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The map label for this gene is hmrR [H]

Identifier: 116494722

GI number: 116494722

Start: 1205090

End: 1205494

Strand: Direct

Name: hmrR [H]

Synonym: LSEI_1228

Alternate gene names: 116494722

Gene position: 1205090-1205494 (Clockwise)

Preceding gene: 116494715

Following gene: 116494723

Centisome position: 41.62

GC content: 41.23

Gene sequence:

>405_bases
ATGAATATTAGGACATGTGCGCAACAATCCGGTGTTAGCAAAGATACGTTGAGGTTTTATGAAAAGATTGGCTTGATTGT
GCCATCAAGGGGTGAAAATCATTATCGCGATTATACCCCAGATGATGTGGTTAAGTTGCAGATCACGCGAAATTTAAAAG
CGGTTGGGTTGTCTTTAAATGAAATCAGCATGATATTGCGAATGTATGATGCGCCAGTGACAAAGGCTTGTCGCGAAGAT
ACCTTGGCCATTTTGCAAAGTTATCGCGAAGTCTTTAAACGCCGGGCGAAGCTGGATCTTGCCCTTAGCAACATAGCGTT
TGATATGACCACTGCCATTAAAATGCAGGCAGGGGATGATGCAATGATGACATTATTTAAAAAGATAGGGGCAATTAATG
ATTAA

Upstream 100 bases:

>100_bases
ATAATTAGATCTAGGAATAGCTTGTCGATCATTTTCTAGTCCTTGGCCTTGATGTATACTCCAATGTTATTCTGATGACA
CGAAAAAAGGAGATTTTCTT

Downstream 100 bases:

>100_bases
AACAATTGCAGATGGGATTCGTTTTCTGTTAGAAATTGCAACAGTTGTGTTTTTGATCATCGCTGGGTTCAATAGTAGCG
ATCTTGTGGTTAAACTAACT

Product: transcriptional regulator

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MNIRTCAQQSGVSKDTLRFYEKIGLIVPSRGENHYRDYTPDDVVKLQITRNLKAVGLSLNEISMILRMYDAPVTKACRED
TLAILQSYREVFKRRAKLDLALSNIAFDMTTAIKMQAGDDAMMTLFKKIGAIND

Sequences:

>Translated_134_residues
MNIRTCAQQSGVSKDTLRFYEKIGLIVPSRGENHYRDYTPDDVVKLQITRNLKAVGLSLNEISMILRMYDAPVTKACRED
TLAILQSYREVFKRRAKLDLALSNIAFDMTTAIKMQAGDDAMMTLFKKIGAIND
>Mature_134_residues
MNIRTCAQQSGVSKDTLRFYEKIGLIVPSRGENHYRDYTPDDVVKLQITRNLKAVGLSLNEISMILRMYDAPVTKACRED
TLAILQSYREVFKRRAKLDLALSNIAFDMTTAIKMQAGDDAMMTLFKKIGAIND

Specific function: Regulates the transcription of actP. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. In the absence of copper, it negatively regulates the transcription of actP [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15181; Mature: 15181

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRTCAQQSGVSKDTLRFYEKIGLIVPSRGENHYRDYTPDDVVKLQITRNLKAVGLSLN
CCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCHH
EISMILRMYDAPVTKACREDTLAILQSYREVFKRRAKLDLALSNIAFDMTTAIKMQAGDD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH
AMMTLFKKIGAIND
HHHHHHHHHCCCCC
>Mature Secondary Structure
MNIRTCAQQSGVSKDTLRFYEKIGLIVPSRGENHYRDYTPDDVVKLQITRNLKAVGLSLN
CCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCHH
EISMILRMYDAPVTKACREDTLAILQSYREVFKRRAKLDLALSNIAFDMTTAIKMQAGDD
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH
AMMTLFKKIGAIND
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11936079 [H]