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The map label for this gene is gap [H]

Identifier: 116494473

GI number: 116494473

Start: 948884

End: 949906

Strand: Direct

Name: gap [H]

Synonym: LSEI_0967

Alternate gene names: 116494473

Gene position: 948884-949906 (Clockwise)

Preceding gene: 116494472

Following gene: 116494474

Centisome position: 32.77

GC content: 47.41

Gene sequence:

>1023_bases
ATGACTGTTAAGATTGGTATTAATGGTTTTGGCCGTATCGGTCGTTTGGCATTCCGTCGTATTTACGAATTGGGTGCAAA
GAGCAATGACATCCAGGTTGTTGCAATTAACGATCTGACCAGCCCAACCATGCTGGCTCACTTGCTGAAGTATGATTCAA
CCCACGGTACTTTCCCTGGTGAAGTTAGTGCAACCGATAACGGTATCGTCGTTGACGGTAAAGAATACCGTGTCTACGCA
GAACCGCAAGCCCAGAATATTCCTTGGGTTAAGAACGATGGCGTTGACTATGTTCTTGAATGCACAGGCTTCTACACCTC
TGCTGAAAAGTCACAAGCTCATTTGGACGCAGGCGCAAAGCGTGTTCTGATTTCTGCCCCAGCCGGCAAGATGAAGACCA
TCGTTTACAACGTCAACGATGACACTCTGAATGCAGACGACAAGATTGTTTCTGCTGGTTCTTGCACAACCAACTGCTTG
GCACCAATGGCTTACTTCCTGAACAAGGAATTCGGCATCGAAGTTGGTACCATGACCACCGTTCATGCTTACACCTCAAC
TCAGATGTTGCTTGACGGCCCAGTTCGCGGTGGCAACCTGCGTGCTGCACGTTCCGCTGCTGCTAACACGATTCCTCACA
GCACAGGTGCTGCTAAGGCTATCGGTTTGGTTATCCCAGAATTGAACGGCAAGTTGCAGGGCCACGCACAGCGTGTTTCT
GTTGTTGACGGTTCTTTGACCGAATTGGTTTCCATCTTGAAGACCAAGAACGTTACTGCTGACCAAGTTAACGAAGCTAT
CAAGAAGCACACCGAAAACAACCCTAGCTTTGGCTGGAACGAAGACGAAATCGTATCTTCCGATGTTATCGGTACGACAC
AAGGTTCAATCTTTGATCCTACACAGACCGAAGTTACAACTGCTGGTGACTATCAATTAGTTAAGACGGTTGCTTGGTAC
GATAACGAATATGGCTTTACTTGCCAGATGATCCGTACCTTGCTGAAATTTGCTACTCTCTAA

Upstream 100 bases:

>100_bases
TCGGACGTGGCTGTTAACAGACGTCGGTGCAACTAATTCGATTTTAACTGGGGCAACCCGTTAGAATAAAACCTTATTTC
CTAAAGGAGGAAATTTTAGC

Downstream 100 bases:

>100_bases
TCCGGAGTAACGCTTTTCTAGCCGCAACATCCGAAGCGGAGGGAGCTTACTCCCTCCGCTTTTTTTGGAAATAGGCGATC
AATTCTCAGGATGTTTTAGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTVKIGINGFGRIGRLAFRRIYELGAKSNDIQVVAINDLTSPTMLAHLLKYDSTHGTFPGEVSATDNGIVVDGKEYRVYA
EPQAQNIPWVKNDGVDYVLECTGFYTSAEKSQAHLDAGAKRVLISAPAGKMKTIVYNVNDDTLNADDKIVSAGSCTTNCL
APMAYFLNKEFGIEVGTMTTVHAYTSTQMLLDGPVRGGNLRAARSAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVS
VVDGSLTELVSILKTKNVTADQVNEAIKKHTENNPSFGWNEDEIVSSDVIGTTQGSIFDPTQTEVTTAGDYQLVKTVAWY
DNEYGFTCQMIRTLLKFATL

Sequences:

>Translated_340_residues
MTVKIGINGFGRIGRLAFRRIYELGAKSNDIQVVAINDLTSPTMLAHLLKYDSTHGTFPGEVSATDNGIVVDGKEYRVYA
EPQAQNIPWVKNDGVDYVLECTGFYTSAEKSQAHLDAGAKRVLISAPAGKMKTIVYNVNDDTLNADDKIVSAGSCTTNCL
APMAYFLNKEFGIEVGTMTTVHAYTSTQMLLDGPVRGGNLRAARSAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVS
VVDGSLTELVSILKTKNVTADQVNEAIKKHTENNPSFGWNEDEIVSSDVIGTTQGSIFDPTQTEVTTAGDYQLVKTVAWY
DNEYGFTCQMIRTLLKFATL
>Mature_339_residues
TVKIGINGFGRIGRLAFRRIYELGAKSNDIQVVAINDLTSPTMLAHLLKYDSTHGTFPGEVSATDNGIVVDGKEYRVYAE
PQAQNIPWVKNDGVDYVLECTGFYTSAEKSQAHLDAGAKRVLISAPAGKMKTIVYNVNDDTLNADDKIVSAGSCTTNCLA
PMAYFLNKEFGIEVGTMTTVHAYTSTQMLLDGPVRGGNLRAARSAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVSV
VDGSLTELVSILKTKNVTADQVNEAIKKHTENNPSFGWNEDEIVSSDVIGTTQGSIFDPTQTEVTTAGDYQLVKTVAWYD
NEYGFTCQMIRTLLKFATL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=43.620178041543, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=41.7647058823529, Blast_Score=248, Evalue=4e-66,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=44.9101796407186, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1789295, Length=344, Percent_Identity=40.406976744186, Blast_Score=236, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=345, Percent_Identity=43.4782608695652, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=345, Percent_Identity=43.4782608695652, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17534679, Length=347, Percent_Identity=43.2276657060519, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=347, Percent_Identity=43.2276657060519, Blast_Score=241, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=44.8795180722892, Blast_Score=274, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=44.2771084337349, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=44.047619047619, Blast_Score=270, Evalue=3e-73,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=42.814371257485, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI17933600, Length=338, Percent_Identity=42.8994082840237, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI18110149, Length=338, Percent_Identity=42.8994082840237, Blast_Score=251, Evalue=6e-67,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=42.7299703264095, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=42.7299703264095, Blast_Score=250, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36707; Mature: 36576

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKIGINGFGRIGRLAFRRIYELGAKSNDIQVVAINDLTSPTMLAHLLKYDSTHGTFPG
CEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
EVSATDNGIVVDGKEYRVYAEPQAQNIPWVKNDGVDYVLECTGFYTSAEKSQAHLDAGAK
CCCCCCCCEEECCCEEEEEECCCCCCCCEEECCCCCEEEEECCCCCCCCHHHHHHCCCCC
RVLISAPAGKMKTIVYNVNDDTLNADDKIVSAGSCTTNCLAPMAYFLNKEFGIEVGTMTT
EEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCHHCCEEECCEEE
VHAYTSTQMLLDGPVRGGNLRAARSAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVS
EEEECCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEE
VVDGSLTELVSILKTKNVTADQVNEAIKKHTENNPSFGWNEDEIVSSDVIGTTQGSIFDP
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCCCCCCCEECC
TQTEVTTAGDYQLVKTVAWYDNEYGFTCQMIRTLLKFATL
CCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVKIGINGFGRIGRLAFRRIYELGAKSNDIQVVAINDLTSPTMLAHLLKYDSTHGTFPG
EEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
EVSATDNGIVVDGKEYRVYAEPQAQNIPWVKNDGVDYVLECTGFYTSAEKSQAHLDAGAK
CCCCCCCCEEECCCEEEEEECCCCCCCCEEECCCCCEEEEECCCCCCCCHHHHHHCCCCC
RVLISAPAGKMKTIVYNVNDDTLNADDKIVSAGSCTTNCLAPMAYFLNKEFGIEVGTMTT
EEEEECCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCHHCCEEECCEEE
VHAYTSTQMLLDGPVRGGNLRAARSAAANTIPHSTGAAKAIGLVIPELNGKLQGHAQRVS
EEEECCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEE
VVDGSLTELVSILKTKNVTADQVNEAIKKHTENNPSFGWNEDEIVSSDVIGTTQGSIFDP
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHEECCCCCCCCCCCEECC
TQTEVTTAGDYQLVKTVAWYDNEYGFTCQMIRTLLKFATL
CCCEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579064 [H]