BacMap

Definition	Lactobacillus casei ATCC 334, complete genome.
Accession	NC_008526
Length	2,895,264

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The map label for this gene is yfnA [H]

Identifier: 116495072

GI number: 116495072

Start: 1587647

End: 1589041

Strand: Direct

Name: yfnA [H]

Synonym: LSEI_1590

Alternate gene names: 116495072

Gene position: 1587647-1589041 (Clockwise)

Preceding gene: 116495071

Following gene: 116495073

Centisome position: 54.84

GC content: 48.24

Gene sequence:

>1395_bases
ATGAATCTTTGGAAACAGATGACCCGAAAACCTGATGTTCAGGCCGCACTCAATGCTGATCATTTACTGACACGCAGTTT
AACAACGCGTGACCTGATCGCGTTAGGTATTGGCGCCGTCATAGGTACGGGAATCTTTATTCTTCCCGGAACAGTAGCGG
CGACTACCAGCGGACCAGCGATCACGATTGCTTTTATTTTGGCTGCCATCGTCTGCTCGCTAGCGGCTATGTGTTATGCC
GAATTCGCATCGGCTCTGCCAGTTGCCGGCTCGGCTTATGCTTACGGCAATCTCGTGTTTGGTCAAGTCTTTGGATGGAT
TATTGGCTGGGCACTTATTTTGGAATATATGCTGGCAGTTGCCGCGGTTTCAACCAGTTTTTCTGCGTATTTCGCTAGTC
TTCTACAAGGCTTTCACATCACCTTGCCAGCAGCCATTGCCGGCCCGTTTTCGCCGAGTCACGGCACTTATGTGAATCTG
ATTGCGGTCATTGTTGTTCTTATCATTGGTGTTATGTTGTCACGCGGTATGCAATCCTCCATGGCGATTAATCGTTTAAT
GGTATTAGTTAAGTTAGTCATTATTGCCATTTTTATTGTCGTTGGCTTTTTTTACGTTCAGCCAGCCAACTGGCATCCAT
ATTTGCCATTTGGTGCAAAAGGCGTACTTGCCGGTGCTGCGATGGTTTTCTTTGCCTATCTCGGCTTTGACGCCGTGTCT
GCTTCAGCACCAGAGGTCAAAAATCCGCAACATACGCTACCACGCGGCATCATCGGCACTTTAGTCATTGCCACCATTTT
GTATGTGTTAGTCGCGATTGTTTTGACCGGCATGGTACCATTCACCAAATTAGATGTGGCCGATCCAGTTGCTTTTGCCT
TGAGCGCCGTGCATCTGCGTAGCGTTGGCGGTATCATTTCGGTAGGCGCCTTGGCTGGCATGTTCACCATGATGGTCACC
ATGATCTACAGCTCATCAAGGTTGATTTATGCGATCGGCCGTGACGGACTGTTACCCCGTTGGTTTGGTCACGTTAAAGG
CCATCTGCCTGAAAATGCGTTGTGGACTGTGGTTTTGATCATTGCGATCATGGGCGGCCTTGTGCCACTCACGCAACTAG
TCAACCTCGTCAATATCGGCACCTTAATTGCTTTTGCCCTCGTCTCAATTGGCATCATCCCCTTGCGCCGACATCAAGCC
TTTAACAACGAAGGTTTCAAGGTTCCTGGGTATCCAGTGACGCCGATTATTTCTTTTCTGTTTTGTCTGCTATTGATGAC
CCAGTTAAGTGTCGAAACTTGGATTATGAGTCTGATCTGGTTTGCCTTCGGACTTGTCATCTACTTCAGCTATGGCATCC
GCCACGGTCATGTTGCCGAAAAAAGAATTGAATGA

Upstream 100 bases:

>100_bases
ACAAGAAGAAATATCTGGAAGAAAAAGAACACGGAGAAGTTTAAGGTTCGCTAGTCGAACCTTTTTCCTTTTTATTCAAT
ACAGAAAGTGAGCTTGATTC

Downstream 100 bases:

>100_bases
ATCTGCTGAATTAAGAAAGGAAAATAAGTCTTGATCAATCCTCAAACTGCAACCTGCTTGGTGGACGGTAAAGTCTATGC
GATTAGCGATGGCCTTTTCT

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNLWKQMTRKPDVQAALNADHLLTRSLTTRDLIALGIGAVIGTGIFILPGTVAATTSGPAITIAFILAAIVCSLAAMCYA
EFASALPVAGSAYAYGNLVFGQVFGWIIGWALILEYMLAVAAVSTSFSAYFASLLQGFHITLPAAIAGPFSPSHGTYVNL
IAVIVVLIIGVMLSRGMQSSMAINRLMVLVKLVIIAIFIVVGFFYVQPANWHPYLPFGAKGVLAGAAMVFFAYLGFDAVS
ASAPEVKNPQHTLPRGIIGTLVIATILYVLVAIVLTGMVPFTKLDVADPVAFALSAVHLRSVGGIISVGALAGMFTMMVT
MIYSSSRLIYAIGRDGLLPRWFGHVKGHLPENALWTVVLIIAIMGGLVPLTQLVNLVNIGTLIAFALVSIGIIPLRRHQA
FNNEGFKVPGYPVTPIISFLFCLLLMTQLSVETWIMSLIWFAFGLVIYFSYGIRHGHVAEKRIE

Sequences:

>Translated_464_residues
MNLWKQMTRKPDVQAALNADHLLTRSLTTRDLIALGIGAVIGTGIFILPGTVAATTSGPAITIAFILAAIVCSLAAMCYA
EFASALPVAGSAYAYGNLVFGQVFGWIIGWALILEYMLAVAAVSTSFSAYFASLLQGFHITLPAAIAGPFSPSHGTYVNL
IAVIVVLIIGVMLSRGMQSSMAINRLMVLVKLVIIAIFIVVGFFYVQPANWHPYLPFGAKGVLAGAAMVFFAYLGFDAVS
ASAPEVKNPQHTLPRGIIGTLVIATILYVLVAIVLTGMVPFTKLDVADPVAFALSAVHLRSVGGIISVGALAGMFTMMVT
MIYSSSRLIYAIGRDGLLPRWFGHVKGHLPENALWTVVLIIAIMGGLVPLTQLVNLVNIGTLIAFALVSIGIIPLRRHQA
FNNEGFKVPGYPVTPIISFLFCLLLMTQLSVETWIMSLIWFAFGLVIYFSYGIRHGHVAEKRIE
>Mature_464_residues
MNLWKQMTRKPDVQAALNADHLLTRSLTTRDLIALGIGAVIGTGIFILPGTVAATTSGPAITIAFILAAIVCSLAAMCYA
EFASALPVAGSAYAYGNLVFGQVFGWIIGWALILEYMLAVAAVSTSFSAYFASLLQGFHITLPAAIAGPFSPSHGTYVNL
IAVIVVLIIGVMLSRGMQSSMAINRLMVLVKLVIIAIFIVVGFFYVQPANWHPYLPFGAKGVLAGAAMVFFAYLGFDAVS
ASAPEVKNPQHTLPRGIIGTLVIATILYVLVAIVLTGMVPFTKLDVADPVAFALSAVHLRSVGGIISVGALAGMFTMMVT
MIYSSSRLIYAIGRDGLLPRWFGHVKGHLPENALWTVVLIIAIMGGLVPLTQLVNLVNIGTLIAFALVSIGIIPLRRHQA
FNNEGFKVPGYPVTPIISFLFCLLLMTQLSVETWIMSLIWFAFGLVIYFSYGIRHGHVAEKRIE

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=392, Percent_Identity=32.6530612244898, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI4507047, Length=436, Percent_Identity=32.3394495412844, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI258645169, Length=426, Percent_Identity=31.6901408450704, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI258614005, Length=427, Percent_Identity=31.1475409836066, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI258614003, Length=427, Percent_Identity=31.1475409836066, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI114326544, Length=421, Percent_Identity=32.3040380047506, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI114326550, Length=421, Percent_Identity=32.3040380047506, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI110347453, Length=406, Percent_Identity=33.743842364532, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI187423910, Length=472, Percent_Identity=23.9406779661017, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI7657591, Length=472, Percent_Identity=23.9406779661017, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI71999149, Length=383, Percent_Identity=25.8485639686684, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33286428, Length=401, Percent_Identity=24.9376558603491, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7657683, Length=366, Percent_Identity=25.6830601092896, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI71979932, Length=415, Percent_Identity=24.0963855421687, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI115648063, Length=390, Percent_Identity=22.3076923076923, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI115648022, Length=390, Percent_Identity=22.3076923076923, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI186910308, Length=469, Percent_Identity=22.6012793176972, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI186910306, Length=469, Percent_Identity=22.6012793176972, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI186910304, Length=469, Percent_Identity=22.6012793176972, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI9790235, Length=330, Percent_Identity=23.9393939393939, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081708, Length=471, Percent_Identity=22.5053078556263, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788480, Length=448, Percent_Identity=21.875, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082250, Length=347, Percent_Identity=27.0893371757925, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87082023, Length=448, Percent_Identity=25.6696428571429, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081869, Length=463, Percent_Identity=23.9740820734341, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786302, Length=422, Percent_Identity=22.7488151658768, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790653, Length=401, Percent_Identity=22.6932668329177, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786694, Length=384, Percent_Identity=25.2604166666667, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367353, Length=409, Percent_Identity=26.6503667481663, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081915, Length=440, Percent_Identity=20.4545454545455, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786602, Length=440, Percent_Identity=22.0454545454545, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994972, Length=357, Percent_Identity=24.0896358543417, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789017, Length=341, Percent_Identity=20.8211143695015, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786789, Length=350, Percent_Identity=20.2857142857143, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=412, Percent_Identity=34.9514563106796, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=35.0490196078431, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI17532491, Length=399, Percent_Identity=34.5864661654135, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71982612, Length=418, Percent_Identity=23.2057416267943, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982608, Length=418, Percent_Identity=23.2057416267943, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=409, Percent_Identity=23.7163814180929, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=409, Percent_Identity=23.7163814180929, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=299, Percent_Identity=23.4113712374582, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537453, Length=390, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17568033, Length=349, Percent_Identity=22.6361031518625, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71995382, Length=334, Percent_Identity=22.7544910179641, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995388, Length=334, Percent_Identity=22.7544910179641, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982623, Length=267, Percent_Identity=22.8464419475655, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=414, Percent_Identity=23.6714975845411, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71993915, Length=360, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319543, Length=364, Percent_Identity=22.5274725274725, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324990, Length=455, Percent_Identity=22.4175824175824, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668806, Length=470, Percent_Identity=32.3404255319149, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI21356285, Length=470, Percent_Identity=32.3404255319149, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24668802, Length=470, Percent_Identity=32.3404255319149, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24667468, Length=437, Percent_Identity=34.0961098398169, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI221512776, Length=427, Percent_Identity=30.2107728337237, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24666159, Length=427, Percent_Identity=30.2107728337237, Blast_Score=221, Evalue=7e-58,
Organism=Drosophila melanogaster, GI281366235, Length=412, Percent_Identity=33.252427184466, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI116007820, Length=412, Percent_Identity=33.252427184466, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI116007818, Length=412, Percent_Identity=33.495145631068, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI85725152, Length=412, Percent_Identity=33.495145631068, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI161077963, Length=410, Percent_Identity=33.6585365853659, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI45550968, Length=366, Percent_Identity=23.4972677595628, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921172, Length=366, Percent_Identity=23.4972677595628, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357367, Length=356, Percent_Identity=21.9101123595506, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221331183, Length=325, Percent_Identity=23.3846153846154, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17647653, Length=325, Percent_Identity=23.3846153846154, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24664379, Length=325, Percent_Identity=23.3846153846154, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24651635, Length=400, Percent_Identity=22.5, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24651633, Length=400, Percent_Identity=22.5, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641993, Length=342, Percent_Identity=25.1461988304094, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24641995, Length=342, Percent_Identity=25.1461988304094, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49717; Mature: 49717

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]