Click here to switch to the map view.

The map label for this gene is ywcF [H]

Identifier: 116494669

GI number: 116494669

Start: 1154551

End: 1155756

Strand: Direct

Name: ywcF [H]

Synonym: LSEI_1173

Alternate gene names: 116494669

Gene position: 1154551-1155756 (Clockwise)

Preceding gene: 116494668

Following gene: 116494670

Centisome position: 39.88

GC content: 45.36

Gene sequence:

>1206_bases
GTGGAGTCACACGAAATCAAATCAAACTCAGAGGGTGATCGGATTGATTATGGCATCATCCTGTCAGTCATGTTACTGGC
TTTGATCGGGCTTGTGTCCATCTATCTGGCCACCGCTCATGATACTTCTACGCTACAGAATCCTGTTCGTGCCACGGTTA
TGCAGGCGGCGTGGTATGTGATTGGCGGTATCGGCATTTTTTTCGTTATGCGATTTGATGCGGAGCAGCTTTGGCGCATT
GCCCCTTATTTATACGGGATTGGCATTTTTCTGATGATTGCGGTATTGATTTTTTATGACCGCAACACAGAAGCCAGTAC
AGGTGCGAAAAGCTGGTTTGCCCTTGGCCCGATCAGTTTTCAGCCGTCAGAAGTGATGAAACCTGCCTATATTTTGATGT
TGAGTCGCGTTGTGACCCAACACAATGCTGCTTTTTCACATACCATTCAACACGATTGGCAGTTAATTGGCCGGATGGTT
TTGTGGACATTACCGATAGCAGTCCTCATGAAATTTCAAAATGACTTTGGGACGACACTTGTTTTTCTGGCGATTTTCGC
TGGTGTCACCTTGGTTGCCGGGATTAATTGGCGCATTCTCGTGCCGATTGCACTTGTGGCTGGCATTATCGGGACAGTTG
GCATTCTGTTAGTGACGCAGACATGGGGTCGATCTATTCTTGGTAGTATCGGCTTTAAAACATATCAATTTGCCCGAATT
GATTCGTGGTTAAACCCTTCTGGTAGTACAACTGGCGACAGTTATCAGTTGTGGCAATCGATGAAGGCTATCGGTTCTGG
TCAACTGACTGGGAAAGGGCCGATGCACATTGCAGTGCCTGTCCCAGTCCGAGAATCGGATATGATCTTTTCCGTGATTG
GCGAGGCTTTCGGTTTTGTAGGTGCTGCGGTTTTGATTCTGTTATACTTTATGTTGATCTACCAAATGATTAGGGTCACG
TTTGACACAAAAAATGAGTTTTATGCTTACATCTCGACTGGTGTCATCATGATGATCCTATTCCATGTATTTGAAAACAT
CGGCATGAACATCGGGTTACTACCATTGACGGGGATTCCGCTACCATTTATTTCACAAGGTGGTTCATTCTTGTTGGCTA
ATATGTTATCAGTCGGGATGGTCTTGTCGATGCGCTACCATCATACGAGCTACATGTTTAGTCGCGACACAGAAGATTTT
GAATAG

Upstream 100 bases:

>100_bases
AGGCGACCTTGAGACGACCTGTTGGGTTTTGACCCTTTAGTTTCAAGGCTGTTATGTGCACGTTTCTGCGTCAGTGAACG
TGTTTAAAGGAGGGCAGCCC

Downstream 100 bases:

>100_bases
GGGAGAGCAAAATGGCAACAACTTATTTTTGGCAAGATGAACTGGCTGCCGGGCAAATTCGTCTCGGCTTGACCCAAGAG
GCTCAAGAAACGTTAGGCAA

Product: cell division membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MESHEIKSNSEGDRIDYGIILSVMLLALIGLVSIYLATAHDTSTLQNPVRATVMQAAWYVIGGIGIFFVMRFDAEQLWRI
APYLYGIGIFLMIAVLIFYDRNTEASTGAKSWFALGPISFQPSEVMKPAYILMLSRVVTQHNAAFSHTIQHDWQLIGRMV
LWTLPIAVLMKFQNDFGTTLVFLAIFAGVTLVAGINWRILVPIALVAGIIGTVGILLVTQTWGRSILGSIGFKTYQFARI
DSWLNPSGSTTGDSYQLWQSMKAIGSGQLTGKGPMHIAVPVPVRESDMIFSVIGEAFGFVGAAVLILLYFMLIYQMIRVT
FDTKNEFYAYISTGVIMMILFHVFENIGMNIGLLPLTGIPLPFISQGGSFLLANMLSVGMVLSMRYHHTSYMFSRDTEDF
E

Sequences:

>Translated_401_residues
MESHEIKSNSEGDRIDYGIILSVMLLALIGLVSIYLATAHDTSTLQNPVRATVMQAAWYVIGGIGIFFVMRFDAEQLWRI
APYLYGIGIFLMIAVLIFYDRNTEASTGAKSWFALGPISFQPSEVMKPAYILMLSRVVTQHNAAFSHTIQHDWQLIGRMV
LWTLPIAVLMKFQNDFGTTLVFLAIFAGVTLVAGINWRILVPIALVAGIIGTVGILLVTQTWGRSILGSIGFKTYQFARI
DSWLNPSGSTTGDSYQLWQSMKAIGSGQLTGKGPMHIAVPVPVRESDMIFSVIGEAFGFVGAAVLILLYFMLIYQMIRVT
FDTKNEFYAYISTGVIMMILFHVFENIGMNIGLLPLTGIPLPFISQGGSFLLANMLSVGMVLSMRYHHTSYMFSRDTEDF
E
>Mature_401_residues
MESHEIKSNSEGDRIDYGIILSVMLLALIGLVSIYLATAHDTSTLQNPVRATVMQAAWYVIGGIGIFFVMRFDAEQLWRI
APYLYGIGIFLMIAVLIFYDRNTEASTGAKSWFALGPISFQPSEVMKPAYILMLSRVVTQHNAAFSHTIQHDWQLIGRMV
LWTLPIAVLMKFQNDFGTTLVFLAIFAGVTLVAGINWRILVPIALVAGIIGTVGILLVTQTWGRSILGSIGFKTYQFARI
DSWLNPSGSTTGDSYQLWQSMKAIGSGQLTGKGPMHIAVPVPVRESDMIFSVIGEAFGFVGAAVLILLYFMLIYQMIRVT
FDTKNEFYAYISTGVIMMILFHVFENIGMNIGLLPLTGIPLPFISQGGSFLLANMLSVGMVLSMRYHHTSYMFSRDTEDF
E

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=314, Percent_Identity=33.4394904458599, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786277, Length=314, Percent_Identity=26.1146496815287, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44513; Mature: 44513

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]