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The map label for this gene is dppE [H]

Identifier: 116493746

GI number: 116493746

Start: 176691

End: 178316

Strand: Direct

Name: dppE [H]

Synonym: LSEI_0175

Alternate gene names: 116493746

Gene position: 176691-178316 (Clockwise)

Preceding gene: 116493745

Following gene: 116493747

Centisome position: 6.1

GC content: 45.2

Gene sequence:

>1626_bases
ATGAAAGTTAAACGATTGGTAGCAGGGGCAATGGTATTTGCCTCAGCTGCACTCTTGGCCGCATGTGGCAGCAAGAGTAG
CAGCAGTAGCTCAGAAACTTTTAATCGAATGGAAAAAGATGTTATTTCCACAATGGATAATGCCCACATTACGGATGTTA
TTAGTGGGCAAGCCGCCGTTGATACTGGTGATGGGTTGTATCGGTATAAAGGCAAGAAATTGGAACCTGCTGTTGCCACT
AAAGTCGTTAAGCCAACGAATAACGGCCTTACTTATACATTCAACTTGCGGAAGACGAAGTGGAGTAACGGCGATCCTGT
TACTGCCAAAGATTTCGTCTTCGCGTGGAAGCGAGCAGCAGATCCGAAAACTAAGTCAGAATATGCTTATCTTTTCTCTG
GCATTAAGAACGCGGATGACATCACTGCTGGTAAGAAGGCTGCTTCAACCCTTGGTGTTAAAGCAGAAGGCGATTATAAG
CTGGTTGTCACGATGGATCGGCCAGTACCGTACTTTAGCACGATGATGGTCAATCCGGTCTTCTTCCCATTGAACCAGAA
GACGGTTGATAAGTATGGCAAGAAGTTCGGTACGCAAAGCAAGTACTTGGTCTTCAATGGCCCGTTCAAGTTGACTAACT
GGAACGGCACTGGCAATTCATGGGATGAAGTGAAGAACACTTCTTACTGGAACGCCAAGCAAGTTAAGCTCGATAAGATT
CACGTTCAAGTGGTTAAGGATTCCAACACAGCTGCTAACTTATTCGCTACGAAGAAACTTGACGATGCGGTTCTGACCGG
TGAAATTGCTAAGCAGCATGCCAAGGACAAGGATTACGTTGGCGATAAGCAAGGTCGGACCACATACTTGGATATGAACG
AAGAAAAGGTACCTGACTTCAAGAATCTGAAGTTGCGTCAAGCTGTCGCGATGGCTATTAATCGTGATGAGTTTGCGAAT
AAGGTTATTGGCGATGGTTCTTTCGGAATCTCAACGATTACACCAGAAAACTCTGGCAGTAATCCAAAGACTGGCGAAGA
CTTCTCTAAGGAAGCTGCTAAGGAATCTAAGACCGTTCAGACATACGATCTTAAGAAAGCTAAGCAACTTTGGGCTGAAG
GTCTGAAGGAAGCCGGTAAGTCTGGTGAAGATGTGACCCTGACGACCGATGACACAGACGTTGCTAAGAAGTCTGCTGAA
TATCTGCAATCTGCTTTGGAACAATTGCCAGGCATGAAGGTTTCCATCTCTTCTGTTCCATTCAAGACCCGGATCCAACG
GTCATTAGATGGCAGTGCTCAGTTCATTCTCTCCGGCTGGCAAGGTGACTTCCCAGATCCAATTTCCTTCTTGGACCTTT
ACACGACTGGCAACACTTACAACTTTAGTCACTGGTCCAATAAACAATATGATGATTTGATTAAGGCTTCTAAGGGAACG
GATGCTAACAGCGAAACCAAGCGATATGATGATCTTCTGAAGGCACAGGAACTGCTTTCTAAGGAATCACCTGTTGCAAC
GCTTTATCAAACTGTTCAAGGCCATTTGCGCAATCCTAAGCTGAAAGGTGCTACTTTCAGCCCAGCCAACATGTATAACT
TTGTTGGGGCTTATATGGCTAAGTAA

Upstream 100 bases:

>100_bases
CTAAAAAGGCCACGAAAACAAGTAATATCTGCAAATTTTCTCTTTACTTTCTTCATACTCTAATGTATTCTCAACGTAAT
ATCATTTTGAGGGTGAGTAA

Downstream 100 bases:

>100_bases
TATTATCAAAATCAAAAAACATCTCCATTTTGTTCAGTGCAAGGTAAGTTGACTGGCGATGGGGATGTTTTTTTGTTCTG
AATAATGCTGTGCAGACAGA

Product: ABC-type oligopeptide transport system, periplasmic component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MKVKRLVAGAMVFASAALLAACGSKSSSSSSETFNRMEKDVISTMDNAHITDVISGQAAVDTGDGLYRYKGKKLEPAVAT
KVVKPTNNGLTYTFNLRKTKWSNGDPVTAKDFVFAWKRAADPKTKSEYAYLFSGIKNADDITAGKKAASTLGVKAEGDYK
LVVTMDRPVPYFSTMMVNPVFFPLNQKTVDKYGKKFGTQSKYLVFNGPFKLTNWNGTGNSWDEVKNTSYWNAKQVKLDKI
HVQVVKDSNTAANLFATKKLDDAVLTGEIAKQHAKDKDYVGDKQGRTTYLDMNEEKVPDFKNLKLRQAVAMAINRDEFAN
KVIGDGSFGISTITPENSGSNPKTGEDFSKEAAKESKTVQTYDLKKAKQLWAEGLKEAGKSGEDVTLTTDDTDVAKKSAE
YLQSALEQLPGMKVSISSVPFKTRIQRSLDGSAQFILSGWQGDFPDPISFLDLYTTGNTYNFSHWSNKQYDDLIKASKGT
DANSETKRYDDLLKAQELLSKESPVATLYQTVQGHLRNPKLKGATFSPANMYNFVGAYMAK

Sequences:

>Translated_541_residues
MKVKRLVAGAMVFASAALLAACGSKSSSSSSETFNRMEKDVISTMDNAHITDVISGQAAVDTGDGLYRYKGKKLEPAVAT
KVVKPTNNGLTYTFNLRKTKWSNGDPVTAKDFVFAWKRAADPKTKSEYAYLFSGIKNADDITAGKKAASTLGVKAEGDYK
LVVTMDRPVPYFSTMMVNPVFFPLNQKTVDKYGKKFGTQSKYLVFNGPFKLTNWNGTGNSWDEVKNTSYWNAKQVKLDKI
HVQVVKDSNTAANLFATKKLDDAVLTGEIAKQHAKDKDYVGDKQGRTTYLDMNEEKVPDFKNLKLRQAVAMAINRDEFAN
KVIGDGSFGISTITPENSGSNPKTGEDFSKEAAKESKTVQTYDLKKAKQLWAEGLKEAGKSGEDVTLTTDDTDVAKKSAE
YLQSALEQLPGMKVSISSVPFKTRIQRSLDGSAQFILSGWQGDFPDPISFLDLYTTGNTYNFSHWSNKQYDDLIKASKGT
DANSETKRYDDLLKAQELLSKESPVATLYQTVQGHLRNPKLKGATFSPANMYNFVGAYMAK
>Mature_541_residues
MKVKRLVAGAMVFASAALLAACGSKSSSSSSETFNRMEKDVISTMDNAHITDVISGQAAVDTGDGLYRYKGKKLEPAVAT
KVVKPTNNGLTYTFNLRKTKWSNGDPVTAKDFVFAWKRAADPKTKSEYAYLFSGIKNADDITAGKKAASTLGVKAEGDYK
LVVTMDRPVPYFSTMMVNPVFFPLNQKTVDKYGKKFGTQSKYLVFNGPFKLTNWNGTGNSWDEVKNTSYWNAKQVKLDKI
HVQVVKDSNTAANLFATKKLDDAVLTGEIAKQHAKDKDYVGDKQGRTTYLDMNEEKVPDFKNLKLRQAVAMAINRDEFAN
KVIGDGSFGISTITPENSGSNPKTGEDFSKEAAKESKTVQTYDLKKAKQLWAEGLKEAGKSGEDVTLTTDDTDVAKKSAE
YLQSALEQLPGMKVSISSVPFKTRIQRSLDGSAQFILSGWQGDFPDPISFLDLYTTGNTYNFSHWSNKQYDDLIKASKGT
DANSETKRYDDLLKAQELLSKESPVATLYQTVQGHLRNPKLKGATFSPANMYNFVGAYMAK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=537, Percent_Identity=28.4916201117318, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1787495, Length=531, Percent_Identity=28.6252354048964, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI87081878, Length=533, Percent_Identity=28.3302063789869, Blast_Score=172, Evalue=7e-44,
Organism=Escherichia coli, GI1787052, Length=547, Percent_Identity=27.0566727605119, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1789966, Length=483, Percent_Identity=24.4306418219462, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787551, Length=494, Percent_Identity=22.8744939271255, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59644; Mature: 59644

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKRLVAGAMVFASAALLAACGSKSSSSSSETFNRMEKDVISTMDNAHITDVISGQAAV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEE
DTGDGLYRYKGKKLEPAVATKVVKPTNNGLTYTFNLRKTKWSNGDPVTAKDFVFAWKRAA
ECCCCEEEECCCCCCHHHHHEEECCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHCC
DPKTKSEYAYLFSGIKNADDITAGKKAASTLGVKAEGDYKLVVTMDRPVPYFSTMMVNPV
CCCCHHHHHHHHHCCCCCCHHHCCHHHHHHCCEEECCCEEEEEEECCCCCHHHHHHCCCE
FFPLNQKTVDKYGKKFGTQSKYLVFNGPFKLTNWNGTGNSWDEVKNTSYWNAKQVKLDKI
EECCCHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCHHHHCCCCCCCCCEEEEEEE
HVQVVKDSNTAANLFATKKLDDAVLTGEIAKQHAKDKDYVGDKQGRTTYLDMNEEKVPDF
EEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHCCCH
KNLKLRQAVAMAINRDEFANKVIGDGSFGISTITPENSGSNPKTGEDFSKEAAKESKTVQ
HCHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCEE
TYDLKKAKQLWAEGLKEAGKSGEDVTLTTDDTDVAKKSAEYLQSALEQLPGMKVSISSVP
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCC
FKTRIQRSLDGSAQFILSGWQGDFPDPISFLDLYTTGNTYNFSHWSNKQYDDLIKASKGT
HHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCC
DANSETKRYDDLLKAQELLSKESPVATLYQTVQGHLRNPKLKGATFSPANMYNFVGAYMA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MKVKRLVAGAMVFASAALLAACGSKSSSSSSETFNRMEKDVISTMDNAHITDVISGQAAV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEE
DTGDGLYRYKGKKLEPAVATKVVKPTNNGLTYTFNLRKTKWSNGDPVTAKDFVFAWKRAA
ECCCCEEEECCCCCCHHHHHEEECCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHCC
DPKTKSEYAYLFSGIKNADDITAGKKAASTLGVKAEGDYKLVVTMDRPVPYFSTMMVNPV
CCCCHHHHHHHHHCCCCCCHHHCCHHHHHHCCEEECCCEEEEEEECCCCCHHHHHHCCCE
FFPLNQKTVDKYGKKFGTQSKYLVFNGPFKLTNWNGTGNSWDEVKNTSYWNAKQVKLDKI
EECCCHHHHHHHHHHHCCCCCEEEEECCEEEECCCCCCCCHHHHCCCCCCCCCEEEEEEE
HVQVVKDSNTAANLFATKKLDDAVLTGEIAKQHAKDKDYVGDKQGRTTYLDMNEEKVPDF
EEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHCCCH
KNLKLRQAVAMAINRDEFANKVIGDGSFGISTITPENSGSNPKTGEDFSKEAAKESKTVQ
HCHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCEE
TYDLKKAKQLWAEGLKEAGKSGEDVTLTTDDTDVAKKSAEYLQSALEQLPGMKVSISSVP
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEECCCC
FKTRIQRSLDGSAQFILSGWQGDFPDPISFLDLYTTGNTYNFSHWSNKQYDDLIKASKGT
HHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHCCCC
DANSETKRYDDLLKAQELLSKESPVATLYQTVQGHLRNPKLKGATFSPANMYNFVGAYMA
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]