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The map label for this gene is ywfO [H]

Identifier: 116496007

GI number: 116496007

Start: 2557105

End: 2558457

Strand: Direct

Name: ywfO [H]

Synonym: LSEI_2576

Alternate gene names: 116496007

Gene position: 2557105-2558457 (Clockwise)

Preceding gene: 116496006

Following gene: 116496009

Centisome position: 88.32

GC content: 46.93

Gene sequence:

>1353_bases
ATGCTATTTGAAAAGTTACCTCGCGAAAAAGTCTTTCGCGATCCAGTTCATAATTATGTCCATGTGCAACATCGCGTCAT
TCTGGACCTGATTAATACCCCAGAATTTCAGCGATTACGCCGCATTAAACAGCTCGGCGTTTCTGATTATGTTTTTCAAG
GCGCCGAACATACTAGGTTTGCCCATTCACTTGGTGTTTATGAAATTGCCCGTGAGATGTGTGACAACTTTGTCAACAAC
TATCCGACACAAACACCTGGCGATGGCCTATGGGATGACGCCGAACGGCCAGTCGTGTTATGTGCCGCCTTGCTGCACGA
TATCGGCCATGGTGCCTATTCGCATACATTTGAGCACATTTTCGACACTGATCACGAGGCGATTACGCGAGCAATTCTCA
CGGATTCGCATACGAACGTGAACAAAATTCTGCGTGGTGTCGGTCCGGAATTTCCTGAGATGGTCGCATCGGTTATCAAC
CACACCTATCCGAATCCGCAAGTCGTGCAAATGATCTCCAGTCAGATTGATGCTGATCGGATGGATTATTTGTTGCACGA
TGCTTATTACACCGGCACGAAGTATGGTCTCTTCGACCTTTCGCGAATTCTGCGAGTCATGCGACCATACTCGGATGGCA
TCGCTTATGAAGCCAACGGCATGCATGCGGTCGAAGATTATGTTGTCAGTCGGTTTCAGATGTACCAGCAGGTTTATTTC
CACCCTGTGTCTCGTGGCATGGAAGTCATTCTTTTCCATCTGCTAAAACGTGCCAAATTCCTGTATGAGTCCGGTCAGTT
TGAATCTGGCTTTTCGCCGCGGCTACTCGTGCCATTTTTTGAACAAACTTTTAACCTCACCGACTATTTGAAACTCGACG
ATGGCGTGTTAAACACTTACTTCACTTACTGGCTAGATTATCCAGACAGTATCTTAAGCGATTTTGCTGATCGCTTCTTG
AACCGCCGACCACTGAAGTCTGTGACCTTTACTGACCAAACAGCCTATCTCTTGCCACGCTTAAGGGATTTGGTAGCATC
AGCCGGCTTTGACCCGCACTACTACACAGCGGAAAATGATAGTTTTGACTTACCATATGACCAATACGACCCAGCTTCCG
CAAATCCAAAAACGCAAATCGAGATCATGCAAAAAGATGGGACGCTTGAGGAGCTCTCCACCCTATCACCGTTAGTCGCG
GCACTTAGCGGTCGGGCAACCGGTGACAAACGGTTCTACTTTCCAAAAGAAATGCTAGCCACGCAAGACAGTAACCTGTT
TTCGCCAATTTATGAAAAGTTCCAGCATTATCTGCTGAATGGCGGTCTCATTGATCCACACTTTAACGATTGA

Upstream 100 bases:

>100_bases
CCAACCCTTTTGCGCGATCCAGCTTACCATAAGGCGCTGACAGAAGCGACTGCCGATTTGCACACGCGCAATCGCAGCCT
AAAAAAGATGGGAGAACATG

Downstream 100 bases:

>100_bases
TGACTGCCTTATCGCTTAGGTTGATTGGCTAGCCATTTGGCAACTGCCCAACGGTGGGTCGGTCGTTTCAGCTCAGCGAT
GGCTAGGTCAATCGGCATTA

Product: HD superfamily phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MLFEKLPREKVFRDPVHNYVHVQHRVILDLINTPEFQRLRRIKQLGVSDYVFQGAEHTRFAHSLGVYEIAREMCDNFVNN
YPTQTPGDGLWDDAERPVVLCAALLHDIGHGAYSHTFEHIFDTDHEAITRAILTDSHTNVNKILRGVGPEFPEMVASVIN
HTYPNPQVVQMISSQIDADRMDYLLHDAYYTGTKYGLFDLSRILRVMRPYSDGIAYEANGMHAVEDYVVSRFQMYQQVYF
HPVSRGMEVILFHLLKRAKFLYESGQFESGFSPRLLVPFFEQTFNLTDYLKLDDGVLNTYFTYWLDYPDSILSDFADRFL
NRRPLKSVTFTDQTAYLLPRLRDLVASAGFDPHYYTAENDSFDLPYDQYDPASANPKTQIEIMQKDGTLEELSTLSPLVA
ALSGRATGDKRFYFPKEMLATQDSNLFSPIYEKFQHYLLNGGLIDPHFND

Sequences:

>Translated_450_residues
MLFEKLPREKVFRDPVHNYVHVQHRVILDLINTPEFQRLRRIKQLGVSDYVFQGAEHTRFAHSLGVYEIAREMCDNFVNN
YPTQTPGDGLWDDAERPVVLCAALLHDIGHGAYSHTFEHIFDTDHEAITRAILTDSHTNVNKILRGVGPEFPEMVASVIN
HTYPNPQVVQMISSQIDADRMDYLLHDAYYTGTKYGLFDLSRILRVMRPYSDGIAYEANGMHAVEDYVVSRFQMYQQVYF
HPVSRGMEVILFHLLKRAKFLYESGQFESGFSPRLLVPFFEQTFNLTDYLKLDDGVLNTYFTYWLDYPDSILSDFADRFL
NRRPLKSVTFTDQTAYLLPRLRDLVASAGFDPHYYTAENDSFDLPYDQYDPASANPKTQIEIMQKDGTLEELSTLSPLVA
ALSGRATGDKRFYFPKEMLATQDSNLFSPIYEKFQHYLLNGGLIDPHFND
>Mature_450_residues
MLFEKLPREKVFRDPVHNYVHVQHRVILDLINTPEFQRLRRIKQLGVSDYVFQGAEHTRFAHSLGVYEIAREMCDNFVNN
YPTQTPGDGLWDDAERPVVLCAALLHDIGHGAYSHTFEHIFDTDHEAITRAILTDSHTNVNKILRGVGPEFPEMVASVIN
HTYPNPQVVQMISSQIDADRMDYLLHDAYYTGTKYGLFDLSRILRVMRPYSDGIAYEANGMHAVEDYVVSRFQMYQQVYF
HPVSRGMEVILFHLLKRAKFLYESGQFESGFSPRLLVPFFEQTFNLTDYLKLDDGVLNTYFTYWLDYPDSILSDFADRFL
NRRPLKSVTFTDQTAYLLPRLRDLVASAGFDPHYYTAENDSFDLPYDQYDPASANPKTQIEIMQKDGTLEELSTLSPLVA
ALSGRATGDKRFYFPKEMLATQDSNLFSPIYEKFQHYLLNGGLIDPHFND

Specific function: Unknown

COG id: COG1078

COG function: function code R; HD superfamily phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Homo sapiens, GI38016914, Length=115, Percent_Identity=43.4782608695652, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537827, Length=363, Percent_Identity=26.9972451790634, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17537829, Length=363, Percent_Identity=26.9972451790634, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24666702, Length=271, Percent_Identity=26.9372693726937, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221512937, Length=271, Percent_Identity=26.9372693726937, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52022; Mature: 52022

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 7934828 [H]