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The map label for this gene is ywlC [H]

Identifier: 116494653

GI number: 116494653

Start: 1141763

End: 1142764

Strand: Direct

Name: ywlC [H]

Synonym: LSEI_1157

Alternate gene names: 116494653

Gene position: 1141763-1142764 (Clockwise)

Preceding gene: 116494652

Following gene: 116494654

Centisome position: 39.44

GC content: 50.3

Gene sequence:

>1002_bases
TTGTCAAAACGTTATCACGAATCTGATATTCCGGAAGCTGCGGCTGCGCTGAAGCGTGGTGAGTTGGTGGCCTTTCCCAC
CGAGACTGTTTATGGTCTCGGGGCGGATGCGACCAATGTGACGGCCGTTGGTAAAGTTTATGCTGCTAAAGGGCGACCGT
CTGATAATCCCTTAATCGTAACGGTTGCCGACGCCGATATGGTCGGACAATATGCCACGATTACCCCGCTTGCAGCAAAG
CTGATGCAGGCTTTTTGGCCGGGGCCACTGACAATTATTCTGAATATTTTGCCAGGTCGGCTGTCCATGAAGGTGACTGG
TGGTTTGCAGACAGCTGCCTTCCGAAATCCCGATAACGCGTTAACACGCAAATTGATTGCGACAGCCGGCGTACCCATTG
TCGGTCCATCAGCCAATACTTCGGGCAAGCCGAGTCCAACAACTGCTGACCATGTGTTGCATGATCTTGACGGCAAAATT
GCCGGTGTACTCGATGACGGGCCAACTCAAGTCGGTGTTGAATCAGCAATCATTGATCTCACGGTCACGCCACCAGCTAT
TTTGCGGCCGGGAGCCATTGGACCCGATGAACTTGAACCGTTAATCGGACACGTTGATACGGCAGCACATCATGTTGGCC
AAAACGAAGCACCTAAGGCTCCAGGAATGAAATACAAGCATTATGCACCAGCTGCGCAAGTAGTTGTTGTCGATGATCCA
GCCCAATTTTCGGCAGCGGTTGCTTGGGCTAAACAAACTGGTCAAGTGTTTGGCCTGTTGGCAACTGATGCAATTTTGGC
TCAGTATCCGACGATACCAAGCTATTCACTTGGGAAGAATGTTCAAAGCGCTGCCCACGCTTTATTTGCCGGGTTACGGT
GGTTTGATTTACATCCCGATGTCACGCTGGTCTTAGCACAAGCCTTTTCAAAAACTGAATTAAGTGCTGCTTACATGAAT
CGGCTGTTGAAATCGGCTGGCGATATGCATTTTCAAGGATAG

Upstream 100 bases:

>100_bases
TGAAGGTTAAAAAGCATGGTGTGACCCTTGAACCGATCTGCTACAATTTTTCTACTAAGTTTGAGCTATTTTAAAAAGAA
CATGATTTGGAGGCAACATC

Downstream 100 bases:

>100_bases
TCGCGGCGAATCATAGCGCTAACCGTTTATGAGTGCTGGATTATCGAGGACTCAAGTTTAGCCGTCGTGCTGAATCGTTA
TCTTGGATGATGGCAGCTGT

Product: putative translation factor (SUA5)

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSKRYHESDIPEAAAALKRGELVAFPTETVYGLGADATNVTAVGKVYAAKGRPSDNPLIVTVADADMVGQYATITPLAAK
LMQAFWPGPLTIILNILPGRLSMKVTGGLQTAAFRNPDNALTRKLIATAGVPIVGPSANTSGKPSPTTADHVLHDLDGKI
AGVLDDGPTQVGVESAIIDLTVTPPAILRPGAIGPDELEPLIGHVDTAAHHVGQNEAPKAPGMKYKHYAPAAQVVVVDDP
AQFSAAVAWAKQTGQVFGLLATDAILAQYPTIPSYSLGKNVQSAAHALFAGLRWFDLHPDVTLVLAQAFSKTELSAAYMN
RLLKSAGDMHFQG

Sequences:

>Translated_333_residues
MSKRYHESDIPEAAAALKRGELVAFPTETVYGLGADATNVTAVGKVYAAKGRPSDNPLIVTVADADMVGQYATITPLAAK
LMQAFWPGPLTIILNILPGRLSMKVTGGLQTAAFRNPDNALTRKLIATAGVPIVGPSANTSGKPSPTTADHVLHDLDGKI
AGVLDDGPTQVGVESAIIDLTVTPPAILRPGAIGPDELEPLIGHVDTAAHHVGQNEAPKAPGMKYKHYAPAAQVVVVDDP
AQFSAAVAWAKQTGQVFGLLATDAILAQYPTIPSYSLGKNVQSAAHALFAGLRWFDLHPDVTLVLAQAFSKTELSAAYMN
RLLKSAGDMHFQG
>Mature_332_residues
SKRYHESDIPEAAAALKRGELVAFPTETVYGLGADATNVTAVGKVYAAKGRPSDNPLIVTVADADMVGQYATITPLAAKL
MQAFWPGPLTIILNILPGRLSMKVTGGLQTAAFRNPDNALTRKLIATAGVPIVGPSANTSGKPSPTTADHVLHDLDGKIA
GVLDDGPTQVGVESAIIDLTVTPPAILRPGAIGPDELEPLIGHVDTAAHHVGQNEAPKAPGMKYKHYAPAAQVVVVDDPA
QFSAAVAWAKQTGQVFGLLATDAILAQYPTIPSYSLGKNVQSAAHALFAGLRWFDLHPDVTLVLAQAFSKTELSAAYMNR
LLKSAGDMHFQG

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=155, Percent_Identity=31.6129032258064, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=198, Percent_Identity=31.3131313131313, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=377, Percent_Identity=34.4827586206897, Blast_Score=187, Evalue=2e-48,
Organism=Drosophila melanogaster, GI78707274, Length=179, Percent_Identity=31.2849162011173, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34861; Mature: 34730

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRYHESDIPEAAAALKRGELVAFPTETVYGLGADATNVTAVGKVYAAKGRPSDNPLIV
CCCCCCCCCCHHHHHHHHCCCEEEECCHHHEECCCCCCCCEEHHEEEEECCCCCCCCEEE
TVADADMVGQYATITPLAAKLMQAFWPGPLTIILNILPGRLSMKVTGGLQTAAFRNPDNA
EEECHHHHCCCHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEEECCCCEEEEECCCHHH
LTRKLIATAGVPIVGPSANTSGKPSPTTADHVLHDLDGKIAGVLDDGPTQVGVESAIIDL
HHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE
TVTPPAILRPGAIGPDELEPLIGHVDTAAHHVGQNEAPKAPGMKYKHYAPAAQVVVVDDP
EECCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEECC
AQFSAAVAWAKQTGQVFGLLATDAILAQYPTIPSYSLGKNVQSAAHALFAGLRWFDLHPD
HHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCEEEECCCC
VTLVLAQAFSKTELSAAYMNRLLKSAGDMHFQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKRYHESDIPEAAAALKRGELVAFPTETVYGLGADATNVTAVGKVYAAKGRPSDNPLIV
CCCCCCCCCHHHHHHHHCCCEEEECCHHHEECCCCCCCCEEHHEEEEECCCCCCCCEEE
TVADADMVGQYATITPLAAKLMQAFWPGPLTIILNILPGRLSMKVTGGLQTAAFRNPDNA
EEECHHHHCCCHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEEECCCCEEEEECCCHHH
LTRKLIATAGVPIVGPSANTSGKPSPTTADHVLHDLDGKIAGVLDDGPTQVGVESAIIDL
HHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE
TVTPPAILRPGAIGPDELEPLIGHVDTAAHHVGQNEAPKAPGMKYKHYAPAAQVVVVDDP
EECCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEEECC
AQFSAAVAWAKQTGQVFGLLATDAILAQYPTIPSYSLGKNVQSAAHALFAGLRWFDLHPD
HHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCCEEEECCCC
VTLVLAQAFSKTELSAAYMNRLLKSAGDMHFQG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]