, Length=453, Percent_Identity=34.6578366445916, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6319872, Length=467, Percent_Identity=32.5481798715203, Blast_Score=235, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6323011, Length=490, Percent_Identity=29.7959183673469, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI19922416, Length=476, Percent_Identity=30.672268907563, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI19921528, Length=437, Percent_Identity=33.8672768878719, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI17136276, Length=336, Percent_Identity=28.8690476190476, Blast_Score=138, Evalue=9e-33,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 51095; Mature: 50964

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGE
CCCEEEEEEEHHHCCCEEEEEEEEECCCCCCCEEEEEEECCCHHHCCCCCCCHHHHHHHH
EVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGT
HHCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCC
DFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFMKFDSPILSGNAAEDSTELFE
CEEECCCEEEECCCCCEEEEEECCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHH
TDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLT
CCCCCCCHHHCCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEC
HDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEH
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ENDEDADYEHLEHGDDFGSPHETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCA
CCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCCCHHHEEEEECCCCCCCCCEEEH
DLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFYLDLRKYGTVPHGGFGIGIE
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCHH
RMVTFAAGTKHIREAIPFPRMLHRIKP
HHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGE
CCEEEEEEEHHHCCCEEEEEEEEECCCCCCCEEEEEEECCCHHHCCCCCCCHHHHHHHH
EVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGT
HHCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCC
DFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFMKFDSPILSGNAAEDSTELFE
CEEECCCEEEECCCCCEEEEEECCEEEEEEEEEECCCCCEEECCCCCCCCCCCCCHHHHH
TDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLT
CCCCCCCHHHCCCCCEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEC
HDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEH
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ENDEDADYEHLEHGDDFGSPHETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCA
CCCCCCCHHHHHCCCCCCCCHHHHHHCCCCCCHHHHCCCHHHEEEEECCCCCCCCCEEEH
DLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFYLDLRKYGTVPHGGFGIGIE
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCHH
RMVTFAAGTKHIREAIPFPRMLHRIKP
HHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA