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The map label for this gene is yvdE [H]

Identifier: 116494485

GI number: 116494485

Start: 963333

End: 964286

Strand: Direct

Name: yvdE [H]

Synonym: LSEI_0979

Alternate gene names: 116494485

Gene position: 963333-964286 (Clockwise)

Preceding gene: 116494483

Following gene: 116494486

Centisome position: 33.27

GC content: 44.44

Gene sequence:

>954_bases
GTGGTCACACTGTCTGATGTCGCGAAAGAAGCCAATGTTTCAAAAATGACCGTGTCCCGTGTCATCAATCATCCTGAGCA
AGTGACGCCTGAGTTAAAACAACTCGTCGAACAAGCAATGGCGATTTTGCATTATCGACCTAACTCTGCAGCGAAGGCTT
TGGCCAATAATCGGACTAACGTTATCAAGTTTTTGATTCTTGAAGATGTGGATACGACCGAACCTTATTACATGACGTTG
CTATTCGGCATTGCCCGAGGACTTGATCGTCAGCAGTATGCTTTGCAATTAGTGACAGATCGCGAGCATCTTGATTTGGA
TCACGCCGATGGGTACATTATTACGGGTGCGCGGTCGACTGATTGTCAATGGATTGATCAGTTAGCGAAACCGGTTGTTT
TATTTGGGGAAAATCGTCATGGTTATGATTTTATTGATACGGACAATAAATTAGGCGAACAGCAAGCAACCGAATATGCG
CTGGCCAAGAATTATCAATCGATTATTTTTCTTGGTATTGATGTGAGAGAACCGTTTGAATATTCGCGTGAAGCAGGGTA
TATCAATACTTTGCAGAGACATCAAAAAGTACCGCAGATTCATCGAATGGGTAATCATAGTCACGAATCGCAACATTTTA
TCAGTGAAAATTGGCGAAAGTTCGCGCGAAATACTGTTTTCATCTGTGCAAGTGATCGCCTCGCGTTAGGAGCGGTCAGA
GCGATTCAACAAAATGGTGGGCGAATTCCAACCGACTTTGGCGTCATCGGATTTGATGGCGTTTTTCTGGATCAAGTCTC
AAATCCAAAATTAACCACCGTGAAACAACCGGTGGTGCAACTTGGTGAACTATTAGCACGGATGCTCTTGCAAAAAATCG
CCCAGTCAGGTGCACAACAAGGTGAACTACTGGTGCCGCCAAAATTAGTGCTTCGCGGGACGATACGCACTTAG

Upstream 100 bases:

>100_bases
GCAACCACTAAGTAAGAACTAATATAAAATAGGGCAAGGAGACTGTCGTTGGTCAATGCCTTTGTCGACGAACTTCAGTT
GAGGAGGGAGGATAGCATTT

Downstream 100 bases:

>100_bases
GTGATTATAGAATTCCGATCTGGCAAAATGAGTTTGTCTACTGATAGGTCGGGGTAACATTCACAGTTATCAAACAGGCC
AACAATTTTCCGCTGGGAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MVTLSDVAKEANVSKMTVSRVINHPEQVTPELKQLVEQAMAILHYRPNSAAKALANNRTNVIKFLILEDVDTTEPYYMTL
LFGIARGLDRQQYALQLVTDREHLDLDHADGYIITGARSTDCQWIDQLAKPVVLFGENRHGYDFIDTDNKLGEQQATEYA
LAKNYQSIIFLGIDVREPFEYSREAGYINTLQRHQKVPQIHRMGNHSHESQHFISENWRKFARNTVFICASDRLALGAVR
AIQQNGGRIPTDFGVIGFDGVFLDQVSNPKLTTVKQPVVQLGELLARMLLQKIAQSGAQQGELLVPPKLVLRGTIRT

Sequences:

>Translated_317_residues
MVTLSDVAKEANVSKMTVSRVINHPEQVTPELKQLVEQAMAILHYRPNSAAKALANNRTNVIKFLILEDVDTTEPYYMTL
LFGIARGLDRQQYALQLVTDREHLDLDHADGYIITGARSTDCQWIDQLAKPVVLFGENRHGYDFIDTDNKLGEQQATEYA
LAKNYQSIIFLGIDVREPFEYSREAGYINTLQRHQKVPQIHRMGNHSHESQHFISENWRKFARNTVFICASDRLALGAVR
AIQQNGGRIPTDFGVIGFDGVFLDQVSNPKLTTVKQPVVQLGELLARMLLQKIAQSGAQQGELLVPPKLVLRGTIRT
>Mature_317_residues
MVTLSDVAKEANVSKMTVSRVINHPEQVTPELKQLVEQAMAILHYRPNSAAKALANNRTNVIKFLILEDVDTTEPYYMTL
LFGIARGLDRQQYALQLVTDREHLDLDHADGYIITGARSTDCQWIDQLAKPVVLFGENRHGYDFIDTDNKLGEQQATEYA
LAKNYQSIIFLGIDVREPFEYSREAGYINTLQRHQKVPQIHRMGNHSHESQHFISENWRKFARNTVFICASDRLALGAVR
AIQQNGGRIPTDFGVIGFDGVFLDQVSNPKLTTVKQPVVQLGELLARMLLQKIAQSGAQQGELLVPPKLVLRGTIRT

Specific function: Repressor Of The Mgl Operon. Binds Galactose And D-Fucose As Inducers. Gals Binds To An Operator DNA Sequence Within Its Own Coding Sequence (Corresponding To Residues 15 To 20). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=337, Percent_Identity=26.7062314540059, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=27.7286135693215, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790369, Length=333, Percent_Identity=25.8258258258258, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790194, Length=338, Percent_Identity=27.5147928994083, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI48994940, Length=328, Percent_Identity=28.3536585365854, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1789068, Length=315, Percent_Identity=27.3015873015873, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786540, Length=370, Percent_Identity=27.027027027027, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789456, Length=338, Percent_Identity=26.3313609467456, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=25.3918495297806, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=24.633431085044, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790715, Length=318, Percent_Identity=26.1006289308176, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35751; Mature: 35751

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLSDVAKEANVSKMTVSRVINHPEQVTPELKQLVEQAMAILHYRPNSAAKALANNRTN
CCCHHHHHHHCCHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
VIKFLILEDVDTTEPYYMTLLFGIARGLDRQQYALQLVTDREHLDLDHADGYIITGARST
EEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCC
DCQWIDQLAKPVVLFGENRHGYDFIDTDNKLGEQQATEYALAKNYQSIIFLGIDVREPFE
CHHHHHHHCCCEEEECCCCCCCCCCCCCCHHCHHHHHHHHHHCCCCEEEEEEECCCCCHH
YSREAGYINTLQRHQKVPQIHRMGNHSHESQHFISENWRKFARNTVFICASDRLALGAVR
HHHCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
AIQQNGGRIPTDFGVIGFDGVFLDQVSNPKLTTVKQPVVQLGELLARMLLQKIAQSGAQQ
HHHHCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GELLVPPKLVLRGTIRT
CCEECCCHHHHCCCCCC
>Mature Secondary Structure
MVTLSDVAKEANVSKMTVSRVINHPEQVTPELKQLVEQAMAILHYRPNSAAKALANNRTN
CCCHHHHHHHCCHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
VIKFLILEDVDTTEPYYMTLLFGIARGLDRQQYALQLVTDREHLDLDHADGYIITGARST
EEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCC
DCQWIDQLAKPVVLFGENRHGYDFIDTDNKLGEQQATEYALAKNYQSIIFLGIDVREPFE
CHHHHHHHCCCEEEECCCCCCCCCCCCCCHHCHHHHHHHHHHCCCCEEEEEEECCCCCHH
YSREAGYINTLQRHQKVPQIHRMGNHSHESQHFISENWRKFARNTVFICASDRLALGAVR
HHHCCCHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHH
AIQQNGGRIPTDFGVIGFDGVFLDQVSNPKLTTVKQPVVQLGELLARMLLQKIAQSGAQQ
HHHHCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GELLVPPKLVLRGTIRT
CCEECCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]