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The map label for this gene is yhcG [H]

Identifier: 116495348

GI number: 116495348

Start: 1875213

End: 1875926

Strand: Direct

Name: yhcG [H]

Synonym: LSEI_1881

Alternate gene names: 116495348

Gene position: 1875213-1875926 (Clockwise)

Preceding gene: 116495347

Following gene: 116495349

Centisome position: 64.77

GC content: 43.42

Gene sequence:

>714_bases
ATGACAACTAACATGATCACAGTCAAACAATTGACTTATAAACGCAATCGTAAAGTGATTCTAGACGACTTGAATCTTGA
CCTCGTTCAAGGTCACTTCATCGGCTTATTAGGTGCAAACGGTGCCGGCAAAACCACATTGATGCGACTGTTAAACGGGG
TCGCGACCACTTTTCATGGCACCATTCAAATTGGCTCATCAGAAAGTATTGTTGAACGGAAACAACTAAGCAGCTTCAGT
GAGTCGTTAAATGGCGTCAACCCAAATCGAACGCTCAAGCAAATTGCCACTTATTATGCCGACATGTATCTTGATTTTTC
TGAAGCCGAGTTTGCTAACTTCCTGAAGACATTTGATCTTGATTCCCACCAGAAGCTGGCGGCCCTGTCAAAAGGTAATC
GCAAAAAATTGATCGCTGCACTGACCCTTGCCCGCCAAACTCAACTTTATCTGCTAGATGAACCTTTTGAAGGTATCGAT
AGCATGACGCGCAAACGGATCATCAGTAACTTGATTGCGTGGAAACCGGCAGCGGCAACTGTGATTATTTCGGATCATCA
CGTAAGCGACGTTGCCAATGTGTTGGATGAGGTTGTCATCATTAAAGACAAGCACGTGGTGGCACAAAAAAATGCCGAAG
AGTTGCGAGAAAAAACCGGCATGAGTATTGAAAACTATTATGAAAGTTTCTATGAAGGAAGTGACCAACAATGA

Upstream 100 bases:

>100_bases
GAATTAGATCGCCTTTATCACCAACTATCAGAATTGAATTTAAGTGATGAGGAAATGAAAGACGCATTCGCCGCTTATGT
TGATGAGCAGGAGGTAAAAC

Downstream 100 bases:

>100_bases
CTAATACATGGACAATGATGCGAACCTTGACCCGGCAACGTTCACTAACAGCATTTAAAACATTCATCGTGACTTTGGTT
GCGACCGTTGTATCAATCCT

Product: ABC transporter ATPase

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTTNMITVKQLTYKRNRKVILDDLNLDLVQGHFIGLLGANGAGKTTLMRLLNGVATTFHGTIQIGSSESIVERKQLSSFS
ESLNGVNPNRTLKQIATYYADMYLDFSEAEFANFLKTFDLDSHQKLAALSKGNRKKLIAALTLARQTQLYLLDEPFEGID
SMTRKRIISNLIAWKPAAATVIISDHHVSDVANVLDEVVIIKDKHVVAQKNAEELREKTGMSIENYYESFYEGSDQQ

Sequences:

>Translated_237_residues
MTTNMITVKQLTYKRNRKVILDDLNLDLVQGHFIGLLGANGAGKTTLMRLLNGVATTFHGTIQIGSSESIVERKQLSSFS
ESLNGVNPNRTLKQIATYYADMYLDFSEAEFANFLKTFDLDSHQKLAALSKGNRKKLIAALTLARQTQLYLLDEPFEGID
SMTRKRIISNLIAWKPAAATVIISDHHVSDVANVLDEVVIIKDKHVVAQKNAEELREKTGMSIENYYESFYEGSDQQ
>Mature_236_residues
TTNMITVKQLTYKRNRKVILDDLNLDLVQGHFIGLLGANGAGKTTLMRLLNGVATTFHGTIQIGSSESIVERKQLSSFSE
SLNGVNPNRTLKQIATYYADMYLDFSEAEFANFLKTFDLDSHQKLAALSKGNRKKLIAALTLARQTQLYLLDEPFEGIDS
MTRKRIISNLIAWKPAAATVIISDHHVSDVANVLDEVVIIKDKHVVAQKNAEELREKTGMSIENYYESFYEGSDQQ

Specific function: Part Of A Binding-Protein-Dependent Transport System For Taurine. Probably Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21536376, Length=223, Percent_Identity=29.5964125560538, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI47078218, Length=208, Percent_Identity=27.8846153846154, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI45446740, Length=208, Percent_Identity=27.8846153846154, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI27262624, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27436953, Length=215, Percent_Identity=25.1162790697674, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI153792144, Length=231, Percent_Identity=22.9437229437229, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI116734710, Length=227, Percent_Identity=23.7885462555066, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI105990541, Length=210, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31657092, Length=221, Percent_Identity=26.2443438914027, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=215, Percent_Identity=27.4418604651163, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789586, Length=261, Percent_Identity=22.6053639846743, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=244, Percent_Identity=25, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI2367384, Length=201, Percent_Identity=26.3681592039801, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789751, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=223, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790739, Length=209, Percent_Identity=24.4019138755981, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786653, Length=246, Percent_Identity=22.7642276422764, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=229, Percent_Identity=24.8908296943231, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=212, Percent_Identity=25.9433962264151, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=24, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1786253, Length=208, Percent_Identity=24.5192307692308, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=225, Percent_Identity=21.7777777777778, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787182, Length=204, Percent_Identity=24.5098039215686, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788165, Length=159, Percent_Identity=26.4150943396226, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=193, Percent_Identity=31.6062176165803, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=224, Percent_Identity=25, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=224, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=224, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007184, Length=238, Percent_Identity=26.890756302521, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221500365, Length=238, Percent_Identity=26.890756302521, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI85724864, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580555, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI85816269, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580553, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574150, Length=234, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007328, Length=234, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582014, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24582012, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161076682, Length=188, Percent_Identity=29.2553191489362, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076684, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581617, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581615, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26561; Mature: 26429

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNMITVKQLTYKRNRKVILDDLNLDLVQGHFIGLLGANGAGKTTLMRLLNGVATTFHG
CCCCEEEHHHHHHHCCCEEEEECCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHEE
TIQIGSSESIVERKQLSSFSESLNGVNPNRTLKQIATYYADMYLDFSEAEFANFLKTFDL
EEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DSHQKLAALSKGNRKKLIAALTLARQTQLYLLDEPFEGIDSMTRKRIISNLIAWKPAAAT
CCHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEE
VIISDHHVSDVANVLDEVVIIKDKHVVAQKNAEELREKTGMSIENYYESFYEGSDQQ
EEEECCCHHHHHHHHHHHEEEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTNMITVKQLTYKRNRKVILDDLNLDLVQGHFIGLLGANGAGKTTLMRLLNGVATTFHG
CCCEEEHHHHHHHCCCEEEEECCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHEE
TIQIGSSESIVERKQLSSFSESLNGVNPNRTLKQIATYYADMYLDFSEAEFANFLKTFDL
EEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DSHQKLAALSKGNRKKLIAALTLARQTQLYLLDEPFEGIDSMTRKRIISNLIAWKPAAAT
CCHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEE
VIISDHHVSDVANVLDEVVIIKDKHVVAQKNAEELREKTGMSIENYYESFYEGSDQQ
EEEECCCHHHHHHHHHHHEEEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]