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The map label for this gene is nrdD [H]

Identifier: 116493703

GI number: 116493703

Start: 129468

End: 131651

Strand: Direct

Name: nrdD [H]

Synonym: LSEI_0131

Alternate gene names: 116493703

Gene position: 129468-131651 (Clockwise)

Preceding gene: 116493702

Following gene: 116493705

Centisome position: 4.47

GC content: 48.35

Gene sequence:

>2184_bases
ATGATCGAATTTTATACACAAATCAAGAAACGAGACGGGCGCATTGTTAATTTTGATGCATCCAAGATCAGCACTGCAAT
CACGAAGGCGGCAGAAAGTGTGGCAAAACTGGCACCGAGTGACGTGCTGACGATCGATCACTTGACGGATACGGTCACGG
CTAAGATTCGCGATCGCTACCACGATGATGTGGAAATCGCGGAGATCCAAACAGTGGTTGAGCAGACCTTGATCGCTGCA
GAAAAGTATAACTGGGCTGAAGCGTATACTGAGTATCGCTTGAAGCGTGATTTAGCCCGCAAACAGAAGCAAGATGTTAA
TTATAACGTCTCGCGCTTAGTGAATCGCGACGAAAGCGTTGTTAACGAAAATGCCAATAAGGACAGCCGGGTCTTTTCAA
CCCAGCGGGATCTAACTGCAGGGGCAGTGGCCAAGGCAATCGGCCTGAAAATGCTGCCGCCTGCTGTTGCCAACGCGCAT
TTACGTGGCGATATTCATTGGCATGATCTTGACTACACCCCGTTTATGGCCGAAACCAACTGTTGTCTGATTGATTTTGA
CTACATGTTGAACCATGGCTTCAGCATTGGCAATGCCGAAGTTGAACCGGCCCATTCGATTCAAGTTGCTGTGACGCAAA
TGACCCAGATCATCGCTAATGTGGCTTCCAGTCAATACGGCGGCTGCTCCAGCGATCGAACAGATCAGGTCTTGGCGCCA
TTCGCCGAGAAAAACTATCAAAAACATTTGCGTGAATTCGGCAGTGTGATTGATGATCCGGCTAAGCTGGAAGCACTGGC
TGTGAAGCAGACTAAGAAGGATATTTATGATGCCTTGCAAACTTTGGAGTATCAGGTGAACACCCTTTATTCCACCCAAG
GCCAGACGCCATTTGTCACAGTCGGCTTCGGTTTGGGGACCAGTTGGATTGAACGCGAGATCCAAAAAGACATCCTGAAA
ATCCGAATTCTAGGTCTGGGTAAAGAACGGCGGACAGCCATCTTCCCGAAATTGGTCTTTACTTTGAAACGCGGTTTGAA
CCTGAAACCAGAAGATCCAAACTATGATATCAAACAATTGGCGATCGAATGTGCCACCAAACGGATGTATCCTGATGTCG
TTTCCTATGACACCATCAAACGATTGACCGGTTCCTTCAAAGCACCAATGGGCTGCCGTAGCTTCCTGCAGGGTTGGACT
GATCCCAAGACAGGCAAAGAAGTGAACGCTGGGCGGATGAATCTTGGTGTTATCACCGTCAACTTGCCGCGGATTGCAAT
GGAAGCCAATGGCGACAAGGCGAAATTCTGGAAGATTTTTGAAGAACGGATGCGCATCTGTAAGGAAGGCCTGCTCTATA
AGGTTGAACGCACCAAACAAGCAACGCCAGAAAGCGCACCGATCCTCTACAAGTATGGGGCCTTTGGTCACAAGCTGGCT
GACACCGACAGCATTGACGATCTTTTCAAAAATGGGCGGGCAACGGTTTCACTAGGCTATATTGGTTTATATGAAGTCGG
TACTGTTTTCTACGGCTCTGCATGGGAAAAGAATCCCGATGCCAAGGCATTCTCAGTTTCAATCGTGAAGGCTCTGGACG
ATCACTGCAAGGCTTGGGAAAAACAATATGGCTACCACTTCTCGGTTTATGGCACGCCAAGCGAATCGCTAACCGATACC
TTCTGCCGAGCAGATACGAAGAAATTCGGTATCGTGAAGGACATTACGGACAAGGAATACTATACCAACAGTTTCCACTA
CGATGTGCGCAAATCACCAACTCCATTTGAGAAACTTGATTTTGAAAAGGATTATCCGCAATACAGTGCCGGTGGCTTCA
TCCATTATTGTGAATACCCGAACCTGAAGCAGAACCCAAAGGCACTGGAAGCCGTTTGGGACTATGCGTATGACAAGATC
GGCTATCTCGGCACCAACACGCCAATCGATCAATGCTTCAAGTGCGGGTTCAAAGGTGAGTTCACCGCAACGGCCAAAGG
CTATCAATGCCCAGAATGCGGTAACCATGATCCAGCCACTTGCGATGTCGTCAAGCGTCTTTGTGGCTACCTCGGTAACC
CGAACAAGCGGCCAATGGTTCACGGTCGTCAGGAAGAAATTATTCACCGGAAGAAACATATCACGTTTAGCCTGAATCAA
GTGGCTAATCGGCGAGACAAGTAA

Upstream 100 bases:

>100_bases
CCACAAAATTTAGTGGATAACCCGTTACTTTTCCTGCTGAGTCTTGTATACTAGATACATTGTTACAAGCACTTCAAGTT
AACGTAATGGGGGATTAGCC

Downstream 100 bases:

>100_bases
GCCTTAGCAAATGCTCAGGTTGGGATATCGCGTAACGAAAAAAGAATCGTCCTTCGTGGGCGATTCTTTTTTCGTGGCTT
TGTATCATGAACCTTCCTCG

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MIEFYTQIKKRDGRIVNFDASKISTAITKAAESVAKLAPSDVLTIDHLTDTVTAKIRDRYHDDVEIAEIQTVVEQTLIAA
EKYNWAEAYTEYRLKRDLARKQKQDVNYNVSRLVNRDESVVNENANKDSRVFSTQRDLTAGAVAKAIGLKMLPPAVANAH
LRGDIHWHDLDYTPFMAETNCCLIDFDYMLNHGFSIGNAEVEPAHSIQVAVTQMTQIIANVASSQYGGCSSDRTDQVLAP
FAEKNYQKHLREFGSVIDDPAKLEALAVKQTKKDIYDALQTLEYQVNTLYSTQGQTPFVTVGFGLGTSWIEREIQKDILK
IRILGLGKERRTAIFPKLVFTLKRGLNLKPEDPNYDIKQLAIECATKRMYPDVVSYDTIKRLTGSFKAPMGCRSFLQGWT
DPKTGKEVNAGRMNLGVITVNLPRIAMEANGDKAKFWKIFEERMRICKEGLLYKVERTKQATPESAPILYKYGAFGHKLA
DTDSIDDLFKNGRATVSLGYIGLYEVGTVFYGSAWEKNPDAKAFSVSIVKALDDHCKAWEKQYGYHFSVYGTPSESLTDT
FCRADTKKFGIVKDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPQYSAGGFIHYCEYPNLKQNPKALEAVWDYAYDKI
GYLGTNTPIDQCFKCGFKGEFTATAKGYQCPECGNHDPATCDVVKRLCGYLGNPNKRPMVHGRQEEIIHRKKHITFSLNQ
VANRRDK

Sequences:

>Translated_727_residues
MIEFYTQIKKRDGRIVNFDASKISTAITKAAESVAKLAPSDVLTIDHLTDTVTAKIRDRYHDDVEIAEIQTVVEQTLIAA
EKYNWAEAYTEYRLKRDLARKQKQDVNYNVSRLVNRDESVVNENANKDSRVFSTQRDLTAGAVAKAIGLKMLPPAVANAH
LRGDIHWHDLDYTPFMAETNCCLIDFDYMLNHGFSIGNAEVEPAHSIQVAVTQMTQIIANVASSQYGGCSSDRTDQVLAP
FAEKNYQKHLREFGSVIDDPAKLEALAVKQTKKDIYDALQTLEYQVNTLYSTQGQTPFVTVGFGLGTSWIEREIQKDILK
IRILGLGKERRTAIFPKLVFTLKRGLNLKPEDPNYDIKQLAIECATKRMYPDVVSYDTIKRLTGSFKAPMGCRSFLQGWT
DPKTGKEVNAGRMNLGVITVNLPRIAMEANGDKAKFWKIFEERMRICKEGLLYKVERTKQATPESAPILYKYGAFGHKLA
DTDSIDDLFKNGRATVSLGYIGLYEVGTVFYGSAWEKNPDAKAFSVSIVKALDDHCKAWEKQYGYHFSVYGTPSESLTDT
FCRADTKKFGIVKDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPQYSAGGFIHYCEYPNLKQNPKALEAVWDYAYDKI
GYLGTNTPIDQCFKCGFKGEFTATAKGYQCPECGNHDPATCDVVKRLCGYLGNPNKRPMVHGRQEEIIHRKKHITFSLNQ
VANRRDK
>Mature_727_residues
MIEFYTQIKKRDGRIVNFDASKISTAITKAAESVAKLAPSDVLTIDHLTDTVTAKIRDRYHDDVEIAEIQTVVEQTLIAA
EKYNWAEAYTEYRLKRDLARKQKQDVNYNVSRLVNRDESVVNENANKDSRVFSTQRDLTAGAVAKAIGLKMLPPAVANAH
LRGDIHWHDLDYTPFMAETNCCLIDFDYMLNHGFSIGNAEVEPAHSIQVAVTQMTQIIANVASSQYGGCSSDRTDQVLAP
FAEKNYQKHLREFGSVIDDPAKLEALAVKQTKKDIYDALQTLEYQVNTLYSTQGQTPFVTVGFGLGTSWIEREIQKDILK
IRILGLGKERRTAIFPKLVFTLKRGLNLKPEDPNYDIKQLAIECATKRMYPDVVSYDTIKRLTGSFKAPMGCRSFLQGWT
DPKTGKEVNAGRMNLGVITVNLPRIAMEANGDKAKFWKIFEERMRICKEGLLYKVERTKQATPESAPILYKYGAFGHKLA
DTDSIDDLFKNGRATVSLGYIGLYEVGTVFYGSAWEKNPDAKAFSVSIVKALDDHCKAWEKQYGYHFSVYGTPSESLTDT
FCRADTKKFGIVKDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPQYSAGGFIHYCEYPNLKQNPKALEAVWDYAYDKI
GYLGTNTPIDQCFKCGFKGEFTATAKGYQCPECGNHDPATCDVVKRLCGYLGNPNKRPMVHGRQEEIIHRKKHITFSLNQ
VANRRDK

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=711, Percent_Identity=50.492264416315, Blast_Score=724, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 82334; Mature: 82334

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS51161 ATP_CONE ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFYTQIKKRDGRIVNFDASKISTAITKAAESVAKLAPSDVLTIDHLTDTVTAKIRDRY
CCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHC
HDDVEIAEIQTVVEQTLIAAEKYNWAEAYTEYRLKRDLARKQKQDVNYNVSRLVNRDESV
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHH
VNENANKDSRVFSTQRDLTAGAVAKAIGLKMLPPAVANAHLRGDIHWHDLDYTPFMAETN
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEECCEEEECCCCCCCEECCC
CCLIDFDYMLNHGFSIGNAEVEPAHSIQVAVTQMTQIIANVASSQYGGCSSDRTDQVLAP
EEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FAEKNYQKHLREFGSVIDDPAKLEALAVKQTKKDIYDALQTLEYQVNTLYSTQGQTPFVT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEE
VGFGLGTSWIEREIQKDILKIRILGLGKERRTAIFPKLVFTLKRGLNLKPEDPNYDIKQL
EECCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AIECATKRMYPDVVSYDTIKRLTGSFKAPMGCRSFLQGWTDPKTGKEVNAGRMNLGVITV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEE
NLPRIAMEANGDKAKFWKIFEERMRICKEGLLYKVERTKQATPESAPILYKYGAFGHKLA
ECCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCCEEEEECCCCCCCC
DTDSIDDLFKNGRATVSLGYIGLYEVGTVFYGSAWEKNPDAKAFSVSIVKALDDHCKAWE
CCCCHHHHHHCCCCEEEECCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KQYGYHFSVYGTPSESLTDTFCRADTKKFGIVKDITDKEYYTNSFHYDVRKSPTPFEKLD
HHCCEEEEEECCCCHHHHHHHHHCCCHHCCCEECCCCCHHCCCCEEEECCCCCCCHHHCC
FEKDYPQYSAGGFIHYCEYPNLKQNPKALEAVWDYAYDKIGYLGTNTPIDQCFKCGFKGE
CCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
FTATAKGYQCPECGNHDPATCDVVKRLCGYLGNPNKRPMVHGRQEEIIHRKKHITFSLNQ
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEHHH
VANRRDK
HHCCCCC
>Mature Secondary Structure
MIEFYTQIKKRDGRIVNFDASKISTAITKAAESVAKLAPSDVLTIDHLTDTVTAKIRDRY
CCCHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHC
HDDVEIAEIQTVVEQTLIAAEKYNWAEAYTEYRLKRDLARKQKQDVNYNVSRLVNRDESV
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHH
VNENANKDSRVFSTQRDLTAGAVAKAIGLKMLPPAVANAHLRGDIHWHDLDYTPFMAETN
HCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEECCEEEECCCCCCCEECCC
CCLIDFDYMLNHGFSIGNAEVEPAHSIQVAVTQMTQIIANVASSQYGGCSSDRTDQVLAP
EEEEEEHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
FAEKNYQKHLREFGSVIDDPAKLEALAVKQTKKDIYDALQTLEYQVNTLYSTQGQTPFVT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEE
VGFGLGTSWIEREIQKDILKIRILGLGKERRTAIFPKLVFTLKRGLNLKPEDPNYDIKQL
EECCCCHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
AIECATKRMYPDVVSYDTIKRLTGSFKAPMGCRSFLQGWTDPKTGKEVNAGRMNLGVITV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEE
NLPRIAMEANGDKAKFWKIFEERMRICKEGLLYKVERTKQATPESAPILYKYGAFGHKLA
ECCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCCEEEEECCCCCCCC
DTDSIDDLFKNGRATVSLGYIGLYEVGTVFYGSAWEKNPDAKAFSVSIVKALDDHCKAWE
CCCCHHHHHHCCCCEEEECCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KQYGYHFSVYGTPSESLTDTFCRADTKKFGIVKDITDKEYYTNSFHYDVRKSPTPFEKLD
HHCCEEEEEECCCCHHHHHHHHHCCCHHCCCEECCCCCHHCCCCEEEECCCCCCCHHHCC
FEKDYPQYSAGGFIHYCEYPNLKQNPKALEAVWDYAYDKIGYLGTNTPIDQCFKCGFKGE
CCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
FTATAKGYQCPECGNHDPATCDVVKRLCGYLGNPNKRPMVHGRQEEIIHRKKHITFSLNQ
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCEEEHHH
VANRRDK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]