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The map label for this gene is treR [H]

Identifier: 116493532

GI number: 116493532

Start: 1784429

End: 1785151

Strand: Direct

Name: treR [H]

Synonym: PEPE_1805

Alternate gene names: 116493532

Gene position: 1784429-1785151 (Clockwise)

Preceding gene: 116493519

Following gene: 116493533

Centisome position: 97.38

GC content: 35.41

Gene sequence:

>723_bases
ATGGAAAGTAAATACGATTTAATAAAACAAGATATTGCCAATAAAATTATTCATGGTATCTATCCTGCCGGTTCTTATTT
ACCTAGTGAAAACGAACTTTGCGACCTATATGGAACTTCACGTGAAACTGTTCGAAAAGCTTTGGTGCTCTTGCTAGAAC
TGGGCTACATTCAAAAAATTAAAGGCAAAGGATCAATCGTCCTCGATGTTTCTAGATTTGTTTTCCCAGTTTCCGGTATC
AAATCGTTCAAAGAGCTCAATCAATCACAAAATATGCATTCAACTACAAAAGTACTTACATTAGAGCCTCGTTTGGTGCC
TACCAAGGATTTTGGTCTCGATCAAAATAGTGAGTTAGAAGCTACTTATATTGAACGTTTAAGAACCATTAATGATGAAC
CCATCATTATTGATATAGATTACGTACTCTCAAAGGTAGTTAATGATATTCCAAAAATGGCTGCTGAAAATTCTCTGTAT
GAATATTTCGAAGACCAACTTGGACTGGATATTAGCTATGCTACTAAAACCATCACGGTCGAAGAGCCTACTGAACGCCA
ACGTCAATTATTAAAAATTCCACCACACAAAGACGTCGTAGTAATTCGAAGTATGACTTATCTCAATGACACCACGTTGT
TCCAATTTACCGAATCTATTCATCGAGCTGATAAATTTAGTTTTGTTGATTTTGCTAGAAGACAAAAATTGAAAGGACAC
TAA

Upstream 100 bases:

>100_bases
TAATTACAGGTTATTGATAAATAATAAATTATATTACCTTGTATATACTAGTTACATCATGTTAAAATGTAAGCGTTTCT
AAGAAAGGGGTAGCTCTTGT

Downstream 100 bases:

>100_bases
CTATGAATTTTAAAAATAAGGTTATTTACCAAATTTATCCCAAATCATTCTATGATTCTAACAACGATGGCATTGGAGAT
TTACAAGGAATTATCAAAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MESKYDLIKQDIANKIIHGIYPAGSYLPSENELCDLYGTSRETVRKALVLLLELGYIQKIKGKGSIVLDVSRFVFPVSGI
KSFKELNQSQNMHSTTKVLTLEPRLVPTKDFGLDQNSELEATYIERLRTINDEPIIIDIDYVLSKVVNDIPKMAAENSLY
EYFEDQLGLDISYATKTITVEEPTERQRQLLKIPPHKDVVVIRSMTYLNDTTLFQFTESIHRADKFSFVDFARRQKLKGH

Sequences:

>Translated_240_residues
MESKYDLIKQDIANKIIHGIYPAGSYLPSENELCDLYGTSRETVRKALVLLLELGYIQKIKGKGSIVLDVSRFVFPVSGI
KSFKELNQSQNMHSTTKVLTLEPRLVPTKDFGLDQNSELEATYIERLRTINDEPIIIDIDYVLSKVVNDIPKMAAENSLY
EYFEDQLGLDISYATKTITVEEPTERQRQLLKIPPHKDVVVIRSMTYLNDTTLFQFTESIHRADKFSFVDFARRQKLKGH
>Mature_240_residues
MESKYDLIKQDIANKIIHGIYPAGSYLPSENELCDLYGTSRETVRKALVLLLELGYIQKIKGKGSIVLDVSRFVFPVSGI
KSFKELNQSQNMHSTTKVLTLEPRLVPTKDFGLDQNSELEATYIERLRTINDEPIIIDIDYVLSKVVNDIPKMAAENSLY
EYFEDQLGLDISYATKTITVEEPTERQRQLLKIPPHKDVVVIRSMTYLNDTTLFQFTESIHRADKFSFVDFARRQKLKGH

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=26.8085106382979, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082252, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790540, Length=234, Percent_Identity=23.0769230769231, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27566; Mature: 27566

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKYDLIKQDIANKIIHGIYPAGSYLPSENELCDLYGTSRETVRKALVLLLELGYIQKI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHH
KGKGSIVLDVSRFVFPVSGIKSFKELNQSQNMHSTTKVLTLEPRLVPTKDFGLDQNSELE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
ATYIERLRTINDEPIIIDIDYVLSKVVNDIPKMAAENSLYEYFEDQLGLDISYATKTITV
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECEEEEEE
EEPTERQRQLLKIPPHKDVVVIRSMTYLNDTTLFQFTESIHRADKFSFVDFARRQKLKGH
CCHHHHHHHHCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESKYDLIKQDIANKIIHGIYPAGSYLPSENELCDLYGTSRETVRKALVLLLELGYIQKI
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHCCCCHHHHHHHHHHHHHHHHHHHH
KGKGSIVLDVSRFVFPVSGIKSFKELNQSQNMHSTTKVLTLEPRLVPTKDFGLDQNSELE
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCH
ATYIERLRTINDEPIIIDIDYVLSKVVNDIPKMAAENSLYEYFEDQLGLDISYATKTITV
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECEEEEEE
EEPTERQRQLLKIPPHKDVVVIRSMTYLNDTTLFQFTESIHRADKFSFVDFARRQKLKGH
CCHHHHHHHHCCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]