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The map label for this gene is ptxC [H]

Identifier: 116495891

GI number: 116495891

Start: 2432941

End: 2433723

Strand: Direct

Name: ptxC [H]

Synonym: LSEI_2447

Alternate gene names: 116495891

Gene position: 2432941-2433723 (Clockwise)

Preceding gene: 116495890

Following gene: 116495892

Centisome position: 84.03

GC content: 44.83

Gene sequence:

>783_bases
ATGACAGCTCCTACGTTACCGAAACGTCAGCTGCAATGGCGCAAGTGGCTGCTGACTGGCATCATGGTACTTGGTTTAAT
TTGGTCGATTGGGATCACCAATGCAAATCTCGGGTTGTTTTTCAAGAATTTCAGTCAATTCACTGTCATTTTTACCGAAA
TGGCGCATGTTGACTGGAGTTACGCTTATTACACAATCGATCCGATGATTCAGACATTGAAAATGGCAATCATTGGCACC
TTGATTGGCTCTGCCGTTGCTTTTCCATATGCCCTTTTAGTTTCGCGCAACATTGTGACTAATAAAATTGTGGTAGGCAT
TTTTCGCTTTGTGCTCAATATTGTCCGTACCATCCCCGATCTCATGTTAGCGGCACTTTTTGTCGCCATTGTCGGAATCG
GACCAGTGGCCGGTATTTTTGCGTTAGCGATCTTTACTTTTGGGATGGTTGGCAAGCTGTTTTATGAAGCAGTTGAAACG
ATTGATCCTGGACCGCTTGAAGCACTTAAGGCAGCAGGTGCAGGCCGAATTGAAATGATTCGTTTTGCAGTGTTGCCGCA
GATCGCAAATTATTTTGTTAGCTTCGTCTTGTATGCTTTCGAAATTAACGTTCGGGCTAGTACGGTGCTCGGCTATATGG
GAGCTGGCGGGATCGGTATTTACTTGCAACAGGCATTATCCATGTTTCGGTATGATCGGGTCGGTTTGATTGTGCTAGTT
ATCTTTGCTGTTGTACTTGTCATTGACTACATTAGCGGTAAGGCTAGGGAGGTGCTTCTATGA

Upstream 100 bases:

>100_bases
GTATTCGGGCGGGGCAAAAAGTGTTTGACGGTCCGGTTGCCGAAGCCACTGATGAAATCATAGCTAGTATTTACAGCGGT
AATGAGCAGGAGGTGTCATA

Downstream 100 bases:

>100_bases
ATCACTCAGCTTCATTGCCAAAGGCCCCCCTGCAACATCGTTGGCGCAATTGGTTACTGACAATAATCACCTTAGCGATT
ATCGTTTGGTCATTCACAGG

Product: ABC-type phosphate/phosphonate transport system, permease component

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTAPTLPKRQLQWRKWLLTGIMVLGLIWSIGITNANLGLFFKNFSQFTVIFTEMAHVDWSYAYYTIDPMIQTLKMAIIGT
LIGSAVAFPYALLVSRNIVTNKIVVGIFRFVLNIVRTIPDLMLAALFVAIVGIGPVAGIFALAIFTFGMVGKLFYEAVET
IDPGPLEALKAAGAGRIEMIRFAVLPQIANYFVSFVLYAFEINVRASTVLGYMGAGGIGIYLQQALSMFRYDRVGLIVLV
IFAVVLVIDYISGKAREVLL

Sequences:

>Translated_260_residues
MTAPTLPKRQLQWRKWLLTGIMVLGLIWSIGITNANLGLFFKNFSQFTVIFTEMAHVDWSYAYYTIDPMIQTLKMAIIGT
LIGSAVAFPYALLVSRNIVTNKIVVGIFRFVLNIVRTIPDLMLAALFVAIVGIGPVAGIFALAIFTFGMVGKLFYEAVET
IDPGPLEALKAAGAGRIEMIRFAVLPQIANYFVSFVLYAFEINVRASTVLGYMGAGGIGIYLQQALSMFRYDRVGLIVLV
IFAVVLVIDYISGKAREVLL
>Mature_259_residues
TAPTLPKRQLQWRKWLLTGIMVLGLIWSIGITNANLGLFFKNFSQFTVIFTEMAHVDWSYAYYTIDPMIQTLKMAIIGTL
IGSAVAFPYALLVSRNIVTNKIVVGIFRFVLNIVRTIPDLMLAALFVAIVGIGPVAGIFALAIFTFGMVGKLFYEAVETI
DPGPLEALKAAGAGRIEMIRFAVLPQIANYFVSFVLYAFEINVRASTVLGYMGAGGIGIYLQQALSMFRYDRVGLIVLVI
FAVVLVIDYISGKAREVLL

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28665; Mature: 28534

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
TAPTLPKRQLQWRKWLLTGIMVLGLIWSIGITNANLGLFFKNFSQFTVIFTEMAHVDWS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
YAYYTIDPMIQTLKMAIIGTLIGSAVAFPYALLVSRNIVTNKIVVGIFRFVLNIVRTIPD
HHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LMLAALFVAIVGIGPVAGIFALAIFTFGMVGKLFYEAVETIDPGPLEALKAAGAGRIEMI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHH
RFAVLPQIANYFVSFVLYAFEINVRASTVLGYMGAGGIGIYLQQALSMFRYDRVGLIVLV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IFAVVLVIDYISGKAREVLL
HHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]