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The map label for this gene is murB [H]

Identifier: 116494507

GI number: 116494507

Start: 987178

End: 988047

Strand: Direct

Name: murB [H]

Synonym: LSEI_1003

Alternate gene names: 116494507

Gene position: 987178-988047 (Clockwise)

Preceding gene: 116494504

Following gene: 116494508

Centisome position: 34.1

GC content: 48.05

Gene sequence:

>870_bases
ATGATGCATGATGAACCTTTGAGTCATTATACGTTTACAAAAACCGGGGGACCGGCTGATTTATTGGCGTTTCCCAAAAA
TGTGGCCGAAGTGCGGGCATTAGTTGATGACGCTCGTGACCAAGGCTTGCCTTTGACGGTGATTGGAAATGCCAGCAATT
TAATTGTCCGGGATGGTGGCATTCGCGGACTGGTGTTGATTTTAACCGAAATGAAAACCATCACGGCCAGTGGCAATCAA
GTGACAGCTGAGGCGGGGGCGCGGTTGATTGATACAACCGAAGCAGCTTACCGAGCAGGTTTGACTGGTCTTGAGTTTGC
TGCTGGCATTCCTGGCAGTGTTGGCGGCGCTGTTTTCATGAACGCGGGCGCTTACGATGGTGAAGTCTGCAACGTCATCA
GCAGTGTTGACGTTTTGACGCGAGAAGGCGAATTAAAGACGTATGATCACCGTGAACTGAAATTCCGTTATCGGCACAGT
GTTGTTCAGGATACAGGTGATGTCGTCTTAAGCGCCACCTTTACGCTCAAAGCGGGTGACAAACCAGTCATTCGAGCAAA
AATGGATGAGTTGAATGCGCGTCGGGCGGCTAAACAACCACTTGAATATCCTTCTTGCGGGTCGGTCTTTAAACGGCCAA
AGGGGCATTTTGTTGGCCCAATGATCCAAAAAGCTGGTCTGCAAGGTCATATTATCGGTGGGGCACAGGTGTCAAAGAAA
CATGCTGGCTTCATCATCAACCTTGGCGATGCAACCGCAACGGATTACCTAGACATGATTCATCTTATACAAAAAACAGT
GAAAGCTAAATTTGATGTTGATCTGGAAACTGAGGTTCGAATTATCGGTGAACCTGGTCAACCAAAATAG

Upstream 100 bases:

>100_bases
CGTGTTCATAACAGCAATTATCTGCTAAAATAGCTTGGTAGTATTTGTGAAAGGACCTGATGTTGTGGTGGATGCGCCGC
GTACGCTTGAAGGAATTACC

Downstream 100 bases:

>100_bases
ACCTTAGGAAGGGGCGACACAATGCATTTAGTCGAAGCCGTTTTGTTCTTGATGGCACTTGTCATCGTCTCAAACGTGCT
CAGTCACTACATTGTGGCTG

Product: UDP-N-acetylmuramate dehydrogenase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MMHDEPLSHYTFTKTGGPADLLAFPKNVAEVRALVDDARDQGLPLTVIGNASNLIVRDGGIRGLVLILTEMKTITASGNQ
VTAEAGARLIDTTEAAYRAGLTGLEFAAGIPGSVGGAVFMNAGAYDGEVCNVISSVDVLTREGELKTYDHRELKFRYRHS
VVQDTGDVVLSATFTLKAGDKPVIRAKMDELNARRAAKQPLEYPSCGSVFKRPKGHFVGPMIQKAGLQGHIIGGAQVSKK
HAGFIINLGDATATDYLDMIHLIQKTVKAKFDVDLETEVRIIGEPGQPK

Sequences:

>Translated_289_residues
MMHDEPLSHYTFTKTGGPADLLAFPKNVAEVRALVDDARDQGLPLTVIGNASNLIVRDGGIRGLVLILTEMKTITASGNQ
VTAEAGARLIDTTEAAYRAGLTGLEFAAGIPGSVGGAVFMNAGAYDGEVCNVISSVDVLTREGELKTYDHRELKFRYRHS
VVQDTGDVVLSATFTLKAGDKPVIRAKMDELNARRAAKQPLEYPSCGSVFKRPKGHFVGPMIQKAGLQGHIIGGAQVSKK
HAGFIINLGDATATDYLDMIHLIQKTVKAKFDVDLETEVRIIGEPGQPK
>Mature_289_residues
MMHDEPLSHYTFTKTGGPADLLAFPKNVAEVRALVDDARDQGLPLTVIGNASNLIVRDGGIRGLVLILTEMKTITASGNQ
VTAEAGARLIDTTEAAYRAGLTGLEFAAGIPGSVGGAVFMNAGAYDGEVCNVISSVDVLTREGELKTYDHRELKFRYRHS
VVQDTGDVVLSATFTLKAGDKPVIRAKMDELNARRAAKQPLEYPSCGSVFKRPKGHFVGPMIQKAGLQGHIIGGAQVSKK
HAGFIINLGDATATDYLDMIHLIQKTVKAKFDVDLETEVRIIGEPGQPK

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 30985; Mature: 30985

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHDEPLSHYTFTKTGGPADLLAFPKNVAEVRALVDDARDQGLPLTVIGNASNLIVRDGG
CCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCC
IRGLVLILTEMKTITASGNQVTAEAGARLIDTTEAAYRAGLTGLEFAAGIPGSVGGAVFM
CCEEEEEEEHHHEEECCCCEEEHHHCCEEEEHHHHHHHHCCCCHHHHCCCCCCCCCEEEE
NAGAYDGEVCNVISSVDVLTREGELKTYDHRELKFRYRHSVVQDTGDVVLSATFTLKAGD
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
KPVIRAKMDELNARRAAKQPLEYPSCGSVFKRPKGHFVGPMIQKAGLQGHIIGGAQVSKK
CCEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCEEEECCCEECCC
HAGFIINLGDATATDYLDMIHLIQKTVKAKFDVDLETEVRIIGEPGQPK
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MMHDEPLSHYTFTKTGGPADLLAFPKNVAEVRALVDDARDQGLPLTVIGNASNLIVRDGG
CCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCC
IRGLVLILTEMKTITASGNQVTAEAGARLIDTTEAAYRAGLTGLEFAAGIPGSVGGAVFM
CCEEEEEEEHHHEEECCCCEEEHHHCCEEEEHHHHHHHHCCCCHHHHCCCCCCCCCEEEE
NAGAYDGEVCNVISSVDVLTREGELKTYDHRELKFRYRHSVVQDTGDVVLSATFTLKAGD
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
KPVIRAKMDELNARRAAKQPLEYPSCGSVFKRPKGHFVGPMIQKAGLQGHIIGGAQVSKK
CCEEEHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHCCCCEEEECCCEECCC
HAGFIINLGDATATDYLDMIHLIQKTVKAKFDVDLETEVRIIGEPGQPK
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA