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The map label for this gene is hexR [H]

Identifier: 116495768

GI number: 116495768

Start: 2313102

End: 2313932

Strand: Direct

Name: hexR [H]

Synonym: LSEI_2316

Alternate gene names: 116495768

Gene position: 2313102-2313932 (Clockwise)

Preceding gene: 116495756

Following gene: 116495778

Centisome position: 79.89

GC content: 47.05

Gene sequence:

>831_bases
ATGAGTATTATTGACCGTCTTTATAGCATGCTGCCAACACTGACCGCGACTGACCGTAAGATTGCGCAGGTTCTTCTGAC
GAATCCCGGTGCTGTCGTGAATACCACCATCGCCGCCCTCGCAAAAGAAAGTAACGTTAGCGAAGCCTCAATTTCTCGTT
TTTGCCGGACAATTGGTGTTGAAGGCTTTCATCAACTCAAGATTGAGCTTGCTAAGGTTGCTGAAAACCGTAGTGCGTAT
TATCAGGAAATTAACGCCGACAATCTTCAGCAAGCCTTAAGCAATATCAGTGCCAACAAAGTCGCCGAAATCGAAGGCAC
ACTAAAAAACGCCAGCTCACATGACATTCGAAAAATTTTGGATTTGTTAAAACAAGCTAGTGTAATTTTAGTCGCCGCTG
CTGGCGATACGCAGCCGGTTGCCGATGACGCCGTCTATAAATTCAATCAACTCGGTCTACTAGCCATCACAGACAGTTCT
TGGGAAACGGCGCTCGCCCAAACCATGAATGCACCTGCAGATGCTTTGTTGCTGGTTATCTCAAATTCTGGCGAAACGCG
GAATCTCATCACCCAAATCAAAGCCGCTCAACAACGTGGTATTGCTGTGGTCGCGATTACCAATCGCAAGGATTCACCGA
TTGGCTTGGCCGCCGATTATCAGCTTTTGACCGCGGTTCGGCAGCAAATTTTCGAGTCCGAATATTTCTTCTCACGCGTT
GCCGCCATGACGGCGGTGGAAGCCTTATTCTTGTTGCTTCTAGCTGAGGATAAAACTTTCATGGCACATATTAAGGCTCA
TGAAGCATTGATTGCGGAGACTAAGATTTAG

Upstream 100 bases:

>100_bases
AGTTGTGCGGATTGTCTTTTAAAATTAATCGCGTAGAATAAAGGCCGGAGAGTTTCATAAAACAGATTATTCAGAAATTT
AATTGAAAAGGAGCTGTGTT

Downstream 100 bases:

>100_bases
GTGTTCGTCTTAGGCCGACTCTTATCATTTAAAAATGACATTTCTTCTAAAAAAGAGGGATGATTTTTCCGTAACACAGA
AAAATCATCCCTCTTTATTT

Product: transcriptional regulator

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSIIDRLYSMLPTLTATDRKIAQVLLTNPGAVVNTTIAALAKESNVSEASISRFCRTIGVEGFHQLKIELAKVAENRSAY
YQEINADNLQQALSNISANKVAEIEGTLKNASSHDIRKILDLLKQASVILVAAAGDTQPVADDAVYKFNQLGLLAITDSS
WETALAQTMNAPADALLLVISNSGETRNLITQIKAAQQRGIAVVAITNRKDSPIGLAADYQLLTAVRQQIFESEYFFSRV
AAMTAVEALFLLLLAEDKTFMAHIKAHEALIAETKI

Sequences:

>Translated_276_residues
MSIIDRLYSMLPTLTATDRKIAQVLLTNPGAVVNTTIAALAKESNVSEASISRFCRTIGVEGFHQLKIELAKVAENRSAY
YQEINADNLQQALSNISANKVAEIEGTLKNASSHDIRKILDLLKQASVILVAAAGDTQPVADDAVYKFNQLGLLAITDSS
WETALAQTMNAPADALLLVISNSGETRNLITQIKAAQQRGIAVVAITNRKDSPIGLAADYQLLTAVRQQIFESEYFFSRV
AAMTAVEALFLLLLAEDKTFMAHIKAHEALIAETKI
>Mature_275_residues
SIIDRLYSMLPTLTATDRKIAQVLLTNPGAVVNTTIAALAKESNVSEASISRFCRTIGVEGFHQLKIELAKVAENRSAYY
QEINADNLQQALSNISANKVAEIEGTLKNASSHDIRKILDLLKQASVILVAAAGDTQPVADDAVYKFNQLGLLAITDSSW
ETALAQTMNAPADALLLVISNSGETRNLITQIKAAQQRGIAVVAITNRKDSPIGLAADYQLLTAVRQQIFESEYFFSRVA
AMTAVEALFLLLLAEDKTFMAHIKAHEALIAETKI

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=251, Percent_Identity=27.0916334661355, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788767, Length=255, Percent_Identity=24.3137254901961, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082130, Length=278, Percent_Identity=24.4604316546763, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 29916; Mature: 29784

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIDRLYSMLPTLTATDRKIAQVLLTNPGAVVNTTIAALAKESNVSEASISRFCRTIGV
CCHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGFHQLKIELAKVAENRSAYYQEINADNLQQALSNISANKVAEIEGTLKNASSHDIRKIL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
DLLKQASVILVAAAGDTQPVADDAVYKFNQLGLLAITDSSWETALAQTMNAPADALLLVI
HHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEE
SNSGETRNLITQIKAAQQRGIAVVAITNRKDSPIGLAADYQLLTAVRQQIFESEYFFSRV
ECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAMTAVEALFLLLLAEDKTFMAHIKAHEALIAETKI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIIDRLYSMLPTLTATDRKIAQVLLTNPGAVVNTTIAALAKESNVSEASISRFCRTIGV
CHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGFHQLKIELAKVAENRSAYYQEINADNLQQALSNISANKVAEIEGTLKNASSHDIRKIL
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
DLLKQASVILVAAAGDTQPVADDAVYKFNQLGLLAITDSSWETALAQTMNAPADALLLVI
HHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCEEEEEE
SNSGETRNLITQIKAAQQRGIAVVAITNRKDSPIGLAADYQLLTAVRQQIFESEYFFSRV
ECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAMTAVEALFLLLLAEDKTFMAHIKAHEALIAETKI
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]