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The map label for this gene is ftsW [H]

Identifier: 116494803

GI number: 116494803

Start: 1298538

End: 1299707

Strand: Direct

Name: ftsW [H]

Synonym: LSEI_1314

Alternate gene names: 116494803

Gene position: 1298538-1299707 (Clockwise)

Preceding gene: 116494802

Following gene: 116494804

Centisome position: 44.85

GC content: 46.84

Gene sequence:

>1170_bases
ATGAATAAATTACGGCACGTGGATTACTTCATATTAGTTCCGTACCTCGTTTTATGTGCGATCGGTATTGTCATGGTGTA
CTCTGCCAGCGCTTATTGGGTTCAACGGCAATATGGCGTTGCCGAAACGAAATACTTGATTCAACAGGCACTGTTTGTCC
TGCTCGGTATCGCGACTGTGTTTTTCTTTTATAATATGTCCTTGAAGGTGGTCCACAATCGTTGGGTTCTGTTGACTTTA
ATGGCCGGACTAGTTGTGATGCTGATCTATCTCATTGTGCACGGCCGCGCCGTTAACGGGGCCGCTGCATGGATCACGAT
TGGCGGGTTTCGCTTACAGCCATCAGAATTTGCTAAAATGATTTTGATTTTTTATCTGGCGCACATGCTGACATCGCGCG
AGGATCGCTTTCAACAAGAGGACTTTCGGCTAAGGCAGATGTGGCAGCCATTGTTTGTCGCTGGTATGATCATGCTTCTG
GTTTTTGTCGAACCGGATACCGGTGGATTTGCCATTCTTTTCTTGATTACATTGGTCGTGGTTATGTCCAGCGGGATACC
GATGCGTTACGGTTTTTTGTGGGTCTTGATGTTGATCGCGATCACAGCACTGGGCTACTACATCGTGTCGCATTATCATT
TTCCCGGATTGGAGAAGAATTACGGCTATCAACGATTAGTGGCCGCCATTCATCCGTTTGCTAAAGCGAATACGGTTGGC
AATCAGGTTGTTAACTCCTTGTATGCGATCAATCACGGTGGGCTGTTTGGTGTTGGACTAGGCATGGGCAGCCAAAAGTT
AGGCTATCTACCTGAGCCTTATACTGACTTTATTTTGGCCGTGATTGCCGAGGAACTTGGCTTGGTTGGGACATTTGTCG
TATTGAGTTTGCTGTTTTTCCTGATCATGCGTTTTTATCTGATCGGAATTCGCTCCAAGAACACCTATCACACGTTGATC
GCGTACGGCATTGCCACGATGATGCTGGTGCAAACCGTTTTCAACGTTGGTGCTGTGACTGGGGTTTTGCCAGTTACCGG
GGTGACGCTGCCGTTTATCAGTTACGGCGGTTCGAGTATGATCGTGCTGTCAATGGCGATCGGCATTATGTTAAATATCA
GTTATCATAGTGAACGTACGCAACGAAAGGTAGAGAAGACGCATGCATAA

Upstream 100 bases:

>100_bases
AAAAACAGTTTTTAGTGATTACCGCAGAACACGGCTTGGAGCGTGAAGGCGATATGCTATAATTAGTCCATTAATTGCTT
GAAAGGCCGCGTTTTCATTG

Downstream 100 bases:

>100_bases
AGTTTTAGTCGCTAATCGTGGCGAAATCGCCATTCGGATTTTTCGTGCCTGTGAAGAGCTTGGTCTTAAAACAGTCGGTA
TTTTTGCTAAAGAGGACGCT

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNKLRHVDYFILVPYLVLCAIGIVMVYSASAYWVQRQYGVAETKYLIQQALFVLLGIATVFFFYNMSLKVVHNRWVLLTL
MAGLVVMLIYLIVHGRAVNGAAAWITIGGFRLQPSEFAKMILIFYLAHMLTSREDRFQQEDFRLRQMWQPLFVAGMIMLL
VFVEPDTGGFAILFLITLVVVMSSGIPMRYGFLWVLMLIAITALGYYIVSHYHFPGLEKNYGYQRLVAAIHPFAKANTVG
NQVVNSLYAINHGGLFGVGLGMGSQKLGYLPEPYTDFILAVIAEELGLVGTFVVLSLLFFLIMRFYLIGIRSKNTYHTLI
AYGIATMMLVQTVFNVGAVTGVLPVTGVTLPFISYGGSSMIVLSMAIGIMLNISYHSERTQRKVEKTHA

Sequences:

>Translated_389_residues
MNKLRHVDYFILVPYLVLCAIGIVMVYSASAYWVQRQYGVAETKYLIQQALFVLLGIATVFFFYNMSLKVVHNRWVLLTL
MAGLVVMLIYLIVHGRAVNGAAAWITIGGFRLQPSEFAKMILIFYLAHMLTSREDRFQQEDFRLRQMWQPLFVAGMIMLL
VFVEPDTGGFAILFLITLVVVMSSGIPMRYGFLWVLMLIAITALGYYIVSHYHFPGLEKNYGYQRLVAAIHPFAKANTVG
NQVVNSLYAINHGGLFGVGLGMGSQKLGYLPEPYTDFILAVIAEELGLVGTFVVLSLLFFLIMRFYLIGIRSKNTYHTLI
AYGIATMMLVQTVFNVGAVTGVLPVTGVTLPFISYGGSSMIVLSMAIGIMLNISYHSERTQRKVEKTHA
>Mature_389_residues
MNKLRHVDYFILVPYLVLCAIGIVMVYSASAYWVQRQYGVAETKYLIQQALFVLLGIATVFFFYNMSLKVVHNRWVLLTL
MAGLVVMLIYLIVHGRAVNGAAAWITIGGFRLQPSEFAKMILIFYLAHMLTSREDRFQQEDFRLRQMWQPLFVAGMIMLL
VFVEPDTGGFAILFLITLVVVMSSGIPMRYGFLWVLMLIAITALGYYIVSHYHFPGLEKNYGYQRLVAAIHPFAKANTVG
NQVVNSLYAINHGGLFGVGLGMGSQKLGYLPEPYTDFILAVIAEELGLVGTFVVLSLLFFLIMRFYLIGIRSKNTYHTLI
AYGIATMMLVQTVFNVGAVTGVLPVTGVTLPFISYGGSSMIVLSMAIGIMLNISYHSERTQRKVEKTHA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=375, Percent_Identity=34.1333333333333, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786853, Length=304, Percent_Identity=34.8684210526316, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43616; Mature: 43616

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLRHVDYFILVPYLVLCAIGIVMVYSASAYWVQRQYGVAETKYLIQQALFVLLGIATV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FFFYNMSLKVVHNRWVLLTLMAGLVVMLIYLIVHGRAVNGAAAWITIGGFRLQPSEFAKM
HHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEECHHHHHHH
ILIFYLAHMLTSREDRFQQEDFRLRQMWQPLFVAGMIMLLVFVEPDTGGFAILFLITLVV
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VMSSGIPMRYGFLWVLMLIAITALGYYIVSHYHFPGLEKNYGYQRLVAAIHPFAKANTVG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
NQVVNSLYAINHGGLFGVGLGMGSQKLGYLPEPYTDFILAVIAEELGLVGTFVVLSLLFF
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMRFYLIGIRSKNTYHTLIAYGIATMMLVQTVFNVGAVTGVLPVTGVTLPFISYGGSSM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHH
IVLSMAIGIMLNISYHSERTQRKVEKTHA
HHHHHHHHHHEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKLRHVDYFILVPYLVLCAIGIVMVYSASAYWVQRQYGVAETKYLIQQALFVLLGIATV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FFFYNMSLKVVHNRWVLLTLMAGLVVMLIYLIVHGRAVNGAAAWITIGGFRLQPSEFAKM
HHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEECHHHHHHH
ILIFYLAHMLTSREDRFQQEDFRLRQMWQPLFVAGMIMLLVFVEPDTGGFAILFLITLVV
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VMSSGIPMRYGFLWVLMLIAITALGYYIVSHYHFPGLEKNYGYQRLVAAIHPFAKANTVG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHH
NQVVNSLYAINHGGLFGVGLGMGSQKLGYLPEPYTDFILAVIAEELGLVGTFVVLSLLFF
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIMRFYLIGIRSKNTYHTLIAYGIATMMLVQTVFNVGAVTGVLPVTGVTLPFISYGGSSM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHH
IVLSMAIGIMLNISYHSERTQRKVEKTHA
HHHHHHHHHHEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]