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The map label for this gene is engA

Identifier: 116494866

GI number: 116494866

Start: 1368195

End: 1369502

Strand: Direct

Name: engA

Synonym: LSEI_1380

Alternate gene names: 116494866

Gene position: 1368195-1369502 (Clockwise)

Preceding gene: 116494865

Following gene: 116494867

Centisome position: 47.26

GC content: 46.1

Gene sequence:

>1308_bases
ATGGTCTTACCAACATTAGCAATCGTTGGCCGTCCGAATGTGGGCAAGTCAACCATTTTTAACCGTATTCTCGGTGAGCG
GGTTTCGATTGTGGAAGATACGCCCGGGGTCACGCGTGATCGCATCTATGGCAAGAGTGAATGGCTTGGTAAAGAATTTG
CTGTCATTGACACCGGTGGGATCGACTTAGGCGATGAACCTTTTTTGGCGCAAATTAAGGATCAAGCTGAAATTGCCATC
GATGAAGCCGATGTCATCCTTTTTCTCGCTGATATTGAAAGCGGGGTAACTGATGCAGATGAACGGGTAGCCCAGATTCT
TTATCGGGCTAAAAAGCCGGTCGTACTGGCAGTCAATAAGGTTGATAACCCTGAACGTCGCCAAGATATTTACGATTTTT
ATTCATTAGGTTTTGGCGAACCCTATCCACTTTCTGGGACCCATGGGATTGGCCTTGGTGATGTTTTGGATGCTGTTTTA
GCAGCATTTCCATCCGAAGATAAGTCAGTTGAAGACGATTCGATTAAGTTCAGCCTGATTGGTCGGCCAAATGTCGGTAA
ATCGTCTTTAGTTAACGCCATTCTTGGTGAAAATCGGGTCATCGTGAGTCCAATCGAAGGCACGACCCGCGATGCGATTG
ATACGAAGTTCGAAGCAGTTGACGAAACCTTCACGATGATTGACACGGCTGGGATTCGTAAACGTGGTAAGGTTTACGAG
AACACCGAAAAATACGCGGTCATGCGTGCATTACGAGCGATTGATCGTTCGGATGTTGTTTTGTTTGTCATCAACGCCGA
AGAAGGTATCCGCGAACAGGATAAAAAGGTCGCCGGTTATGCCCACGAGGCCGGTCGTGGCATCATCATCGTCGTCAACA
AGTGGGATACAGTTGAGAAAGATAATCACACGATGAAGGATTTTGAAAACCTGATTCGTCAGGAATTCCAATATCTGGAT
TATGCGCCGATTATTTTTGTTTCTGCCAAGACGAAACAGCGTTTACAGAGCTTGCCAGCCATGATTGTGGCAGTTTCAGA
AAATCAAACTCGGCGAATTCAAAGCAGTGTCCTAAATGATGTCTTAATGGATGCCATTACTGTTACACCGACACCGACAG
TTAACGGAAAACGCTTGCGGATTTATTACATGACCCAAGTTGCTGTCAAACCGCCAACTTTCGTGGTTTTTGTTAATGAT
CCCGACCTGCTGCACTTCTCGTACGAGCGATTCCTGATTAACCAATTGCGACAGGCCTTTGATTTTTCCGGTACACCGAT
TCACATCATCGCACGTAAACGCAAGTAG

Upstream 100 bases:

>100_bases
ATAACAAGTAGTCATCTTGAACCTAAAAAGTTGAGCCTTGGCTCAACTTTTTTTATGGGAAACAAATCCCATGACGCCGT
CACAGAAAGGAGGCCGTTTT

Downstream 100 bases:

>100_bases
TTCGGCGATGGCTGAATATTGTCTTTTCATTTAAAAAAATATGTCAAAAATCGTGATTTTCGATAACCGATCCTTGATCA
GACAGCAAAAAGTTTGGCAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGGIDLGDEPFLAQIKDQAEIAI
DEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNKVDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVL
AAFPSEDKSVEDDSIKFSLIGRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYE
NTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEKDNHTMKDFENLIRQEFQYLD
YAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLNDVLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVND
PDLLHFSYERFLINQLRQAFDFSGTPIHIIARKRK

Sequences:

>Translated_435_residues
MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGGIDLGDEPFLAQIKDQAEIAI
DEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNKVDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVL
AAFPSEDKSVEDDSIKFSLIGRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYE
NTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEKDNHTMKDFENLIRQEFQYLD
YAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLNDVLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVND
PDLLHFSYERFLINQLRQAFDFSGTPIHIIARKRK
>Mature_435_residues
MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGGIDLGDEPFLAQIKDQAEIAI
DEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNKVDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVL
AAFPSEDKSVEDDSIKFSLIGRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYE
NTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEKDNHTMKDFENLIRQEFQYLD
YAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLNDVLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVND
PDLLHFSYERFLINQLRQAFDFSGTPIHIIARKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=38.1263616557734, Blast_Score=321, Evalue=7e-89,
Organism=Escherichia coli, GI1788919, Length=176, Percent_Identity=30.1136363636364, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI2367268, Length=111, Percent_Identity=36.9369369369369, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=212, Percent_Identity=32.0754716981132, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_LACC3 (Q039G4)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806600.1
- ProteinModelPortal:   Q039G4
- SMR:   Q039G4
- STRING:   Q039G4
- GeneID:   4419799
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1380
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q039G4
- ProtClustDB:   PRK00093
- BioCyc:   LCAS321967:LSEI_1380-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48612; Mature: 48612

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGG
CCCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHCCCCHHHCCCEEEEEECCC
IDLGDEPFLAQIKDQAEIAIDEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNK
CCCCCCCHHHHHCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
VDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVLAAFPSEDKSVEDDSIKFSLI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYE
CCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEK
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCHHHCCCEEEEEEECCCCCCC
DNHTMKDFENLIRQEFQYLDYAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLND
CCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
VLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVNDPDLLHFSYERFLINQLRQAF
HHHHHEEECCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
DFSGTPIHIIARKRK
CCCCCEEEEEEECCC
>Mature Secondary Structure
MVLPTLAIVGRPNVGKSTIFNRILGERVSIVEDTPGVTRDRIYGKSEWLGKEFAVIDTGG
CCCCCEEEECCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHCCCCHHHCCCEEEEEECCC
IDLGDEPFLAQIKDQAEIAIDEADVILFLADIESGVTDADERVAQILYRAKKPVVLAVNK
CCCCCCCHHHHHCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEC
VDNPERRQDIYDFYSLGFGEPYPLSGTHGIGLGDVLDAVLAAFPSEDKSVEDDSIKFSLI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GRPNVGKSSLVNAILGENRVIVSPIEGTTRDAIDTKFEAVDETFTMIDTAGIRKRGKVYE
CCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NTEKYAVMRALRAIDRSDVVLFVINAEEGIREQDKKVAGYAHEAGRGIIIVVNKWDTVEK
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCHHHCCCEEEEEEECCCCCCC
DNHTMKDFENLIRQEFQYLDYAPIIFVSAKTKQRLQSLPAMIVAVSENQTRRIQSSVLND
CCCHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHCCCEEEEEECCCHHHHHHHHHHHH
VLMDAITVTPTPTVNGKRLRIYYMTQVAVKPPTFVVFVNDPDLLHFSYERFLINQLRQAF
HHHHHEEECCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
DFSGTPIHIIARKRK
CCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA