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The map label for this gene is murG

Identifier: 116494763

GI number: 116494763

Start: 1250603

End: 1251694

Strand: Direct

Name: murG

Synonym: LSEI_1272

Alternate gene names: 116494763

Gene position: 1250603-1251694 (Clockwise)

Preceding gene: 116494762

Following gene: 116494764

Centisome position: 43.19

GC content: 47.8

Gene sequence:

>1092_bases
ATGCGGCTGGTGATCTCTGGAGGCGGCACTGGTGGCCACATTTATCCGGCACTGGCGTTGATTGAAGCCTTAAAAGCGGA
AGGAAAACTTGACGATGTGCTTTACGTTGGCACGAAAAGGGGCTTGGAAAGTCGGATTGTACCAGCGACCGGACTTAAGT
TTGCGACGCTCGATTTGCAAGGCTTCAAGCGAAGTCTATCGTTAAGTAATTTCACAACAGTCCGGAAATTTCTTGGTAGC
TTGGGTGAAGCAAAAAAATTGCTACAGGATTTTCAACCTGATATTGTGGTTGGTACCGGTGGCTATGTTTCCGGTGCCAT
CTTATTTGCCGCGACACGATTGCATATTCCAACTGTGATTCATGAATCCAATTCGGTGGCTGGGGTGACGAACAAGTTTC
TGAGTCATTTCGTTGATCGCGTGGCCATCGTTTTTCCTGAAGTTGCTAAGGCTTTTCCAGCCAATAAAGTGGTGGTGACA
GGGAATCCGCGGGCCCAACAAGTTGCTGGTTTGAAGCCAAACGATCGGCTCCGTGATTTCGGCCTTGATCCGCATATTCG
TACTTTGTTAGCCTTTGGTGGTTCTCGTGGGGCGCCACGGATTAATGATGCGGTTGTGGCGGCCTTGCCAATTTGGGCGA
AAGCAGATTTTCAAGTGCTGTTTGCCACTGGCCGGACGCATTACGATCAAATTAAGGCTAAATTGCCTGATTTGCCAGCG
ACAATCAAAGTGGTCCCGTACATTGATGATATGCCATCCATTTTACCCGATATCGGGTTATTGATCAGTCGGGCAGGGGC
GACGACTTTGGCAGAAATCACGGCGCTTGGGATTCCGGCAGTTCTGATTCCCAGTCCCAATGTGACTCATCATCATCAAT
TTTTAAATGCCCAAAGTCTAACGAAACAAGGGGCAGCGATCACAATTACAGAAGATGAATTAGACAATCATTTTCCACGT
CGGGTTGTGACCTTGATGGAAGATGACGAAAAACGTGCCGCAATGGCTAAGGCATCAAAAAAATTAGGTGTCCCAGATGC
AAGTGATCAATTGATCGCAGTGATGACAACGCTACTTTCGAAACGTAGGTGA

Upstream 100 bases:

>100_bases
CGCAAGTTGGGACCAATATCCTAATTTTGAAGTTCGCGGCGATGATTTCATTAAAGCTGTCAATCAATTAAAAGCAACAG
TCGAAAGTGGGGATAAGTAA

Downstream 100 bases:

>100_bases
TAACTTTGGCTTGGCCCCGAAAAAAGAAACCGCAACCTGACCCGCTGACACCGTGGCAGCAATACCAGGCGCGCCAGCAG
CAGACGCCGCGACATGATCG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQGFKRSLSLSNFTTVRKFLGS
LGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVIHESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVT
GNPRAQQVAGLKPNDRLRDFGLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPA
TIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSLTKQGAAITITEDELDNHFPR
RVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLSKRR

Sequences:

>Translated_363_residues
MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQGFKRSLSLSNFTTVRKFLGS
LGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVIHESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVT
GNPRAQQVAGLKPNDRLRDFGLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPA
TIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSLTKQGAAITITEDELDNHFPR
RVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLSKRR
>Mature_363_residues
MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQGFKRSLSLSNFTTVRKFLGS
LGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVIHESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVT
GNPRAQQVAGLKPNDRLRDFGLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPA
TIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSLTKQGAAITITEDELDNHFPR
RVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLSKRR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=359, Percent_Identity=31.1977715877437, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_LACC3 (Q039R7)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806497.1
- ProteinModelPortal:   Q039R7
- STRING:   Q039R7
- GeneID:   4419568
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1272
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q039R7
- ProtClustDB:   PRK00726
- BioCyc:   LCAS321967:LSEI_1272-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38995; Mature: 38995

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQ
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHH
GFKRSLSLSNFTTVRKFLGSLGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVI
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEEE
HESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVTGNPRAQQVAGLKPNDRLRDF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCCHHHHC
GLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPA
CCCHHHHHHHHHCCCCCCCCCCCCEEEEECEEECCCEEEEEEECCCHHHHHHHHCCCCCC
TIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSL
EEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHH
TKQGAAITITEDELDNHFPRRVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLS
HCCCCEEEEEHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KRR
CCC
>Mature Secondary Structure
MRLVISGGGTGGHIYPALALIEALKAEGKLDDVLYVGTKRGLESRIVPATGLKFATLDLQ
CEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHH
GFKRSLSLSNFTTVRKFLGSLGEAKKLLQDFQPDIVVGTGGYVSGAILFAATRLHIPTVI
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCEEE
HESNSVAGVTNKFLSHFVDRVAIVFPEVAKAFPANKVVVTGNPRAQQVAGLKPNDRLRDF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCCHHHHC
GLDPHIRTLLAFGGSRGAPRINDAVVAALPIWAKADFQVLFATGRTHYDQIKAKLPDLPA
CCCHHHHHHHHHCCCCCCCCCCCCEEEEECEEECCCEEEEEEECCCHHHHHHHHCCCCCC
TIKVVPYIDDMPSILPDIGLLISRAGATTLAEITALGIPAVLIPSPNVTHHHQFLNAQSL
EEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHH
TKQGAAITITEDELDNHFPRRVVTLMEDDEKRAAMAKASKKLGVPDASDQLIAVMTTLLS
HCCCCEEEEEHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA